Thrombosis in paroxysmal nocturnal hemoglobinuria

Under-recognized complications in patients with paroxysmal nocturnal haemoglobinuria: raised pulmonary pressure and reduced right ventricular function

(2012) Anita Hill et al.   BRITISH JOURNAL OF HAEMATOLOGY

Eculizumab therapy results in rapid and sustained decreases in markers of thrombin generation and inflammation in patients with PNH independent of its effects on hemolysis and microparticle formation

(2012) Ilene C. Weitz et al.   THROMBOSIS RESEARCH

Long-term treatment with eculizumab in paroxysmal nocturnal hemoglobinuria: sustained efficacy and improved survival

(2011) R. J. Kelly et al.   BLOOD

Management of Paroxysmal Nocturnal Haemoglobinuria: a personal view

(2011) Lucio Luzzatto et al.   BRITISH JOURNAL OF HAEMATOLOGY

Thrombolytic therapy is effective in paroxysmal nocturnal hemoglobinuria: a series of nine patients and a review of the literature

(2011) D. J. Araten et al.   HAEMATOLOGICA

Loss of expression of neutrophil proteinase-3: a factor contributing to thrombotic risk in paroxysmal nocturnal hemoglobinuria

(2011) A. M. Jankowska et al.   HAEMATOLOGICA

The critical roles of platelet activation and reduced NO bioavailability in fatal pulmonary arterial hypertension in a murine hemolysis model

(2010) W. Hu et al.   BLOOD

Effect of eculizumab on haemolysis-associated nitric oxide depletion, dyspnoea, and measures of pulmonary hypertension in patients with paroxysmal nocturnal haemoglobinuria

(2010) Anita Hill et al.   BRITISH JOURNAL OF HAEMATOLOGY

Eculizumab prevents intravascular hemolysis in patients with paroxysmal nocturnal hemoglobinuria and unmasks low-level extravascular hemolysis occurring through C3 opsonization

(2010) A. Hill et al.   HAEMATOLOGICA

Evaluation of hemostasis and endothelial function in patients with paroxysmal nocturnal hemoglobinuria receiving eculizumab

(2010) D. Helley et al.   HAEMATOLOGICA

Complement activation on platelets: Implications for vascular inflammation and thrombosis

(2010) Ellinor I. Peerschke et al.   MOLECULAR IMMUNOLOGY

Reciprocal coupling of coagulation and innate immunity via neutrophil serine proteases

(2010) Steffen Massberg et al.   NATURE MEDICINE

Successful discontinuation of anticoagulation following eculizumab administration in paroxysmal nocturnal hemoglobinuria

(2009) Ashkan Emadi et al.   AMERICAN JOURNAL OF HEMATOLOGY

Complement fraction 3 binding on erythrocytes as additional mechanism of disease in paroxysmal nocturnal hemoglobinuria patients treated by eculizumab

(2009) A. M. Risitano et al.   BLOOD

Coagulation and innate immune responses: can we view them separately?

(2009) M. Delvaeye et al.   BLOOD

Complement activation on platelets correlates with a decrease in circulating immature platelets in patients with immune thrombocytopenic purpura

(2009) Ellinor I. B. Peerschke et al.   BRITISH JOURNAL OF HAEMATOLOGY

Platelet Polyphosphates Are Proinflammatory and Procoagulant Mediators In Vivo

(2009) Felicitas Müller et al.   CELL

Abnormalities in the expression of CD55 and CD59 surface molecules on peripheral blood cells are not specific to paroxysmal nocturnal hemoglobinuria

(2009) Guillermo J. Ruiz-Delgado et al.   Hematology

Paroxysmal nocturnal hemoglobinuria in Budd-Chiari Syndrome: Findings from a cohort study

(2009) Jildou Hoekstra et al.   JOURNAL OF HEPATOLOGY

Paroxysmal nocturnal hemoglobinuria following alemtuzumab immunosuppressive therapy for myelodysplastic syndrome and complicated by recurrent life-threatening thrombosis despite anticoagulation: Successful intervention with eculizumab and fondaparinux

(2009) Kit L. Cheng et al.   LEUKEMIA RESEARCH

Successful liver transplantation for Budd-Chiari syndrome in a patient with paroxysmal nocturnal hemoglobinuria treated with the anti-complement antibody eculizumab

(2009) Andrew L. Singer et al.   LIVER TRANSPLANTATION

Serum complement activation on heterologous platelets is associated with arterial thrombosis in patients with systemic lupus erythematosus and antiphospholipid antibodies

(2009) EIB Peerschke et al.   LUPUS

Splenic infarction and subsequent splenic rupture in a patient with paroxysmal nocturnal hemoglobinuria and heparin-induced thrombocytopenia

(2009) Heather Magnan et al.   PEDIATRIC BLOOD & CANCER

Lysis and thrombosis: Manifestation of the same disease

(2008) Smyrna Abou Antoun et al.   AMERICAN JOURNAL OF HEMATOLOGY

Paroxysmal nocturnal hemoglobinuria: natural history of disease subcategories

(2008) R. P. de Latour et al.   BLOOD

Thrombosis in Paroxysmal Nocturnal Hemoglobinuria at a Glance: A Clinical Review

(2008) Panayiotis Ziakas et al.   Current Vascular Pharmacology

Oxidative status of red blood cells, neutrophils, and platelets in paroxysmal nocturnal hemoglobinuria

(2008) Johnny Amer et al.   EXPERIMENTAL HEMATOLOGY

Complement activation triggered by chondroitin sulfate released by thrombin receptor-activated platelets

(2008) O. A. HAMAD et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Expression of tissue factor pathway inhibitor by endothelial cells and platelets

(2008) Susan A. Maroney et al.   TRANSFUSION AND APHERESIS SCIENCE