Redox-based reagents for chemoselective methionine bioconjugation

SF2312 is a natural phosphonate inhibitor of enolase

(2016) Paul G Leonard et al.   Nature Chemical Biology

Oxidation increases the strength of the methionine-aromatic interaction

(2016) Andrew K Lewis et al.   Nature Chemical Biology

Expanding the chemical toolbox for the synthesis of large and uniquely modified proteins

(2016) Somasekhar Bondalapati et al.   Nature Chemistry

A chemical biology route to site-specific authentic protein modifications

(2016) A. Yang et al.   SCIENCE

Posttranslational mutagenesis: A chemical strategy for exploring protein side-chain diversity

(2016) T. H. Wright et al.   SCIENCE

Chemical Approaches to Discovery and Study of Sources and Targets of Hydrogen Peroxide Redox Signaling Through NADPH Oxidase Proteins

(2015) Thomas F. Brewer et al.   Annual Review of Biochemistry

Regulation of Protein Function by Reversible Methionine Oxidation and the Role of Selenoprotein MsrB1

(2015) Alaattin Kaya et al.   ANTIOXIDANTS & REDOX SIGNALING

Site-Specific Antibody–Drug Conjugates: The Nexus of Bioorthogonal Chemistry, Protein Engineering, and Drug Development

(2015) Paresh Agarwal et al.   BIOCONJUGATE CHEMISTRY

Advances in Chemical Protein Modification

(2015) Omar Boutureira et al.   CHEMICAL REVIEWS

Developments and recent advancements in the field of endogenous amino acid selective bond forming reactions for bioconjugation

(2015) Oleksandr Koniev et al.   CHEMICAL SOCIETY REVIEWS

Sulfur imidations: access to sulfimides and sulfoximines

(2015) Vincent Bizet et al.   CHEMICAL SOCIETY REVIEWS

Covalent protein modification: the current landscape of residue-specific electrophiles

(2015) D Alexander Shannon et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

A High Through-put Platform for Recombinant Antibodies to Folded Proteins

(2015) Michael Hornsby et al.   MOLECULAR & CELLULAR PROTEOMICS

Organometallic palladium reagents for cysteine bioconjugation

(2015) Ekaterina V. Vinogradova et al.   NATURE

Isotope-targeted glycoproteomics (IsoTaG): a mass-independent platform for intact N- and O-glycopeptide discovery and analysis

(2015) Christina M Woo et al.   NATURE METHODS

Activity-Based Profiling of Proteases

(2014) Laura E. Sanman et al.   Annual Review of Biochemistry

Sulfur as a Signaling Nutrient Through Hydrogen Sulfide

(2014) Omer Kabil et al.   Annual Review of Nutrition

Advances in the Chemistry of Oxaziridines

(2014) Kevin S. Williamson et al.   CHEMICAL REVIEWS

Click Chemistry in Complex Mixtures: Bioorthogonal Bioconjugation

(2014) Craig S. McKay et al.   CHEMISTRY & BIOLOGY

Selective chemical protein modification

(2014) Christopher D. Spicer et al.   Nature Communications

A tool kit for rapid cloning and expression of recombinant antibodies

(2014) Tihomir S. Dodev et al.   Scientific Reports

Selection of chromosomal DNA libraries using a multiplex CRISPR system

(2014) Owen W Ryan et al.   eLife

Small-Molecule-Based Protein-Labeling Technology in Live Cell Studies: Probe-Design Concepts and Applications

(2013) Shin Mizukami et al.   ACCOUNTS OF CHEMICAL RESEARCH

Reversible chemoselective tagging and functionalization of methionine containing peptides

(2013) Jessica R. Kramer et al.   CHEMICAL COMMUNICATIONS

Cysteine-Mediated Redox Signaling: Chemistry, Biology, and Tools for Discovery

(2013) Candice E. Paulsen et al.   CHEMICAL REVIEWS

Developing Irreversible Inhibitors of the Protein Kinase Cysteinome

(2013) Qingsong Liu et al.   CHEMISTRY & BIOLOGY

Technological advances in site-directed spin labeling of proteins

(2013) Wayne L Hubbell et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

MsrB1 and MICALs Regulate Actin Assembly and Macrophage Function via Reversible Stereoselective Methionine Oxidation

(2013) Byung Cheon Lee et al.   MOLECULAR CELL

K-Ras(G12C) inhibitors allosterically control GTP affinity and effector interactions

(2013) Jonathan M. Ostrem et al.   NATURE

Preparation of Multifunctional and Multireactive Polypeptides via Methionine Alkylation

(2012) Jessica R. Kramer et al.   BIOMACROMOLECULES

Reversible targeting of noncatalytic cysteines with chemically tuned electrophiles

(2012) Iana M Serafimova et al.   Nature Chemical Biology

Exploring Protein Lipidation with Chemical Biology

(2011) Howard C. Hang et al.   CHEMICAL REVIEWS

Fast, scalable generation of high-quality protein multiple sequence alignments using Clustal Omega

(2011) F. Sievers et al.   Molecular Systems Biology

Choosing an effective protein bioconjugation strategy

(2011) Nicholas Stephanopoulos et al.   Nature Chemical Biology

Chemistry and biology of reactive oxygen species in signaling or stress responses

(2011) Bryan C Dickinson et al.   Nature Chemical Biology

Direct Redox Regulation of F-Actin Assembly and Disassembly by Mical

(2011) R.-J. Hung et al.   SCIENCE

Residue-specific incorporation of non-canonical amino acids into proteins: recent developments and applications

(2010) Jeremiah A Johnson et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Cleavable Biotin Probes for Labeling of Biomolecules via Azide−Alkyne Cycloaddition

(2010) Janek Szychowski et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Quantitative reactivity profiling predicts functional cysteines in proteomes

(2010) Eranthie Weerapana et al.   NATURE

Understanding the Warburg Effect: The Metabolic Requirements of Cell Proliferation

(2009) M. G. Vander Heiden et al.   SCIENCE

A Dynamic Pathway for Calcium-Independent Activation of CaMKII by Methionine Oxidation

(2008) Jeffrey R. Erickson et al.   CELL

Site-specific conjugation of a cytotoxic drug to an antibody improves the therapeutic index

(2008) Jagath R Junutula et al.   NATURE BIOTECHNOLOGY

What’s Driving False Discovery Rates?

(2007) David L. Tabb   JOURNAL OF PROTEOME RESEARCH