The role and mechanisms of action of microRNAs in cancer drug resistance
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Title
The role and mechanisms of action of microRNAs in cancer drug resistance
Authors
Keywords
MicroRNAs, Drug resistance, Cancer, Dysregulation, Mechanisms, Chemotherapy
Journal
Clinical Epigenetics
Volume 11, Issue 1, Pages -
Publisher
Springer Nature
Online
2019-02-11
DOI
10.1186/s13148-018-0587-8
References
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Note: Only part of the references are listed.- MicroRNA-195 desensitizes HCT116 human colon cancer cells to 5-fluorouracil
- (2018) Chongtae Kim et al. CANCER LETTERS
- Long noncoding RNA MALAT1 regulates autophagy associated chemoresistance via miR-23b-3p sequestration in gastric cancer
- (2017) Hu YiRen et al. Molecular Cancer
- MiR-183 overexpression inhibits tumorigenesis and enhances DDP-induced cytotoxicity by targeting MTA1 in nasopharyngeal carcinoma
- (2017) Guanghui Wang et al. TUMOR BIOLOGY
- miR-218-5p restores sensitivity to gemcitabine through PRKCE/MDR1 axis in gallbladder cancer
- (2017) Hui Wang et al. Cell Death & Disease
- miR-3656 expression enhances the chemosensitivity of pancreatic cancer to gemcitabine through modulation of the RHOF/EMT axis
- (2017) Rui-Meng Yang et al. Cell Death & Disease
- Involvement of miR-451 in resistance to paclitaxel by regulating YWHAZ in breast cancer
- (2017) Wenrui Wang et al. Cell Death & Disease
- MiR-26 enhances chemosensitivity and promotes apoptosis of hepatocellular carcinoma cells through inhibiting autophagy
- (2017) Fangfang Jin et al. Cell Death & Disease
- MicroRNA-130b targets PTEN to mediate drug resistance and proliferation of breast cancer cells via the PI3K/Akt signaling pathway
- (2017) Yuan Miao et al. Scientific Reports
- Emerging Role of microRNA in Neuropathic Pain
- (2016) Pu Jiangpan et al. CURRENT DRUG METABOLISM
- Epigenetic silencing of miR-137 induces drug resistance and chromosomal instability by targeting AURKA in multiple myeloma
- (2016) Y Qin et al. LEUKEMIA
- Erratum: MicroRNA-587 antagonizes 5-FU-induced apoptosis and confers drug resistance by regulating PPP2R1B expression in colorectal cancer
- (2016) Y Zhang et al. Cell Death & Disease
- Decreased expression of microRNA-17 and microRNA-20b promotes breast cancer resistance to taxol therapy by upregulation of NCOA3
- (2016) Xiang Ao et al. Cell Death & Disease
- Epigenetic mechanisms and therapeutic targets of chemotherapy resistance in epithelial ovarian cancer
- (2015) Jane Borley et al. ANNALS OF MEDICINE
- miR-340 Reverses Cisplatin Resistance of Hepatocellular Carcinoma Cell Lines by Targeting Nrf2-dependent Antioxidant Pathway
- (2015) Liang Shi et al. Asian Pacific Journal of Cancer Prevention
- PPARγ inhibits ovarian cancer cells proliferation through upregulation of miR-125b
- (2015) Shuang Luo et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- miR-320 enhances the sensitivity of human colon cancer cells to chemoradiotherapy in vitro by targeting FOXM1
- (2015) Lu-Ying Wan et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- miR-218 targets survivin and regulates resistance to chemotherapeutics in breast cancer
- (2015) Yunhui Hu et al. BREAST CANCER RESEARCH AND TREATMENT
- Cancer statistics, 2015
- (2015) Rebecca L. Siegel et al. CA-A CANCER JOURNAL FOR CLINICIANS
- miR-15b regulates cisplatin resistance and metastasis by targeting PEBP4 in human lung adenocarcinoma cells
- (2015) Z Zhao et al. CANCER GENE THERAPY
- MicroRNAs in colorectal cancer: Small molecules with big functions
- (2015) Yu Xuan et al. CANCER LETTERS
- Krüppel-like factor 9 inhibits glioma cell proliferation and tumorigenicity via downregulation of miR-21
- (2015) Shuyun Huang et al. CANCER LETTERS
- MiR-30e induces apoptosis and sensitizes K562 cells to imatinib treatment via regulation of the BCR–ABL protein
- (2015) Oshrat Hershkovitz-Rokah et al. CANCER LETTERS
- miR-27b synergizes with anticancer drugs via p53 activation and CYP1B1 suppression
- (2015) Wenjing Mu et al. CELL RESEARCH
