Promoter RNA links transcriptional regulation of inflammatory pathway genes

Long Non-Coding RNA Targeting and Transcriptional De-Repression

(2015) Marc S. Weinberg et al.   Nucleic Acid Therapeutics

Digital Quantitation of Potential Therapeutic Target RNAs

(2015) David W. Dodd et al.   Nucleic Acid Therapeutics

ZFN, TALEN, and CRISPR/Cas-based methods for genome engineering

(2013) Thomas Gaj et al.   TRENDS IN BIOTECHNOLOGY

Host Genotype-Specific Therapies Can Optimize the Inflammatory Response to Mycobacterial Infections

(2012) David M. Tobin et al.   CELL

Extensive Promoter-Centered Chromatin Interactions Provide a Topological Basis for Transcription Regulation

(2012) Guoliang Li et al.   CELL

The long-range interaction landscape of gene promoters

(2012) Amartya Sanyal et al.   NATURE

Modular regulatory principles of large non-coding RNAs

(2012) Mitchell Guttman et al.   NATURE

Inhibition of natural antisense transcripts in vivo results in gene-specific transcriptional upregulation

(2012) Farzaneh Modarresi et al.   NATURE BIOTECHNOLOGY

The plasticity of WDR5 peptide-binding cleft enables the binding of the SET1 family of histone methyltransferases

(2012) Pamela Zhang et al.   NUCLEIC ACIDS RESEARCH

Manipulation of PK-M mutually exclusive alternative splicing by antisense oligonucleotides

(2012) Z. Wang et al.   Open Biology

Taking RISCs with Ago hookers

(2011) Jacinthe Azevedo et al.   CURRENT OPINION IN PLANT BIOLOGY

Silencing disease genes in the laboratory and the clinic

(2011) Jonathan K Watts et al.   JOURNAL OF PATHOLOGY

A long noncoding RNA maintains active chromatin to coordinate homeotic gene expression

(2011) Kevin C. Wang et al.   NATURE

Expanding the action of duplex RNAs into the nucleus: redirecting alternative splicing

(2011) Jing Liu et al.   NUCLEIC ACIDS RESEARCH

The Reality of Pervasive Transcription

(2011) Michael B. Clark et al.   PLOS BIOLOGY

Anti-inflammatory Agents: Present and Future

(2010) Charles A. Dinarello   CELL

Selective Transcription in Response to an Inflammatory Stimulus

(2010) Stephen T. Smale   CELL

Activation of LDL Receptor Expression by Small RNAs Complementary to a Noncoding Transcript that Overlaps the LDLR Promoter

(2010) Masayuki Matsui et al.   CHEMISTRY & BIOLOGY

Transcriptional regulation by small RNAs at sequences downstream from 3′ gene termini

(2010) Xuan Yue et al.   Nature Chemical Biology

Involvement of argonaute proteins in gene silencing and activation by RNAs complementary to a non-coding transcript at the progesterone receptor promoter

(2010) Yongjun Chu et al.   NUCLEIC ACIDS RESEARCH

Effect of chemical modifications on modulation of gene expression by duplex antigene RNAs that are complementary to non-coding transcripts at gene promoters

(2010) Jonathan K. Watts et al.   NUCLEIC ACIDS RESEARCH

Cyclooxygenase-2 Controls Energy Homeostasis in Mice by de Novo Recruitment of Brown Adipocytes

(2010) A. Vegiopoulos et al.   SCIENCE

Long Noncoding RNA as Modular Scaffold of Histone Modification Complexes

(2010) M.-C. Tsai et al.   SCIENCE

Transcriptional Scaffolds for Heterochromatin Assembly

(2009) Hugh P. Cam et al.   CELL

Genetic Interaction of PGE2 and Wnt Signaling Regulates Developmental Specification of Stem Cells and Regeneration

(2009) Wolfram Goessling et al.   CELL

siRNA and Innate Immunity

(2009) Marjorie Robbins et al.   OLIGONUCLEOTIDES

The GW182 protein family in animal cells: New insights into domains required for miRNA-mediated gene silencing

(2009) A. Eulalio et al.   RNA

The C-terminal half of human Ago2 binds to multiple GW-rich regions of GW182 and requires GW182 to mediate silencing

(2009) S. L. Lian et al.   RNA

Structure of an argonaute silencing complex with a seed-containing guide DNA and target RNA duplex

(2008) Yanli Wang et al.   NATURE

Antisense transcripts are targets for activating small RNAs

(2008) Jacob C Schwartz et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Intersection of the RNA Interference and X-Inactivation Pathways

(2008) Y. Ogawa et al.   SCIENCE

Bidirectional Transcription Directs Both Transcriptional Gene Activation and Suppression in Human Cells

(2008) Kevin V. Morris et al.   PLoS Genetics