Human spliceosomal snRNA sequence variants generate variant spliceosomes

VELCRO-IP RNA-seq reveals ribosome expansion segment function in translation genome-wide

(2021) Kathrin Leppek et al.   Cell Reports

The integrity of the U12 snRNA 3′ stem–loop is necessary for its overall stability

(2021) Antto J Norppa et al.   NUCLEIC ACIDS RESEARCH

Competition between maturation and degradation drives human snRNA 3′ end quality control

(2020) Rea M. Lardelli et al.   GENES & DEVELOPMENT

ISG20 and nuclear exosome promote destabilization of nascent transcripts for spliceosomal U snRNAs and U1 variants

(2020) Takahito Kawamoto et al.   GENES TO CELLS

Structural Insights into Nuclear pre-mRNA Splicing in Higher Eukaryotes

(2019) Berthold Kastner et al.   Cold Spring Harbor Perspectives in Biology

Mechanism of 5ʹ splice site transfer for human spliceosome activation

(2019) Clément Charenton et al.   SCIENCE

How to Recruit the Correct RNA Polymerase? Lessons from snRNA Genes

(2019) Oleksandr Dergai et al.   TRENDS IN GENETICS

Nuclear Pre-snRNA Export Is an Essential Quality Assurance Mechanism for Functional Spliceosomes

(2019) Daniel Becker et al.   Cell Reports

RNA components of the spliceosome regulate tissue- and cancer-specific alternative splicing

(2019) Heidi Dvinge et al.   GENOME RESEARCH

RNA ligation precedes the retrotransposition of U6/LINE-1 chimeric RNA

(2019) John B. Moldovan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Alternative Splicing Regulatory Networks: Functions, Mechanisms, and Evolution

(2019) Jernej Ule et al.   MOLECULAR CELL

Recurrent noncoding U1 snRNA mutations drive cryptic splicing in SHH medulloblastoma

(2019) Hiromichi Suzuki et al.   NATURE

The U1 spliceosomal RNA is recurrently mutated in multiple cancers

(2019) Shimin Shuai et al.   NATURE

RNA Splicing by the Spliceosome

(2019) Max E. Wilkinson et al.   Annual Review of Biochemistry

Regulation of alternative mRNA splicing: old players and new perspectives

(2018) Heidi Dvinge   FEBS LETTERS

The life of U6 small nuclear RNA, from cradle to grave

(2018) Allison L. Didychuk et al.   RNA

The Exon Junction Complex Undergoes a Compositional Switch that Alters mRNP Structure and Nonsense-Mediated mRNA Decay Activity

(2018) Justin W. Mabin et al.   Cell Reports

Multilayered Control of Alternative Splicing Regulatory Networks by Transcription Factors

(2017) Hong Han et al.   MOLECULAR CELL

Ensembl 2018

(2017) Daniel R Zerbino et al.   NUCLEIC ACIDS RESEARCH

Variant snRNPs: New players within the spliceosome system

(2017) Pilar Vazquez-Arango et al.   RNA Biology

Regulation of expression of human RNA polymerase II-transcribed snRNA genes

(2017) Joana Guiro et al.   Open Biology

Small non-coding RNA transcriptome of the NCI-60 cell line panel

(2017) Erin A. Marshall et al.   Scientific Data

A U1 snRNP–specific assembly pathway reveals the SMN complex as a versatile hub for RNP exchange

(2016) Byung Ran So et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Variant U1 snRNAs are implicated in human pluripotent stem cell maintenance and neuromuscular disease

(2016) Pilar Vazquez-Arango et al.   NUCLEIC ACIDS RESEARCH

Molecular architecture of the human U4/U6.U5 tri-snRNP

(2016) D. E. Agafonov et al.   SCIENCE

A U1 snRNP–specific assembly pathway reveals the SMN complex as a versatile hub for RNP exchange

(2016) Byung Ran So et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

The PRMT5 arginine methyltransferase: many roles in development, cancer and beyond

(2015) Nicole Stopa et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

U6 snRNA Pseudogenes: Markers of Retrotransposition Dynamics in Mammals

(2015) Aurélien J. Doucet et al.   MOLECULAR BIOLOGY AND EVOLUTION

Genome-Wide Identification of Fas/CD95 Alternative Splicing Regulators Reveals Links with Iron Homeostasis

(2015) J. Ramón Tejedor et al.   MOLECULAR CELL

Crystal structure of human U1 snRNP, a small nuclear ribonucleoprotein particle, reveals the mechanism of 5′ splice site recognition

(2015) Yasushi Kondo et al.   eLife

A day in the life of the spliceosome

(2014) A. Gregory Matera et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Ensembl 2015

(2014) Fiona Cunningham et al.   NUCLEIC ACIDS RESEARCH

Developmental Analysis of Spliceosomal snRNA Isoform Expression

(2014) Zhipeng Lu et al.   G3-Genes Genomes Genetics

Decreased number of Gemini of coiled bodies and U12 snRNA level in amyotrophic lateral sclerosis

(2013) Tomohiko Ishihara et al.   HUMAN MOLECULAR GENETICS

Alternative pre-mRNA splicing in neurons: growing up and extending its reach

(2013) Sika Zheng et al.   TRENDS IN GENETICS

Mutation of a U2 snRNA Gene Causes Global Disruption of Alternative Splicing and Neurodegeneration

(2012) Yichang Jia et al.   CELL

Differentially expressed, variant U1 snRNAs regulate gene expression in human cells

(2012) D. O'Reilly et al.   GENOME RESEARCH

Landscape of transcription in human cells

(2012) Sarah Djebali et al.   NATURE

New connections between splicing and human disease

(2012) Richard A. Padgett   TRENDS IN GENETICS

Genomic Study of RNA Polymerase II and III SNAPc-Bound Promoters Reveals a Gene Transcribed by Both Enzymes and a Broad Use of Common Activators

(2012) Nicole James Faresse et al.   PLoS Genetics

The significant other: splicing by the minor spliceosome

(2012) Janne J. Turunen et al.   Wiley Interdisciplinary Reviews-RNA

RSEM: accurate transcript quantification from RNA-Seq data with or without a reference genome

(2011) Bo Li et al.   BMC BIOINFORMATICS

Fast, scalable generation of high-quality protein multiple sequence alignments using Clustal Omega

(2011) F. Sievers et al.   Molecular Systems Biology

Structure of the spliceosomal U4 snRNP core domain and its implication for snRNP biogenesis

(2011) Adelaine K. W. Leung et al.   NATURE

Biogenesis of spliceosomal small nuclear ribonucleoproteins

(2011) Utz Fischer et al.   Wiley Interdisciplinary Reviews-RNA

Expansion of the eukaryotic proteome by alternative splicing

(2010) Timothy W. Nilsen et al.   NATURE

Recognition of atypical 5′ splice sites by shifted base-pairing to U1 snRNA

(2009) Xavier Roca et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Ultrafast and memory-efficient alignment of short DNA sequences to the human genome

(2009) Ben Langmead et al.   GENOME BIOLOGY

SMN Deficiency Causes Tissue-Specific Perturbations in the Repertoire of snRNAs and Widespread Defects in Splicing

(2008) Zhenxi Zhang et al.   CELL

Evolution of Spliceosomal snRNA Genes in Metazoan Animals

(2008) Manuela Marz et al.   JOURNAL OF MOLECULAR EVOLUTION

Tissue-specific splicing factor gene expression signatures

(2008) Ana Rita Grosso et al.   NUCLEIC ACIDS RESEARCH

Minor spliceosome components are predominantly localized in the nucleus

(2008) H. K. J. Pessa et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA