Doxorubicin suppresses chondrocyte differentiation by stimulating ROS production

The Role of Chondrocyte Hypertrophy and Senescence in Osteoarthritis Initiation and Progression

(2020) Yeri Alice Rim et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Co-delivery of a RanGTP inhibitory peptide and doxorubicin using dual loaded liposomal carriers to combat chemotherapeutic resistance in breast cancer cells

(2020) Yusuf Haggag et al.   Expert Opinion on Drug Delivery

Anti-inflammatory capacity of Apremilast in human chondrocytes is dependent on SOX-9

(2020) Yanjie Zhang et al.   INFLAMMATION RESEARCH

Mechanisms and therapeutic implications of cellular senescence in osteoarthritis

(2020) Philip R. Coryell et al.   Nature Reviews Rheumatology

Oxidative Stress: A Key Modulator in Neurodegenerative Diseases

(2019) Anju Singh et al.   MOLECULES

Oxidative stress injury in doxorubicin-induced cardiotoxicity

(2019) Mei Songbo et al.   TOXICOLOGY LETTERS

FAM122A supports the growth of hepatocellular carcinoma cells and its deletion enhances Doxorubicin-induced cytotoxicity

(2019) Yong Zhou et al.   EXPERIMENTAL CELL RESEARCH

Targeting β-catenin dependent Wnt signaling via peptidomimetic inhibitors in murine chondrocytes and OA cartilage

(2018) A. Held et al.   OSTEOARTHRITIS AND CARTILAGE

A small-molecule inhibitor of the Wnt pathway (SM04690) as a potential disease modifying agent for the treatment of osteoarthritis of the knee

(2018) V. Deshmukh et al.   OSTEOARTHRITIS AND CARTILAGE

Parkin clearance of dysfunctional mitochondria regulates ROS levels and increases survival of human chondrocytes

(2018) M.Y. Ansari et al.   OSTEOARTHRITIS AND CARTILAGE

Osteoarthritis induced by destabilization of the medial meniscus is reduced in germ-free mice

(2018) V. Ulici et al.   OSTEOARTHRITIS AND CARTILAGE

Redox and NF-κB signaling in osteoarthritis

(2018) Panagiotis Lepetsos et al.   FREE RADICAL BIOLOGY AND MEDICINE

Mesenchymal stem cell-based therapy of osteoarthritis: Current knowledge and future perspectives

(2018) C. Randall Harrell et al.   BIOMEDICINE & PHARMACOTHERAPY

Redox control of chondrocyte differentiation and chondrogenesis

(2018) Yun Bai et al.   FREE RADICAL BIOLOGY AND MEDICINE

ROS homeostasis, a key determinant in liver ischemic-preconditioning

(2017) Ignacio Prieto et al.   Redox Biology

Doxorubicin-induced oxidative stress: The protective effect of nicorandil on HL-1 cardiomyocytes

(2017) Mari C. Asensio-López et al.   PLoS One

Isolation and characterization of primary bone marrow mesenchymal stromal cells

(2016) Hongzhe Li et al.   Annals of the New York Academy of Sciences

Molecular mechanisms of ROS production and oxidative stress in diabetes

(2016) P. Newsholme et al.   BIOCHEMICAL JOURNAL

SOX9 and the many facets of its regulation in the chondrocyte lineage

(2016) Véronique Lefebvre et al.   CONNECTIVE TISSUE RESEARCH

Reactive Oxygen Species Affect Transglutaminase Activity and Regulate Hematopoiesis in a Crustacean

(2016) Kingkamon Junkunlo et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Osteoarthritis

(2016) Johanne Martel-Pelletier et al.   Nature Reviews Disease Primers

Osteoarthritis

(2015) S Glyn-Jones et al.   LANCET

An overview of doxorubicin formulations in cancer therapy

(2015) Sangeeta Rivankar   Journal of Cancer Research and Therapeutics

The thymoquinone-induced production of reactive oxygen species promotes dedifferentiation through the ERK pathway and inflammation through the p38 and PI3K pathways in rabbit articular chondrocytes

(2014) SEON-MI YU et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

Withaferin A-Caused Production of Intracellular Reactive Oxygen Species Modulates Apoptosis via PI3K/Akt and JNKinase in Rabbit Articular Chondrocytes

(2014) Seon-Mi Yu et al.   JOURNAL OF KOREAN MEDICAL SCIENCE

Diagnosis and Treatment of Osteoarthritis

(2013) Rafaelani L. Taruc-Uy et al.   PRIMARY CARE

17β-Oestradiol inhibits doxorubicin-induced apoptosis via block of the volume-sensitive Cl- current in rabbit articular chondrocytes

(2011) Kousuke Kumagai et al.   BRITISH JOURNAL OF PHARMACOLOGY

Possibilities to increase the effectiveness of doxorubicin in cancer cells killing

(2011) Veronika Hanušová et al.   DRUG METABOLISM REVIEWS

Oxidative Stress Inhibits Insulin-like Growth Factor-I Induction of Chondrocyte Proteoglycan Synthesis through Differential Regulation of Phosphatidylinositol 3-Kinase-Akt and MEK-ERK MAPK Signaling Pathways

(2009) Weihong Yin et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Osteoarthritis in the context of ageing and evolution

(2007) Peter M. van der Kraan et al.   AGEING RESEARCH REVIEWS