Battling Chemoresistance in Cancer: Root Causes and Strategies to Uproot Them
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Title
Battling Chemoresistance in Cancer: Root Causes and Strategies to Uproot Them
Authors
Keywords
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Journal
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
Volume 22, Issue 17, Pages 9451
Publisher
MDPI AG
Online
2021-08-31
DOI
10.3390/ijms22179451
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Note: Only part of the references are listed.- Global cancer statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries
- (2021) Hyuna Sung et al. CA-A CANCER JOURNAL FOR CLINICIANS
- DNA Repair Pathways in Cancer Therapy and Resistance
- (2021) Lan-ya Li et al. Frontiers in Pharmacology
- Cancer drug resistance induced by EMT: novel therapeutic strategies
- (2021) Javier De Las Rivas et al. ARCHIVES OF TOXICOLOGY
- A New Oxaliplatin Resistance-Related Gene Signature With Strong Predicting Ability in Colon Cancer Identified by Comprehensive Profiling
- (2021) Qiu Lin et al. Frontiers in Oncology
- microRNA-499a promotes the progression and chemoresistance of cervical cancer cells by targeting SOX6
- (2020) Yibing Chen et al. APOPTOSIS
- Cisplatin resistance in gastric cancer cells is involved with GPR30‐mediated epithelial‐mesenchymal transition
- (2020) Xiaofeng Wang et al. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
- Oral administration of protein nanoparticles: An emerging route to disease treatment
- (2020) Samira Sadeghi et al. PHARMACOLOGICAL RESEARCH
- Functional and transcriptomic characterization of cisplatin-resistant AGS and MKN-28 gastric cancer cell lines
- (2020) Barbara Mora-Lagos et al. PLoS One
- Tumor microenvironment complexity and therapeutic implications at a glance
- (2020) Roghayyeh Baghban et al. Cell Communication and Signaling
- Mechanisms of Multidrug Resistance in Cancer Chemotherapy
- (2020) Karol Bukowski et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- The anti-tumor activity of pralatrexate (PDX) correlates with the expression of RFC and DHFR mRNA in preclinical models of multiple myeloma
- (2020) Cristina Kinahan et al. Oncotarget
- Fluctuating expression of miR-584 in primary and high-grade gastric cancer
- (2020) Laleh Ebrahimi Ghahnavieh et al. BMC CANCER
- Long non-coding RNA: A recently accentuated molecule in chemoresistance in cancer
- (2020) Yang Peng et al. CANCER AND METASTASIS REVIEWS
- Hippo/MST blocks breast cancer by downregulating WBP2 oncogene expression via miRNA processor Dicer
- (2020) Shen Kiat Lim et al. Cell Death & Disease
- LINC00641/miR-582-5p mediate oxaliplatin resistance by activating autophagy in gastric adenocarcinoma
- (2020) Yunfeng Hu et al. Scientific Reports
- GDF15 Repression Contributes to 5-Fluorouracil Resistance in Human Colon Cancer by Regulating Epithelial-Mesenchymal Transition and Apoptosis
- (2020) Bin Wang et al. Biomed Research International
- Counteracting Chemoresistance with Metformin in Breast Cancers: Targeting Cancer Stem Cells
- (2020) Samson Mathews Samuel et al. Cancers
- The role and mechanisms of action of microRNAs in cancer drug resistance
- (2019) Wengong Si et al. Clinical Epigenetics
- Sirtuin-mediated deacetylation of hnRNP A1 suppresses glycolysis and growth in hepatocellular carcinoma
