IL-22 and its receptors are increased in human and experimental COPD and contribute to pathogenesis

Functional effects of the microbiota in chronic respiratory disease

(2019) Kurtis F Budden et al.   Lancet Respiratory Medicine

Th17 cytokines: novel potential therapeutic targets for COPD pathogenesis and exacerbations

(2017) Olivier Le Rouzic et al.   EUROPEAN RESPIRATORY JOURNAL

MicroRNA-21 drives severe, steroid-insensitive experimental asthma by amplifying phosphoinositide 3-kinase–mediated suppression of histone deacetylase 2

(2017) Richard Y. Kim et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Th22 Cells Form a Distinct Th Lineage from Th17 Cells In Vitro with Unique Transcriptional Properties and Tbet-Dependent Th1 Plasticity

(2017) Maximilian W. Plank et al.   JOURNAL OF IMMUNOLOGY

Interleukin-22 ameliorated renal injury and fibrosis in diabetic nephropathy through inhibition of NLRP3 inflammasome activation

(2017) Shaofei Wang et al.   Cell Death & Disease

Suppressor of cytokine signaling (SOCS)5 ameliorates influenza infection via inhibition of EGFR signaling

(2017) Lukasz Kedzierski et al.   eLife

Interleukin-22 protects against non-typeable Haemophilus influenzae infection: alteration during chronic obstructive pulmonary disease

(2016) R Sharan et al.   Mucosal Immunology

Emerging pathogenic links between microbiota and the gut–lung axis

(2016) Kurtis F. Budden et al.   NATURE REVIEWS MICROBIOLOGY

Animal models of COPD: What do they tell us?

(2016) Bernadette Jones et al.   RESPIROLOGY

Characterization and Quantification of Innate Lymphoid Cell Subsets in Human Lung

(2016) Katrien C. De Grove et al.   PLoS One

Targeting PI3K-p110α Suppresses Influenza Virus Infection in Chronic Obstructive Pulmonary Disease

(2015) Alan Chen-Yu Hsu et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Interleukin-22: Immunobiology and Pathology

(2015) Jarrod A. Dudakov et al.   Annual Review of Immunology

Neutrophil proteases alter the interleukin-22-receptor-dependent lung antimicrobial defence

(2015) Antoine Guillon et al.   EUROPEAN RESPIRATORY JOURNAL

A pathogenic role for tumor necrosis factor-related apoptosis-inducing ligand in chronic obstructive pulmonary disease

(2015) T J Haw et al.   Mucosal Immunology

Macrolide therapy suppresses key features of experimental steroid-sensitive and steroid-insensitive asthma

(2015) Ama-Tawiah Essilfie et al.   THORAX

IL-22 Defect During Streptococcus pneumoniae Infection Triggers Exacerbation of Chronic Obstructive Pulmonary Disease

(2015) Muriel Pichavant et al.   EBioMedicine

Interleukin-22 exacerbates airway inflammation induced by short-term exposure to cigarette smoke in mice

(2014) Jiu-rong Li et al.   ACTA PHARMACOLOGICA SINICA

Animal models of chronic obstructive pulmonary disease

(2014) Michael Fricker et al.   Expert Opinion on Drug Discovery

Importance of Mast Cell Prss31/Transmembrane Tryptase/Tryptase-γ in Lung Function and Experimental Chronic Obstructive Pulmonary Disease and Colitis

(2014) Philip M. Hansbro et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

IL-22 Is Essential for Lung Epithelial Repair following Influenza Infection

(2013) Derek A. Pociask et al.   AMERICAN JOURNAL OF PATHOLOGY

Neutrophils and emerging targets for treatment in chronic obstructive pulmonary disease

(2013) Mariska Meijer et al.   Expert Review of Clinical Immunology

Corticosteroid resistance in patients with asthma and chronic obstructive pulmonary disease

(2013) Peter J. Barnes   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

A new short-term mouse model of chronic obstructive pulmonary disease identifies a role for mast cell tryptase in pathogenesis

(2013) Emma L. Beckett et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Tumor necrosis factor-related apoptosis-inducing ligand translates neonatal respiratory infection into chronic lung disease

(2013) M R Starkey et al.   Mucosal Immunology

Oxidative stress-mediated iNKT-cell activation is involved in COPD pathogenesis

(2013) M Pichavant et al.   Mucosal Immunology

A gene expression signature of emphysema-related lung destruction and its reversal by the tripeptide GHK

(2013) Joshua D Campbell et al.   Genome Medicine

Global and regional mortality from 235 causes of death for 20 age groups in 1990 and 2010: a systematic analysis for the Global Burden of Disease Study 2010

(2012) Rafael Lozano et al.   LANCET

Constitutive production of IL-13 promotes early-life Chlamydia respiratory infection and allergic airway disease

(2012) M R Starkey et al.   Mucosal Immunology

Cigarette Smoke Induction of Osteopontin (SPP1) Mediates TH17 Inflammation in Human and Experimental Emphysema

(2012) M. Shan et al.   Science Translational Medicine

Pulmonary-intestinal cross-talk in mucosal inflammatory disease

(2011) S Keely et al.   Mucosal Immunology

Early-life chlamydial lung infection enhances allergic airways disease through age-dependent differences in immunopathology

(2010) Jay C. Horvat et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY