Refining the approach to vaccines against influenza A viruses with pandemic potential

Post-H1N1 Narcolepsy-Cataplexy

(2017) Yves Dauvilliers et al.   SLEEP

Natural T Cell–mediated Protection against Seasonal and Pandemic Influenza. Results of the Flu Watch Cohort Study

(2015) Andrew C. Hayward et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Comparison of Pandemrix and Arepanrix, two pH1N1 AS03-adjuvanted vaccines differentially associated with narcolepsy development

(2015) Louis Jacob et al.   BRAIN BEHAVIOR AND IMMUNITY

Pandemic preparedness with live attenuated influenza vaccines based on A/Leningrad/134/17/57 master donor virus

(2015) Larisa Rudenko et al.   Expert Review of Vaccines

Safety and Immunogenicity of a Single Low Dose or High Dose of Clade 2 Influenza A(H5N1) Inactivated Vaccine in Adults Previously Primed With Clade 1 Influenza A(H5N1) Vaccine

(2015) Patricia L. Winokur et al.   JOURNAL OF INFECTIOUS DISEASES

The Avian-Origin PB1 Gene Segment Facilitated Replication and Transmissibility of the H3N2/1968 Pandemic Influenza Virus

(2015) Isabel Wendel et al.   JOURNAL OF VIROLOGY

High Preexisting Serological Antibody Levels Correlate with Diversification of the Influenza Vaccine Response

(2015) Sarah F. Andrews et al.   JOURNAL OF VIROLOGY

Phase 1 Study of Pandemic H1 DNA Vaccine in Healthy Adults

(2015) Michelle C. Crank et al.   PLoS One

The narcolepsy-pandemic influenza story: Can the truth ever be unraveled?

(2015) Miriam CJM Sturkenboom   VACCINE

Phase II trial in adults of concurrent or sequential 2009 pandemic H1N1 and 2009–2010 seasonal trivalent influenza vaccinations

(2015) Sharon E. Frey et al.   VACCINE

Cross-protection against H7N9 influenza strains using a live-attenuated H7N3 virus vaccine

(2015) Donald M. Carter et al.   VACCINE

Impact of vaccination on infection with Vietnam H5N1 high pathogenicity avian influenza virus in hens and the eggs they lay

(2015) Kateri Bertran et al.   VACCINE

Genetic Diversity of Avian Influenza A (H10N8) Virus in Live Poultry Markets and Its Association with Human Infections in China

(2015) Mingbin Liu et al.   Scientific Reports

Evaluation of MDCK Cell-Derived Influenza H7N9 Vaccine Candidates in Ferrets

(2015) Min-Yuan Chia et al.   PLoS One

A model-based economic analysis of pre-pandemic influenza vaccination cost-effectiveness

(2014) Nilimesh Halder et al.   BMC INFECTIOUS DISEASES

Phase I/II Randomized Double-Blind Study of the Safety and Immunogenicity of a Nonadjuvanted Vero Cell Culture-Derived Whole-Virus H9N2 Influenza Vaccine in Healthy Adults

(2014) Gerald Aichinger et al.   Clinical and Vaccine Immunology

Safety and Immunogenicity of a Vero Cell Culture-Derived Whole-Virus H5N1 Influenza Vaccine in Chronically Ill and Immunocompromised Patients

(2014) Maikel V. W. van der Velden et al.   Clinical and Vaccine Immunology

An H7N1 Influenza Virus Vaccine Induces Broadly Reactive Antibody Responses against H7N9 in Humans

(2014) Florian Krammer et al.   Clinical and Vaccine Immunology

Did narcolepsy occur following administration of AS03-adjuvanted A(H1N1) pandemic vaccine in Ontario, Canada? A review of post-marketing safety surveillance data

(2014) T Harris et al.   Eurosurveillance

Development of live attenuated influenza vaccines against pandemic influenza strains

(2014) Kathleen L Coelingh et al.   Expert Review of Vaccines

T-cell-mediated cross-strain protective immunity elicited by prime–boost vaccination with a live attenuated influenza vaccine

(2014) Junwei Li et al.   INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES

Immunogenicity of Avian Influenza A/Anhui/01/2005(H5N1) Vaccine With MF59 Adjuvant