- MiR-141 Activates Nrf2-Dependent Antioxidant Pathway via Down-Regulating the Expression of Keap1 Conferring the Resistance of Hepatocellular Carcinoma Cells to 5-Fluorouracil
- (2015) Liang Shi et al. CELLULAR PHYSIOLOGY AND BIOCHEMISTRY
- A Comprehensive Review on miR-200c, A Promising Cancer Biomarker with Therapeutic Potential
- (2015) Suresh Kumar et al. CURRENT DRUG TARGETS
- miRNA-497 Enhances the Sensitivity of Colorectal Cancer Cells to Neoadjuvant Chemotherapeutic Drug
- (2015) Lin Liu et al. CURRENT PROTEIN & PEPTIDE SCIENCE
- Involvement of miR-133a and miR-326 in ADM resistance of HepG2 through modulating expression of ABCC1
- (2015) Jin Ma et al. JOURNAL OF DRUG TARGETING
- MiR-197 induces Taxol resistance in human ovarian cancer cells by regulating NLK
- (2015) Dongling Zou et al. TUMOR BIOLOGY
- Repression of c-Kit by p53 is mediated by miR-34 and is associated with reduced chemoresistance, migration and stemness
- (2015) Helge Siemens et al. Oncotarget
- Methylation of miR-129-5p CpG island modulates multi-drug resistance in gastric cancer by targeting ABC transporters
- (2015) Qiong Wu et al. Oncotarget
- MiR-489 modulates cisplatin resistance in human ovarian cancer cells by targeting Akt3
- (2014) Huijuan Wu et al. ANTI-CANCER DRUGS
- Indirect modulation of sensitivity to 5-fluorouracil by microRNA-96 in human colorectal cancer cells
- (2014) Sun-Ah Kim et al. ARCHIVES OF PHARMACAL RESEARCH
- MiR-21 Upregulation Induced by Promoter Zone Histone Acetylation is Associated with Chemoresistance to Gemcitabine and Enhanced Malignancy of Pancreatic Cancer Cells
- (2014) Wei-Feng Song et al. Asian Pacific Journal of Cancer Prevention
- Down-regulation of miRNA-452 is Associated with Adriamycin-resistance in Breast Cancer Cells
- (2014) Qing Hu et al. Asian Pacific Journal of Cancer Prevention
- miR-138-5p reverses gefitinib resistance in non-small cell lung cancer cells via negatively regulating G protein-coupled receptor 124
- (2014) Yi Gao et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Higher LRRFIP1 expression in glioblastoma multiforme is associated with better response to teniposide, a type II topoisomerase inhibitor
- (2014) Wei-Qing Li et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Efficacy of gemcitabine conjugated and miRNA-205 complexed micelles for treatment of advanced pancreatic cancer
- (2014) Anupama Mittal et al. BIOMATERIALS
- Hyaluronic acid-chitosan nanoparticles for co-delivery of MiR-34a and doxorubicin in therapy against triple negative breast cancer
- (2014) Xiongwei Deng et al. BIOMATERIALS
- MicroRNA-486 regulates normal erythropoiesis and enhances growth and modulates drug response in CML progenitors
- (2014) L.-S. Wang et al. BLOOD
- MiR-221 promotes trastuzumab-resistance and metastasis in HER2-positive breast cancers by targeting PTEN
- (2014) Xingming Ye et al. BMB Reports
- MicroRNA-21 is a candidate driver gene for 17q23-25 amplification in ovarian clear cell carcinoma
- (2014) Yukihiro Hirata et al. BMC CANCER
- Epigenetic silencing of miR-375 induces trastuzumab resistance in HER2-positive breast cancer by targeting IGF1R
- (2014) Xing-Ming Ye et al. BMC CANCER
- MiR-224 promotes the chemoresistance of human lung adenocarcinoma cells to cisplatin via regulating G1/S transition and apoptosis by targeting p21WAF1/CIP1
- (2014) H Wang et al. BRITISH JOURNAL OF CANCER
- Copy Number Gain of hsa-miR-569 at 3q26.2 Leads to Loss of TP53INP1 and Aggressiveness of Epithelial Cancers
- (2014) Pradeep Chaluvally-Raghavan et al. CANCER CELL
- A Long Noncoding RNA Activated by TGF-β Promotes the Invasion-Metastasis Cascade in Hepatocellular Carcinoma
- (2014) Ji-hang Yuan et al. CANCER CELL
- Restoration of miR-193b sensitizes Hepatitis B virus-associated hepatocellular carcinoma to sorafenib
- (2014) Kai Mao et al. CANCER LETTERS
- MicroRNA-370 suppresses proliferation and promotes endometrioid ovarian cancer chemosensitivity to cDDP by negatively regulating ENG
- (2014) Xiao-Ping Chen et al. CANCER LETTERS
