Article
Engineering, Chemical
Wan-Tzu Yen, Ke-Hsuan Wang, Masaaki Yoshida, Murugesan Balamurugan, Takeshi Kawai, Shanmugamathan Venkatesan, Yuh-Lang Lee
Summary: In this study, dodecylamine is used as a model molecule to investigate its self-assembly behavior on an Au surface. The results show weak interaction and slow adsorption of DDA with the gold surface, with molecules arranged in a flat-lying orientation.
JOURNAL OF THE TAIWAN INSTITUTE OF CHEMICAL ENGINEERS
(2021)
Article
Chemistry, Multidisciplinary
Alex K. Chew, Bradley C. Dallin, Reid C. Van Lehn
Summary: The hydrophobicity of monolayer-protected gold nanoparticles is primarily determined by ligand end group chemistry for large nanoparticles, while interactions between long alkanethiol ligands lead to spatial variations in hydrophobicity for small nanoparticles. However, changing ligand structure, ligand chemistry, and gold core size can modulate nanoparticle hydrophobicity, emphasizing the need to consider both physical and chemical properties when predicting interactions with biomolecules.
Article
Multidisciplinary Sciences
Alex Inayeh, Ryan R. K. Groome, Ishwar Singh, Alex J. Veinot, Felipe Crasto de Lima, Roberto H. Miwa, Cathleen M. Crudden, Alastair B. McLean
Summary: N-heterocyclic carbenes (NHCs) have emerged as a promising alternative to sulfur-based ligands for self-assembly on gold surfaces, but there are still many unanswered questions about their behavior on surfaces. This study examines fundamental questions such as NHC orientation, mobility, and self-assembly by analyzing NHC overlayers on Au(111).
NATURE COMMUNICATIONS
(2021)
Article
Multidisciplinary Sciences
Liping Song, Ben Bin Xu, Qian Cheng, Xiaoyuan Wang, Xiaoning Luo, Xue Chen, Tao Chen, Youju Huang
Summary: The wetting empowered interfacial self-assembly technique allows for rapid and efficient fabrication of thin films with universal applicability on various materials, achieving large-area coverage of monolayers. This method has significant implications in advancing thin film technology and can be applied in a user-friendly and cost-effective manner for various applications.
Article
Chemistry, Multidisciplinary
Alessandro Marchetti, Alessandro Gori, Anna Maria Ferretti, Daniel Arenas Esteban, Sara Bals, Claudia Pigliacelli, Pierangelo Metrangolo
Summary: Finite 3D structures with controlled morphology can be achieved in the out-of-equilibrium self-assembly of Au NPs using a spherical peptide-gold superstructure (PAuSS) as a template, resulting in a transient 3D-branched Au-nanoshell (BAuNS) stabilized by sodium dodecyl sulphate (SDS). The BAuNS dismantles and regresses to PAuSS through equilibrium of SDS concentration gradient over time in the sample solution, causing NP disassembly. The assembly and disassembly of BAuNS promote temporary interparticle plasmonic coupling, enabling reversible and tunable changes in their plasmonic properties, which is highly desirable for the development of optoelectronic nanodevices.
Article
Nanoscience & Nanotechnology
Mizuki Matsukawa, Ke-Hsuan Wang, Yoshiro Imura, Takeshi Kawai
Summary: This study developed a method for fabricating flexible and transparent Au nanosheets conductive electrodes using UV irradiation, and demonstrated the reusability of Au nanoparticle dispersions in preparing transparent flexible electrodes.
ACS APPLIED NANO MATERIALS
(2021)
Article
Chemistry, Multidisciplinary
Cristian Gabellini, Maria Sologan, Elena Pellizzoni, Domenico Marson, Mario Daka, Paola Franchi, Luca Bignardi, Stefano Franchi, Zbysek Posel, Alessandro Baraldi, Paolo Pengo, Marco Lucarini, Lucia Pasquato, Paola Posocco
Summary: Organic-inorganic nanomaterials are versatile platforms with wide application areas. We introduce a general methodology to identify and classify local molecular environments in self-assembled monolayer-protected gold nanoparticles (SAM-AuNPs), and explore factors influencing the number and nature of these environments. This work is important for understanding and designing hybrid nanoconstructs.