(2014) Robert B. Belshe et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Influenza-Specific Antibody-Dependent Cellular Cytotoxicity: Toward a Universal Influenza Vaccine

(2014) Sinthujan Jegaskanda et al.   JOURNAL OF IMMUNOLOGY

A Live Attenuated Influenza A(H5N1) Vaccine Induces Long-Term Immunity in the Absence of a Primary Antibody Response

(2014) Kawsar R. Talaat et al.   JOURNAL OF INFECTIOUS DISEASES

A Live Attenuated Equine H3N8 Influenza Vaccine Is Highly Immunogenic and Efficacious in Mice and Ferrets

(2014) Mariana Baz et al.   JOURNAL OF VIROLOGY

Development of a High-Yield Live Attenuated H7N9 Influenza Virus Vaccine That Provides Protection against Homologous and Heterologous H7 Wild-Type Viruses in Ferrets

(2014) Z. Chen et al.   JOURNAL OF VIROLOGY

Induction of Broadly Reactive Anti-Hemagglutinin Stalk Antibodies by an H5N1 Vaccine in Humans

(2014) R. Nachbagauer et al.   JOURNAL OF VIROLOGY

Safety and immunogenicity of a modified-vaccinia-virus-Ankara-based influenza A H5N1 vaccine: a randomised, double-blind phase 1/2a clinical trial

(2014) Joost H C M Kreijtz et al.   LANCET INFECTIOUS DISEASES

Narcolepsy and influenza A(H1N1) pandemic 2009 vaccination in the United States

(2014) J. Duffy et al.   NEUROLOGY

Assessment of Human Immune Responses to H7 Avian Influenza Virus of Pandemic Potential: Results from a Placebo–Controlled, Randomized Double–Blind Phase I Study of Live Attenuated H7N3 Influenza Vaccine

(2014) Larisa Rudenko et al.   PLoS One

Antigenic Differences between AS03 Adjuvanted Influenza A (H1N1) Pandemic Vaccines: Implications for Pandemrix-Associated Narcolepsy Risk

(2014) Outi Vaarala et al.   PLoS One

Different Arms of the Adaptive Immune System Induced by a Combination Vaccine Work in Concert to Provide Enhanced Clearance of Influenza

(2014) Joanna C. A. Cobbin et al.   PLoS One

Potential antigenic explanation for atypical H1N1 infections among middle-aged adults during the 2013-2014 influenza season

(2014) S. L. Linderman et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Evolution of the H9N2 influenza genotype that facilitated the genesis of the novel H7N9 virus

(2014) Juan Pu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Cell Culture-Derived MF59-Adjuvanted Pandemic A/H7N9 Vaccine Is Immunogenic in Adults

(2014) S. A. Bart et al.   Science Translational Medicine

Complete protection against lethal challenge of novel H7N9 virus with heterologous inactivated H7 vaccine in mice

(2014) Lay Hoon Tang et al.   VACCINE

Live attenuated H7N7 influenza vaccine primes for a vigorous antibody response to inactivated H7N7 influenza vaccine

(2014) Tara M. Babu et al.   VACCINE

Challenges of selecting seasonal influenza vaccine strains for humans with diverse pre-exposure histories

(2014) Scott E Hensley   Current Opinion in Virology

Genetics, Receptor Binding Property, and Transmissibility in Mammals of Naturally Isolated H9N2 Avian Influenza Viruses

(2014) Xuyong Li et al.   PLoS Pathogens

Development of an Influenza Virologic Risk Assessment Tool

(2013) Susan C. Trock et al.   AVIAN DISEASES

Impact of Vaccines and Vaccination on Global Control of Avian Influenza

(2013) David E. Swayne   AVIAN DISEASES

Comparing influenza vaccine efficacy against mismatched and matched strains: a systematic review and meta-analysis

(2013) Andrea C Tricco et al.   BMC Medicine

Increased risk of narcolepsy in children and adults after pandemic H1N1 vaccination in France

(2013) Yves Dauvilliers et al.   BRAIN

B Cell Response and Hemagglutinin Stalk-Reactive Antibody Production in Different Age Cohorts following 2009 H1N1 Influenza Virus Vaccination