- Targeting of miR34a-NOTCH1 Axis Reduced Breast Cancer Stemness and Chemoresistance
- (2014) E. Y. Park et al. CANCER RESEARCH
- Overexpression of MicroRNA-122 Re-sensitizes 5-FU-Resistant Colon Cancer Cells to 5-FU Through the Inhibition of PKM2 In Vitro and In Vivo
- (2014) Jinxia He et al. CELL BIOCHEMISTRY AND BIOPHYSICS
- Reduced Expression of miRNA-27a Modulates Cisplatin Resistance in Bladder Cancer by Targeting the Cystine/Glutamate Exchanger SLC7A11
- (2014) R. M. Drayton et al. CLINICAL CANCER RESEARCH
- MicroRNA-182 modulates chemosensitivity of human non-small cell lung cancer to cisplatin by targeting PDCD4
- (2014) Fang-ling Ning et al. Diagnostic Pathology
- Zinc finger E-box-binding homeobox 2 (ZEB2) regulated by miR-200b contributes to multi-drug resistance of small cell lung cancer
- (2014) Shun Fang et al. EXPERIMENTAL AND MOLECULAR PATHOLOGY
- Methylation-regulated miR-149 modulates chemoresistance by targeting GlcNAcN-deacetylase/N-sulfotransferase-1 in human breast cancer
- (2014) Dong-Xu He et al. FEBS Journal
- MiR-489 regulates chemoresistance in breast cancer via epithelial mesenchymal transition pathway
- (2014) Li Jiang et al. FEBS LETTERS
- Down-regulation of miR-199b associated with imatinib drug resistance in 9q34.1 deleted BCR/ABL positive CML patients
- (2014) Dolly Joshi et al. GENE
- Upregulated miR-182 increases drug resistance in cisplatin-treated HCC cell by regulating TP53INP1
- (2014) Jun Qin et al. GENE
- The inhibition of miR-21 promotes apoptosis and chemosensitivity in ovarian cancer
- (2014) John K. Chan et al. GYNECOLOGIC ONCOLOGY
- miR-145 sensitizes ovarian cancer cells to paclitaxel by targeting Sp1 and Cdk6
- (2014) Xiaolan Zhu et al. INTERNATIONAL JOURNAL OF CANCER
- The sensitivity of gastric cancer to trastuzumab is regulated by the miR-223/FBXW7 pathway
- (2014) Kojiro Eto et al. INTERNATIONAL JOURNAL OF CANCER
- MiR-200c suppresses TGF-β signaling and counteracts trastuzumab resistance and metastasis by targeting ZNF217 and ZEB1 in breast cancer
- (2014) Wen-Dong Bai et al. INTERNATIONAL JOURNAL OF CANCER
- MicroRNA-200 (miR-200) Cluster Regulation by Achaete Scute-like 2 (Ascl2)
- (2014) Yin Tian et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- MicroRNAs: master regulators of drug resistance, stemness, and metastasis
- (2014) Umar Raza et al. JOURNAL OF MOLECULAR MEDICINE-JMM
- MicroRNA-26b suppresses the NF-κB signaling and enhances the chemosensitivity of hepatocellular carcinoma cells by targeting TAK1 and TAB3
- (2014) Na Zhao et al. Molecular Cancer
- miR-27a regulates cisplatin resistance and metastasis by targeting RKIP in human lung adenocarcinoma cells
- (2014) Jipeng Li et al. Molecular Cancer
- Pseudogene PTENP1 Functions as a Competing Endogenous RNA to Suppress Clear-Cell Renal Cell Carcinoma Progression
- (2014) G. Yu et al. MOLECULAR CANCER THERAPEUTICS
- Endogenous miRNA and Target Concentrations Determine Susceptibility to Potential ceRNA Competition
- (2014) Andrew D. Bosson et al. MOLECULAR CELL
- MicroRNA-106a confers cisplatin resistance in non-small cell lung cancer A549 cells by targeting adenosine triphosphatase-binding cassette A1
- (2014) YANXIN MA et al. Molecular Medicine Reports
- Overexpression of microRNA-125b sensitizes human hepatocellular carcinoma cells to 5-fluorouracil through inhibition of glycolysis by targeting hexokinase II
- (2014) JIAN-XIN JIANG et al. Molecular Medicine Reports
- miR-203 enhances chemosensitivity to 5-fluorouracil by targeting thymidylate synthase in colorectal cancer
- (2014) TAO LI et al. ONCOLOGY REPORTS
- Up-Regulation of MicroRNA-190b Plays a Role for Decreased IGF-1 That Induces Insulin Resistance in Human Hepatocellular Carcinoma
- (2014) Tzu-Min Hung et al. PLoS One
- miR-17-5p Downregulation Contributes to Paclitaxel Resistance of Lung Cancer Cells through Altering Beclin1 Expression
- (2014) Abhisek Chatterjee et al. PLoS One
- MiR-338-3p Inhibits Hepatocarcinoma Cells and Sensitizes These Cells to Sorafenib by Targeting Hypoxia-Induced Factor 1α
- (2014) Haitao Xu et al. PLoS One
- MicroRNA-449a reduces cell survival and enhances cisplatin-induced cytotoxicity via downregulation of NOTCH1 in ovarian cancer cells
- (2014) Yanqi Zhou et al. TUMOR BIOLOGY
- miR-101 regulates expression of EZH2 and contributes to progression of and cisplatin resistance in epithelial ovarian cancer
- (2014) Lin Liu et al. TUMOR BIOLOGY
- MicroRNA-100 regulates pancreatic cancer cells growth and sensitivity to chemotherapy through targeting FGFR3
- (2014) Zhipeng Li et al. TUMOR BIOLOGY
- Downregulation of PEBP4, a target of miR-34a, sensitizes drug-resistant lung cancer cells
- (2014) Guiping Yu et al. TUMOR BIOLOGY
- Downregulation of miR-130a contributes to cisplatin resistance in ovarian cancer cells by targeting X-linked inhibitor of apoptosis (XIAP) directly
- (2013) X. Zhang et al. ACTA BIOCHIMICA ET BIOPHYSICA SINICA
- Friend or foe: the role of microRNA in chemotherapy resistance
- (2013) Haoran Li et al. ACTA PHARMACOLOGICA SINICA
- The MicroRNA-21/PTEN Pathway Regulates the Sensitivity of HER2-Positive Gastric Cancer Cells to Trastuzumab
- (2013) Kojiro Eto et al. ANNALS OF SURGICAL ONCOLOGY
- MiR-92b regulates the cell growth, cisplatin chemosensitivity of A549 non small cell lung cancer cell line and target PTEN
- (2013) Yan Li et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- miR-320c regulates gemcitabine-resistance in pancreatic cancer via SMARCC1
- (2013) Y Iwagami et al. BRITISH JOURNAL OF CANCER
- Dysregulation of miR-106a and miR-591 confers paclitaxel resistance to ovarian cancer
- (2013) J H Huh et al. BRITISH JOURNAL OF CANCER
- MiR-487a resensitizes mitoxantrone (MX)-resistant breast cancer cells (MCF-7/MX) to MX by targeting breast cancer resistance protein (BCRP/ABCG2)
- (2013) Meng-Tao Ma et al. CANCER LETTERS
- MicroRNA-31 inhibits cisplatin-induced apoptosis in non-small cell lung cancer cells by regulating the drug transporter ABCB9
- (2013) Zhuo Dong et al. CANCER LETTERS
- miR-153 Supports Colorectal Cancer Progression via Pleiotropic Effects That Enhance Invasion and Chemotherapeutic Resistance
- (2013) L. Zhang et al. CANCER RESEARCH
- The Function Role of miR-181a in Chemosensitivity to Adriamycin by Targeting Bcl-2 in Low-Invasive Breast Cancer Cells
- (2013) Ying Zhu et al. CELLULAR PHYSIOLOGY AND BIOCHEMISTRY
- MicroRNAs as therapeutic targets in chemoresistance
- (2013) Michela Garofalo et al. DRUG RESISTANCE UPDATES
- MiR-223 modulates multidrug resistance via downregulation of ABCB1 in hepatocellular carcinoma cells
- (2013) Tao Yang et al. EXPERIMENTAL BIOLOGY AND MEDICINE
- MicroRNA-181a enhances the chemoresistance of human cervical squamous cell carcinoma to cisplatin by targeting PRKCD
- (2013) Yiran Chen et al. EXPERIMENTAL CELL RESEARCH
- MiR-214 reduces cell survival and enhances cisplatin-induced cytotoxicity via down-regulation of Bcl2l2 in cervical cancer cells
- (2013) Fang Wang et al. FEBS LETTERS
- MicroRNA-216a/217-induced epithelial-mesenchymal transition targets PTEN and SMAD7 to promote drug resistance and recurrence of liver cancer
- (2013) Hongping Xia et al. HEPATOLOGY
- miR-503 regulates the resistance of non-small cell lung cancer cells to cisplatin by targeting Bcl-2
- (2013) TIANZHU QIU et al. INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE
- The Overexpression of Hypomethylated miR-663 Induces Chemotherapy Resistance in Human Breast Cancer Cells by Targeting Heparin Sulfate Proteoglycan 2 (HSPG2)
- (2013) Haiyan Hu et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- MicroRNA-23a Antisense Enhances 5-Fluorouracil Chemosensitivity Through APAF-1/Caspase-9 Apoptotic Pathway in Colorectal Cancer Cells
- (2013) Jingli Shang et al. JOURNAL OF CELLULAR BIOCHEMISTRY
- MicroRNA-195 Chemosensitizes Colon Cancer Cells to the Chemotherapeutic Drug Doxorubicin by Targeting the First Binding Site of BCL2L2 mRNA
- (2013) Juan Qu et al. JOURNAL OF CELLULAR PHYSIOLOGY
- Progress in microRNA delivery
- (2013) Yu Zhang et al. JOURNAL OF CONTROLLED RELEASE
- MiR-106a targets Mcl-1 to suppress cisplatin resistance of ovarian cancer A2780 cells
- (2013) Yu-mei Rao et al. Journal of Huazhong University of Science and Technology-Medical Sciences
- miR-9 Regulation of BRCA1 and Ovarian Cancer Sensitivity to Cisplatin and PARP Inhibition
- (2013) Chaoyang Sun et al. JNCI-Journal of the National Cancer Institute
- MiR-134/487b/655 Cluster Regulates TGF- -Induced Epithelial-Mesenchymal Transition and Drug Resistance to Gefitinib by Targeting MAGI2 in Lung Adenocarcinoma Cells
- (2013) K. Kitamura et al. MOLECULAR CANCER THERAPEUTICS
- miR-203 induces oxaliplatin resistance in colorectal cancer cells by negatively regulating ATM kinase
- (2013) Yunfei Zhou et al. Molecular Oncology
- miR-205 promotes the growth, metastasis and chemoresistance of NSCLC cells by targeting PTEN
- (2013) LIN LEI et al. ONCOLOGY REPORTS
- miR-200b suppresses cell proliferation, migration and enhances chemosensitivity in prostate cancer by regulating Bmi-1
- (2013) JUNJIE YU et al. ONCOLOGY REPORTS
- Upregulation of miR-195 increases the sensitivity of breast cancer cells to Adriamycin treatment through inhibition of Raf-1
- (2013) GE YANG et al. ONCOLOGY REPORTS
- MicroRNA-200c Regulates the Sensitivity of Chemotherapy of Gastric Cancer SGC7901/DDP Cells by Directly Targeting RhoE
- (2013) Liang Chang et al. PATHOLOGY & ONCOLOGY RESEARCH
- miR-135a/b Modulate Cisplatin Resistance of Human Lung Cancer Cell Line by Targeting MCL1
- (2013) Li Zhou et al. PATHOLOGY & ONCOLOGY RESEARCH
- Concordant and Discordant Regulation of Target Genes by miR-31 and Its Isoforms
- (2013) Yu-Tzu Chan et al. PLoS One
- cMyc/miR-125b-5p Signalling Determines Sensitivity to Bortezomib in Preclinical Model of Cutaneous T-Cell Lymphomas
- (2013) Valentina Manfè et al. PLoS One
- Reduced Expression of miR-200 Family Members Contributes to Antiestrogen Resistance in LY2 Human Breast Cancer Cells
- (2013) Tissa T. Manavalan et al. PLoS One
- Inhibition of BCR/ABL Protein Expression by miR-203 Sensitizes for Imatinib Mesylate
- (2013) Yajuan Li et al. PLoS One
- MicroRNA-650 Was a Prognostic Factor in Human Lung Adenocarcinoma and Confers the Docetaxel Chemoresistance of Lung Adenocarcinoma Cells via Regulating Bcl-2/Bax Expression
- (2013) Jia-Yuan Huang et al. PLoS One
- MicroRNA-34a Targets Bcl-2 and Sensitizes Human Hepatocellular Carcinoma Cells to Sorafenib Treatment
- (2013) Fan Yang et al. TECHNOLOGY IN CANCER RESEARCH & TREATMENT
- microRNA-106a modulates cisplatin sensitivity by targeting PDCD4 in human ovarian cancer cells
- (2013) HAO LI et al. Oncology Letters
- ceRNA Cross-Talk in Cancer: When ce-bling Rivalries Go Awry
- (2013) F. A. Karreth et al. Cancer Discovery
- Deregulation of let-7e in epithelial ovarian cancer promotes the development of resistance to cisplatin
- (2013) J Cai et al. Oncogenesis
- Downregulation of miRNA-31 induces taxane resistance in ovarian cancer cells through increase of receptor tyrosine kinase MET
- (2013) T Mitamura et al. Oncogenesis
- miR-137 restoration sensitizes multidrug-resistant MCF-7/ADM cells to anticancer agents by targeting YB-1
- (2012) X. Zhu et al. ACTA BIOCHIMICA ET BIOPHYSICA SINICA
- miR-181a sensitizes a multidrug-resistant leukemia cell line K562/A02 to daunorubicin by targeting BCL-2
- (2012) H. Li et al. ACTA BIOCHIMICA ET BIOPHYSICA SINICA
- miR-126 enhances the sensitivity of non-small cell lung cancer cells to anticancer agents by targeting vascular endothelial growth factor A
- (2012) X. Zhu et al. ACTA BIOCHIMICA ET BIOPHYSICA SINICA
- Increased Expression of P-Glycoprotein and Doxorubicin Chemoresistance of Metastatic Breast Cancer Is Regulated by miR-298
- (2012) Lili Bao et al. AMERICAN JOURNAL OF PATHOLOGY
- MicroRNA-10b is a Prognostic Indicator in Colorectal Cancer and Confers Resistance to the Chemotherapeutic Agent 5-Fluorouracil in Colorectal Cancer Cells
- (2012) Naohiro Nishida et al. ANNALS OF SURGICAL ONCOLOGY
- Upregulated miR-130a increases drug resistance by regulating RUNX3 and Wnt signaling in cisplatin-treated HCC cell
- (2012) Ning Xu et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Cisplatin-induced downregulation of miR-199a-5p increases drug resistance by activating autophagy in HCC cell
- (2012) Ning Xu et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- MiR-96 Downregulates REV1 and RAD51 to Promote Cellular Sensitivity to Cisplatin and PARP Inhibition
- (2012) Yemin Wang et al. CANCER RESEARCH
- Cancer Epigenetics: From Mechanism to Therapy
- (2012) Mark A. Dawson et al. CELL
- An anti-let-7 sponge decoys and decays endogenous let-7 functions
- (2012) Xiangling Yang et al. CELL CYCLE
- Involvement of microRNA-93, a new regulator of PTEN/Akt signaling pathway, in regulation of chemotherapeutic drug cisplatin chemosensitivity in ovarian cancer cells
- (2012) Xin Fu et al. FEBS LETTERS
- Recent Insights and Novel Bioinformatics Tools to Understand the Role of MicroRNAs Binding to 5' Untranslated Region
- (2012) Letizia Sacco et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- The p63 Protein Isoform ΔNp63α Inhibits Epithelial-Mesenchymal Transition in Human Bladder Cancer Cells
- (2012) Mai N. Tran et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- miR-513a-3p sensitizes human lung adenocarcinoma cells to chemotherapy by targeting GSTP1
- (2012) Xuelin Zhang et al. LUNG CANCER
- Restoration of miR-200c to Ovarian Cancer Reduces Tumor Burden and Increases Sensitivity to Paclitaxel
- (2012) D. M. Cittelly et al. MOLECULAR CANCER THERAPEUTICS
- microRNAs as tumor inhibitors, oncogenes, biomarkers for drug efficacy and outcome predictors in lung cancer (Review)
- (2012) YAN-WEN JIANG et al. Molecular Medicine Reports
- The serum miR-21 level serves as a predictor for the chemosensitivity of advanced pancreatic cancer, and miR-21 expression confers chemoresistance by targeting FasL
- (2012) Peng Wang et al. Molecular Oncology
- Systemically Injected Exosomes Targeted to EGFR Deliver Antitumor MicroRNA to Breast Cancer Cells
- (2012) Shin-ichiro Ohno et al. MOLECULAR THERAPY
- Treatment-induced damage to the tumor microenvironment promotes prostate cancer therapy resistance through WNT16B
- (2012) Yu Sun et al. NATURE MEDICINE
- miR-34c may protect lung cancer cells from paclitaxel-induced apoptosis
- (2012) S Catuogno et al. ONCOGENE
- Re-expression of microRNA-375 reverses both tamoxifen resistance and accompanying EMT-like properties in breast cancer
- (2012) A Ward et al. ONCOGENE
- Altered microRNA expression in cisplatin-resistant ovarian cancer cells and upregulation of miR-130a associated with MDR1/P-glycoprotein-mediated drug resistance
- (2012) LINGYUN YANG et al. ONCOLOGY REPORTS
- Lentiviral Transgenic MicroRNA-Based shRNA Suppressed Mouse Cytochromosome P450 3A (CYP3A) Expression in a Dose-Dependent and Inheritable Manner
- (2012) Yong Wang et al. PLoS One
- Circulating MiR-125b as a Marker Predicting Chemoresistance in Breast Cancer
- (2012) Hongjiang Wang et al. PLoS One
- Let-7b Inhibits Human Cancer Phenotype by Targeting Cytochrome P450 Epoxygenase 2J2
- (2012) Fuqiong Chen et al. PLoS One
- miR-337-3p and Its Targets STAT3 and RAP1A Modulate Taxane Sensitivity in Non-Small Cell Lung Cancers
- (2012) Liqin Du et al. PLoS One
- miR-200c Sensitizes Breast Cancer Cells to Doxorubicin Treatment by Decreasing TrkB and Bmi1 Expression
- (2012) Florian Kopp et al. PLoS One
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- (2011) H. Chai et al. ACTA BIOCHIMICA ET BIOPHYSICA SINICA
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- (2011) Zhao-Xia Wang et al. ARCHIVES OF MEDICAL RESEARCH
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- (2011) L. Kastl et al. BREAST CANCER RESEARCH AND TREATMENT
- MicroRNA-200b reverses chemoresistance of docetaxel-resistant human lung adenocarcinoma cells by targeting E2F3
- (2011) Bing Feng et al. CANCER
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- (2011) Wei Zhu et al. CANCER CHEMOTHERAPY AND PHARMACOLOGY
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- (2011) Bing Feng et al. CANCER LETTERS
- A ceRNA Hypothesis: The Rosetta Stone of a Hidden RNA Language?
