Superporous agarose scaffolds for encapsulation of adult human islets and human stem‐cell‐derived β cells for intravascular bioartificial pancreas applications

Targeting the cytoskeleton to direct pancreatic differentiation of human pluripotent stem cells

(2020) Nathaniel J. Hogrebe et al.   NATURE BIOTECHNOLOGY

Acquisition of Dynamic Function in Human Stem Cell-Derived β Cells

(2019) Leonardo Velazco-Cruz et al.   Stem Cell Reports

Recapitulating endocrine cell clustering in culture promotes maturation of human stem-cell-derived β cells

(2019) Gopika G. Nair et al.   NATURE CELL BIOLOGY

Paving the way for successful islet encapsulation

(2019) Nikos Dimitrioglou et al.   DRUG DISCOVERY TODAY

Stem Cell-Derived Pancreatic Progenitor Cells Have Now Been Transplanted into Patients: Report from IPITA 2018

(2018) Lara C. Pullen   AMERICAN JOURNAL OF TRANSPLANTATION

Generation of pancreatic β cells for treatment of diabetes: advances and challenges

(2018) Hussain Md. Shahjalal et al.   Stem Cell Research & Therapy

An intravascular bioartificial pancreas device (iBAP) with silicon nanopore membranes (SNM) for islet encapsulation under convective mass transport

(2017) Shang Song et al.   LAB ON A CHIP

Progress and challenges in macroencapsulation approaches for type 1 diabetes (T1D) treatment: Cells, biomaterials, and devices

(2016) Shang Song et al.   BIOTECHNOLOGY AND BIOENGINEERING

National Institutes of Health–Sponsored Clinical Islet Transplantation Consortium Phase 3 Trial: Manufacture of a Complex Cellular Product at Eight Processing Facilities

(2016) Camillo Ricordi et al.   DIABETES

Phase 3 Trial of Transplantation of Human Islets in Type 1 Diabetes Complicated by Severe Hypoglycemia

(2016) Bernhard J. Hering et al.   DIABETES CARE

Long-term glycemic control using polymer-encapsulated human stem cell–derived beta cells in immune-competent mice

(2016) Arturo J Vegas et al.   NATURE MEDICINE

Advances in islet encapsulation technologies

(2016) Tejal Desai et al.   NATURE REVIEWS DRUG DISCOVERY

An Abbreviated Protocol for In Vitro Generation of Functional Human Embryonic Stem Cell-Derived Beta-Like Cells

(2016) Mohammad Massumi et al.   PLoS One

Dynamics and Regulation of Insulin Secretion in Pancreatic Islets from Normal Young Children

(2016) Jean-Claude Henquin et al.   PLoS One

Silicon nanopore membrane (SNM) for islet encapsulation and immunoisolation under convective transport

(2016) Shang Song et al.   Scientific Reports

Controlled induction of human pancreatic progenitors produces functional beta-like cells in vitro

(2015) H. A. Russ et al.   EMBO JOURNAL

Oxygen supply to encapsulated therapeutic cells

(2014) Clark K. Colton   ADVANCED DRUG DELIVERY REVIEWS

Generation of Functional Human Pancreatic β Cells In Vitro

(2014) Felicia W. Pagliuca et al.   CELL

Reversal of diabetes with insulin-producing cells derived in vitro from human pluripotent stem cells

(2014) Alireza Rezania et al.   NATURE BIOTECHNOLOGY

Differentiated human stem cells resemble fetal, not adult, β cells

(2014) Sinisa Hrvatin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Physiological Pattern of Oxygenation Using Perfluorocarbon-Based Culture Devices Maximizes Pancreatic Islet Viability and Enhances β-Cell Function

(2013) Chris A. Fraker et al.   CELL TRANSPLANTATION

Fiji: an open-source platform for biological-image analysis

(2012) Johannes Schindelin et al.   NATURE METHODS

Improvement of islet function in a bioartificial pancreas by enhanced oxygen supply and growth hormone releasing hormone agonist

(2012) B. Ludwig et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Perfluorodecalin-enriched fibrin matrix for human islet culture

(2011) Elisa Maillard et al.   BIOMATERIALS

INS GFP/w human embryonic stem cells facilitate isolation of in vitro derived insulin-producing cells

(2011) S. J. Micallef et al.   DIABETOLOGIA

Islet-enriched gene expression and glucose-induced insulin secretion in human and mouse islets

(2011) C. Dai et al.   DIABETOLOGIA

Advancing islet transplantation: from engraftment to the immune response

(2011) R. F. Gibly et al.   DIABETOLOGIA

Islets Transplanted in Immunoisolation Devices: A Review of the Progress and the Challenges that Remain

(2011) Esther S. O'Sullivan et al.   ENDOCRINE REVIEWS

Large human islets secrete less insulin per islet equivalent than smaller islets in vitro

(2011) Yasutaka Fujita et al.   Islets

Bioartificial pancreas☆Microencapsulation and conformal coating of islet of Langerhans

(2010) Yuji Teramura et al.   ADVANCED DRUG DELIVERY REVIEWS

Highly efficient differentiation of human ES cells and iPS cells into mature pancreatic insulin-producing cells

(2009) Donghui Zhang et al.   CELL RESEARCH

Pancreas transplantation

(2009) Steve A White et al.   LANCET