Cadmium induces the thymus apoptosis of pigs through ROS-dependent PTEN/PI3K/AKT signaling pathway

Cadmium induces apoptosis of pig lymph nodes by regulating the PI3K/AKT/HIF-1α pathway

(2021) Lu Yiming et al.   TOXICOLOGY

Histological changes, lipid metabolism, oxidative and endoplasmic reticulum stress in the liver of laying hens exposed to cadmium concentrations

(2020) M.K. Zhu et al.   POULTRY SCIENCE

MicroRNA profiling identifies biomarkers in head kidneys of common carp exposed to cadmium

(2020) Qi Liu et al.   CHEMOSPHERE

Sulfur dioxide induces vascular relaxation through PI3K/Akt/eNOS and NO/cGMP signaling pathways in rats

(2020) Q Zhang et al.   HUMAN & EXPERIMENTAL TOXICOLOGY

Chlorpyrifos induces the apoptosis and necroptosis of L8824 cells through the ROS/PTEN/PI3K/AKT axis

(2020) Lanqiao Wang et al.   JOURNAL OF HAZARDOUS MATERIALS

Whole transcriptome-based miRNA-mRNA network analysis revealed the mechanism of inflammation-immunosuppressive damage caused by cadmium in common carp spleens

(2020) Jianqing Chen et al.   SCIENCE OF THE TOTAL ENVIRONMENT

The role of PI3K/Akt/mTOR signaling in dose-dependent biphasic effects of glycine on vascular development

(2020) Kiyomi Tsuji-Tamura et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Leonurine protects against dexamethasone-induced cytotoxicity in pancreatic β-cells via PI3K/Akt signaling pathway

(2020) Wan Xu et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Valproate improves middle cerebral artery occlusion-induced ischemic cerebral disorders in mice and oxygen-glucose deprivation-induced injuries in microglia by modulating RMRP/PI3K/Akt axis

(2020) Xuetang Li et al.   BRAIN RESEARCH

Pb exposure triggers MAPK-dependent inflammation by activating oxidative stress and miRNA-155 expression in carp head kidney

(2020) Hongyuan Jing et al.   FISH & SHELLFISH IMMUNOLOGY

Bisphenol A regulates cytochrome P450 1B1 through miR-27b-3p and induces carp lymphocyte oxidative stress leading to apoptosis

(2020) Qingqing Liu et al.   FISH & SHELLFISH IMMUNOLOGY

Glyphosate induces lymphocyte cell dysfunction and apoptosis via regulation of miR-203 targeting of PIK3R1 in common carp (Cyprinus carpio L.)

(2020) Wei Wang et al.   FISH & SHELLFISH IMMUNOLOGY

MiR-708 inhibits MC3T3-E1 cells against H2O2-induced apoptosis through targeting PTEN

(2020) Wei Zhang et al.   Journal of Orthopaedic Surgery and Research

Cadmium exposure induces pyroptosis of lymphocytes in carp pronephros and spleens by activating NLRP3

(2020) Yiming Zhang et al.   ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY

Quercetin alleviates Cadmium-induced autophagy inhibition via TFEB-dependent lysosomal restoration in primary proximal tubular cells

(2020) Yuan Zhao et al.   ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY

Zinc offers splenic protection through suppressing PERK/IRE1-driven apoptosis pathway in common carp (Cyprinus carpio) under arsenic stress

(2020) Yu Wang et al.   ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY

Antagonistic effect of VDR/CREB1 pathway on cadmium-induced apoptosis in porcine spleen

(2020) Zhang Yiming et al.   ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY

Regulation of H2S-induced necroptosis and inflammation in broiler bursa of Fabricius by the miR-15b-5p/TGFBR3 axis and the involvement of oxidative stress in this process

(2020) Chi Qianru et al.   JOURNAL OF HAZARDOUS MATERIALS

Promotion of PTEN on apoptosis through PI3K/Akt signal in vascular smooth muscle cells of mice model of coronary heart disease

(2019) Sheng Wang et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Role of miR-731 and miR-2188-3p in mediating chlorpyrifos induced head kidney injury in common carp via targeting TLR and apoptosis pathways

(2019) Qi Liu et al.   AQUATIC TOXICOLOGY

Ammonia inhalation-mediated mir-202-5p leads to cardiac autophagy through PTEN/AKT/mTOR pathway

(2019) Houjuan Xing et al.   CHEMOSPHERE

Trehalose suppresses cadmium-activated Nrf2 signaling pathway to protect against spleen injury

(2019) Kui-Chao Qu et al.   ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY

