Trichostatin A increases BDNF protein expression by improving XBP-1s/ATF6/GRP78 axis in Schwann cells of diabetic peripheral neuropathy

Activation of AMPK pathway compromises Rab11 downregulation-mediated inhibition of Schwann cell proliferation in a Glut1 and Glut3-dependent manner

(2020) Fan Li et al.   NEUROSCIENCE LETTERS

Rescue of HSP70 in Spinal Neurons Alleviates Opioids-Induced Hyperalgesia via the Suppression of Endoplasmic Reticulum Stress in Rodents

(2020) Tong-Tong Lin et al.   Frontiers in Cell and Developmental Biology

Sulforaphane attenuates apoptosis of hippocampal neurons induced by high glucose via regulating endoplasmic reticulum

(2020) Liujiu Tang et al.   NEUROCHEMISTRY INTERNATIONAL

NLRP6 suppresses gastric cancer growth via GRP78 ubiquitination

(2020) Xinyue Wang et al.   EXPERIMENTAL CELL RESEARCH

Enhancing PPARγ by HDAC inhibition reduces foam cell formation and atherosclerosis in ApoE deficient mice

(2020) Qi Gao et al.   PHARMACOLOGICAL RESEARCH

Hepatic Sdf2l1 controls feeding-induced ER stress and regulates metabolism

(2019) Takayoshi Sasako et al.   Nature Communications

The histone deacetylase class I, II inhibitor trichostatin A delays peripheral neurodegeneration

(2019) Muwoong Kim et al.   JOURNAL OF MOLECULAR HISTOLOGY

STAT3 phosphorylation mediates high glucose–impaired cell autophagy in an HDAC1-dependent and -independent manner in Schwann cells of diabetic peripheral neuropathy

(2019) Wei Du et al.   FASEB JOURNAL

The Akt/mTOR cascade mediates high glucose-induced reductions in BDNF via DNMT1 in Schwann cells in diabetic peripheral neuropathy

(2019) Cui-Hong Zhang et al.   EXPERIMENTAL CELL RESEARCH

Small Molecules to Improve ER Proteostasis in Disease

(2019) Vicente Gonzalez-Teuber et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Sarm1 Gene Deficiency Attenuates Diabetic Peripheral Neuropathy in Mice

(2019) Yalan Cheng et al.   DIABETES

Epigenetic role of thymoquinone: impact on cellular mechanism and cancer therapeutics

(2019) Md. Asaduzzaman Khan et al.   DRUG DISCOVERY TODAY

From molecular promise to preclinical results: HDAC inhibitors in the race for healthy aging drugs

(2019) Rebecca L McIntyre et al.   EMBO Molecular Medicine

Overexpression of Sirtuin 1 protein in neurons prevents and reverses experimental diabetic neuropathy

(2019) Krish Chandrasekaran et al.   BRAIN

Activation of unfolded protein response pathway is important for valproic acid mediated increase in immunoglobulin G productivity in recombinant Chinese hamster ovary cells

(2017) Kamal Prashad Segar et al.   JOURNAL OF BIOSCIENCE AND BIOENGINEERING

Activation of sirtuin 1 by catalpol-induced down-regulation of microRNA-132 attenuates endoplasmic reticulum stress in colitis

(2017) Yongjian Xiong et al.   PHARMACOLOGICAL RESEARCH

Therapeutic implications of toll-like receptors in peripheral neuropathic pain

(2017) Krishan K. Thakur et al.   PHARMACOLOGICAL RESEARCH

TSA protects H9c2 cells against thapsigargin-induced apoptosis related to endoplasmic reticulum stress-mediated mitochondrial injury

(2017) Zhiping Li et al.   SAUDI PHARMACEUTICAL JOURNAL

Sulforaphane epigenetically enhances neuronal BDNF expression and TrkB signaling pathways

(2016) Jisung Kim et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Neurorestoration induced by the HDAC inhibitor sodium valproate in the lactacystin model of Parkinson's is associated with histone acetylation and up-regulation of neurotrophic factors

(2015) Ian F Harrison et al.   BRITISH JOURNAL OF PHARMACOLOGY

Histone Acetylation Enzymes Coordinate Metabolism and Gene Expression

(2015) Yuan Shen et al.   TRENDS IN PLANT SCIENCE

Modulation of endoplasmic reticulum chaperone GRP78 by high glucose in hippocampus of streptozotocin-induced diabetic mice and C6 astrocytic cells

(2013) Daniella P.K. Wong et al.   NEUROCHEMISTRY INTERNATIONAL

Trichostatin A Ameliorates Myocardial Ischemia/Reperfusion Injury Through Inhibition of Endoplasmic Reticulum Stress-induced Apoptosis

(2012) Ling Yu et al.   ARCHIVES OF MEDICAL RESEARCH

ATF6alpha Promotes Astroglial Activation and Neuronal Survival in a Chronic Mouse Model of Parkinson’s Disease

(2012) Koji Hashida et al.   PLoS One

Phosphodiesterase-5 is a therapeutic target for peripheral neuropathy in diabetic mice

(2011) L. Wang et al.   NEUROSCIENCE

Histone Deacetylase Inhibitor Valproic Acid Inhibits Cancer Cell Proliferation via Down-regulation of the Alzheimer Amyloid Precursor Protein

(2010) Vivek Venkataramani et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Endoplasmic reticulum stress in liver disease

(2010) Harmeet Malhi et al.   JOURNAL OF HEPATOLOGY

Reduced NGF secretion by Schwann cells under the high glucose condition decreases neurite outgrowth of DRG neurons

(2008) Takahiro Tosaki et al.   EXPERIMENTAL NEUROLOGY