AMPK alleviates high uric acid-induced Na+-K+-ATPase signaling impairment and cell injury in renal tubules

Uric Acid and the Risks of Kidney Failure and Death in Individuals With CKD

(2018) Anand Srivastava et al.   AMERICAN JOURNAL OF KIDNEY DISEASES

FOXO Signaling Pathways as Therapeutic Targets in Cancer

(2017) Mohd Farhan et al.   International Journal of Biological Sciences

Metformin ameliorates high uric acid-induced insulin resistance in skeletal muscle cells

(2017) Huier Yuan et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Fructose-1,6-bisphosphate and aldolase mediate glucose sensing by AMPK

(2017) Chen-Song Zhang et al.   NATURE

AMPK: guardian of metabolism and mitochondrial homeostasis

(2017) Sébastien Herzig et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Uric acid predicts adverse outcomes in chronic kidney disease: a novel insight from trajectory analyses

(2017) Ching-Wei Tsai et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Metformin Activates AMPK through the Lysosomal Pathway

(2016) Chen-Song Zhang et al.   Cell Metabolism

High Uric Acid Activates the ROS-AMPK Pathway, Impairs CD68 Expression and Inhibits OxLDL-Induced Foam-Cell Formation in a Human Monocytic Cell Line, THP-1

(2016) Chaohuan Luo et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Regulation of AMP-activated protein kinase by natural and synthetic activators

(2016) David Grahame Hardie   Acta Pharmaceutica Sinica B

Soluble uric acid increases NALP3 inflammasome and interleukin-1β expression in human primary renal proximal tubule epithelial cells through the Toll-like receptor 4-mediated pathway

(2015) JING XIAO et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

Soluble monosodium urate, but not its crystal, induces toll like receptor 4-dependent immune activation in renal mesangial cells

(2015) Jing Xiao et al.   MOLECULAR IMMUNOLOGY

AMP-activated protein kinase suppresses urate crystal-induced inflammation and transduces colchicine effects in macrophages

(2014) Yun Wang et al.   ANNALS OF THE RHEUMATIC DISEASES

Fatty acids are novel nutrient factors to regulate mTORC1 lysosomal localization and apoptosis in podocytes

(2014) Mako Yasuda et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

The Lysosomal v-ATPase-Ragulator Complex Is a Common Activator for AMPK and mTORC1, Acting as a Switch between Catabolism and Anabolism

(2014) Chen-Song Zhang et al.   Cell Metabolism

Requirement for lysosomal localization of mTOR for its activation differs between leucine and other amino acids

(2014) Julien Averous et al.   CELLULAR SIGNALLING

Regulation of ion channels and transporters by AMP-activated kinase (AMPK)

(2013) Florian Lang et al.   Channels

Ouabain-induced Internalization and Lysosomal Degradation of the Na+/K+-ATPase

(2013) Marina Cherniavsky-Lev et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Uric acid induces oxidative stress and growth inhibition by activating adenosine monophosphate-activated protein kinase and extracellular signal-regulated kinase signal pathways in pancreatic β cells

(2013) Yongneng Zhang et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Activation of AMP-activated Protein Kinase Stimulates Na+,K+-ATPase Activity in Skeletal Muscle Cells

(2012) Boubacar Benziane et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Uric Acid Induces Renal Inflammation via Activating Tubular NF-κB Signaling Pathway

(2012) Yang Zhou et al.   PLoS One

Regulation of Uric Acid Excretion by the Kidney

(2012) Michael S. Lipkowitz   Current Rheumatology Reports

Hypoxia Leads to Na,K-ATPase Downregulation via Ca2+ Release-Activated Ca2+ Channels and AMPK Activation

(2011) G. A. Gusarova et al.   MOLECULAR AND CELLULAR BIOLOGY

AS160 Associates with the Na+,K+-ATPase and Mediates the Adenosine Monophosphate-stimulated Protein Kinase-dependent Regulation of Sodium Pump Surface Expression

(2010) Daiane S. Alves et al.   MOLECULAR BIOLOGY OF THE CELL

 1-AMP-Activated Protein Kinase Regulates Hypoxia-Induced Na,K-ATPase Endocytosis via Direct Phosphorylation of Protein Kinase C 

(2009) G. A. Gusarova et al.   MOLECULAR AND CELLULAR BIOLOGY

Nutrient-dependent mTORC1 Association with the ULK1–Atg13–FIP200 Complex Required for Autophagy

(2009) Nao Hosokawa et al.   MOLECULAR BIOLOGY OF THE CELL

Sirt1 protects against oxidative stress-induced renal tubular cell apoptosis by the bidirectional regulation of catalase expression

(2008) Kazuhiro Hasegawa et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

AMPK Phosphorylation of Raptor Mediates a Metabolic Checkpoint

(2008) Dana M. Gwinn et al.   MOLECULAR CELL

Pharmacological activators of AMP-activated protein kinase have different effects on Na+ transport processes across human lung epithelial cells

(2007) A M Woollhead et al.   BRITISH JOURNAL OF PHARMACOLOGY