Article
Chemistry, Multidisciplinary
Alex K. Chew, Joel A. Pedersen, Reid C. Van Lehn
Summary: This study demonstrates the use of molecular dynamics simulations to predict the properties and cellular uptake of gold nanoparticles, and identifies important descriptors and atomic-level mechanisms, providing guidance for the design of monolayer-protected gold nanoparticles for biological applications.
Article
Chemistry, Physical
Navathej Preetha Genesh, Daling Cui, Dominik Dettmann, Oliver MacLean, Tarnjit Kaur Johal, Andrey V. Lunchev, Andrew C. Grimsdale, Federico Rosei
Summary: The precise control of molecular self-assembly on surfaces provides opportunities for complex nanostructure creation. Selective patterning using molecular interactions at the solid-liquid interface was observed in the self-assembly of 1,3,5-tris(4-methoxyphenyl)benzene (TMPB) molecules on the Au(111) surface. Resulting from higher adsorption energy, TMPB molecules preferred to assemble in the face-centered cubic (FCC) regions of Au(111). The coverage of TMPB molecules increased with solution concentration, leading to a full monolayer, and induced the lifting of the herringbone reconstruction at higher concentrations.
JOURNAL OF PHYSICAL CHEMISTRY LETTERS
(2023)
Article
Nanoscience & Nanotechnology
Lixiang Xing, Yujiao Xiahou, Xiang Zhang, Wei Du, Panpan Zhang, Haibing Xia
Summary: In this study, core-shell Au-5.5@Ag-m nanoparticles with controlled thicknesses of Ag shells were successfully synthesized. High-quality monolayer films of hexagonal close-packed Au@Ag nanoparticles were fabricated using self-assembly methods. These films exhibited uniform surface-enhanced Raman scattering signals when transferred onto PDMS substrates. They showed high sensitivity and quantitative detection ability for crystal violet and 4-aminothiophenol.
ACS APPLIED MATERIALS & INTERFACES
(2022)
Article
Chemistry, Multidisciplinary
Rishi Ram Mahato, Sakshi Juneja, Subhabrata Maiti
Summary: This study compares the catalytic effects of self-assembled monolayer (SAM)-protected cationic nanoparticles and cationic surfactants in an organic reaction. The results show that the nanoparticles exhibit higher activity at lower cationic head group concentrations compared to surfactants of similar hydrophobicity. The study also demonstrates the selectivity of nucleotides in the reaction and the enhancement of catalysis through enzyme-mediated nucleotide hydrolysis. These findings highlight the superiority of SAM-protected nanoparticles as catalysts and their potential applications in selective recognition and eco-friendly catalysis.
CHEMISTRY-AN ASIAN JOURNAL
(2023)
Article
Chemistry, Physical
Jose M. Abad, Marcos Pita, Antonio L. De Lacey
Summary: Monolayer-Protected Gold Clusters (AuMPCs) have attracted great interest as nanoscale capacitors in aqueous media for various nanobiotechnological applications. However, achieving subattofarad double-layer capacitance and single-electron charging has been challenging. In this study, we successfully synthesized Thioctic Acid Monolayer-Protected Au Clusters (TA-AuMPCs) that exhibited electrochemical single electron quantized capacitance charging in both organic and aqueous solutions. The functional carboxylic groups present in TA-AuMPCs provide a simple strategy for interfacing nanoparticles with biomolecules for biological electron transfer reactions.
JOURNAL OF PHYSICAL CHEMISTRY LETTERS
(2023)
Article
Physics, Applied
Weien Lai, Qing Zhu, Gen Liu, Guanghua Shi, Yichen Gan, Abbas Amini, Chun Cheng
Summary: The study proposes a broadband and large-depth THz modulator based on silicon/silver nanoparticle arrays, which can achieve broadband modulation within the frequency range of 0.2-2.0 THz with a large modulation depth of 91.2% under a NIR light intensity of 1.77 W cm(-2).
JOURNAL OF PHYSICS D-APPLIED PHYSICS
(2022)
Article
Chemistry, Multidisciplinary
Yazi Wang, Hongyan Li, Jiao Chu, Yifan Xia, Shunsheng Ye, Fan Yang, Wei Cao, Jun-Yi Ge, Yifei Xu, Meifang Zhu, Hongyu Pan, Zhihong Nie
Summary: By combining chemical patterning and magnetic manipulation, we demonstrate the selective assembly of magnetic nanoellipsoids into large-area precisely positioned, orientationally controlled arrays. This approach is simple to implement and can generate high yield of precisely engineered arrays of nanoparticles.
Article
Chemistry, Physical
Caikun Cheng, Jingjing Wei, Zhijie Yang
Summary: The addition of trace amounts of water molecules in nonpolar solvents can drive the assembly of inorganic nanocrystals into superstructures with increasing complexities. By tuning the amount of water, nanocrystals can be directed to assemble into different superstructures, showcasing the potential for engineering nanocrystal assembly pathways.
JOURNAL OF PHYSICAL CHEMISTRY C
(2021)
Article
Chemistry, Multidisciplinary
Sandra Claveau, Emilie Nehlig, Sebastien Garcia-Argote, Sophie Feuillastre, Gregory Pieters, Hugues A. Girard, Jean-Charles Arnault, Francois Treussart, Jean-Remi Bertrand
Article
Chemistry, Multidisciplinary
Marion Daniel-Bertrand, Sebastien Garcia-Argote, Alberto Palazzolo, Irene Mustieles Marin, Pier-Francesco Fazzini, Simon Tricard, Bruno Chaudret, Volker Derdau, Sophie Feuillastre, Gregory Pieters
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2020)
Review
Chemistry, Multidisciplinary
Marco Lepron, Marion Daniel-Bertrand, Gabriel Mencia, Bruno Chaudret, Sophie Feuillastre, Gregory Pieters
Summary: Hydrogen isotope exchange (HIE) reactions have shown significant progress in recent years, playing a crucial role in the synthesis of tritium and deuterium-labeled compounds, as well as in improving the ADME properties of bioactive molecules. Nanocatalysis has been demonstrated as an effective tool for regio- and chemoselective labeling of complex molecules, bridging the gap between homogeneous and heterogeneous catalysis.
ACCOUNTS OF CHEMICAL RESEARCH
(2021)
Review
Chemistry, Multidisciplinary
Lucas Frederic, Alaric Desmarchelier, Ludovic Favereau, Gregory Pieters
Summary: The development of efficient CP-Organic Light-Emitting Diodes (CP-OLEDs) through the design of fluorophores merging circularly polarized (CP) luminescence and thermally activated delayed fluorescence (TADF) properties is a promising direction. This progress report provides an overview of molecular designs explored to obtain CP-TADF properties, their performance as chiral emitters in CP-OLEDs, and the future challenges in this emerging research field.
ADVANCED FUNCTIONAL MATERIALS
(2021)
Article
Chemistry, Multidisciplinary
Aurelie Mace, Khaoula Hamrouni, Etienne S. Gauthier, Marion Jean, Nicolas Vanthuyne, Lucas Frederic, Gregory Pieters, Elsa Caytan, Thierry Roisnel, Faouzi Aloui, Monika Srebro-Hooper, Bertrand Carboni, Fabienne Berree, Jeanne Crassous
Summary: This study successfully synthesized a series of mono- and di-boranil-substituted helicenes, and investigated their chiroptical properties using various methods; enantiomeric resolution was achieved through different experimental techniques, followed by structural analysis.
CHEMISTRY-A EUROPEAN JOURNAL
(2021)
Article
Chemistry, Multidisciplinary
Zijie Qiu, Cheng-Wei Ju, Lucas Frederic, Yunbin Hu, Dieter Schollmeyer, Gregory Pieters, Klaus Muellen, Akimitsu Narita
Summary: In this study, pi-Extended [7]helicene and pi-Extended [9]helicene were successfully synthesized with improved photophysical properties and high circularly polarized luminescence brightness. The research also revealed that a small variation in helical length can cause an increase in dissymmetry factors.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
(2021)
Article
Pharmacology & Pharmacy
Eleonore Coppens, Didier Desmaele, Timothee Naret, Sebastien Garcia-Argote, Sophie Feuillastre, Gregory Pieters, Catherine Cailleau, Jean-Louis Paul, Bastien Prost, Audrey Solgadi, Jean-Philippe Michel, Magali Noiray, Patrick Couvreur, Simona Mura
Summary: The study showed that inducing drug insertion into lipoproteins through chemical modification is a simple approach to achieve lipoprotein-mediated drug delivery. While the lipid moiety plays a key role in the interaction between the drug and lipoproteins, the overall physicochemical features of the nanoparticles must also be carefully considered.
INTERNATIONAL JOURNAL OF PHARMACEUTICS
(2021)
Article
Chemistry, Multidisciplinary
Patthira Sumsalee, Laura Abella, Sitthichok Kasemthaveechok, Nicolas Vanthuyne, Marie Cordier, Gregory Pieters, Jochen Autschbach, Jeanne Crassous, Ludovic Favereau
Summary: A new approach using luminescent exciplexes based on a chiral electron donor and achiral acceptors has been reported for designing circularly polarized and thermally activated delayed fluorescence emitters. High CP luminescence values were achieved with a CPL signal inversion, showing promise for multi-color CP-TADF emitters.
CHEMISTRY-A EUROPEAN JOURNAL
(2021)
Article
Materials Science, Multidisciplinary
Max Coehlo, Gilles Clavier, Gregory Pieters
Summary: This study describes a novel molecular design that allows the combination of circularly polarized luminescence (CPL) and excited state intramolecular proton transfer (ESIPT) fluorescence. By tethering two ESIPT fluorophores via a readily accessible trans-1,2-diaminocyclohexane scaffold, chiroptical activity can be induced, leading to the synthesis of CPL-active molecules with a large Stokes shift and rare examples of CPL-active purely organic dual-emission materials in a single step and three steps, respectively.
ADVANCED OPTICAL MATERIALS
(2022)
Article
Chemistry, Medicinal
Heloise Cahuzac, Antoine Sallustrau, Carole Malgorn, Fabrice Beau, Peggy Barbe, Victor Babin, Steven Dubois, Alberto Palazzolo, Robert Thai, Isabelle Correia, Ki Baek Lee, Sebastien Garcia-Argote, Olivier Lequin, Mathilde Keck, Herve Nozach, Sophie Feuillastre, Xin Ge, Gregory Pieters, Davide Audisio, Laurent Devel
Summary: This article presents a bioanalytical strategy based on dual radiolabeling and ex vivo digital imaging for accurate determination of the plasma and tissue profiles of protein-drug conjugates. The strategy involves enzymatic and chemical reactions to obtain dual-labeled anti-MMP-14 Fabs conjugated to monomethyl auristatin E, allowing for simultaneous monitoring and accurate quantification of the components during circulation phase and accumulation in different organs.
JOURNAL OF MEDICINAL CHEMISTRY
(2022)
Article
Chemistry, Multidisciplinary
Etienne Levernier, Kevin Tatoueix, Sebastien Garcia-Argote, Viktor Pfeifer, Ralf Kiesling, Edmond Gravel, Sophie Feuillastre, Gregory Pieters
Summary: This report describes a simple labeling process using in situ generated Rh nanopartides to label common substructures in drugs. The size of the observed nanopartides is independent of the substrate used and is consistently distributed. The method has been successfully applied to the one-step synthesis of deuterated pharmaceuticals and tritiated drug analogues with high molar activities.
Article
Chemistry, Multidisciplinary
Expedite Yen-Pon, Floris Buttard, Lucas Frederic, Pierre Thuery, Frederic Taran, Gregory Pieters, Pier Alexandre Champagne, Davide Audisio
Summary: A regioselective access to heterohelicenes through 1,3-dipolar cycloaddition of sydnones with arynes has been described. The origins of the unconventional regioselectivity were systematically investigated using density functional theory calculations, unveiling the key features that control this reactivity and leading to the discovery of a derivative with reversible CPL sign inversion properties.
Article
Chemistry, Multidisciplinary
Daniel Wassy, Mathias Hermann, Jan S. Wossner, Lucas Frederic, Gregory Pieters, Birgit Esser
Summary: This study presents a strategy for the synthesis of enantiopure nanohoops with high fluorescence quantum yields and circularly polarized luminescence properties through chiral derivatization. Due to their strained structures, the DBP[n]CPPs do not racemize at room temperature, as supported by high calculated isomerization barriers. X-ray crystallographic investigations and DFT calculations provide insights into the build-up of strain energy during the synthetic transformations.
Article
Chemistry, Multidisciplinary
Kais Dhbaibi, Laura Abella, Sylvia Meunier-Della-Gatta, Thierry Roisnel, Nicolas Vanthuyne, Bassem Jamoussi, Gregory Pieters, Benoit Racine, Etienne Quesnel, Jochen Autschbach, Jeanne Crassous, Ludovic Favereau
Summary: The study reports the synthesis and chiroptical properties of a new family of pi-helical push-pull systems based on carbo[6]helicene, showing that the magnitude and relative orientation of the electric and magnetic dipole transition moments can efficiently tune the molecular chiroptical properties for enhanced CPL intensity. By optimizing the orientation of the electric and magnetic dipoles in the excited state, intense helicene-mediated exciton coupling was achieved, leading to strong CPL. The fabrication of top-emission CP-OLEDs through vapor deposition resulted in promising g(El) values, contributing to further molecular design guidelines and providing insights into innovative CP-OLED architectures.
Article
Chemistry, Multidisciplinary
Noel Pairault, Adrien Bessaguet, Romain Barat, Lucas Frederic, Gregory Pieters, Jeanne Crassous, Isabelle Opalinski, Sebastien Papot
Summary: This study presents the first diastereoselective synthesis of mechanically planar chiral [1]rotaxanes using the active template Cu-mediated alkyne-azide cycloaddition reaction. This synthetic method allows for the preparation of a variety of mechanically planar chiral [1]rotaxanes, paving the way for the study of their properties and potential applications.
Review
Chemistry, Multidisciplinary
Dan He, Yawen Li, Fuwen Zhao, Yuze Lin
Summary: High trap density in organic solar cells leads to localized charge carriers and reduced carrier lifetime, limiting device efficiency. This feature article summarizes the recent advances of trap suppression by material design and device engineering.
CHEMICAL COMMUNICATIONS
(2024)
Review
Chemistry, Multidisciplinary
Olivier Monfort, Arshitha Madhusudhan, Martin Motola
Summary: This article presents the advantages of coupling photocatalysis and Fenton-based processes for environmental remediation and discusses their synergy. It critically examines the simultaneous triggering of these two processes and provides insights into research approaches. The study aims to enhance understanding of this complex process and highlight the potential integration of new catalysts in current wastewater treatment technology.
CHEMICAL COMMUNICATIONS
(2024)
Article
Chemistry, Multidisciplinary
Manideepa Dhar, Chittaranjan Mishra, Avijit Das, Uttam Manna
Summary: An approach of 'polymerization of monomers in its aggregated form' has been introduced to tailor the water wettability of fibrous and porous substrates, achieving hydrophobicity to superhydrophobicity transition, as well as patterned wettability. This facile chemical method provides a durable coating with adjustable and patterned wettability for various potential applications.
CHEMICAL COMMUNICATIONS
(2024)
Article
Chemistry, Multidisciplinary
Saswat Ranjan Bhoi, Chhanda Debnath, Shikha Gandhi
Summary: In this article, a novel catalytic reaction using Pd(0) and Bronsted acid is reported for the synthesis of biologically important imidazolidinone-fused N-heterocycles through redox-neutral intramolecular N-allylation of indoles and pyrroles with alkynes. This atom-economical method is applicable to a wide range of substrates and eliminates the need for leaving groups or oxidizing agents commonly used in traditional allylation reactions.
CHEMICAL COMMUNICATIONS
(2024)
Article
Chemistry, Multidisciplinary
Longkun Chen, Mingshuai Zhang, Meichen Liu, Zhuoyuan Liu, Yuetong Qiu, Zhilai Zhang, Fuchao Yu, Jiuzhong Huang
Summary: In this study, an efficient Rh(III)-catalyzed selective mono- and dual-C-H bond functionalization/cyclization with iodonium ylide as the sole coupling partner was demonstrated. Fused benzodiazepine skeletons were obtained in excellent yields, providing an improved approach to dual C-H unsymmetrical functionalization.
CHEMICAL COMMUNICATIONS
(2024)
Article
Chemistry, Multidisciplinary
Alice Kennett, Sven Epple, Gabriella van der Valk, Irene Georgiou, Evelyne Gout, Romain R. Vives, Angela J. Russell
Summary: This study presents the design and synthesis of sulfated disaccharide inhibitors based on IdoA(2S)-GlcNS(6S), which showed potent inhibition of Sulf-2. The results suggest that IdoA(2S)-GlcNS(6S) is the shortest fragment size required for effective inhibition of Sulfs, and a trisulfated disaccharide is identified as the minimal fragment size of heparan sulfate for effective endosulfatase inhibition.
CHEMICAL COMMUNICATIONS
(2024)
Article
Chemistry, Multidisciplinary
Mauro Garbini, Andrea Brunetti, Riccardo Pedrazzani, Magda Monari, Massimo Marcaccio, Giulio Bertuzzi, Marco Bandini
Summary: The self-adaptability of galvanostatic electrolysis was found to be helpful in a multistage chemo- and diastereoselective electrochemically promoted cyclodimerization of chalcones. Through a series of reductive events, densely functionalized cyclopentanes with five contiguous stereocenters were obtained (25 examples, yields up to 95%, dr values up to >20:1). Further experimental and electrochemical investigations indicated the crucial role of dynamic kinetic resolution of the aldol intermediate in the reaction mechanism.
CHEMICAL COMMUNICATIONS
(2024)
Article
Chemistry, Multidisciplinary
Dhananjay S. Nipate, Neha Meena, Prakash N. Swami, Krishnan Rangan, Anil Kumar
Summary: In this study, the synthesis of functionalized benzo[a]phenazines and indazolo[2,3-a]quinolines was achieved through Rh(III)-catalyzed oxidative annulation of 2-arylquinoxalines and 2-aryl-2H-indazoles with allyl alcohols. The method showed a wide substrate scope, excellent functional group tolerance, good to high yields of annulated products, and the capability for scaled-up synthesis. A tentative mechanism of the annulation reaction was proposed based on a preliminary mechanistic investigation.
CHEMICAL COMMUNICATIONS
(2024)
Article
Chemistry, Multidisciplinary
Ruonan Zhang, Abudukadi Tudi, Xia Yang, Xuping Wang, Zhihua Yang, Shujuan Han, Shilie Pan
Summary: A new lead tellurium borate material with a unique fundamental building block [B4O10] was synthesized and found to exhibit high birefringence. The structure-property relationship was discussed using first-principles calculations.
CHEMICAL COMMUNICATIONS
(2024)
Article
Chemistry, Multidisciplinary
Amresh Kumar Singh, Baishali Thakurta, Anupam Giri, Monalisa Pal
Summary: This study introduces three key concepts for the quick synthesis of large-scale high-quality 2D materials films and their utilization in device fabrication.
CHEMICAL COMMUNICATIONS
(2024)
Article
Chemistry, Multidisciplinary
Reina Hagiwara, Shun Nishimura, Kosuke Okeyoshi
Summary: A copolymer-conjugated nanocatalytic system has been developed to improve electron transfer and enhance photoinduced H2 generation.
CHEMICAL COMMUNICATIONS
(2024)