- (2019) Hao Yang et al. ONCOGENE
- Increasing the dose intensity of chemotherapy by more frequent administration or sequential scheduling: a patient-level meta-analysis of 37 298 women with early breast cancer in 26 randomised trials
- (2019) Richard Gray et al. LANCET
- Combined inhibition of STAT3 and DNA repair in palbociclib-resistant ER-positive breast cancer
- (2019) Nicole M. Kettner et al. CLINICAL CANCER RESEARCH
- Cisplatin resistant lung cancer cells promoted M2 polarization of tumor-associated macrophages via the Src/CD155/MIF functional pathway
- (2019) Wen-Chien Huang et al. JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
- The roles of glucose metabolic reprogramming in chemo- and radio-resistance
- (2019) Jinguan Lin et al. JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
- Cancer-associated fibroblasts promote prostate cancer malignancy via metabolic rewiring and mitochondrial transfer
- (2019) Luigi Ippolito et al. ONCOGENE
- High expression of NFAT2 contributes to carboplatin resistance in lung cancer
- (2019) Xi Liu et al. EXPERIMENTAL AND MOLECULAR PATHOLOGY
- Epithelial-to-mesenchymal transition and drug resistance: transitioning away from death
- (2019) Kyung-A Song et al. Journal of Thoracic Disease
- Role of KEAP1/NFE2L2 mutations in the chemotherapeutic response of non-small cell lung cancer patients
- (2019) Youngtae Jeong et al. CLINICAL CANCER RESEARCH
- A view on drug resistance in cancer
- (2019) Neil Vasan et al. NATURE
- Circulating tumor DNA as an early cancer detection tool
- (2019) Andrea Campos-Carrillo et al. PHARMACOLOGY & THERAPEUTICS
- APC loss affects DNA damage repair causing doxorubicin resistance in breast cancer cells
- (2019) Casey D. Stefanski et al. NEOPLASIA
- Reversal of drug resistance by planetary ball milled (PBM) nanoparticle loaded with resveratrol and docetaxel in prostate cancer
- (2018) Santosh Kumar Singh et al. CANCER LETTERS
- Synergy between the KEAP1/NRF2 and PI3K Pathways Drives Non-Small-Cell Lung Cancer with an Altered Immune Microenvironment
- (2018) Sarah A. Best et al. Cell Metabolism
- Paracrine Wnt5a-β-Catenin Signaling Triggers a Metabolic Program that Drives Dendritic Cell Tolerization
- (2018) Fei Zhao et al. IMMUNITY
- Noncoding RNA:RNA Regulatory Networks in Cancer
- (2018) Jia Chan et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Effect of a Low-Intensity PSA-Based Screening Intervention on Prostate Cancer Mortality
- (2018) Richard M. Martin et al. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
- Rediscovery of NF-κB signaling in nasopharyngeal carcinoma: How genetic defects of NF-κB pathway interplay with EBV in driving oncogenesis?
- (2018) Mei Yi et al. JOURNAL OF CELLULAR PHYSIOLOGY
- Osimertinib in Untreated EGFR-Mutated Advanced Non–Small-Cell Lung Cancer
- (2018) Jean-Charles Soria et al. NEW ENGLAND JOURNAL OF MEDICINE
- Poldip2 is an oxygen-sensitive protein that controls PDH and αKGDH lipoylation and activation to support metabolic adaptation in hypoxia and cancer
- (2018) Felipe Paredes et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- NEAT1_2—SFPQ axis mediates cisplatin resistance in liver cancer cells in vitro
- (2018) Yi Ru et al. OncoTargets and Therapy
- Drug Resistance in Non-Small Cell Lung Cancer: A Potential for NOTCH Targeting?
