Aneuploid senescent cells activate NF‐κB to promote their immune clearance by NK cells
Published 2021 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Aneuploid senescent cells activate NF‐κB to promote their immune clearance by NK cells
Authors
Keywords
-
Journal
EMBO REPORTS
Volume 22, Issue 8, Pages -
Publisher
EMBO
Online
2021-06-09
DOI
10.15252/embr.202052032
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Aneuploidy renders cancer cells vulnerable to mitotic checkpoint inhibition
- (2021) Yael Cohen-Sharir et al. NATURE
- Single-Chromosomal Gains Can Function as Metastasis Suppressors and Promoters in Colon Cancer
- (2020) Anand Vasudevan et al. DEVELOPMENTAL CELL
- NK cells for cancer immunotherapy
- (2020) Noriko Shimasaki et al. NATURE REVIEWS DRUG DISCOVERY
- Understanding Complexity of Cancer Genomes: Lessons from Errors
- (2020) Sara Martin et al. DEVELOPMENTAL CELL
- L1 drives IFN in senescent cells and promotes age-associated inflammation
- (2019) Marco De Cecco et al. NATURE
- The mTORC1-autophagy pathway is a target for senescent cell elimination
- (2019) Olena Kucheryavenko et al. BIOGERONTOLOGY
- Next-generation characterization of the Cancer Cell Line Encyclopedia
- (2019) Mahmoud Ghandi et al. NATURE
- Context is everything: aneuploidy in cancer
- (2019) Uri Ben-David et al. NATURE REVIEWS GENETICS
- Cellular Senescence: Defining a Path Forward
- (2019) Vassilis Gorgoulis et al. CELL
- Genomic and Functional Approaches to Understanding Cancer Aneuploidy
- (2018) Alison M. Taylor et al. CANCER CELL
- Chromosomal instability drives metastasis through a cytosolic DNA response
- (2018) Samuel F. Bakhoum et al. NATURE
- Small-molecule MDM2 antagonists attenuate the senescence-associated secretory phenotype
- (2018) Christopher D. Wiley et al. Scientific Reports
- Chromosomal Instability Induces Cellular Invasion in Epithelial Tissues
- (2018) Najate Benhra et al. DEVELOPMENTAL CELL
- Non-canonical Activation of the DNA Sensing Adaptor STING by ATM and IFI16 Mediates NF-κB Signaling after Nuclear DNA Damage
- (2018) Gillian Dunphy et al. MOLECULAR CELL
- Nuclear envelope assembly defects link mitotic errors to chromothripsis
- (2018) Shiwei Liu et al. NATURE
- cGAS surveillance of micronuclei links genome instability to innate immunity
- (2017) Karen J. Mackenzie et al. NATURE
- Mitotic progression following DNA damage enables pattern recognition within micronuclei
- (2017) Shane M. Harding et al. NATURE
- Cytoplasmic chromatin triggers inflammation in senescence and cancer
- (2017) Zhixun Dou et al. NATURE
- Innate immune sensing of cytosolic chromatin fragments through cGAS promotes senescence
- (2017) Selene Glück et al. NATURE CELL BIOLOGY
- Tumor aneuploidy correlates with markers of immune evasion and with reduced response to immunotherapy
- (2017) Teresa Davoli et al. SCIENCE
- NKG2D ligands mediate immunosurveillance of senescent cells
- (2016) Adi Sagiv et al. Aging-US
- Genomic Instability in Human Pluripotent Stem Cells Arises from Replicative Stress and Chromosome Condensation Defects
- (2016) Noa Lamm et al. Cell Stem Cell
- Gene Dosage Imbalance Contributes to Chromosomal Instability-Induced Tumorigenesis
- (2016) Marta Clemente-Ruiz et al. DEVELOPMENTAL CELL
- Aneuploidy impairs hematopoietic stem cell fitness and is selected against in regenerating tissues in vivo
- (2016) Sarah J. Pfau et al. GENES & DEVELOPMENT
- The presence of extra chromosomes leads to genomic instability
- (2016) Verena Passerini et al. Nature Communications
- Aneuploidy-induced cellular stresses limit autophagic degradation
- (2015) Stefano Santaguida et al. GENES & DEVELOPMENT
- Short- and long-term effects of chromosome mis-segregation and aneuploidy
- (2015) Stefano Santaguida et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- limma powers differential expression analyses for RNA-sequencing and microarray studies
