DAMPs activating innate and adaptive immune responses in COPD

Comment on “Cigarette Smoke-Induced Pulmonary Inflammation Is TLR4/MyD88 and IL-1R1/MyD88 Signaling Dependent”

(2014) Tania Maes et al.   JOURNAL OF IMMUNOLOGY

Cigarette Smoke-Induced Pulmonary Inflammation Is TLR4/MyD88 and IL-1R1/MyD88 Signaling Dependent

(2014) E. Doz et al.   JOURNAL OF IMMUNOLOGY

Necroptosis: The Release of Damage-Associated Molecular Patterns and Its Physiological Relevance

(2013) Agnieszka Kaczmarek et al.   IMMUNITY

Alcohol-induced IL-1β in the brain is mediated by NLRP3/ASC inflammasome activation that amplifies neuroinflammation

(2013) Dora Lippai et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Mitochondrial DAMPs Increase Endothelial Permeability through Neutrophil Dependent and Independent Pathways

(2013) Shiqin Sun et al.   PLoS One

The Dendritic Cell Response to Classic, Emerging, and Homeostatic Danger Signals. Implications for Autoimmunity

(2013) Paul M. Gallo et al.   Frontiers in Immunology

Endoplasmic reticulum stress signal impairs erythropoietin production: a role for ATF4

(2012) Chih-Kang Chiang et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Genetic Ablation of theFpr1Gene Confers Protection from Smoking-Induced Lung Emphysema in Mice

(2012) Silvia Cardini et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Galectins in acute and chronic inflammation

(2012) Fu-Tong Liu et al.   Annals of the New York Academy of Sciences

Endoplasmic Reticulum Stress in Chronic Obstructive Lung Diseases

(2012) C. M.P. Ribeiro et al.   CURRENT MOLECULAR MEDICINE

A novel pathway combining calreticulin exposure and ATP secretion in immunogenic cancer cell death

(2012) Abhishek D Garg et al.   EMBO JOURNAL

Extracellular matrix composition in COPD

(2012) Raquel Annoni et al.   EUROPEAN RESPIRATORY JOURNAL

Cigarette smoke induces endoplasmic reticulum stress response and proteasomal dysfunction in human alveolar epithelial cells

(2012) Anita Somborac-Bačura et al.   EXPERIMENTAL PHYSIOLOGY

Pathogenesis of chronic obstructive pulmonary disease

(2012) Rubin M. Tuder et al.   JOURNAL OF CLINICAL INVESTIGATION

Mutually exclusive redox forms of HMGB1 promote cell recruitment or proinflammatory cytokine release

(2012) Emilie Venereau et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Galectin-3 Facilitates Neutrophil Recruitment as an Innate Immune Response to a Parasitic Protozoa Cutaneous Infection

(2012) P. Bhaumik et al.   JOURNAL OF IMMUNOLOGY

Danger-associated molecular patterns (DAMPs) in acute lung injury

(2012) Leslie B Tolle et al.   JOURNAL OF PATHOLOGY

Danger Signals Activating the Immune Response after Trauma

(2012) Stefanie Hirsiger et al.   MEDIATORS OF INFLAMMATION

A Perspective on Mammalian Caspases as Positive and Negative Regulators of Inflammation

(2012) Seamus J. Martin et al.   MOLECULAR CELL

Systemic Biomarkers of Neutrophilic Inflammation, Tissue Injury and Repair in COPD Patients with Differing Levels of Disease Severity

(2012) Debra A. Cockayne et al.   PLoS One

The effect of human antibacterial peptide LL-37 in the pathogenesis of chronic obstructive pulmonary disease

(2012) Yuan-Yuan Jiang et al.   RESPIRATORY MEDICINE

Changes in prevalence and load of airway bacteria using quantitative PCR in stable and exacerbated COPD

(2012) Davinder S Garcha et al.   THORAX

High-mobility group box family of proteins: ligand and sensor for innate immunity

(2012) Hideyuki Yanai et al.   TRENDS IN IMMUNOLOGY

Viral Infection is Associated with an Increased Proinflammatory Response in Chronic Obstructive Pulmonary Disease

(2012) Raquel Almansa et al.   VIRAL IMMUNOLOGY

Mitochondrial Evolution

(2012) M. W. Gray   Cold Spring Harbor Perspectives in Biology

Apoptosis and necrosis: two different outcomes of cigarette smoke condensate-induced endothelial cell death

(2012) B Messner et al.   Cell Death & Disease

GOLD guidelines 2011: what are the implications for primary care?