- (2018) Venus Sosa Iglesias et al. Frontiers in Oncology
- Targeting Cancer Stem Cells to Overcome Chemoresistance
- (2018) Toni Nunes et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Maintenance Olaparib in Patients with Newly Diagnosed Advanced Ovarian Cancer
- (2018) Kathleen Moore et al. NEW ENGLAND JOURNAL OF MEDICINE
- Blood Transcript Profiling for the Detection of Neuroendocrine Tumors: Results of a Large Independent Validation Study
- (2018) Mark J. C. van Treijen et al. Frontiers in Endocrinology
- Sensitization of Drug Resistant Cancer Cells: A Matter of Combination Therapy
- (2018) Meghan Leary et al. Cancers
- The role of exosomes and miRNAs in drug-resistance of cancer cells
- (2017) Duc-Hiep Bach et al. INTERNATIONAL JOURNAL OF CANCER
- Implications of ABCG2 Expression on Irinotecan Treatment of Colorectal Cancer Patients: A Review
- (2017) Dorte Lisbet Nielsen et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- ABC Transporters in Cancer Stem Cells: Beyond Chemoresistance
- (2017) Romana-Rea Begicevic et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Acquired Resistance with Epigenetic Alterations Under Long-Term Antiangiogenic Therapy for Hepatocellular Carcinoma
- (2017) Yoshiteru Ohata et al. MOLECULAR CANCER THERAPEUTICS
- Strategies and challenges for the next generation of antibody–drug conjugates
- (2017) Alain Beck et al. NATURE REVIEWS DRUG DISCOVERY
- Alectinib versus Crizotinib in Untreated ALK-Positive Non–Small-Cell Lung Cancer
- (2017) Solange Peters et al. NEW ENGLAND JOURNAL OF MEDICINE
- Molecular alterations contributing to pancreatic cancer chemoresistance
- (2017) Azam Rajabpour et al. PANCREATOLOGY
- When less is more
- (2017) Jocelyn Kaiser SCIENCE
- A New View of Pathway-Driven Drug Resistance in Tumor Proliferation
- (2017) Ruth Nussinov et al. TRENDS IN PHARMACOLOGICAL SCIENCES
- LncRNA UCA1 in anti-cancer drug resistance
- (2017) Haohao Wang et al. Oncotarget
- The molecular mechanisms of chemoresistance in cancers
- (2017) Hua-Chuan Zheng Oncotarget
- Epithelial-mesenchymal transition: potential regulator of ABC transporters in tumor progression
- (2017) Zong-Sheng Jiang et al. Journal of Cancer
- High Expression of MRE11–RAD50–NBS1 Is Associated with Poor Prognosis and Chemoresistance in Gastric Cancer
- (2016) BOLAG LTAN et al. ANTICANCER RESEARCH
- ABC transporters as mediators of drug resistance and contributors to cancer cell biology
- (2016) Jamie I. Fletcher et al. DRUG RESISTANCE UPDATES
- Cancer chemoresistance; biochemical and molecular aspects: a brief overview
- (2016) Saeed Kachalaki et al. EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES
- Approaches for targeting cancer stem cells drug resistance
- (2016) Roberta Rosa et al. Expert Opinion on Drug Discovery
- Natural Polyphenols in Cancer Chemoresistance
- (2016) Saad A. Hussain et al. NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL
- Downregulated DYRK2 expression is associated with poor prognosis and Oxaliplatin resistance in hepatocellular carcinoma
- (2016) Xiubing Zhang et al. PATHOLOGY RESEARCH AND PRACTICE
- Cancer stem cells and chemoresistance: The smartest survives the raid
- (2016) Jihe Zhao PHARMACOLOGY & THERAPEUTICS
- Combination Therapy using Co-encapsulated Resveratrol and Paclitaxel in Liposomes for Drug Resistance Reversal in Breast Cancer Cells in vivo
- (2016) Jie Meng et al. Scientific Reports
- Cisplatin resistance in gastric cancer cells is associated with HER2 upregulation-induced epithelial-mesenchymal transition
- (2016) Dongsheng Huang et al. Scientific Reports
- Resistance to cancer chemotherapy: failure in drug response from ADME to P-gp
- (2015) Khalid O Alfarouk et al. Cancer Cell International
- Evidence Suggesting That Discontinuous Dosing of ALK Kinase Inhibitors May Prolong Control of ALK+ Tumors
- (2015) A. D. Amin et al. CANCER RESEARCH
- Metabolic Mechanisms of Drug Resistance in Leukemia
- (2015) Birgit Knoechel et al. Cell Metabolism
- Overcome Cancer Cell Drug Resistance Using Natural Products
