Molecular dissection of colorectal cancer in pre-clinical models identifies biomarkers predicting sensitivity to EGFR inhibitors
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Title
Molecular dissection of colorectal cancer in pre-clinical models identifies biomarkers predicting sensitivity to EGFR inhibitors
Authors
Keywords
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Journal
Nature Communications
Volume 8, Issue -, Pages 14262
Publisher
Springer Nature
Online
2017-02-10
DOI
10.1038/ncomms14262
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Note: Only part of the references are listed.- A Biobank of Breast Cancer Explants with Preserved Intra-tumor Heterogeneity to Screen Anticancer Compounds
- (2016) Alejandra Bruna et al. CELL
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- (2016) Tatsuya Yoshida et al. JOURNAL OF CLINICAL ONCOLOGY
- Nuclear AURKA acquires kinase-independent transactivating function to enhance breast cancer stem cell phenotype
- (2016) Feimeng Zheng et al. Nature Communications
- Non-CG DNA methylation is a biomarker for assessing endodermal differentiation capacity in pluripotent stem cells
- (2016) Lee M. Butcher et al. Nature Communications
- The AURKA/TPX2 axis drives colon tumorigenesis cooperatively with MYC
- (2015) Y. Takahashi et al. ANNALS OF ONCOLOGY
- Combination of microsatellite instability and BRAF mutation status for subtyping colorectal cancer
- (2015) T T Seppälä et al. BRITISH JOURNAL OF CANCER
- Evaluating Patient-Derived Colorectal Cancer Xenografts as Preclinical Models by Comparison with Patient Clinical Data
- (2015) M. Nunes et al. CANCER RESEARCH
- Molecular and Genetic Properties of Tumors Associated with Local Immune Cytolytic Activity
- (2015) Michael S. Rooney et al. CELL
- Prospective Derivation of a Living Organoid Biobank of Colorectal Cancer Patients
- (2015) Marc van de Wetering et al. CELL
- Ascl2 Acts as an R-spondin/Wnt-Responsive Switch to Control Stemness in Intestinal Crypts
- (2015) Jurian Schuijers et al. Cell Stem Cell
- Regulation of Endothelial Cell Proliferation and Vascular Assembly through Distinct mTORC2 Signaling Pathways
- (2015) Shan Wang et al. MOLECULAR AND CELLULAR BIOLOGY
- The genomic landscape of response to EGFR blockade in colorectal cancer
- (2015) Andrea Bertotti et al. NATURE
- Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity
- (2015) Matthew T Chang et al. NATURE BIOTECHNOLOGY
- Stromal gene expression defines poor-prognosis subtypes in colorectal cancer
- (2015) Alexandre Calon et al. NATURE GENETICS
- Stromal contribution to the colorectal cancer transcriptome
- (2015) Claudio Isella et al. NATURE GENETICS
- A Big Bang model of human colorectal tumor growth
- (2015) Andrea Sottoriva et al. NATURE GENETICS
- The consensus molecular subtypes of colorectal cancer
- (2015) Justin Guinney et al. NATURE MEDICINE
- High-throughput screening using patient-derived tumor xenografts to predict clinical trial drug response
- (2015) Hui Gao et al. NATURE MEDICINE
- IGF2 is an actionable target that identifies a distinct subpopulation of colorectal cancer patients with marginal response to anti-EGFR therapies
- (2015) Eugenia R. Zanella et al. Science Translational Medicine
- The molecular landscape of colorectal cancer cell lines unveils clinically actionable kinase targets
- (2015) Enzo Medico et al. Nature Communications
- Characterization of the immunophenotypes and antigenomes of colorectal cancers reveals distinct tumor escape mechanisms and novel targets for immunotherapy
- (2015) Mihaela Angelova et al. GENOME BIOLOGY
- Minfi: a flexible and comprehensive Bioconductor package for the analysis of Infinium DNA methylation microarrays
- (2014) Martin J. Aryee et al. BIOINFORMATICS
- Aberrant epithelial GREM1 expression initiates colonic tumorigenesis from cells outside the stem cell niche
- (2014) Hayley Davis et al. NATURE MEDICINE
- SciClone: Inferring Clonal Architecture and Tracking the Spatial and Temporal Patterns of Tumor Evolution
- (2014) Christopher A. Miller et al. PLoS Computational Biology
- GSVA: gene set variation analysis for microarray and RNA-Seq data
- (2013) Sonja Hänzelmann et al. BMC BIOINFORMATICS
- Epiregulin gene expression as a biomarker of benefit from cetuximab in the treatment of advanced colorectal cancer
- (2013) D J Jonker et al. BRITISH JOURNAL OF CANCER
- BRAF Fusions Define a Distinct Molecular Subset of Melanomas with Potential Sensitivity to MEK Inhibition
- (2013) K. E. Hutchinson et al. CLINICAL CANCER RESEARCH