(2012) Kevin Gruffydd-Jones   Primary Care Respiratory Journal

Matrix Proteins from Smoke-Exposed Fibroblasts Are Pro-proliferative

(2011) David I. Krimmer et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Effects of Bacterial Infection on Airway Antimicrobial Peptides and Proteins in COPD

(2011) Ganapathi Iyer Parameswaran et al.   CHEST

Validity of HMGB1 measurement in epithelial lining fluid in patients with COPD

(2011) Hiroshi Kanazawa et al.   EUROPEAN JOURNAL OF CLINICAL INVESTIGATION

Soluble RAGE is deficient in neutrophilic asthma and COPD

(2011) M. B. Sukkar et al.   EUROPEAN RESPIRATORY JOURNAL

Antimicrobial peptides important in innate immunity

(2011) Andreas Cederlund et al.   FEBS Journal

Dysregulation of TIM-3-Galectin-9 Pathway in the Cystic Fibrosis Airways

(2011) I. Vega-Carrascal et al.   JOURNAL OF IMMUNOLOGY

S100A8 and S100A9: New Insights into Their Roles in Malignancy

(2011) Geetha Srikrishna   Journal of Innate Immunity

Dynamics of heat shock protein 60 in endothelial cells exposed to cigarette smoke extract

(2011) Simone Barbara Kreutmayer et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Dangers Within: DAMP Responses to Damage and Cell Death in Kidney Disease

(2011) D. L. Rosin et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

New insights into the immunology of chronic obstructive pulmonary disease

(2011) Guy G Brusselle et al.   LANCET

Unknown

(2011) Changchun Hou et al.   MOLECULAR MEDICINE

Novel Sulfated Polysaccharides Disrupt Cathelicidins, Inhibit RAGE and Reduce Cutaneous Inflammation in a Mouse Model of Rosacea

(2011) Jianxing Zhang et al.   PLoS One

RIP1-Dependent and Independent Effects of Necrostatin-1 in Necrosis and T Cell Activation

(2011) YoungSik Cho et al.   PLoS One

Increased Expression of Beta-Defensin 1 (DEFB1) in Chronic Obstructive Pulmonary Disease

(2011) Ellen Andresen et al.   PLoS One

Convergent Sets of Data from In Vivo and In Vitro Methods Point to an Active Role of Hsp60 in Chronic Obstructive Pulmonary Disease Pathogenesis

(2011) Francesco Cappello et al.   PLoS One

Long-term exposure to cigarette smoke impairs lung function and increases HMGB-1 expression in mice

(2011) Frank Silva Bezerra et al.   RESPIRATORY PHYSIOLOGY & NEUROBIOLOGY

Emerging role of damage-associated molecular patterns derived from mitochondria in inflammation

(2011) Dmitri V. Krysko et al.   TRENDS IN IMMUNOLOGY

Expression of High-Mobility Group Box 1 and of Receptor for Advanced Glycation End Products in Chronic Obstructive Pulmonary Disease

(2010) Nassima Ferhani et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Extracellular Adenosine Triphosphate and Chronic Obstructive Pulmonary Disease

(2010) Marek Lommatzsch et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

P2X7Receptor Signaling in the Pathogenesis of Smoke-Induced Lung Inflammation and Emphysema

(2010) Monica Lucattelli et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Galectins: regulators of acute and chronic inflammation

(2010) Fu-Tong Liu et al.   Annals of the New York Academy of Sciences

HMGB1 and RAGE in Inflammation and Cancer

(2010) Gary P. Sims et al.   Annual Review of Immunology

Impairment of phagocytosis of apoptotic cells and its role in chronic airway diseases

(2010) Olga Krysko et al.   APOPTOSIS

Pattern Recognition Receptors and Inflammation

(2010) Osamu Takeuchi et al.   CELL

ATP and the pathogenesis of COPD

(2010) Esmaeil Mortaz et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Cigarette smoke enhances  -defensin 2 expression in rat airways via nuclear factor- B activation