- (2015) Pu Wang et al. Evidence-based Complementary and Alternative Medicine
- Epithelial-mesenchymal transition and drug resistance in breast cancer (Review)
- (2015) JING HUANG et al. INTERNATIONAL JOURNAL OF ONCOLOGY
- Benefits and Harms of Breast Cancer Screening
- (2015) Evan R. Myers et al. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
- Epithelial-to-mesenchymal transition is dispensable for metastasis but induces chemoresistance in pancreatic cancer
- (2015) Xiaofeng Zheng et al. NATURE
- Epithelial-to-mesenchymal transition is not required for lung metastasis but contributes to chemoresistance
- (2015) Kari R. Fischer et al. NATURE
- The emerging role of lncRNAs in cancer
- (2015) Maite Huarte NATURE MEDICINE
- Wnt/β-catenin pathway regulates MGMT gene expression in cancer and inhibition of Wnt signalling prevents chemoresistance
- (2015) Malin Wickström et al. Nature Communications
- Impact of genetic variability and treatment-related factors on outcome in early breast cancer patients receiving (neo-) adjuvant chemotherapy with 5-fluorouracil, epirubicin and cyclophosphamide, and docetaxel
- (2014) C. Vulsteke et al. BREAST CANCER RESEARCH AND TREATMENT
- The Cancer Genome Atlas Research Network: A Sight to Behold
- (2014) Thomas J. Giordano ENDOCRINE PATHOLOGY
- Relationship between RFC gene expression and intracellular drug concentration in methotrexate-resistant osteosarcoma cells
- (2014) J.J. Wang et al. GENETICS AND MOLECULAR RESEARCH
- FOXM1 mediates resistance to docetaxel in gastric cancerviaup-regulating Stathmin
- (2014) Xiaoxiao Li et al. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
- Comprehensive molecular profiling of lung adenocarcinoma
- (2014) Eric A. Collisson et al. NATURE
- Resistance through repopulation
- (2014) Ian F. Tannock NATURE
- Systems biology of cisplatin resistance: past, present and future
- (2014) L Galluzzi et al. Cell Death & Disease
- Drug Resistance in Cancer: An Overview
- (2014) Genevieve Housman et al. Cancers
- Long-term results of dose-dense paclitaxel and carboplatin versus conventional paclitaxel and carboplatin for treatment of advanced epithelial ovarian, fallopian tube, or primary peritoneal cancer (JGOG 3016): a randomised, controlled, open-label trial
- (2013) Noriyuki Katsumata et al. LANCET ONCOLOGY
- Intrinsic and Acquired Drug Resistance in Malignant Tumors
- (2012) Theodor Lippert et al. ARZNEIMITTEL-FORSCHUNG-DRUG RESEARCH
- Taxane resistance in breast cancer: Mechanisms, predictive biomarkers and circumvention strategies
- (2012) S. Murray et al. CANCER TREATMENT REVIEWS
- Current Status of Methods to Assess Cancer Drug Resistance
- (2012) Theodor H. Lippert et al. International Journal of Medical Sciences
- Cancer and Radiation Therapy: Current Advances and Future Directions
- (2012) Rajamanickam Baskar et al. International Journal of Medical Sciences
- Action of bleomycin is affected by bleomycin hydrolase but not by caveolin-1
- (2012) JIANGUO CHEN et al. INTERNATIONAL JOURNAL OF ONCOLOGY
- Nanoparticle Delivery of Cancer Drugs
- (2011) Andrew Z. Wang et al. Annual Review of Medicine
- Recent advances in apoptosis, mitochondria and drug resistance in cancer cells
- (2011) Inthrani R. Indran et al. BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS
- Micromarkers: miRNAs in cancer diagnosis and prognosis
- (2010) Manuela Ferracin et al. EXPERT REVIEW OF MOLECULAR DIAGNOSTICS
- Utility of Incorporating Genetic Variants for the Early Detection of Prostate Cancer
- (2009) R. K. Nam et al. CLINICAL CANCER RESEARCH
- Recent Advances in Cancer Therapy: An Overview
- (2009) A. Urruticoechea et al. CURRENT PHARMACEUTICAL DESIGN
- Label-free detection of DNA mutations by SPR: application to the early detection of inherited breast cancer
- (2008) L. G. Carrascosa et al. ANALYTICAL AND BIOANALYTICAL CHEMISTRY
- Resistance mechanisms to cancer chemotherapy
- (2008) Kelly Marie Redmond Frontiers in Bioscience-Landmark
- 5-Fluorouracil: Mechanisms of Resistance and Reversal Strategies
- (2008) Ning Zhang et al. MOLECULES
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