Time‐resolved proteomic profiling of cigarette smoke‐induced experimental chronic obstructive pulmonary disease

Cellular Senescence as a Mechanism and Target in Chronic Lung Diseases

(2019) Peter J Barnes et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Molecular links between COPD and lung cancer: new targets for drug discovery?

(2019) Gaetano Caramori et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

IL-22 and its receptors are increased in human and experimental COPD and contribute to pathogenesis

(2019) Malcolm R. Starkey et al.   EUROPEAN RESPIRATORY JOURNAL

Quantitative proteomic characterization of the lung extracellular matrix in chronic obstructive pulmonary disease and idiopathic pulmonary fibrosis

(2018) Emma Åhrman et al.   Journal of Proteomics

S100B as an antagonist to block the interaction between S100A1 and the RAGE V domain

(2018) Md. Imran Khan et al.   PLoS One

The DNA Repair Transcriptome in Severe COPD

(2018) Maor Sauler et al.   EUROPEAN RESPIRATORY JOURNAL

Transcriptome-wide analysis uncovers the targets of the RNA-binding protein MSI2 and effects of MSI2’s RNA-binding activity on IL-6 signaling

(2018) Sujitha Duggimpudi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Roles for T/B lymphocytes and ILC2s in experimental chronic obstructive pulmonary disease

(2018) Chantal Donovan et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Proteomic profiling of crocodile spermatozoa refutes the tenet that post-testicular maturation is restricted to mammals

(2018) Brett Nixon et al.   MOLECULAR & CELLULAR PROTEOMICS

Proteomic profiling of mouse epididymosomes reveals their contributions to post-testicular sperm maturation

(2018) Brett Nixon et al.   MOLECULAR & CELLULAR PROTEOMICS

The Overlap of Lung Tissue Transcriptome of Smoke Exposed Mice with Human Smoking and COPD

(2018) Ma’en Obeidat et al.   Scientific Reports

Heparin-binding epidermal growth factor (HB-EGF) drives EMT in patients with COPD: implications for disease pathogenesis and novel therapies

(2018) Mathew Suji Eapen et al.   LABORATORY INVESTIGATION

Increasing complexity and interactions of oxidative stress in chronic respiratory diseases: An emerging need for novel drug delivery systems

(2018) Kamal Dua et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Knockout of RAGE ameliorates mainstream cigarette smoke-induced airway inflammation in mice

(2017) Mei Chen et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

RNA binding protein Musashi-2 regulates PIWIL1 and TBX1 in mouse spermatogenesis

(2017) Jessie M. Sutherland et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Quantitative Proteomic Analysis of Optimal Cutting Temperature (OCT) Embedded Core-Needle Biopsy of Lung Cancer

(2017) Xiaozheng Zhao et al.   JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY

Mutant JAK3 phosphoproteomic profiling predicts synergism between JAK3 inhibitors and MEK/BCL2 inhibitors for the treatment of T-cell acute lymphoblastic leukemia

(2017) S Degryse et al.   LEUKEMIA

Alpha-1-antitrypsin deficiency: Genetic variations, clinical manifestations and therapeutic interventions

(2017) Younis Mohammad Hazari et al.   MUTATION RESEARCH-REVIEWS IN MUTATION RESEARCH

Cellular Senescence: A Translational Perspective

(2017) James L. Kirkland et al.   EBioMedicine

QuPath: Open source software for digital pathology image analysis

(2017) Peter Bankhead et al.   Scientific Reports

The hnRNP family: insights into their role in health and disease

(2016) Thomas Geuens et al.   HUMAN GENETICS

The Perseus computational platform for comprehensive analysis of (prote)omics data

(2016) Stefka Tyanova et al.   NATURE METHODS

Musashi-2 (MSI2) supports TGF-β signaling and inhibits claudins to promote non-small cell lung cancer (NSCLC) metastasis

(2016) Alexander E. Kudinov et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Animal models of COPD: What do they tell us?

(2016) Bernadette Jones et al.   RESPIROLOGY

ProNGF is a potential diagnostic biomarker for thyroid cancer

(2016) Sam Faulkner et al.   Oncotarget

DAMPs, ageing, and cancer: The ‘DAMP Hypothesis’

(2015) Jin Huang et al.   AGEING RESEARCH REVIEWS

Targeting PI3K-p110α Suppresses Influenza Virus Infection in Chronic Obstructive Pulmonary Disease

(2015) Alan Chen-Yu Hsu et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

CXCR2 Antagonist MK-7123. A Phase 2 Proof-of-Concept Trial for Chronic Obstructive Pulmonary Disease

(2015) Stephen I. Rennard et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Unravelling the complexity of COPD by microRNAs: it's a small world after all

(2015) Emmanuel T. Osei et al.   EUROPEAN RESPIRATORY JOURNAL

JAK–STAT pathway activation in COPD

(2015) Liang Yew-Booth et al.   EUROPEAN RESPIRATORY JOURNAL

Hallmarks of the ageing lung

(2015) Silke Meiners et al.   EUROPEAN RESPIRATORY JOURNAL

Transcriptional profiling and targeted proteomics reveals common molecular changes associated with cigarette smoke-induced lung emphysema development in five susceptible mouse strains

(2015) Maciej Cabanski et al.   INFLAMMATION RESEARCH

Global trends and projections for tobacco use, 1990–2025: an analysis of smoking indicators from the WHO Comprehensive Information Systems for Tobacco Control

