Mitogen‐activated protein kinase activity drives cell trajectories in colorectal cancer
Published 2021 View Full Article
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Title
Mitogen‐activated protein kinase activity drives cell trajectories in colorectal cancer
Authors
Keywords
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Journal
EMBO Molecular Medicine
Volume -, Issue -, Pages -
Publisher
EMBO
Online
2021-08-19
DOI
10.15252/emmm.202114123
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Note: Only part of the references are listed.- A pre-existing population of ZEB2+ quiescent cells with stemness and mesenchymal features dictate chemoresistance in colorectal cancer
- (2020) Federica Francescangeli et al. JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
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- (2020) Kylie R. James et al. NATURE IMMUNOLOGY
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- (2020) Lei Zhang et al. CELL
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- (2020) Hae-Ock Lee et al. NATURE GENETICS
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- (2020) Junbin Qian et al. CELL RESEARCH
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- (2020) Volker Bergen et al. NATURE BIOTECHNOLOGY
- Colorectal cancer residual disease at maximal response to EGFR blockade displays a druggable Paneth cell–like phenotype
- (2020) Barbara Lupo et al. Science Translational Medicine
- LifeTime and improving European healthcare through cell-based interceptive medicine
- (2020) Nikolaus Rajewsky et al. NATURE
- SFPQ Depletion Is Synthetically Lethal with BRAFV600E in Colorectal Cancer Cells
- (2020) Kathleen Klotz-Noack et al. Cell Reports
- Spatiotemporal regulation of clonogenicity in colorectal cancer xenografts
- (2019) Maartje van der Heijden et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Colonic epithelial cell diversity in health and inflammatory bowel disease
- (2019) Kaushal Parikh et al. NATURE
- Self-organization and symmetry breaking in intestinal organoid development
- (2019) Denise Serra et al. NATURE
- Genomic and Transcriptomic Determinants of Therapy Resistance and Immune Landscape Evolution during Anti-EGFR Treatment in Colorectal Cancer
- (2019) Andrew Woolston et al. CANCER CELL
- Comprehensive Integration of Single-Cell Data
- (2019) Tim Stuart et al. CELL
- Intra- and Inter-cellular Rewiring of the Human Colon during Ulcerative Colitis
- (2019) Christopher S. Smillie et al. CELL
- Lineage tracing and targeting of IL17RB+tuft cell-like human colorectal cancer stem cells
- (2019) Norihiro Goto et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Cell type-dependent differential activation of ERK by oncogenic KRAS in colon cancer and intestinal epithelium
- (2019) Raphael Brandt et al. Nature Communications
- MEK inhibitors activate Wnt signalling and induce stem cell plasticity in colorectal cancer
- (2019) Tianzuo Zhan et al. Nature Communications
- The Molecular Hallmarks of the Serrated Pathway in Colorectal Cancer
- (2019) Fatima De Palma et al. Cancers
- Encorafenib, Binimetinib, and Cetuximab in BRAF V600E–Mutated Colorectal Cancer
- (2019) Scott Kopetz et al. NEW ENGLAND JOURNAL OF MEDICINE
- Dissecting newly transcribed and old RNA using GRAND-SLAM
- (2018) Christopher Jürges et al. BIOINFORMATICS
- Perturbation-response genes reveal signaling footprints in cancer gene expression
- (2018) Michael Schubert et al. Nature Communications
- Combined BRAF, EGFR, and MEK Inhibition in Patients with BRAF V600E -Mutant Colorectal Cancer
- (2018) Ryan B. Corcoran et al. Cancer Discovery
- Compensation of Signal Spillover in Suspension and Imaging Mass Cytometry
- (2018) Stéphane Chevrier et al. Cell Systems
- Visualization and targeting of LGR5+ human colon cancer stem cells
- (2017) Mariko Shimokawa et al. NATURE
- Thiol-linked alkylation of RNA to assess expression dynamics