- Spatiotemporal Dynamics of Intratumoral Immune Cells Reveal the Immune Landscape in Human Cancer
- (2013) Gabriela Bindea et al. IMMUNITY
- Metrics other than potency reveal systematic variation in responses to cancer drugs
- (2013) Mohammad Fallahi-Sichani et al. Nature Chemical Biology
- Recurrent somatic alterations of FGFR1 and NTRK2 in pilocytic astrocytoma
- (2013) David T W Jones et al. NATURE GENETICS
- Poor-prognosis colon cancer is defined by a molecularly distinct subtype and develops from serrated precursor lesions
- (2013) Felipe De Sousa E Melo et al. NATURE MEDICINE
- A colorectal cancer classification system that associates cellular phenotype and responses to therapy
- (2013) Anguraj Sadanandam et al. NATURE MEDICINE
- Panitumumab–FOLFOX4 Treatment and RAS Mutations in Colorectal Cancer
- (2013) Jean-Yves Douillard et al. NEW ENGLAND JOURNAL OF MEDICINE
- Gene Expression Classification of Colon Cancer into Molecular Subtypes: Characterization, Validation, and Prognostic Value
- (2013) Laetitia Marisa et al. PLOS MEDICINE
- Subtypes of primary colorectal tumors correlate with response to targeted treatment in colorectal cell lines
- (2012) Andreas Schlicker et al. BMC Medical Genomics
- Characterization of a Large Panel of Patient-Derived Tumor Xenografts Representing the Clinical Heterogeneity of Human Colorectal Cancer
- (2012) S. Julien et al. CLINICAL CANCER RESEARCH
- Addition of cetuximab to chemotherapy as first-line treatment for KRAS wild-type metastatic colorectal cancer: Pooled analysis of the CRYSTAL and OPUS randomised clinical trials
- (2012) Carsten Bokemeyer et al. EUROPEAN JOURNAL OF CANCER
- Regorafenib monotherapy for previously treated metastatic colorectal cancer (CORRECT): an international, multicentre, randomised, placebo-controlled, phase 3 trial
- (2012) Axel Grothey et al. LANCET
- Recurrent R-spondin fusions in colon cancer
- (2012) Somasekar Seshagiri et al. NATURE
- The ConsensusPathDB interaction database: 2013 update
- (2012) Atanas Kamburov et al. NUCLEIC ACIDS RESEARCH
- SCD1 Inhibition Causes Cancer Cell Death by Depleting Mono-Unsaturated Fatty Acids
- (2012) Paul Mason et al. PLoS One
- The Mammalian DM Domain Transcription Factor Dmrta2 Is Required for Early Embryonic Development of the Cerebral Cortex
- (2012) Daijiro Konno et al. PLoS One
- Direct and immune mediated antibody targeting of ERBB receptors in a colorectal cancer cell-line panel
- (2012) S. Q. Ashraf et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Long-term Expansion of Epithelial Organoids From Human Colon, Adenoma, Adenocarcinoma, and Barrett's Epithelium
- (2011) Toshiro Sato et al. GASTROENTEROLOGY
- Cetuximab Plus Irinotecan, Fluorouracil, and Leucovorin As First-Line Treatment for Metastatic Colorectal Cancer: Updated Analysis of Overall Survival According to Tumor KRAS and BRAF Mutation Status
- (2011) Eric Van Cutsem et al. JOURNAL OF CLINICAL ONCOLOGY
- Copy number variation detection in whole-genome sequencing data using the Bayesian information criterion
- (2011) R. Xi et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Activation of ERBB2 Signaling Causes Resistance to the EGFR-Directed Therapeutic Antibody Cetuximab
- (2011) K. Yonesaka et al. Science Translational Medicine
- A flexible R package for nonnegative matrix factorization
- (2010) Renaud Gaujoux et al. BMC BIOINFORMATICS
- Dindel: Accurate indel calls from short-read data
- (2010) C. A. Albers et al. GENOME RESEARCH
- 5-FU Metabolism in Cancer and Orally-Administrable 5-FU Drugs
- (2010) Koh Miura et al. Cancers
- Exon Array Profiling Detects EML4-ALK Fusion in Breast, Colorectal, and Non-Small Cell Lung Cancers
- (2009) E. Lin et al. MOLECULAR CANCER RESEARCH
- Transcriptome analysis by strand-specific sequencing of complementary DNA
- (2009) Dmitri Parkhomchuk et al. NUCLEIC ACIDS RESEARCH
- An Epigenetic Signature in Peripheral Blood Predicts Active Ovarian Cancer
- (2009) Andrew E. Teschendorff et al. PLoS One
- The Adenocarcinoma-Associated Antigen, AGR2, Promotes Tumor Growth, Cell Migration, and Cellular Transformation
- (2008) Z. Wang et al. CANCER RESEARCH
- New response evaluation criteria in solid tumours: Revised RECIST guideline (version 1.1)
- (2008) E.A. Eisenhauer et al. EUROPEAN JOURNAL OF CANCER
- Wild-TypeBRAFIs Required for Response to Panitumumab or Cetuximab in Metastatic Colorectal Cancer
- (2008) Federica Di Nicolantonio et al. JOURNAL OF CLINICAL ONCOLOGY
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