(2015) Ver Bilano et al.   LANCET

Proteotranscriptomic Profiling of 231-BR Breast Cancer Cells: Identification of Potential Biomarkers and Therapeutic Targets for Brain Metastasis

(2015) Matthew D. Dun et al.   MOLECULAR & CELLULAR PROTEOMICS

Time- and compartment-resolved proteome profiling of the extracellular niche in lung injury and repair

(2015) H. B. Schiller et al.   Molecular Systems Biology

A pathogenic role for tumor necrosis factor-related apoptosis-inducing ligand in chronic obstructive pulmonary disease

(2015) T J Haw et al.   Mucosal Immunology

Inflammasomes in COPD and neutrophilic asthma

(2015) Richard Y Kim et al.   THORAX

Antagonism of miR-328 Increases the Antimicrobial Function of Macrophages and Neutrophils and Rapid Clearance of Non-typeable Haemophilus Influenzae (NTHi) from Infected Lung

(2015) Hock L. Tay et al.   PLoS Pathogens

Molecular mechanisms underlying variations in lung function: a systems genetics analysis

(2015) Ma'en Obeidat et al.   Lancet Respiratory Medicine

Let-7d microRNA affects mesenchymal phenotypic properties of lung fibroblasts

(2014) Luai Huleihel et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

S100A1 is released from ischemic cardiomyocytes and signals myocardial damage via Toll-like receptor 4

(2014) D. Rohde et al.   EMBO Molecular Medicine

Animal models of chronic obstructive pulmonary disease

(2014) Michael Fricker et al.   Expert Opinion on Drug Discovery

S100A8, S100A9 and S100A12 activate airway epithelial cells to produce MUC5AC via extracellular signal-regulated kinase and nuclear factor-κB pathways

(2014) Jin Hyun Kang et al.   IMMUNOLOGY

Importance of Mast Cell Prss31/Transmembrane Tryptase/Tryptase-γ in Lung Function and Experimental Chronic Obstructive Pulmonary Disease and Colitis

(2014) Philip M. Hansbro et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Epithelial-mesenchymal transition as a fundamental underlying pathogenic process in COPD airways: fibrosis, remodeling and cancer

(2014) Kaosia Nowrin et al.   Expert Review of Respiratory Medicine

Targeted Quantitation of Proteins by Mass Spectrometry

(2013) Daniel C. Liebler et al.   BIOCHEMISTRY

Causal analysis approaches in Ingenuity Pathway Analysis

(2013) Andreas Krämer et al.   BIOINFORMATICS

The Hallmarks of Aging

(2013) Carlos López-Otín et al.   CELL

Oxidative Stress in COPD

(2013) Paul A. Kirkham et al.   CHEST

Telomere length in circulating leukocytes is associated with lung function and disease

(2013) E. Albrecht et al.   EUROPEAN RESPIRATORY JOURNAL

Necroptosis: The Release of Damage-Associated Molecular Patterns and Its Physiological Relevance

(2013) Agnieszka Kaczmarek et al.   IMMUNITY

Corticosteroid resistance in patients with asthma and chronic obstructive pulmonary disease

(2013) Peter J. Barnes   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

A new short-term mouse model of chronic obstructive pulmonary disease identifies a role for mast cell tryptase in pathogenesis

(2013) Emma L. Beckett et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Levels of Components of the Urokinase-Type Plasminogen Activator System are Related to Chronic Obstructive Pulmonary Disease Parenchymal Destruction and Airway Remodelling

(2013) Y Zhang et al.   JOURNAL OF INTERNATIONAL MEDICAL RESEARCH

DAMPs activating innate and adaptive immune responses in COPD

(2013) S D Pouwels et al.   Mucosal Immunology

P38 inhibition in COPD; cautious optimism

(2013) Dave Singh   THORAX

PAMPs and DAMPs: signal 0s that spur autophagy and immunity

(2012) Daolin Tang et al.   IMMUNOLOGICAL REVIEWS

TiSH — a robust and sensitive global phosphoproteomics strategy employing a combination of TiO2, SIMAC, and HILIC

(2012) Kasper Engholm-Keller et al.   Journal of Proteomics

Global and regional mortality from 235 causes of death for 20 age groups in 1990 and 2010: a systematic analysis for the Global Burden of Disease Study 2010

(2012) Rafael Lozano et al.   LANCET

The Relationship between Telomere Length and Mortality in Chronic Obstructive Pulmonary Disease (COPD)

(2012) Jee Lee et al.   PLoS One

Apoptosis and necrosis: two different outcomes of cigarette smoke condensate-induced endothelial cell death

(2012) B Messner et al.   Cell Death & Disease

Suppressed Expression of T-Box Transcription Factors Is Involved in Senescence in Chronic Obstructive Pulmonary Disease

(2012) George K. Acquaah-Mensah et al.   PLoS Computational Biology

Pulmonary-intestinal cross-talk in mucosal inflammatory disease

(2011) S Keely et al.   Mucosal Immunology

An Official American Thoracic Society Public Policy Statement: Novel Risk Factors and the Global Burden of Chronic Obstructive Pulmonary Disease

(2010) Mark D. Eisner et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Skyline: an open source document editor for creating and analyzing targeted proteomics experiments

(2010) Brendan MacLean et al.   BIOINFORMATICS

A Genome-Wide Association Study in Chronic Obstructive Pulmonary Disease (COPD): Identification of Two Major Susceptibility Loci

(2009) Sreekumar G. Pillai et al.   PLoS Genetics