Interferon-Induced Ifit Proteins: Their Role in Viral Pathogenesis

IFIT1: A dual sensor and effector molecule that detects non-2′-O methylated viral RNA and inhibits its translation

(2014) Michael S. Diamond   CYTOKINE & GROWTH FACTOR REVIEWS

Sendai Virus Pathogenesis in Mice Is Prevented by Ifit2 and Exacerbated by Interferon

(2014) J. L. Wetzel et al.   JOURNAL OF VIROLOGY

Interferon-Induced Protein Ifit2 Protects Mice from Infection of the Peripheral Nervous System by Vesicular Stomatitis Virus

(2014) V. Fensterl et al.   JOURNAL OF VIROLOGY

Long-Distance Interferon Signaling within the Brain Blocks Virus Spread

(2014) A. N. van den Pol et al.   JOURNAL OF VIROLOGY

Attenuation and Restoration of Severe Acute Respiratory Syndrome Coronavirus Mutant Lacking 2'-O-Methyltransferase Activity

(2014) V. D. Menachery et al.   JOURNAL OF VIROLOGY

A Viral RNA Structural Element Alters Host Recognition of Nonself RNA

(2014) J. L. Hyde et al.   SCIENCE

Interferon-stimulated genes: roles in viral pathogenesis

(2014) John W Schoggins   Current Opinion in Virology

IFITs: Emerging Roles as Key Anti-Viral Proteins

(2014) Gregory I. Vladimer et al.   Frontiers in Immunology

IFIT5 potentiates anti-viral response through enhancing innate immune signaling pathways

(2013) B. Zhang et al.   ACTA BIOCHIMICA ET BIOPHYSICA SINICA

Ifit2 Deficiency Results in Uncontrolled Neurotropic Coronavirus Replication and Enhanced Encephalitis via Impaired Alpha/Beta Interferon Induction in Macrophages

(2013) N. B. Butchi et al.   JOURNAL OF VIROLOGY

A Role for Ifit2 in Restricting West Nile Virus Infection in the Brain

(2013) H. Cho et al.   JOURNAL OF VIROLOGY

Ifit1 Inhibits Japanese Encephalitis Virus Replication through Binding to 5' Capped 2'-O Unmethylated RNA

(2013) T. Kimura et al.   JOURNAL OF VIROLOGY

Adenovirus Detection by the cGAS/STING/TBK1 DNA Sensing Cascade

(2013) E. Lam et al.   JOURNAL OF VIROLOGY

Structural basis for viral 5′-PPP-RNA recognition by human IFIT proteins

(2013) Yazan M. Abbas et al.   NATURE

Differential innate immune response programs in neuronal subtypes determine susceptibility to infection in the brain by positive-stranded RNA viruses

(2013) Hyelim Cho et al.   NATURE MEDICINE

Inhibition of translation by IFIT family members is determined by their ability to interact selectively with the 5'-terminal regions of cap0-, cap1- and 5'ppp- mRNAs

(2013) P. Kumar et al.   NUCLEIC ACIDS RESEARCH

PNAS Plus: From the Cover: IFI16 senses DNA forms of the lentiviral replication cycle and controls HIV-1 replication

(2013) M. R. Jakobsen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Sequestration by IFIT1 Impairs Translation of 2′O-unmethylated Capped RNA

(2013) Matthias Habjan et al.   PLoS Pathogens

Crystal structure of ISG54 reveals a novel RNA binding structure and potential functional mechanisms

(2012) Zhenlin Yang et al.   CELL RESEARCH

ISG56/IFIT1 is primarily responsible for interferon-induced changes to patterns of parainfluenza virus type 5 transcription and protein synthesis

(2012) J. Andrejeva et al.   JOURNAL OF GENERAL VIROLOGY

Distinct and overlapping genomic profiles and antiviral effects of Interferon-λ and -α on HCV-infected and noninfected hepatoma cells

(2012) A. Kohli et al.   JOURNAL OF VIRAL HEPATITIS

Identification of Cytoplasmic Capping Targets Reveals a Role for Cap Homeostasis in Translation and mRNA Stability

(2012) Chandrama Mukherjee et al.   Cell Reports

Interferon-Induced Ifit2/ISG54 Protects Mice from Lethal VSV Neuropathogenesis

(2012) Volker Fensterl et al.   PLoS Pathogens

2′-O Methylation of the Viral mRNA Cap by West Nile Virus Evades Ifit1-Dependent and -Independent Mechanisms of Host Restriction In Vivo

(2012) Kristy J. Szretter et al.   PLoS Pathogens

Genetic Variants of Interferon-Stimulated Genes and IL-28B as Host Prognostic Factors of Response to Combination Treatment for Chronic Hepatitis C

(2011) R Lopez-Rodriguez et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

IFN-Induced TPR Protein IFIT3 Potentiates Antiviral Signaling by Bridging MAVS and TBK1

(2011) X.-Y. Liu et al.   JOURNAL OF IMMUNOLOGY

ISG56 and IFITM1 Proteins Inhibit Hepatitis C Virus Replication

(2011) A. Raychoudhuri et al.   JOURNAL OF VIROLOGY

Interplay between Innate Immunity and Negative-Strand RNA Viruses: towards a Rational Model

(2011) D. Gerlier et al.   MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS

Ribose 2′-O-methylation provides a molecular signature for the distinction of self and non-self mRNA dependent on the RNA sensor Mda5

(2011) Roland Züst et al.   NATURE IMMUNOLOGY

IFIT1 is an antiviral protein that recognizes 5′-triphosphate RNA

(2011) Andreas Pichlmair et al.   NATURE IMMUNOLOGY

Interferon-stimulated genes and their antiviral effector functions

(2011) John W Schoggins et al.   Current Opinion in Virology

The Interferon Stimulated Gene 54 Promotes Apoptosis

(2010) Marcin Stawowczyk et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The ISG56/IFIT1 Gene Family

(2010) Volker Fensterl et al.   JOURNAL OF INTERFERON AND CYTOKINE RESEARCH

Subcapsular sinus macrophages prevent CNS invasion on peripheral infection with a neurotropic virus

(2010) Matteo Iannacone et al.   NATURE

2′-O methylation of the viral mRNA cap evades host restriction by IFIT family members

(2010) Stephane Daffis et al.   NATURE

Interferons and viral infections

(2009) Volker Fensterl et al.   BIOFACTORS

ISG56 is a negative-feedback regulator of virus-triggered signaling and cellular antiviral response

(2009) Y. Li et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Interferon-inducible protein, P56, inhibits HPV DNA replication by binding to the viral protein E1

(2008) Fulvia Terenzi et al.   EMBO JOURNAL