Regulatory circuitry of TWEAK-Fn14 system and PGC-1α in skeletal muscle atrophy program

PGC1α Plays a Critical Role in TWEAK–Induced Cardiac Dysfunction

(2013) Jianru Shi et al.   PLoS One

TWEAK promotes exercise intolerance by decreasing skeletal muscle oxidative phosphorylation capacity

(2013) Shuichi Sato et al.   Skeletal Muscle

RETRACTED: The Ubiquitin Ligase Mul1 Induces Mitophagy in Skeletal Muscle in Response to Muscle-Wasting Stimuli

(2012) Sudarsanareddy Lokireddy et al.   Cell Metabolism

Cellular and molecular mechanisms of muscle atrophy

(2012) P. Bonaldo et al.   Disease Models & Mechanisms

The Peroxisome Proliferator-activated Receptor γ Coactivator 1α/β (PGC-1) Coactivators Repress the Transcriptional Activity of NF-κB in Skeletal Muscle Cells

(2012) Petra S. Eisele et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The E3 Ubiquitin Ligase TRAF6 Intercedes in Starvation-Induced Skeletal Muscle Atrophy through Multiple Mechanisms

(2012) P. K. Paul et al.   MOLECULAR AND CELLULAR BIOLOGY

Reciprocal Interaction between TRAF6 and Notch Signaling Regulates Adult Myofiber Regeneration upon Injury

(2012) S. M. Hindi et al.   MOLECULAR AND CELLULAR BIOLOGY

The TWEAK-Fn14 System: Breaking the Silence of Cytokine-Induced Skeletal Muscle Wasting

(2011) S. Bhatnagar et al.   CURRENT MOLECULAR MEDICINE

TWEAK causes myotube atrophy through coordinated activation of ubiquitin-proteasome system, autophagy, and caspases

(2011) Shephali Bhatnagar et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Identification of Genes that Elicit Disuse Muscle Atrophy via the Transcription Factors p50 and Bcl-3

(2011) Chia-Ling Wu et al.   PLoS One

Signaling pathways perturbing muscle mass

(2010) David J Glass   CURRENT OPINION IN CLINICAL NUTRITION AND METABOLIC CARE

Mitochondrial fission and remodelling contributes to muscle atrophy

(2010) Vanina Romanello et al.   EMBO JOURNAL

Peroxisome Proliferator-activated Receptor γ Coactivator 1α or 1β Overexpression Inhibits Muscle Protein Degradation, Induction of Ubiquitin Ligases, and Disuse Atrophy

(2010) Jeffrey J. Brault et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The TWEAK–Fn14 system is a critical regulator of denervation-induced skeletal muscle atrophy in mice

(2010) Ashwani Mittal et al.   JOURNAL OF CELL BIOLOGY

Targeted ablation of TRAF6 inhibits skeletal muscle wasting in mice

(2010) Pradyut K. Paul et al.   JOURNAL OF CELL BIOLOGY

During muscle atrophy, thick, but not thin, filament components are degraded by MuRF1-dependent ubiquitylation

(2009) Shenhav Cohen et al.   JOURNAL OF CELL BIOLOGY

Increased muscle PGC-1  expression protects from sarcopenia and metabolic disease during aging

(2009) T. Wenz et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

PGC-1 coactivators and skeletal muscle adaptations in health and disease

(2008) Zolt Arany   CURRENT OPINION IN GENETICS & DEVELOPMENT

Muscle-specific expression of PPARγ coactivator-1α improves exercise performance and increases peak oxygen uptake

(2008) Jennifer A. Calvo et al.   JOURNAL OF APPLIED PHYSIOLOGY

No end in site: TWEAK/Fn14 activation and autoimmunity associated- end-organ pathologies

(2008) Timothy S. Zheng et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Nuclear factor-kappa B signaling in skeletal muscle atrophy

(2008) Hong Li et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

The TWEAK–Fn14 cytokine–receptor axis: discovery, biology and therapeutic targeting

(2008) Jeffrey A. Winkles   NATURE REVIEWS DRUG DISCOVERY