- (2011) Leonardo Salmena et al. CELL
- Molecular mechanisms underlying the role of microRNAs (miRNAs) in anticancer drug resistance and implications for clinical practice
- (2011) Elisa Giovannetti et al. CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY
- Alterations of microRNAs in Cisplatin-resistant Human Non-small Cell Lung Cancer Cells (A549/DDP)
- (2011) Qi Wang et al. EXPERIMENTAL LUNG RESEARCH
- Epigenetic silencing of miR-130b in ovarian cancer promotes the development of multidrug resistance by targeting colony-stimulating factor 1
- (2011) Chun Yang et al. GYNECOLOGIC ONCOLOGY
- Let-7 modulates acquired resistance of ovarian cancer to Taxanes via IMP-1-mediated stabilization of multidrug resistance 1
- (2011) Benjamin Boyerinas et al. INTERNATIONAL JOURNAL OF CANCER
- Nucleolin Protein Interacts with Microprocessor Complex to Affect Biogenesis of MicroRNAs 15a and 16
- (2011) Brian F. Pickering et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- MicroRNA-30a Sensitizes Tumor Cells to cis-Platinum via Suppressing Beclin 1-mediated Autophagy
- (2011) Zhenyou Zou et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- DNA Methylation-regulated miR-193a-3p Dictates Resistance of Hepatocellular Carcinoma to 5-Fluorouracil via Repression of SRSF2 Expression
- (2011) Kelong Ma et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- miRNA-205 Suppresses Melanoma Cell Proliferation and Induces Senescence via Regulation of E2F1 Protein
- (2011) Altaf A. Dar et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Up-regulation ofmiR-21Mediates Resistance to Trastuzumab Therapy for Breast Cancer
- (2011) Chang Gong et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- A microRNA-dependent program controls p53-independent survival and chemosensitivity in human and murine squamous cell carcinoma
- (2011) Benjamin Ory et al. JOURNAL OF CLINICAL INVESTIGATION
- MicroRNA-141 confers resistance to cisplatin-induced apoptosis by targeting YAP1 in human esophageal squamous cell carcinoma
- (2011) Yukako Imanaka et al. JOURNAL OF HUMAN GENETICS
- The miRNA-17∼92 cluster mediates chemoresistance and enhances tumor growth in mantle cell lymphoma via PI3K/AKT pathway activation
- (2011) E Rao et al. LEUKEMIA
- miR-107 targets cyclin-dependent kinase 6 expression, induces cell cycle G1 arrest and inhibits invasion in gastric cancer cells
- (2011) Li Feng et al. MEDICAL ONCOLOGY
- miR-143 decreases prostate cancer cells proliferation and migration and enhances their sensitivity to docetaxel through suppression of KRAS
- (2011) Bin Xu et al. MOLECULAR AND CELLULAR BIOCHEMISTRY
- Upregulation of microRNA-125b contributes to leukemogenesis and increases drug resistance in pediatric acute promyelocytic leukemia
- (2011) Hua Zhang et al. Molecular Cancer
- miR-1915 inhibits Bcl-2 to modulate multidrug resistance by increasing drug-sensitivity in human colorectal carcinoma cells
- (2011) Ke Xu et al. MOLECULAR CARCINOGENESIS
- PTEN Modulates miR-21 Processing via RNA-Regulatory Protein RNH1
- (2011) Youn-Jae Kim et al. PLoS One
- Small molecule enoxacin is a cancer-specific growth inhibitor that acts by enhancing TAR RNA-binding protein 2-mediated microRNA processing
- (2011) S. Melo et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- MicroRNA-451 Is Involved in the Self-renewal, Tumorigenicity, and Chemoresistance of Colorectal Cancer Stem Cells
- (2011) Nerea Bitarte et al. STEM CELLS
- DNA methylation of tumor suppressor miRNA genes: a lesson from themiR-34family
- (2011) Kwan Yeung Wong et al. Epigenomics
- MicroRNA-mediated drug resistance in breast cancer
- (2011) Kristy R. Kutanzi et al. Clinical Epigenetics
- microRNA expression profile and identification of miR-29 as a prognostic marker and pathogenetic factor by targeting CDK6 in mantle cell lymphoma
- (2010) J.-J. Zhao et al. BLOOD
- Cancer Statistics, 2010
- (2010) A. Jemal et al. CA-A CANCER JOURNAL FOR CLINICIANS
- MicroRNA and drug resistance
- (2010) J Ma et al. CANCER GENE THERAPY
- MiR-199a-3p Regulates mTOR and c-Met to Influence the Doxorubicin Sensitivity of Human Hepatocarcinoma Cells
- (2010) Francesca Fornari et al. CANCER RESEARCH
- Oncogenic HER2Δ16 suppresses miR-15a/16 and deregulates BCL-2 to promote endocrine resistance of breast tumors
- (2010) Diana M. Cittelly et al. CARCINOGENESIS