(2013) Mark Y. Sangster et al.   Clinical and Vaccine Immunology

Adjuvanted influenza vaccines

(2013) Orli Even-Or et al.   Expert Review of Vaccines

Genetic association, seasonal infections and autoimmune basis of narcolepsy

(2013) Abinav Kumar Singh et al.   JOURNAL OF AUTOIMMUNITY

Immune history shapes specificity of pandemic H1N1 influenza antibody responses

(2013) Yang Li et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Safety and Immunogenicity of a Vero Cell Culture-Derived Whole-Virus Influenza A(H5N1) Vaccine in a Pediatric Population

(2013) M. V. W. van der Velden et al.   JOURNAL OF INFECTIOUS DISEASES

Prime-Boost Interval Matters: A Randomized Phase 1 Study to Identify the Minimum Interval Necessary to Observe the H5 DNA Influenza Vaccine Priming Effect

(2013) Julie E. Ledgerwood, Kathryn Zephir, Zonghui Hu, Chih-Jen Wei, LeeJah Chang, Mary E. Enama, Cynthia S. Hendel, Sandra Sitar, Robert T. Bailer, Richard A. Koup, John R. Mascola, Gary J. Nabel, Barney S. Graham et al.   JOURNAL OF INFECTIOUS DISEASES

Risks of neurological and immune-related diseases, including narcolepsy, after vaccination with Pandemrix: a population- and registry-based cohort study with over 2 years of follow-up

(2013) I. Persson et al.   JOURNAL OF INTERNAL MEDICINE

Infection with 2009 H1N1 Influenza Virus Primes for Immunological Memory in Human Nose-Associated Lymphoid Tissue, Offering Cross-Reactive Immunity to H1N1 and Avian H5N1 Viruses

(2013) W. H. Mahallawi et al.   JOURNAL OF VIROLOGY

Identification of Critical Residues in the Hemagglutinin and Neuraminidase of Influenza Virus H1N1pdm for Vaccine Virus Replication in Embryonated Chicken Eggs

(2013) W. Wang et al.   JOURNAL OF VIROLOGY

A Single Amino Acid at the Hemagglutinin Cleavage Site Contributes to the Pathogenicity but Not the Transmission of Egyptian Highly Pathogenic H5N1 Influenza Virus in Chickens

(2013) S.-W. Yoon et al.   JOURNAL OF VIROLOGY

Safety and immunogenicity of an oral, replicating adenovirus serotype 4 vector vaccine for H5N1 influenza: a randomised, double-blind, placebo-controlled, phase 1 study

(2013) Marc Gurwith et al.   LANCET INFECTIOUS DISEASES

Cellular immune correlates of protection against symptomatic pandemic influenza

(2013) Saranya Sridhar et al.   NATURE MEDICINE

Human Infection with a Novel Avian-Origin Influenza A (H7N9) Virus

(2013) Rongbao Gao et al.   NEW ENGLAND JOURNAL OF MEDICINE

Epidemiology of Human Infections with Avian Influenza A(H7N9) Virus in China

(2013) Qun Li et al.   NEW ENGLAND JOURNAL OF MEDICINE

H7N9 Influenza Viruses Are Transmissible in Ferrets by Respiratory Droplet

(2013) Q. Zhang et al.   SCIENCE

Incidence of narcolepsy in Norwegian children and adolescents after vaccination against H1N1 influenza A

(2013) M.S. Heier et al.   SLEEP MEDICINE

H5N1 vaccines in humans

(2013) Mariana Baz et al.   VIRUS RESEARCH

Risk of narcolepsy in children and young people receiving AS03 adjuvanted pandemic A/H1N1 2009 influenza vaccine: retrospective analysis

(2013) E. Miller et al.   BMJ-British Medical Journal

Influenza virus hemagglutinin stalk-based antibodies and vaccines

(2013) Florian Krammer et al.   Current Opinion in Virology

New World Bats Harbor Diverse Influenza A Viruses

(2013) Suxiang Tong et al.   PLoS Pathogens

Surveillance for Adverse Events Following Receipt of Pandemic 2009 H1N1 Vaccine in the Post-Licensure Rapid Immunization Safety Monitoring (PRISM) System, 2009-2010

(2012) W. K. Yih et al.   AMERICAN JOURNAL OF EPIDEMIOLOGY

The Multibasic Cleavage Site in H5N1 Virus Is Critical for Systemic Spread along the Olfactory and Hematogenous Routes in Ferrets