(2010) L. Chen et al.   EUROPEAN RESPIRATORY JOURNAL

Smoke exposure as a determinant of autoantibody titre in  1-antitrypsin deficiency and COPD

(2010) A. M. Wood et al.   EUROPEAN RESPIRATORY JOURNAL

Reduced soluble receptor for advanced glycation end-products in COPD

(2010) D. J. Smith et al.   EUROPEAN RESPIRATORY JOURNAL

Innate immunity proteins in chronic obstructive pulmonary disease and idiopathic pulmonary fibrosis

(2010) Maria Tsoumakidou et al.   EXPERIMENTAL LUNG RESEARCH

TLR4 upregulation underpins airway neutrophilia in smokers with chronic obstructive pulmonary disease and acute respiratory failure

(2010) Elisabetta Pace et al.   HUMAN IMMUNOLOGY

Purinergic Receptor Inhibition Prevents the Development of Smoke-Induced Lung Injury and Emphysema

(2010) S. Cicko et al.   JOURNAL OF IMMUNOLOGY

Dual Role of Heat Shock Proteins as Regulators of Apoptosis and Innate Immunity

(2010) Anne-Laure Joly et al.   Journal of Innate Immunity

Circulating mitochondrial DAMPs cause inflammatory responses to injury

(2010) Qin Zhang et al.   NATURE

Intravascular Danger Signals Guide Neutrophils to Sites of Sterile Inflammation

(2010) B. McDonald et al.   SCIENCE

Mitochondrial Peptides Are Potent Immune Activators That Activate Human Neutrophils Via FPR-1

(2010) Mustafa Raoof et al.   JOURNAL OF TRAUMA-INJURY INFECTION AND CRITICAL CARE

Heightened Endoplasmic Reticulum Stress in the Lungs of Patients with Chronic Obstructive Pulmonary Disease

(2009) Deepti Malhotra et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Absence of Proteinase-Activated Receptor-1 Signaling in Mice Confers Protection from fMLP-Induced Goblet Cell Metaplasia

(2009) Luigi Atzori et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Enhanced Deposition of Low-Molecular-Weight Hyaluronan in Lungs of Cigarette Smoke–Exposed Mice

(2009) Ken R. Bracke et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Immunogenic cell death modalities and their impact on cancer treatment

(2009) Oliver Kepp et al.   APOPTOSIS

ATP in the pathogenesis of lung emphysema

(2009) Esmaeil Mortaz et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Galectins in innate immunity: dual functions of host soluble β-galactoside-binding lectins as damage-associated molecular patterns (DAMPs) and as receptors for pathogen-associated molecular patterns (PAMPs)

(2009) Sachiko Sato et al.   IMMUNOLOGICAL REVIEWS

The alarmin HMGB1 acts in synergy with endogenous and exogenous danger signals to promote inflammation

(2009) Hulda Sigridur Hreggvidsdottir et al.   JOURNAL OF LEUKOCYTE BIOLOGY

HMGB1 loves company

(2009) Marco E. Bianchi   JOURNAL OF LEUKOCYTE BIOLOGY

Genome-wide association study identifies five loci associated with lung function

(2009) Emmanouela Repapi et al.   NATURE GENETICS

Meta-analyses of genome-wide association studies identify multiple loci associated with pulmonary function

(2009) Dana B Hancock et al.   NATURE GENETICS

Activation of the NLRP3 inflammasome in dendritic cells induces IL-1β–dependent adaptive immunity against tumors

(2009) François Ghiringhelli et al.   NATURE MEDICINE

Immunologic Aspects of Chronic Obstructive Pulmonary Disease

(2009) Manuel G. Cosio et al.   NEW ENGLAND JOURNAL OF MEDICINE

Cigarette smoke induces endoplasmic reticulum stress and the unfolded protein response in normal and malignant human lung cells

(2008) Ellen Jorgensen et al.   BMC CANCER

Murine  -defensin 2 promotes TLR-4/MyD88-mediated and NF- B-dependent atypical death of APCs via activation of TNFR2

(2008) A. Biragyn et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Different expression ratio of S100A8/A9 and S100A12 in acute and chronic lung diseases

(2008) Eva Lorenz et al.   RESPIRATORY MEDICINE

Cigarette Smoke Induces an Unfolded Protein Response in the Human Lung

(2007) Steven G. Kelsen et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY