Network Pharmacology Study on Morus alba L. Leaves: Pivotal Functions of Bioactives on RAS Signaling Pathway and Its Associated Target Proteins against Gout

Screening of natural compounds from Cyperus rotundus Linn against SARS-CoV-2 main protease (Mpro): An integrated computational approach

(2021) S. Birendra Kumar et al.   COMPUTERS IN BIOLOGY AND MEDICINE

Central and peripheral pain intervention by Ophiorrhiza rugosa leaves: Potential underlying mechanisms and insight into the role of pain modulators

(2021) Md. Nazim Uddin Chy et al.   JOURNAL OF ETHNOPHARMACOLOGY

Network Pharmacology Study to Interpret Signaling Pathways of Ilex cornuta Leaves against Obesity

(2021) Ki-Kwang Oh et al.   Processes

Uncovering Mechanisms of Zanthoxylum piperitum Fruits for the Alleviation of Rheumatoid Arthritis Based on Network Pharmacology

(2021) Kikwang Oh et al.   Biology-Basel

Chinese herbal medicine for gout: a review of the clinical evidence and pharmacological mechanisms

(2020) Xiansu Chi et al.   Chinese Medicine

Virtual screening web servers: designing chemical probes and drug candidates in the cyberspace

(2020) Natesh Singh et al.   BRIEFINGS IN BIOINFORMATICS

P2Y14 receptor has a critical role in acute gouty arthritis by regulating pyroptosis of macrophages

(2020) Hanwen Li et al.   Cell Death & Disease

Proteomic analysis of human synovial fluid reveals potential diagnostic biomarkers for ankylosing spondylitis

(2020) Ji-Hyun Lee et al.   Clinical Proteomics

Kenaf (Hibiscus cannabinus L.) Leaves and Seed as a Potential Source of the Bioactive Compounds: Effects of Various Extraction Solvents on Biological Properties

(2020) Md. Adnan et al.   Life-Basel

Active ingredients and mechanisms of Phellinus linteus (grown on Rosa multiflora) for alleviation of Type 2 diabetes mellitus through network pharmacology

(2020) Ki Kwang Oh et al.   GENE

Network Pharmacology Databases for Traditional Chinese Medicine: Review and Assessment

(2019) Runzhi Zhang et al.   Frontiers in Pharmacology

New lupeol esters as active substances in the treatment of skin damage

(2019) Magdalena Malinowska et al.   PLoS One

Phagocytosis of monosodium urate crystals by human synoviocytes induces inflammation

(2019) Yessica Zamudio-Cuevas et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

AMPK alleviates high uric acid-induced Na+-K+-ATPase signaling impairment and cell injury in renal tubules

(2019) Jing Xiao et al.   EXPERIMENTAL AND MOLECULAR MEDICINE

Evaluation of anti-nociceptive and anti-inflammatory activities of the methanol extract of Holigarna caustica (Dennst.) Oken leaves

(2019) Md. Adnan et al.   JOURNAL OF ETHNOPHARMACOLOGY

SwissTargetPrediction: updated data and new features for efficient prediction of protein targets of small molecules

(2019) Antoine Daina et al.   NUCLEIC ACIDS RESEARCH

IgE-mediated mast cell activation promotes inflammation and cartilage destruction in osteoarthritis

(2019) Qian Wang et al.   eLife

Systems biology and network pharmacology of frailty reveal novel epigenetic targets and mechanisms

(2019) J. C. Gomez-Verjan et al.   Scientific Reports

Gout

(2019) Nicola Dalbeth et al.   Nature Reviews Disease Primers

Vascular endothelial growth factor expression and their action in the synovial membranes of patients with painful knee osteoarthritis

(2018) Shotaro Takano et al.   BMC MUSCULOSKELETAL DISORDERS

In vitro bioaccessibility and physicochemical properties of phytosterol linoleic ester synthesized from soybean sterol and linoleic acid

(2018) Fuming Yang et al.   LWT-FOOD SCIENCE AND TECHNOLOGY

Anti-inflammatory effects of mulberry (Morus alba L.) root bark and its active compounds

(2018) Yong-Xiang Wu et al.   NATURAL PRODUCT RESEARCH

STRING v11: protein–protein association networks with increased coverage, supporting functional discovery in genome-wide experimental datasets

(2018) Damian Szklarczyk et al.   NUCLEIC ACIDS RESEARCH

Painful Understanding of VEGF

(2018) María Llorián-Salvador et al.   Frontiers in Pharmacology

Genome-wide association scan of neuropathic pain symptoms post total joint replacement highlights a variant in the protein-kinase C gene

(2017) Sophie C Warner et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

Cell-type-specific gene expression patterns in the knee cartilage in an osteoarthritis rat model

(2017) Michal Korostynski et al.   FUNCTIONAL & INTEGRATIVE GENOMICS

How Big Is Too Big for Cell Permeability?

