Self-nonself discrimination by the complement system

Disturbed sialic acid recognition on endothelial cells and platelets in complement attack causes atypical hemolytic uremic syndrome

(2016) S. Hyvarinen et al.   BLOOD

The pathobiology of pig-to-primate xenotransplantation: a historical review

(2016) David K.C. Cooper et al.   XENOTRANSPLANTATION

SALSA: A Regulator of the Early Steps of Complement Activation on Mucosal Surfaces

(2016) Martin Parnov Reichhardt et al.   Frontiers in Immunology

The evolution of natural killer cell receptors

(2015) Paola Carrillo-Bustamante et al.   IMMUNOGENETICS

The Major Autoantibody Epitope on Factor H in Atypical Hemolytic Uremic Syndrome Is Structurally Different from Its Homologous Site in Factor H-related Protein 1, Supporting a Novel Model for Induction of Autoimmunity in This Disease

(2015) Arnab Bhattacharjee et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Binding of the Long Pentraxin PTX3 to Factor H: Interacting Domains and Function in the Regulation of Complement Activation

(2014) L. Deban et al.   JOURNAL OF IMMUNOLOGY

The Salivary Scavenger and Agglutinin in Early Life: Diverse Roles in Amniotic Fluid and in the Infant Intestine

(2014) Martin Parnov Reichhardt et al.   JOURNAL OF IMMUNOLOGY

Structural basis for sialic acid–mediated self-recognition by complement factor H

(2014) Bärbel S Blaum et al.   Nature Chemical Biology

Genetics of Atypical Hemolytic Uremic Syndrome (aHUS)

(2014) Marta Hidalgo et al.   SEMINARS IN THROMBOSIS AND HEMOSTASIS

Role of Complement in Enterohemorrhagic Escherichia coli–Induced Hemolytic Uremic Syndrome

(2014) Reinhard Würzner et al.   SEMINARS IN THROMBOSIS AND HEMOSTASIS

Competition between antagonistic complement factors for a single protein on N. meningitidis rules disease susceptibility

(2014) Joseph JE Caesar et al.   eLife

Monocyte Expressed Macromolecular C1 and C1q Receptors as Molecular Sensors of Danger: Implications in SLE

(2014) Berhane Ghebrehiwet et al.   Frontiers in Immunology

Deciphering the Fine Details of C1 Assembly and Activation Mechanisms: “Mission Impossible”?

(2014) Christine Gaboriaud et al.   Frontiers in Immunology

Complement Activation and Regulation in Preeclamptic Placenta

(2014) Anna Inkeri Lokki et al.   Frontiers in Immunology

Thrombosis in paroxysmal nocturnal hemoglobinuria

(2013) A. Hill et al.   BLOOD

Complement activation in diseases presenting with thrombotic microangiopathy

(2013) Seppo Meri   European Journal of Internal Medicine

C3 glomerulopathy–associated CFHR1 mutation alters FHR oligomerization and complement regulation

(2013) Agustín Tortajada et al.   JOURNAL OF CLINICAL INVESTIGATION

Complement Factor H: A Biomarker for Progression of Cutaneous Squamous Cell Carcinoma

(2013) Pilvi M. Riihilä et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Dimerization of complement factor H-related proteins modulates complement activation in vivo

(2013) E. Goicoechea de Jorge et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Metabolic function of the CTRP family of hormones

(2013) Marcus M. Seldin et al.   REVIEWS IN ENDOCRINE & METABOLIC DISORDERS

The physiological role of DC-SIGN: A tale of mice and men

(2013) Juan J. Garcia-Vallejo et al.   TRENDS IN IMMUNOLOGY

Microbes Bind Complement Inhibitor Factor H via a Common Site

(2013) T. Meri et al.   PLoS Pathogens

Multifarious roles of sialic acids in immunity

(2012) Ajit Varki et al.   Annals of the New York Academy of Sciences

STEC-HUS, atypical HUS and TTP are all diseases of complement activation

(2012) Marina Noris et al.   Nature Reviews Nephrology

CTRP family: linking immunity to metabolism

(2012) Andreas Schäffler et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

The salivary scavenger and agglutinin binds MBL and regulates the lectin pathway of complement in solution and on surfaces

(2012) Martin P. Reichhardt et al.   Frontiers in Immunology

The bacteria binding glycoprotein salivary agglutinin (SAG/gp340) activates complement via the lectin pathway

(2011) Jelani T.D. Leito et al.   MOLECULAR IMMUNOLOGY

Mutations in lectin complement pathway genes COLEC11 and MASP1 cause 3MC syndrome

(2011) Caroline Rooryck et al.   NATURE GENETICS

Structural basis for engagement by complement factor H of C3b on a self surface

(2011) Hugh P Morgan et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Dual interaction of factor H with C3d and glycosaminoglycans in host-nonhost discrimination by complement

(2011) T. Kajander et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Rational Design of a Meningococcal Antigen Inducing Broad Protective Immunity

(2011) M. Scarselli et al.   Science Translational Medicine

Review: Gp-340/DMBT1 in mucosal innate immunity

(2010) Jens Madsen et al.   Innate Immunity

Impaired Binding of the Age-related Macular Degeneration-associated Complement Factor H 402H Allotype to Bruch's Membrane in Human Retina

(2010) Simon J. Clark et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Identification of a mutation in complement factor H-related protein 5 in patients of Cypriot origin with glomerulonephritis

(2010) Daniel P Gale et al.   LANCET

Complement: a key system for immune surveillance and homeostasis

(2010) Daniel Ricklin et al.   NATURE IMMUNOLOGY

Molecular mechanisms of complement evasion: learning from staphylococci and meningococci

(2010) Davide Serruto et al.   NATURE REVIEWS MICROBIOLOGY

Atypical Hemolytic Uremic Syndrome Associated with Mutations in Complement Regulator Genes

(2010) Moglie Le Quintrec et al.   SEMINARS IN THROMBOSIS AND HEMOSTASIS

Anti-Factor H Autoantibody–Associated Hemolytic Uremic Syndrome: Review of Literature of the Autoimmune Form of HUS

(2010) Marie-Agnès Dragon-Durey et al.   SEMINARS IN THROMBOSIS AND HEMOSTASIS

iC3b-opsonized apoptotic cells mediate a distinct anti-inflammatory response and transcriptional NF-κB-dependent blockade

(2009) Gil Amarilyo et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Mutations of Factor H Impair Regulation of Surface-bound C3b by Three Mechanisms in Atypical Hemolytic Uremic Syndrome

(2009) Markus J. Lehtinen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Complement Factor H Binds at Two Independent Sites to C-reactive Protein in Acute Phase Concentrations

(2009) Azubuike I. Okemefuna et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

MBL2, FCN1, FCN2 and FCN3—The genes behind the initiation of the lectin pathway of complement

(2009) Peter Garred et al.   MOLECULAR IMMUNOLOGY

Antimalarial Responses in Anopheles gambiae: From a Complement-like Protein to a Complement-like Pathway

(2008) Stéphanie A. Blandin et al.   Cell Host & Microbe

Natural killer cell recognition of missing self

(2008) Klas Kärre   NATURE IMMUNOLOGY

Microbial complement inhibitors as vaccines

(2008) Seppo Meri et al.   VACCINE