- Inactivation of miR-34a by aberrant CpG methylation in multiple types of cancer
- (2010) Dmitri Lodygin et al. CELL CYCLE
- Alterations of microRNAs and their targets are associated with acquired resistance of MCF-7 breast cancer cells to cisplatin
- (2010) Igor P. Pogribny et al. INTERNATIONAL JOURNAL OF CANCER
- miR-181b modulates multidrug resistance by targeting BCL2 in human cancer cell lines
- (2010) Wei Zhu et al. INTERNATIONAL JOURNAL OF CANCER
- MiR-148a Attenuates Paclitaxel Resistance of Hormone-refractory, Drug-resistant Prostate Cancer PC3 Cells by Regulating MSK1 Expression
- (2010) Yasunori Fujita et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- MicroRNA-155Regulates Cell Survival, Growth, and Chemosensitivity by TargetingFOXO3ain Breast Cancer
- (2010) William Kong et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Multiple Drug Resistance Mechanisms in Cancer
- (2010) Bruce C. Baguley MOLECULAR BIOTECHNOLOGY
- Resistance May Not Be Futile: microRNA Biomarkers for Chemoresistance and Potential Therapeutics
- (2010) K. E. Allen et al. MOLECULAR CANCER THERAPEUTICS
- Multiple microRNAs modulate p21Cip1/Waf1 expression by directly targeting its 3′ untranslated region
- (2010) S Wu et al. ONCOGENE
- MicroRNA-21 induces resistance to 5-fluorouracil by down-regulating human DNA MutS homolog 2 (hMSH2)
- (2010) N. Valeri et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- MiR-34a attenuates paclitaxel-resistance of hormone-refractory prostate cancer PC3 cells through direct and indirect mechanisms
- (2010) Keitaro Kojima et al. PROSTATE
- miR-34a as a prognostic marker of relapse in surgically resected non-small-cell lung cancer
- (2009) Elena Gallardo et al. CARCINOGENESIS
- Hyaluronan-CD44 Interaction with Protein Kinase Cϵ Promotes Oncogenic Signaling by the Stem Cell Marker Nanog and the Production of MicroRNA-21, Leading to Down-regulation of the Tumor Suppressor Protein PDCD4, Anti-apoptosis, and Chemotherapy Resistance in Breast Tumor Cells
- (2009) Lilly Y. W. Bourguignon et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- MicroRNAs in Cancer: Small Molecules With a Huge Impact
- (2009) Marilena V. Iorio et al. JOURNAL OF CLINICAL ONCOLOGY
- MicroRNA-200c mitigates invasiveness and restores sensitivity to microtubule-targeting chemotherapeutic agents
- (2009) D. R. Cochrane et al. MOLECULAR CANCER THERAPEUTICS
- MicroRNA-328 Negatively Regulates the Expression of Breast Cancer Resistance Protein (BCRP/ABCG2) in Human Cancer Cells
- (2009) Y.-Z. Pan et al. MOLECULAR PHARMACOLOGY
- High-Dose Daunorubicin in Older Patients with Acute Myeloid Leukemia
- (2009) Bob Löwenberg et al. NEW ENGLAND JOURNAL OF MEDICINE
- Loss of miR-200c: A Marker of Aggressiveness and Chemoresistance in Female Reproductive Cancers
- (2009) Dawn R. Cochrane et al. Journal of Oncology
- MIRN199Bdownregulation in chronic myeloid leukaemia is associated with deletions on der(9)
- (2008) Francesco Albano et al. BRITISH JOURNAL OF HAEMATOLOGY
- MicroRNA Expression Profiling in Human Ovarian Cancer: miR-214 Induces Cell Survival and Cisplatin Resistance by Targeting PTEN
- (2008) H. Yang et al. CANCER RESEARCH
- Post-transcriptional Regulation of Human Pregnane X Receptor by Micro-RNA Affects the Expression of Cytochrome P450 3A4
- (2008) Shingo Takagi et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- MicroRNA-221/222 Negatively Regulates Estrogen Receptorα and Is Associated with Tamoxifen Resistance in Breast Cancer
- (2008) Jian-Jun Zhao et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Intrinsic Resistance of Tumorigenic Breast Cancer Cells to Chemotherapy
- (2008) X. Li et al. JNCI-Journal of the National Cancer Institute
- MicroRNA-155 Is Regulated by the Transforming Growth Factor /Smad Pathway and Contributes to Epithelial Cell Plasticity by Targeting RhoA
- (2008) W. Kong et al. MOLECULAR AND CELLULAR BIOLOGY
- Involvement of microRNA-451 in resistance of the MCF-7 breast cancer cells to chemotherapeutic drug doxorubicin
- (2008) O. Kovalchuk et al. MOLECULAR CANCER THERAPEUTICS
- Widespread changes in protein synthesis induced by microRNAs
- (2008) Matthias Selbach et al. NATURE
- miR-16 family induces cell cycle arrest by regulating multiple cell cycle genes
- (2008) Q. Liu et al. NUCLEIC ACIDS RESEARCH
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