Inhibition of ER stress and unfolding protein response pathways causes skeletal muscle wasting during cancer cachexia

Lewis lung carcinoma regulation of mechanical stretch-induced protein synthesis in cultured myotubes

(2016) Song Gao et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Aging related ER stress is not responsible for anabolic resistance in mouse skeletal muscle

(2015) Sreeda Chalil et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Elevated levels of TWEAK in skeletal muscle promote visceral obesity, insulin resistance, and metabolic dysfunction

(2015) Shuichi Sato et al.   FASEB JOURNAL

A Key Role for Leukemia Inhibitory Factor in C26 Cancer Cachexia

(2015) Danielle N. Seto et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Reduction of ER stress via a chemical chaperone prevents disease phenotypes in a mouse model of primary open angle glaucoma

(2015) Gulab S. Zode et al.   JOURNAL OF CLINICAL INVESTIGATION

Expanding roles for AMPK in skeletal muscle plasticity

(2015) Rémi Mounier et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Genome-wide identification of FoxO-dependent gene networks in skeletal muscle during C26 cancer cachexia

(2015) Sarah M Judge et al.   BMC CANCER

Acylated and unacylated ghrelin inhibit doxorubicin-induced apoptosis in skeletal muscle

(2014) A. P. Yu et al.   Acta Physiologica

4-Phenylbutyric Acid Increases GLUT4 Gene Expression through Suppression of HDAC5 but not Endoplasmic Reticulum Stress

(2014) Hailong Hu et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Increased skeletal muscle expression of the endoplasmic reticulum chaperone GRP78 in patients with myasthenia gravis

(2014) Kazuo Iwasa et al.   JOURNAL OF NEUROIMMUNOLOGY

C26 Cancer-Induced Muscle Wasting Is IKKβ-Dependent and NF-kappaB-Independent

(2014) Evangeline W. Cornwell et al.   PLoS One

Maintenance of muscle mass and load-induced growth in Muscle RING Finger 1 null mice with age

(2013) Darren T. Hwee et al.   AGING CELL

Autophagic Degradation Contributes to Muscle Wasting in Cancer Cachexia

(2013) Fabio Penna et al.   AMERICAN JOURNAL OF PATHOLOGY

Signaling pathways controlling skeletal muscle mass

(2013) Marc A. Egerman et al.   CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY

Mechanisms for fiber-type specificity of skeletal muscle atrophy

(2013) Yichen Wang et al.   CURRENT OPINION IN CLINICAL NUTRITION AND METABOLIC CARE

Oleate prevents saturated-fatty-acid-induced ER stress, inflammation and insulin resistance in skeletal muscle cells through an AMPK-dependent mechanism

(2013) L. Salvadó et al.   DIABETOLOGIA

Signaling mechanism of tumor cell-induced up-regulation of E3 ubiquitin ligase UBR2

(2013) Guohua Zhang et al.   FASEB JOURNAL

Regulatory circuitry of TWEAK-Fn14 system and PGC-1α in skeletal muscle atrophy program

(2013) Sajedah M. Hindi et al.   FASEB JOURNAL

Muscle wasting in cancer

(2013) N. Johns et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

BMP signaling controls muscle mass

(2013) Roberta Sartori et al.   NATURE GENETICS

Tribbles 3 mediates endoplasmic reticulum stress-induced insulin resistance in skeletal muscle

(2013) Ho-Jin Koh et al.   Nature Communications

Cancer Cachexia: Mediators, Signaling, and Metabolic Pathways

(2012) Kenneth C.H. Fearon et al.   Cell Metabolism

Measuring Protein Synthesis With SUnSET

(2012) Craig A. Goodman et al.   EXERCISE AND SPORT SCIENCES REVIEWS

Upregulation of proteasome activity in muscle RING finger 1-null mice following denervation

(2012) Aldrin V. Gomes et al.   FASEB JOURNAL

The E3 Ubiquitin Ligase TRAF6 Intercedes in Starvation-Induced Skeletal Muscle Atrophy through Multiple Mechanisms

(2012) P. K. Paul et al.   MOLECULAR AND CELLULAR BIOLOGY

The unfolded protein response: controlling cell fate decisions under ER stress and beyond

(2012) Claudio Hetz   NATURE REVIEWS MOLECULAR CELL BIOLOGY

New insights into ER stress-induced insulin resistance

(2012) Mélissa Flamment et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Endoplasmic Reticulum Stress in Skeletal Muscle Homeostasis and Disease

(2012) Sree Rayavarapu et al.   Current Rheumatology Reports

The Unfolded Protein Response Mediates Adaptation to Exercise in Skeletal Muscle through a PGC-1α/ATF6α Complex

(2011) Jun Wu et al.   Cell Metabolism

C/EBPβ mediates tumour-induced ubiquitin ligase atrogin1/MAFbx upregulation and muscle wasting

(2011) Guohua Zhang et al.   EMBO JOURNAL

Endoplasmic reticulum stress response in P104L mutant caveolin-3 transgenic mice

(2011) Atsushi Kuga et al.   HUMAN MOLECULAR GENETICS

Definition and classification of cancer cachexia: an international consensus

(2011) Kenneth Fearon et al.   LANCET ONCOLOGY

Endoplasmic reticulum stress, obesity and diabetes

(2011) Miriam Cnop et al.   TRENDS IN MOLECULAR MEDICINE

Autophagy in skeletal muscle

(2010) Marco Sandri   FEBS LETTERS

The TWEAK–Fn14 system is a critical regulator of denervation-induced skeletal muscle atrophy in mice

(2010) Ashwani Mittal et al.   JOURNAL OF CELL BIOLOGY

Targeted ablation of TRAF6 inhibits skeletal muscle wasting in mice

(2010) Pradyut K. Paul et al.   JOURNAL OF CELL BIOLOGY

The Transcription Factor ATF4 Promotes Skeletal Myofiber Atrophy during Fasting

(2010) Scott M. Ebert et al.   MOLECULAR ENDOCRINOLOGY

Role of systemic inflammatory response in predicting survival in patients with primary operable cancer

(2009) Campbell SD Roxburgh et al.   Future Oncology

Signaling in Muscle Atrophy and Hypertrophy

(2008) Marco Sandri   PHYSIOLOGY

Interleukin-6 and cachexia in ApcMin/+ mice

(2007) Kristen A. Baltgalvis et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY