Bilirubin: The yellow hormone?

Bilirubin as a signaling molecule

(2020) Libor Vítek   MEDICINAL RESEARCH REVIEWS

Bilirubin, Intestinal Integrity, the Microbiome, and Inflammation

(2020) Libor Vítek et al.   NEW ENGLAND JOURNAL OF MEDICINE

Serum Bilirubin in the Czech Population　― Relationship to the Risk of Myocardial Infarction in Males ―

(2020) Lenka Eremiasova et al.   CIRCULATION JOURNAL

Identification of a bilirubin receptor that may mediate a component of cholestatic itch

(2019) James Meixiong et al.   eLife

The liver as an endocrine organ - linking NAFLD and insulin resistance

(2019) Matthew J Watt et al.   ENDOCRINE REVIEWS

Bilirubin as a predictor of diseases of civilization. Is it time to establish decision limits for serum bilirubin concentrations?

(2019) Libor Vítek   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Biliverdin reductase and bilirubin in hepatic disease

(2018) Lauren Weaver et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Mild hyperbilirubinaemia as an endogenous mitigator of overweight and obesity: Implications for improved metabolic health

(2018) Nazlisadat Seyed Khoei et al.   ATHEROSCLEROSIS

Diagnostic criteria and contributors to Gilbert’s syndrome

(2018) Karl-Heinz Wagner et al.   CRITICAL REVIEWS IN CLINICAL LABORATORY SCIENCES

Induction of mild hyperbilirubinemia: Hype or real therapeutic opportunity?

(2018) Libor Vitek et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

The role of bile acids in metabolic regulation

(2016) Libor Vítek et al.   JOURNAL OF ENDOCRINOLOGY

A Novel Perspective on the Biology of Bilirubin in Health and Disease

(2016) Silvia Gazzin et al.   TRENDS IN MOLECULAR MEDICINE

Bilirubin Binding to PPARα Inhibits Lipid Accumulation

(2016) David E. Stec et al.   PLoS One

Looking to the horizon: the role of bilirubin in the development and prevention of age-related chronic diseases

(2015) Karl-Heinz Wagner et al.   CLINICAL SCIENCE

The past 10 years—new hormones, new functions, new endocrine organs

(2015) Roger Bouillon et al.   Nature Reviews Endocrinology

Bilirubin Increases Insulin Sensitivity by Regulating Cholesterol Metabolism, Adipokines and PPARγ Levels

(2015) Jinfeng Liu et al.   Scientific Reports

Lineage-Specific Changes in Biomarkers in Great Apes and Humans

(2015) Claudius Ronke et al.   PLoS One

The heart as an endocrine organ

(2014) Tsuneo Ogawa et al.   Endocrine Connections

Where genotype is not predictive of phenotype: towards an understanding of the molecular basis of reduced penetrance in human inherited disease

(2013) David N. Cooper et al.   HUMAN GENETICS

The molecular basis for the immunomodulatory activities of unconjugated bilirubin

(2013) Sushrut Jangi et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Evidence for regulation of UDP-glucuronosyltransferase (UGT) 1A1 protein expression and activity via DNA methylation in healthy human livers

(2013) Umit Yasar et al.   JOURNAL OF PHARMACY AND PHARMACOLOGY

PharmGKB summary

(2013) Julia M. Barbarino et al.   Pharmacogenetics and Genomics

The Role of Bilirubin in Diabetes, Metabolic Syndrome, and Cardiovascular Diseases

(2012) Libor Vítek   Frontiers in Pharmacology

Reference Intervals for Common Laboratory Tests in Melanesian Children

(2011) Laurens Manning et al.   AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE

Gilbert syndrome redefined: A complex genetic haplotype influences the regulation of glucuronidation

(2011) Ursula Ehmer et al.   HEPATOLOGY

Serum Bilirubin and Genes Controlling Bilirubin Concentrations as Biomarkers for Cardiovascular Disease

(2010) J.-P. Lin et al.   CLINICAL CHEMISTRY

Gilbert-Meulengracht’s syndrome and pharmacogenetics: is jaundice just the tip of the iceberg?

(2009) Christian P. Strassburg   DRUG METABOLISM REVIEWS