- (2017) Veronika A Herzog et al. NATURE METHODS
- Molecular dissection of colorectal cancer in pre-clinical models identifies biomarkers predicting sensitivity to EGFR inhibitors
- (2017) Moritz Schütte et al. Nature Communications
- DNA copy number changes define spatial patterns of heterogeneity in colorectal cancer
- (2017) Soulafa Mamlouk et al. Nature Communications
- Multicolor lineage tracing reveals clonal architecture and dynamics in colon cancer
- (2017) Sebastian Lamprecht et al. Nature Communications
- Degree of Tissue Differentiation Dictates Susceptibility to BRAF-Driven Colorectal Cancer
- (2017) Kevin Tong et al. Cell Reports
- YAP/TAZ at the Roots of Cancer
- (2016) Francesca Zanconato et al. CANCER CELL
- Inflammatory networks underlying colorectal cancer
- (2016) Audrey Lasry et al. NATURE IMMUNOLOGY
- Single-cell RNA-seq reveals changes in cell cycle and differentiation programs upon aging of hematopoietic stem cells
- (2015) Monika S. Kowalczyk et al. GENOME RESEARCH
- The consensus molecular subtypes of colorectal cancer
- (2015) Justin Guinney et al. NATURE MEDICINE
- The Molecular Signatures Database Hallmark Gene Set Collection
- (2015) Arthur Liberzon et al. Cell Systems
- Evolution of the Cancer Stem Cell Model
- (2014) Antonija Kreso et al. Cell Stem Cell
- Transgenic expression of oncogenic BRAF induces loss of stem cells in the mouse intestine, which is antagonized by β-catenin activity
- (2014) P Riemer et al. ONCOGENE
- Resistance to Anti-EGFR Therapy in Colorectal Cancer: From Heterogeneity to Convergent Evolution
- (2014) S. Misale et al. Cancer Discovery
- Intestinal label-retaining cells are secretory precursors expressing Lgr5
- (2013) Simon J. A. Buczacki et al. NATURE
- Mutant BRAF Induces DNA Strand Breaks, Activates DNA Damage Response Pathway, and Up-Regulates Glucose Transporter-1 in Nontransformed Epithelial Cells
- (2012) Jim Jinn-Chyuan Sheu et al. AMERICAN JOURNAL OF PATHOLOGY
- Snakemake--a scalable bioinformatics workflow engine
- (2012) J. Koster et al. BIOINFORMATICS
- Intestinal Tumorigenesis Initiated by Dedifferentiation and Acquisition of Stem-Cell-like Properties
- (2012) Sarah Schwitalla et al. CELL
- The Lgr5 intestinal stem cell signature: robust expression of proposed quiescent ‘+4’ cell markers
- (2012) Javier Muñoz et al. EMBO JOURNAL
- Molecular Genetics of Colorectal Cancer
- (2011) Eric R. Fearon Annual Review of Pathology-Mechanisms of Disease
- Hallmarks of Cancer: The Next Generation
- (2011) Douglas Hanahan et al. CELL
- The Intestinal Stem Cell Signature Identifies Colorectal Cancer Stem Cells and Predicts Disease Relapse
- (2011) Anna Merlos-Suárez et al. Cell Stem Cell
- Long-term Expansion of Epithelial Organoids From Human Colon, Adenoma, Adenocarcinoma, and Barrett's Epithelium
- (2011) Toshiro Sato et al. GASTROENTEROLOGY
- Strong negative feedback from Erk to Raf confers robustness to MAPK signalling
- (2011) R. Fritsche-Guenther et al. Molecular Systems Biology
- RAF inhibitors prime wild-type RAF to activate the MAPK pathway and enhance growth
- (2010) Georgia Hatzivassiliou et al. NATURE
- Wnt activity defines colon cancer stem cells and is regulated by the microenvironment
- (2010) Louis Vermeulen et al. NATURE CELL BIOLOGY
- Cetuximab and Chemotherapy as Initial Treatment for Metastatic Colorectal Cancer
- (2009) Eric Van Cutsem et al. NEW ENGLAND JOURNAL OF MEDICINE
- SeqAn An efficient, generic C++ library for sequence analysis
- (2008) Andreas Döring et al. BMC BIOINFORMATICS
- Wild-TypeKRASIs Required for Panitumumab Efficacy in Patients With Metastatic Colorectal Cancer
- (2008) Rafael G. Amado et al. JOURNAL OF CLINICAL ONCOLOGY
- K-rasMutations and Benefit from Cetuximab in Advanced Colorectal Cancer
- (2008) Christos S. Karapetis et al. NEW ENGLAND JOURNAL OF MEDICINE
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