Endoplasmic Reticulum Stress in Diabetic Nephrology: Regulation, Pathological Role, and Therapeutic Potential

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Quercetin‑conjugated superparamagnetic iron oxide nanoparticles modulate glucose metabolism-related genes and miR-29 family in the hippocampus of diabetic rats

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Pyruvate alleviates high glucose‐induced endoplasmic reticulum stress and apoptosis in HK‐2 Cells

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AdipoRon Protects against Tubular Injury in Diabetic Nephropathy by Inhibiting Endoplasmic Reticulum Stress

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Curcumin attenuates angiotensin II‐induced podocyte injury and apoptosis by inhibiting endoplasmic reticulum stress

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Endoplasmic Reticulum Stress and Unfolded Protein Response in Neurodegenerative Diseases

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Trichostatin A increases BDNF protein expression by improving XBP-1s/ATF6/GRP78 axis in Schwann cells of diabetic peripheral neuropathy

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Arctigenin ameliorates renal impairment and inhibits endoplasmic reticulum stress in diabetic db/db mice

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Dapagliflozin rescues endoplasmic reticulum stress-mediated cell death

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Protein arginine methyltranferase-1 induces ER stress and epithelial-mesenchymal transition in renal tubular epithelial cells and contributes to diabetic nephropathy

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Deep proteome profiling of the hippocampus in the 5XFAD mouse model reveals biological process alterations and a novel biomarker of Alzheimer’s disease

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Hepatic triglyceride accumulation via endoplasmic reticulum stress-induced SREBP-1 activation is regulated by ceramide synthases

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High Glucose-Induced Podocyte Injury Involves Activation of Mammalian Target of Rapamycin (mTOR)-Induced Endoplasmic Reticulum (ER) Stress

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Quercetin improves endothelial function in diabetic rats through inhibition of endoplasmic reticulum stress-mediated oxidative stress

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ROS signaling and ER stress in cardiovascular disease

(2018) Cristhiaan D. Ochoa et al.   MOLECULAR ASPECTS OF MEDICINE

Emodin mitigates podocytes apoptosis induced by endoplasmic reticulum stress through the inhibition of the PERK pathway in diabetic nephropathy

(2018) Nianxiu Tian et al.   Drug Design Development and Therapy

MiR-4756 promotes albumin-induced renal tubular epithelial cell epithelial-to-mesenchymal transition and endoplasmic reticulum stress via targeting Sestrin2

(2018) Yijie Jia et al.   JOURNAL OF CELLULAR PHYSIOLOGY

ER stress-related ATF6 upregulates CIP2A and contributes to poor prognosis of colon cancer

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Protective effects of Astragaloside IV on endoplasmic reticulum stress-induced renal tubular epithelial cells apoptosis in type 2 diabetic nephropathy rats

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Endoplasmic reticulum stress and unfolded protein response profile in quadriceps of sarcopenic patients with respiratory diseases

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Emerging roles of ER stress and unfolded protein response pathways in skeletal muscle health and disease

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Endoplasmic reticulum stress, the unfolded protein response and autophagy in kidney diseases

(2017) Andrey V. Cybulsky   Nature Reviews Nephrology

Endoplasmic reticulum stress participates in inflammation-accelerated, lipid-mediated injury of human glomerular mesangial cells

(2017) Haiping Yang et al.   NEPHROLOGY

EGFR inhibition attenuates diabetic nephropathy through decreasing ROS and endoplasmic reticulum stress

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Rtn1a-Mediated Endoplasmic Reticulum Stress in Podocyte Injury and Diabetic Nephropathy

(2017) Ying Fan et al.   Scientific Reports

Astragaloside IV protects against podocyte injury via SERCA2-dependent ER stress reduction and AMPKα-regulated autophagy induction in streptozotocin-induced diabetic nephropathy

(2017) Hengjiang Guo et al.   Scientific Reports

Ginkgolide K protects the heart against endoplasmic reticulum stress injury by activating the inositol-requiring enzyme 1α/X box-binding protein-1 pathway

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Asymmetric dimethylarginine (ADMA) treatment induces apoptosis in cultured rat mesangial cells via endoplasmic reticulum stress activation

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Grass carp (Ctenopharyngodon idella) ATF6 (activating transcription factor 6) modulates the transcriptional level of GRP78 and GRP94 in CIK cells

(2016) Xiangqin Wang et al.   FISH & SHELLFISH IMMUNOLOGY

Advanced oxidation protein products induce endothelial-to-mesenchymal transition in human renal glomerular endothelial cells through induction of endoplasmic reticulum stress