(2012) E. J. A. Schrauwen et al.   JOURNAL OF VIROLOGY

Preexisting influenza-specific CD4+ T cells correlate with disease protection against influenza challenge in humans

(2012) Tom M Wilkinson et al.   NATURE MEDICINE

Increased Incidence and Clinical Picture of Childhood Narcolepsy following the 2009 H1N1 Pandemic Vaccination Campaign in Finland

(2012) Markku Partinen et al.   PLoS One

AS03 Adjuvanted AH1N1 Vaccine Associated with an Abrupt Increase in the Incidence of Childhood Narcolepsy in Finland

(2012) Hanna Nohynek et al.   PLoS One

A Randomized Clinical Trial of an Inactivated Avian Influenza A (H7N7) Vaccine

(2012) Robert B. Couch et al.   PLoS One

A distinct lineage of influenza A virus from bats

(2012) S. Tong et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Pandemic H1N1 influenza vaccine induces a recall response in humans that favors broadly cross-reactive memory B cells

(2012) G.-M. Li et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Airborne Transmission of Influenza A/H5N1 Virus Between Ferrets

(2012) S. Herfst et al.   SCIENCE

Pre-vaccination immunity and immune responses to a cell culture-derived whole-virus H1N1 vaccine are similar to a seasonal influenza vaccine

(2012) Hartmut J. Ehrlich et al.   VACCINE

Protective efficacy of live-attenuated influenza vaccine (multivalent, Ann Arbor strain): a literature review addressing interference

(2011) Allyn Bandell et al.   Expert Review of Vaccines

A new approach to estimate vaccine efficacy based on immunogenicity data applied to influenza vaccines administered by the intradermal or intramuscular routes

(2011) Laurent Coudeville et al.   Human vaccines & immunotherapeutics

Broadly cross-reactive antibodies dominate the human B cell response against 2009 pandemic H1N1 influenza virus infection

(2011) Jens Wrammert et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Vesicular Stomatitis Virus-Based H5N1 Avian Influenza Vaccines Induce Potent Cross-Clade Neutralizing Antibodies in Rhesus Macaques

(2011) J. A. Schwartz et al.   JOURNAL OF VIROLOGY

The Multibasic Cleavage Site of the Hemagglutinin of Highly Pathogenic A/Vietnam/1203/2004 (H5N1) Avian Influenza Virus Acts as a Virulence Factor in a Host-Specific Manner in Mammals

(2011) A. L. Suguitan et al.   JOURNAL OF VIROLOGY

DNA priming and influenza vaccine immunogenicity: two phase 1 open label randomised clinical trials

(2011) Julie E Ledgerwood et al.   LANCET INFECTIOUS DISEASES

Effect of prior vaccination with a seasonal trivalent influenza vaccine on the antibody response to the influenza pandemic H1N1 2009 vaccine: a randomized controlled trial

(2011) Shingo Uno et al.   MICROBIOLOGY AND IMMUNOLOGY

Single HA2 Mutation Increases the Infectivity and Immunogenicity of a Live Attenuated H5N1 Intranasal Influenza Vaccine Candidate Lacking NS1

(2011) Brigitte M. Krenn et al.   PLoS One

A Neutralizing Antibody Selected from Plasma Cells That Binds to Group 1 and Group 2 Influenza A Hemagglutinins

(2011) D. Corti et al.   SCIENCE

MF59 Adjuvant Enhances Diversity and Affinity of Antibody-Mediated Immune Response to Pandemic Influenza Vaccines

(2011) S. Khurana et al.   Science Translational Medicine

Live attenuated pandemic influenza vaccine: Clinical studies on A/17/California/2009/38 (H1N1) and licensing of the Russian-developed technology to WHO for pandemic influenza preparedness in developing countries

(2011) Larisa Rudenko et al.   VACCINE

Evidence for differing evolutionary dynamics of A/H5N1 viruses among countries applying or not applying avian influenza vaccination in poultry

(2011) Giovanni Cattoli et al.   VACCINE

Mutations affecting the stability of the haemagglutinin molecule impair the immunogenicity of live attenuated H3N2 intranasal influenza vaccine candidates lacking NS1