Arsenic (III) or/and copper (II) exposure induce immunotoxicity through trigger oxidative stress, inflammation and immune imbalance in the bursa of chicken

(2019) Juanjuan Liu et al.   ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY

Copper (II) and/or arsenite-induced oxidative stress cascades apoptosis and autophagy in the skeletal muscles of chicken

(2018) Yu Wang et al.   CHEMOSPHERE

Interplay between elemental imbalance-related PI3K/Akt/mTOR-regulated apoptosis and autophagy in arsenic (III)-induced jejunum toxicity of chicken

(2018) Yu Wang et al.   ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH

Impact of cadmium exposure on swine enterocytes

(2018) E. Razzuoli et al.   TOXICOLOGY LETTERS

Puerarin reverses cadmium-induced lysosomal dysfunction in primary rat proximal tubular cells via inhibiting Nrf2 pathway

(2018) Li-Yuan Wang et al.   BIOCHEMICAL PHARMACOLOGY

Maduramicin induces cardiac muscle cell death by the ROS-dependent PTEN/Akt-Erk1/2 signaling pathway

(2018) Xin Chen et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Immunosuppression, oxidative stress, and glycometabolism disorder caused by cadmium in common carp (Cyprinus carpio L.): Application of transcriptome analysis in risk assessment of environmental contaminant cadmium

(2018) Jianqing Chen et al.   JOURNAL OF HAZARDOUS MATERIALS

Alterations in antioxidant function and cell apoptosis in duck spleen exposed to molybdenum and/or cadmium

(2017) Mengmeng Zhang et al.   Journal of Veterinary Science

Trehalose protects against cadmium-induced cytotoxicity in primary rat proximal tubular cells via inhibiting apoptosis and restoring autophagic flux

(2017) Xin-Yu Wang et al.   Cell Death & Disease

Anticancer effect of curcumin inhibits cell growth through miR-21/PTEN/Akt pathway in breast cancer cell

(2017) Xinzheng Wang et al.   Oncology Letters

Atorvastatin Inhibits Myocardial Apoptosis in a Swine Model of Coronary Microembolization by Regulating PTEN/PI3K/Akt Signaling Pathway

(2016) Jiangyou Wang et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Skin Aging-Dependent Activation of the PI3K Signaling Pathway via Downregulation of PTEN Increases Intracellular ROS in Human Dermal Fibroblasts

(2016) Eun-Mi Noh et al.   Oxidative Medicine and Cellular Longevity

MicroRNA-21 promotes cell proliferation, migration, and resistance to apoptosis through PTEN/PI3K/AKT signaling pathway in esophageal cancer

(2016) Yan-Ran Wu et al.   TUMOR BIOLOGY

Hepatic oxidative stress and inflammatory responses with cadmium exposure in male mice

(2015) Ling Liu et al.   ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY

Downregulation of PI3-K/Akt/PTEN pathway and activation of mitochondrial intrinsic apoptosis by Diclofenac and Curcumin in colon cancer

(2015) Chandan Rana et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Carryover of cadmium from feed in growing pigs

(2014) Ron L.A.P. Hoogenboom et al.   Food Additives and Contaminants Part A-Chemistry Analysis Control Exposure & Risk Assessment

Effect of Cd with or without Se supplementation on spermatogenesis and semen quality in the rooster (Gallus gallus)

(2013) E. Marettová et al.   Avian Biology Research

Simultaneous modulation of COX-2, p300, Akt, and Apaf-1 signaling by melatonin to inhibit proliferation and induce apoptosis in breast cancer cells

(2012) Jingshu Wang et al.   JOURNAL OF PINEAL RESEARCH

Changes in the Peritubular Tissue of Rat Testis after Cadmium Treatment

(2009) Elena Marettová et al.   BIOLOGICAL TRACE ELEMENT RESEARCH

Reactive oxygen species as universal constraints in life-history evolution

(2009) D. K. Dowling et al.   PROCEEDINGS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Role of oxidative stress in cadmium toxicity and carcinogenesis

(2009) Jie Liu et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Activation of Nrf2 in Defense against Cadmium-Induced Oxidative Stress†

(2008) Xiaoqing He et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Assessment of trace element contents of chicken products from turkey

(2008) Ozgur Dogan Uluozlu et al.   JOURNAL OF HAZARDOUS MATERIALS

The protection of selenium on ROS mediated-apoptosis by mitochondria dysfunction in cadmium-induced LLC-PK1 cells

(2008) Yi-jing Zhou et al.   TOXICOLOGY IN VITRO