- Home
- Publications
- Publication Search
- Publication Details
Title
A proteome-wide atlas of lysine-reactive chemistry
Authors
Keywords
-
Journal
Nature Chemistry
Volume -, Issue -, Pages -
Publisher
Springer Science and Business Media LLC
Online
2021-09-10
DOI
10.1038/s41557-021-00765-4
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- 2H-Azirine-Based Reagents for Chemoselective Bioconjugation at Carboxyl Residues Inside Live Cells
- (2020) Nan Ma et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Light-Activatable, 2,5-Disubstituted Tetrazoles for the Proteome-wide Profiling of Aspartates and Glutamates in Living Bacteria
- (2020) Kathrin Bach et al. ACS Central Science
- An Activity-Guided Map of Electrophile-Cysteine Interactions in Primary Human T Cells
- (2020) Ekaterina V. Vinogradova et al. CELL
- Lysine-Targeted Inhibitors and Chemoproteomic Probes
- (2019) Adolfo Cuesta et al. Annual Review of Biochemistry
- Electrophilic PROTACs that degrade nuclear proteins by engaging DCAF16
- (2019) Xiaoyu Zhang et al. Nature Chemical Biology
- Global targeting of functional tyrosines using sulfur-triazole exchange chemistry
- (2019) Heung Sik Hahm et al. Nature Chemical Biology
- The Cysteinome of Protein Kinases as a Target in Drug Development
- (2018) Apirat Chaikuad et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Rapid labelling and covalent inhibition of intracellular native proteins using ligand-directed N-acyl-N-alkyl sulfonamide
- (2018) Tomonori Tamura et al. Nature Communications
- Protein-RNA Interactions: Structural Characteristics and Hotspot Amino Acids
- (2018) Dennis M. Krüger et al. RNA
- Broad-Spectrum Kinase Profiling in Live Cells with Lysine-Targeted Sulfonyl Fluoride Probes
- (2017) Qian Zhao et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- “Inverse Drug Discovery” Strategy To Identify Proteins That Are Targeted by Latent Electrophiles As Exemplified by Aryl Fluorosulfates
- (2017) David E. Mortenson et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Global profiling of lysine reactivity and ligandability in the human proteome
- (2017) Stephan M. Hacker et al. Nature Chemistry
- Redox-based reagents for chemoselective methionine bioconjugation
- (2017) Shixian Lin et al. SCIENCE
- Discovery of GBT440, an Orally Bioavailable R-State Stabilizer of Sickle Cell Hemoglobin
- (2017) Brian Metcalf et al. ACS Medicinal Chemistry Letters
- The Ku70 80 ring in Non-Homologous End-Joining easy to slip on hard to remove
- (2016) Guido Keijzers Frontiers in Bioscience-Landmark
- Proteome-wide covalent ligand discovery in native biological systems
- (2016) Keriann M. Backus et al. NATURE
- Inhibition of Mcl-1 through covalent modification of a noncatalytic lysine side chain
- (2016) Gizem Akçay et al. Nature Chemical Biology
- Colorimetric and fluorescence probe for the detection of nano-molar lysine in aqueous medium
- (2016) Susanta Adhikari et al. ORGANIC & BIOMOLECULAR CHEMISTRY
- Traceless and Chemoselective Amine Bioconjugation via Phthalimidine Formation in Native Protein Modification
- (2016) Chun Ling Tung et al. ORGANIC LETTERS
- Advancing Biological Understanding and Therapeutics Discovery with Small-Molecule Probes
- (2015) Stuart L. Schreiber et al. CELL
- DataWarrior: An Open-Source Program For Chemistry Aware Data Visualization And Analysis
- (2015) Thomas Sander et al. Journal of Chemical Information and Modeling
- Genomic variations of the mevalonate pathway in porokeratosis
- (2015) Zhenghua Zhang et al. eLife
- A Novel Ribosomopathy Caused by Dysfunction of RPL10 Disrupts Neurodevelopment and Causes X-Linked Microcephaly in Humans
- (2014) S. S. Brooks et al. GENETICS
- Remodeling Natural Products: Chemistry and Serine Hydrolase Activity of a Rocaglate-Derived β-Lactone
- (2014) Neil J. Lajkiewicz et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Investigating the Proteome Reactivity and Selectivity of Aryl Halides
- (2014) D. Alexander Shannon et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Interferon-Induced Ifit Proteins: Their Role in Viral Pathogenesis
- (2014) Volker Fensterl et al. JOURNAL OF VIROLOGY
- Preclinical and clinical efficacy of XPO1/CRM1 inhibition by the karyopherin inhibitor KPT-330 in Ph+ leukemias
- (2013) C. J. Walker et al. BLOOD
- Stilbene Vinyl Sulfonamides as Fluorogenic Sensors of and Traceless Covalent Kinetic Stabilizers of Transthyretin That Prevent Amyloidogenesis
- (2013) Eul Hyun Suh et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- K-Ras(G12C) inhibitors allosterically control GTP affinity and effector interactions
- (2013) Jonathan M. Ostrem et al. NATURE
- Structural basis for viral 5′-PPP-RNA recognition by human IFIT proteins
- (2013) Yazan M. Abbas et al. NATURE
- A chemoproteomic platform to quantitatively map targets of lipid-derived electrophiles
- (2013) Chu Wang et al. NATURE METHODS
- Fragment-Based Approaches in Drug Discovery and Chemical Biology
- (2012) Duncan E. Scott et al. BIOCHEMISTRY
- The pharmacological landscape and therapeutic potential of serine hydrolases
- (2012) Daniel A. Bachovchin et al. NATURE REVIEWS DRUG DISCOVERY
- Remodelling of the natural product fumagillol employing a reaction discovery approach
- (2011) Bradley R. Balthaser et al. Nature Chemistry
- Impact of high-throughput screening in biomedical research
- (2011) Ricardo Macarron et al. NATURE REVIEWS DRUG DISCOVERY
- Strategies for discovering and derisking covalent, irreversible enzyme inhibitors
- (2010) Douglas S Johnson et al. Future Medicinal Chemistry
- LPS Impairs Phospholipid Synthesis by Triggering β-Transducin Repeat-containing Protein (β-TrCP)-mediated Polyubiquitination and Degradation of the Surfactant Enzyme Acyl-CoA:Lysophosphatidylcholine Acyltransferase I (LPCAT1)
- (2010) Chunbin Zou et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Quantitative reactivity profiling predicts functional cysteines in proteomes
- (2010) Eranthie Weerapana et al. NATURE
- Chemoselective small molecules that covalently modify one lysine in a non-enzyme protein in plasma
- (2010) Sungwook Choi et al. Nature Chemical Biology
- Covalent Modification of Lysine Residues by Allyl Isothiocyanate in Physiological Conditions: Plausible Transformation of Isothiocyanate from Thiol to Amine
- (2009) Toshiyuki Nakamura et al. CHEMICAL RESEARCH IN TOXICOLOGY
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started