(2011) Sabine Nakowitsch et al.   VACCINE

Why Do Influenza Virus Subtypes Die Out? A Hypothesis

(2011) P. Palese et al.   mBio

Influenza virus vaccines: lessons from the 2009 H1N1 pandemic

(2011) Andrew J Broadbent et al.   Current Opinion in Virology

A Heterologous MF59-Adjuvanted H5N1 Prepandemic Influenza Booster Vaccine Induces a Robust, Cross-Reactive Immune Response in Adults and the Elderly

(2010) E. Fragapane et al.   Clinical and Vaccine Immunology

H5N1 Influenza Vaccine Formulated with AS03A Induces Strong Cross-Reactive and Polyfunctional CD4 T-Cell Responses

(2010) Philippe Moris et al.   JOURNAL OF CLINICAL IMMUNOLOGY

Successful Vaccination Strategies That Protect Aged Mice from Lethal Challenge from Influenza Virus and Heterologous Severe Acute Respiratory Syndrome Coronavirus

(2010) T. Sheahan et al.   JOURNAL OF VIROLOGY

A Live Attenuated H7N7 Candidate Vaccine Virus Induces Neutralizing Antibody That Confers Protection from Challenge in Mice, Ferrets, and Monkeys

(2010) J.-Y. Min et al.   JOURNAL OF VIROLOGY

T Cell-Mediated Protection against Lethal 2009 Pandemic H1N1 Influenza Virus Infection in a Mouse Model

(2010) H. Guo et al.   JOURNAL OF VIROLOGY

Immunogenicity and safety of a two-dose schedule of whole-virion and AS03A-adjuvanted 2009 influenza A (H1N1) vaccines: a randomised, multicentre, age-stratified, head-to-head trial

(2010) Karl G Nicholson et al.   LANCET INFECTIOUS DISEASES

Vaccinate before the next pandemic?

(2010) Klaus Stöhr   NATURE

Safety and Immunogenicity Following Administration of a Live, Attenuated Monovalent 2009 H1N1 Influenza Vaccine to Children and Adults in Two Randomized Controlled Trials

(2010) Raburn M. Mallory et al.   PLoS One

Structural Basis of Preexisting Immunity to the 2009 H1N1 Pandemic Influenza Virus

(2010) R. Xu et al.   SCIENCE

Evaluation of the cellular immune responses induced by a non-adjuvanted inactivated whole virus A/H5N1/VN/1203 pandemic influenza vaccine in humans

(2010) Brian A. Crowe et al.   VACCINE

Evaluation of Southern Hemisphere influenza vaccine recommendations

(2010) Stephanie A. Richard et al.   VACCINE

A Cell Culture (Vero)–Derived H5N1 Whole‐Virus Vaccine Induces Cross‐Reactive Memory Responses

(2009) Hartmut J. Ehrlich et al.   JOURNAL OF INFECTIOUS DISEASES

A Live Attenuated H9N2 Influenza Vaccine Is Well Tolerated and Immunogenic in Healthy Adults

(2009) Ruth A. Karron et al.   JOURNAL OF INFECTIOUS DISEASES

Newcastle Disease Virus-Vectored Vaccines Expressing the Hemagglutinin or Neuraminidase Protein of H5N1 Highly Pathogenic Avian Influenza Virus Protect against Virus Challenge in Monkeys

(2009) J. M. DiNapoli et al.   JOURNAL OF VIROLOGY

A New Genetic Vaccine Platform Based on an Adeno-Associated Virus Isolated from a Rhesus Macaque

(2009) J. Lin et al.   JOURNAL OF VIROLOGY

Origins and evolutionary genomics of the 2009 swine-origin H1N1 influenza A epidemic

(2009) Gavin J. D. Smith et al.   NATURE

Comparative Efficacy of Inactivated and Live Attenuated Influenza Vaccines

(2009) Arnold S. Monto et al.   NEW ENGLAND JOURNAL OF MEDICINE

Emergence of a Novel Swine-Origin Influenza A (H1N1) Virus in Humans

(2009)   NEW ENGLAND JOURNAL OF MEDICINE

Fast rise of broadly cross-reactive antibodies after boosting long-lived human memory B cells primed by an MF59 adjuvanted prepandemic vaccine