- (2015) Matthew E. Ritchie et al. NUCLEIC ACIDS RESEARCH
- Aneuploidy generates proteotoxic stress and DNA damage concurrently with p53-mediated post-mitotic apoptosis in SAC-impaired cells
- (2015) Akihiro Ohashi et al. Nature Communications
- Dual mTORC1/C2 inhibitors: gerosuppressors with potential anti-aging effect
- (2015) Pedro Sousa-Victor et al. Oncotarget
- The Molecular Signatures Database Hallmark Gene Set Collection
- (2015) Arthur Liberzon et al. Cell Systems
- Unique features of the transcriptional response to model aneuploidy in human cells
- (2014) Milena Dürrbaum et al. BMC GENOMICS
- Role of Toll-Like Receptor 13 in Innate Immune Recognition of Group B Streptococci
- (2014) Giacomo Signorino et al. INFECTION AND IMMUNITY
- Reactive Oxygen Species– and DNA Damage Response–Dependent NK Cell Activating Ligand Upregulation Occurs at Transcriptional Levels and Requires the Transcriptional Factor E2F1
- (2014) Alessandra Soriani et al. JOURNAL OF IMMUNOLOGY
- p53-dependent chemokine production by senescent tumor cells supports NKG2D-dependent tumor elimination by natural killer cells
- (2013) Alexandre Iannello et al. JOURNAL OF EXPERIMENTAL MEDICINE
- STAR: ultrafast universal RNA-seq aligner
- (2012) Alexander Dobin et al. BIOINFORMATICS
- Chromosomal instability and aneuploidy in cancer: from yeast to man
- (2012) Sarah J Pfau et al. EMBO REPORTS
- NF- B, the first quarter-century: remarkable progress and outstanding questions
- (2012) M. S. Hayden et al. GENES & DEVELOPMENT
- Global analysis of genome, transcriptome and proteome reveals the response to aneuploidy in human cells
- (2012) Silvia Stingele et al. Molecular Systems Biology
- DNA breaks and chromosome pulverization from errors in mitosis
- (2012) Karen Crasta et al. NATURE
- The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity
- (2012) Jordi Barretina et al. NATURE
- Causes and consequences of aneuploidy in cancer
- (2012) David J. Gordon et al. NATURE REVIEWS GENETICS
- Transcriptional consequences of aneuploidy
- (2012) J. M. Sheltzer et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- RSEM: accurate transcript quantification from RNA-Seq data with or without a reference genome
- (2011) Bo Li et al. BMC BIOINFORMATICS
- Chromosome Segregation Errors as a Cause of DNA Damage and Structural Chromosome Aberrations
- (2011) A. Janssen et al. SCIENCE
- Identification of Aneuploidy-Tolerating Mutations
- (2010) Eduardo M. Torres et al. CELL
- DNA Topoisomerases and Their Poisoning by Anticancer and Antibacterial Drugs
- (2010) Yves Pommier et al. CHEMISTRY & BIOLOGY
- Dissecting the role of MPS1 in chromosome biorientation and the spindle checkpoint through the small molecule inhibitor reversine
- (2010) Stefano Santaguida et al. JOURNAL OF CELL BIOLOGY
- The ATM-p53 pathway suppresses aneuploidy-induced tumorigenesis
- (2010) M. Li et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The Sequence Alignment/Map format and SAMtools
- (2009) H. Li et al. BIOINFORMATICS
- ATM-ATR-dependent up-regulation of DNAM-1 and NKG2D ligands on multiple myeloma cells by therapeutic agents results in enhanced NK-cell susceptibility and is associated with a senescent phenotype
- (2008) A. Soriani et al. BLOOD
- Induction of senescence with doxorubicin leads to increased genomic instability of HCT116 cells
- (2008) Malgorzata A. Sliwinska et al. MECHANISMS OF AGEING AND DEVELOPMENT
- Replacement of normal with mutant alleles in the genome of normal human cells unveils mutation-specific drug responses
- (2008) F. Di Nicolantonio et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Aneuploidy Affects Proliferation and Spontaneous Immortalization in Mammalian Cells
- (2008) B. R. Williams et al. SCIENCE
Add your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload NowBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started