Evidence for regulation of UDP-glucuronosyltransferase (UGT) 1A1 protein expression and activity via DNA methylation in healthy human livers

Cancer epigenetics reaches mainstream oncology

(2011) Manuel Rodríguez-Paredes et al.   NATURE MEDICINE

Quantitative distribution of mRNAs encoding the 19 human UDP-glucuronosyltransferase enzymes in 26 adult and 3 fetal tissues

(2011) Michael H. Court et al.   XENOBIOTICA

Regulation of UGT1A1 and HNF1 transcription factor gene expression by DNA methylation in colon cancer cells

(2010) Anne-Sophie Belanger et al.   BMC MOLECULAR BIOLOGY

Correlation between Bilirubin Glucuronidation and Estradiol-3-Gluronidation in the Presence of Model UDP-Glucuronosyltransferase 1A1 Substrates/Inhibitors

(2010) J. Zhou et al.   DRUG METABOLISM AND DISPOSITION

Variation, patterns, and temporal stability of DNA methylation: considerations for epigenetic epidemiology

(2010) Rudolf P. Talens et al.   FASEB JOURNAL

Interindividual variability in hepatic drug glucuronidation: studies into the role of age, sex, enzyme inducers, and genetic polymorphism using the human liver bank as a model system

(2009) Michael H. Court   DRUG METABOLISM REVIEWS

Can UGT1A1 genotyping reduce morbidity and mortality in patients with metastatic colorectal cancer treated with irinotecan? An evidence-based review

(2009) Glenn E Palomaki et al.   GENETICS IN MEDICINE

Interindividual Variability in Pharmacokinetics of Generic Nucleoside Reverse Transcriptase Inhibitors in TB/HIV-Coinfected Ghanaian Patients:UGT2B7*1c Is Associated With Faster Zidovudine Clearance and Glucuronidation

(2009) Awewura Kwara et al.   JOURNAL OF CLINICAL PHARMACOLOGY

A simple algorithm for quantifying DNA methylation levels on multiple independent CpG sites in bisulfite genomic sequencing electropherograms

(2008) T. I. Leakey et al.   NUCLEIC ACIDS RESEARCH