(2009) G. Galli et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Antibody Recognition of a Highly Conserved Influenza Virus Epitope

(2009) D. C. Ekiert et al.   SCIENCE

Safety and immunogenicity of whole-virus, alum-adjuvanted whole-virus, virosomal, and whole-virus intradermal influenza A/H9N2 vaccine formulations

(2009) Karl G. Nicholson et al.   VACCINE

A live attenuated H7N3 influenza virus vaccine is well tolerated and immunogenic in a Phase I trial in healthy adults

(2009) Kawsar R. Talaat et al.   VACCINE

Evaluation of two live attenuated cold-adapted H5N1 influenza virus vaccines in healthy adults

(2009) Ruth A. Karron et al.   VACCINE

A phase I evaluation of inactivated influenza A/H5N1 vaccine administered by the intradermal or the intramuscular route

(2009) Shital M. Patel et al.   VACCINE

Antigenic Fingerprinting of H5N1 Avian Influenza Using Convalescent Sera and Monoclonal Antibodies Reveals Potential Vaccine and Diagnostic Targets

(2009) Surender Khurana et al.   PLOS MEDICINE

Cross-Reactive Immunity to Clade 2 Strains of Influenza Virus A Subtype H5N1 Induced in Adults and Elderly Patients by Fluval, a Prototype Pandemic Influenza Virus Vaccine Derived by Reverse Genetics, Formulated with a Phosphate Adjuvant, and Directed to Clade 1 Strains

(2008) G. Fazekas et al.   Clinical and Vaccine Immunology

Safety and immunogenicity of live attenuated influenza reassortant H5 vaccine (phase I-II clinical trials)

(2008) Larisa Rudenko et al.   Influenza and Other Respiratory Viruses

Evaluation of the Safety and Immunogenicity of a Booster (Third) Dose of Inactivated Subvirion H5N1 Influenza Vaccine in Humans

(2008) Kenneth M. Zangwill et al.   JOURNAL OF INFECTIOUS DISEASES

Immune Responses of Healthy Subjects to a Single Dose of Intramuscular Inactivated Influenza A/Vietnam/1203/2004 (H5N1) Vaccine after Priming with an Antigenic Variant

(2008) Nega Ali Goji et al.   JOURNAL OF INFECTIOUS DISEASES

Antibody Persistence after 2‐Dose Priming and Booster Response to a Third Dose of an Inactivated, Adjuvanted, Whole‐Virion H5N1 Vaccine

(2008) Jiang‐Tao Lin et al.   JOURNAL OF INFECTIOUS DISEASES

Using Surveillance to Evaluate Influenza Vaccine Effectiveness

(2008) Lisa A. Jackson   JOURNAL OF INFECTIOUS DISEASES

Cross-Recognition of Avian H5N1 Influenza Virus by Human Cytotoxic T-Lymphocyte Populations Directed to Human Influenza A Virus

(2008) J. H. C. M. Kreijtz et al.   JOURNAL OF VIROLOGY

Evaluation of Live Attenuated Influenza A Virus H6 Vaccines in Mice and Ferrets

(2008) Z. Chen et al.   JOURNAL OF VIROLOGY

Stockpiling prepandemic influenza vaccines: a new cornerstone of pandemic preparedness plans

(2008) Lance C Jennings et al.   LANCET INFECTIOUS DISEASES

Antigenically Distinct MF59-Adjuvanted Vaccine to Boost Immunity to H5N1

(2008) Iain Stephenson et al.   NEW ENGLAND JOURNAL OF MEDICINE

Update on Avian Influenza A (H5N1) Virus Infection in Humans

(2008)   NEW ENGLAND JOURNAL OF MEDICINE

A Clinical Trial of a Whole-Virus H5N1 Vaccine Derived from Cell Culture

(2008) Hartmut J. Ehrlich et al.   NEW ENGLAND JOURNAL OF MEDICINE

Cross-Protection against Lethal H5N1 Challenge in Ferrets with an Adjuvanted Pandemic Influenza Vaccine

(2008) Benoît Baras et al.   PLoS One

Safety and immunogenicity of a prototype adjuvanted inactivated split-virus influenza A (H5N1) vaccine in infants and children

(2008) Terry Nolan et al.   VACCINE