(2016) Xiujie Liang et al.   JOURNAL OF DIABETES AND ITS COMPLICATIONS

Huangkui capsule, an extract from Abelmoschus manihot (L.) medic, improves diabetic nephropathy via activating peroxisome proliferator–activated receptor (PPAR)-α/γ and attenuating endoplasmic reticulum stress in rats

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Urotensin II Induces ER Stress and EMT and Increase Extracellular Matrix Production in Renal Tubular Epithelial Cell in Early Diabetic Mice

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Autophagy in kidney disease and aging: lessons from rodent models

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Ursodeoxycholic acid and 4-phenylbutyrate prevent endoplasmic reticulum stress-induced podocyte apoptosis in diabetic nephropathy

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Angiopoietin-1 attenuates angiotensin II-induced ER stress in glomerular endothelial cells via a Tie2 receptor/ERK1/2-p38 MAPK-dependent mechanism

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The Role of Endoplasmic Reticulum Stress in Human Pathology

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Unfolded Protein Response and PERK Kinase as a New Therapeutic Target in the Pathogenesis of Alzheimer’s Disease

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Cystatin C attenuates insulin signaling transduction by promoting endoplasmic reticulum stress in hepatocytes

(2015) Xiaolin Ji et al.   FEBS LETTERS

Role of the ER stress in prostaglandin E2/E-prostanoid 2 receptor involved TGF-β1-induced mice mesangial cell injury

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Fatty Acid-Binding Protein 4 mediates apoptosis via endoplasmic reticulum stress in mesangial cells of diabetic nephropathy

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Oleanolic acid andN-acetylcysteine ameliorate diabetic nephropathy through reduction of oxidative stress and endoplasmic reticulum stress in a type 2 diabetic rat model

(2015) Eun Soo Lee et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

The Roles of Endoplasmic Reticulum Overload Response Induced by HCV and NS4B Protein in Human Hepatocyte Viability and Virus Replication

(2015) Lingbao Kong et al.   PLoS One

Epidermal Growth Factor Receptor Inhibition Slows Progression of Diabetic Nephropathy in Association With a Decrease in Endoplasmic Reticulum Stress and an Increase in Autophagy

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The Inhibitory Effect of Quercetin on Asymmetric Dimethylarginine-Induced Apoptosis Is Mediated by the Endoplasmic Reticulum Stress Pathway in Glomerular Endothelial Cells

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Protective effects of aliskiren and valsartan in mice with diabetic nephropathy

(2014) Weidong Wang et al.   JOURNAL OF THE RENIN-ANGIOTENSIN-ALDOSTERONE SYSTEM

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(2014) Mitsuo Kato et al.   Nature Reviews Nephrology

Free Fatty Acids and Their Metabolism Affect Function and Survival of Podocytes

(2014) Jonas Sieber et al.   Frontiers in Endocrinology

Receptor for advanced glycation end-products promotes premature senescence of proximal tubular epithelial cells via activation of endoplasmic reticulum stress-dependent p21 signaling

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Suppression of XBP1S Mediates High Glucose-Induced Oxidative Stress and Extracellular Matrix Synthesis in Renal Mesangial Cell and Kidney of Diabetic Rats

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Autophagy: Emerging Therapeutic Target for Diabetic Nephropathy

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Endoplasmic Reticulum Stress and Type 2 Diabetes

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ER stress negatively regulates AKT/TSC/mTOR pathway to enhance autophagy

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Translational control of the sterol-regulatory transcription factor SREBP-1 mRNA in response to serum starvation or ER stress is mediated by an internal ribosome entry site

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Cannabinoid receptor 1 mediates palmitic acid-induced apoptosis via endoplasmic reticulum stress in human renal proximal tubular cells

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ACE-inhibitor Suppresses the Apoptosis Induced by Endoplasmic Reticulum Stress in Renal Tubular in Experimental Diabetic Rats

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Asymmetric dimethylarginine is closely associated with the development and progression of nephropathy in patients with type 2 diabetes

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Urinary Fatty Acids and Liver-Type Fatty Acid Binding Protein in Diabetic Nephropathy

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Hepatitis C virus NS4B induces unfolded protein response and endoplasmic reticulum overload response-dependent NF-κB activation

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Effect of Taurine-Conjugated Ursodeoxycholic Acid on Endoplasmic Reticulum Stress and Apoptosis Induced by Advanced Glycation End Products in Cultured Mouse Podocytes

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Oleanolic acid and related derivatives as medicinally important compounds

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Proteinuria and Hyperglycemia Induce Endoplasmic Reticulum Stress

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