(2017) Pär Matsson et al.   JOURNAL OF MEDICINAL CHEMISTRY

Synovial membrane receptors as therapeutic targets: A review of receptor localization, structure, and function

(2017) Stephanie A. Kleine et al.   JOURNAL OF ORTHOPAEDIC RESEARCH

Uric acid priming in human monocytes is driven by the AKT–PRAS40 autophagy pathway

(2017) Tania O. Crişan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Uric Acid Induces Endothelial Dysfunction by Activating the HMGB1/RAGE Signaling Pathway

(2017) Wei Cai et al.   Biomed Research International

Characteristics of antibacterial molecular activities in poplar wood extractives

(2017) Wanxi Peng et al.   SAUDI JOURNAL OF BIOLOGICAL SCIENCES

Network Pharmacology Studies on the Bioactive Compounds and Action Mechanisms of Natural Products for the Treatment of Diabetes Mellitus: A Review

(2017) Weiwei Li et al.   Frontiers in Pharmacology

CD14+ Cells with the Phenotype of Infiltrated Monocytes Consist of Distinct Populations Characterized by Anti-inflammatory as well as Pro-inflammatory Activity in Gouty Arthritis

(2017) Ji Hye Jeong et al.   Frontiers in Immunology

Invariant Natural Killer T Cells Ameliorate Monosodium Urate Crystal-Induced Gouty Inflammation in Mice

(2017) Jie Wang et al.   Frontiers in Immunology

Gout: An old disease in new perspective – A review

(2017) Gaafar Ragab et al.   Journal of Advanced Research

Cudraflavone C Induces Tumor-Specific Apoptosis in Colorectal Cancer Cells through Inhibition of the Phosphoinositide 3-Kinase (PI3K)-AKT Pathway

(2017) Hsien-Chuen Soo et al.   PLoS One

SwissADME: a free web tool to evaluate pharmacokinetics, drug-likeness and medicinal chemistry friendliness of small molecules

(2017) Antoine Daina et al.   Scientific Reports

Management of Acute and Recurrent Gout: A Clinical Practice Guideline From the American College of Physicians

(2016) Amir Qaseem et al.   ANNALS OF INTERNAL MEDICINE

Protective Effect of Morus alba Leaf Extract on N-Nitrosodiethylamine-induced Hepatocarcinogenesis in Rats

(2016) MAŁGORZATA KUJAWSKA et al.   IN VIVO

Bioactive Dihydro-β-agarofuran Sesquiterpenoids from the Australian Rainforest Plant Maytenus bilocularis

(2016) Mario Wibowo et al.   JOURNAL OF NATURAL PRODUCTS

The association of vitamin C, alcohol, coffee, tea, milk and yogurt with uric acid and gout

(2015) Patapong Towiwat et al.   International Journal of Rheumatic Diseases

Wnt signaling in cartilage development and diseases: lessons from animal studies

(2015) Yu Usami et al.   LABORATORY INVESTIGATION

Colchicine—Update on mechanisms of action and therapeutic uses

(2015) Ying Ying Leung et al.   SEMINARS IN ARTHRITIS AND RHEUMATISM

Nocturnal Risk of Gout Attacks

(2015) Hyon K. Choi et al.   Arthritis & Rheumatology

Anti-inflammatory and anti-cancer activity of mulberry (Morus alba L.) root bark

(2014) Hyun Ji Eo et al.   BMC Complementary and Alternative Medicine

Natural forms of vitamin E: metabolism, antioxidant, and anti-inflammatory activities and their role in disease prevention and therapy

(2014) Qing Jiang   FREE RADICAL BIOLOGY AND MEDICINE

Increased Antioxidant Efficacy of Tocopherols by Surfactant Solubilization in Oil-in-Water Emulsions

(2014) S. Sezer Kiralan et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Sphingolipids in Human Synovial Fluid - A Lipidomic Study

(2014) Marta Krystyna Kosinska et al.   PLoS One

Antibacterial Activity and Kinetics of Litsea cubeba Oil on Escherichia coli

(2014) Wen-Ru Li et al.   PLoS One

Network Pharmacology: A New Approach for Chinese Herbal Medicine Research

(2013) Gui-biao Zhang et al.   Evidence-based Complementary and Alternative Medicine

Identification of 2,3-dihydro-3,5-dihydroxy-6-methyl-4H-pyran-4-one as a strong antioxidant in glucose–histidine Maillard reaction products

(2013) Xiangying Yu et al.   FOOD RESEARCH INTERNATIONAL

Promoter RNA links transcriptional regulation of inflammatory pathway genes

(2013) Masayuki Matsui et al.   NUCLEIC ACIDS RESEARCH

Vitamin E in aging, dementia, and Alzheimer's disease

(2012) Yash B. Joshi et al.   BIOFACTORS

Thyroid Hormones as Modulators of Immune Activities at the Cellular Level

(2011) Paolo De Vito et al.   THYROID

Mechanisms of inflammation in gout

(2010) Nathalie Busso et al.   ARTHRITIS RESEARCH & THERAPY

Fat and Fatty Acid Terminology, Methods of Analysis and Fat Digestion and Metabolism: A Background Review Paper

(2009) W.M. Nimal Ratnayake et al.   ANNALS OF NUTRITION AND METABOLISM

Akt1 is critical for acute inflammation and histamine-mediated vascular leakage

(2009) A. Di Lorenzo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA