Transgenic expression of oncogenic BRAF induces loss of stem cells in the mouse intestine, which is antagonized by β-catenin activity
Published 2014 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Transgenic expression of oncogenic BRAF induces loss of stem cells in the mouse intestine, which is antagonized by β-catenin activity
Authors
Keywords
-
Journal
ONCOGENE
Volume 34, Issue 24, Pages 3164-3175
Publisher
Springer Nature
Online
2014-08-11
DOI
10.1038/onc.2014.247
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Role of Oncogenic K-Ras in Cancer Stem Cell Activation by Aberrant Wnt/β-Catenin Signaling
- (2014) Byoung-San Moon et al. JNCI-Journal of the National Cancer Institute
- A Genetic Progression Model of BrafV600E-Induced Intestinal Tumorigenesis Reveals Targets for Therapeutic Intervention
- (2013) Roland Rad et al. CANCER CELL
- MAPKs and Signal Transduction in the Control of Gastrointestinal Epithelial Cell Proliferation and Differentiation
- (2013) Luciana Osaki et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Gene expression profiling of serrated polyps identifies annexin A10 as a marker of a sessile serrated adenoma/polyp
- (2013) David Hernandez Gonzalo et al. JOURNAL OF PATHOLOGY
- A colorectal cancer classification system that associates cellular phenotype and responses to therapy
- (2013) Anguraj Sadanandam et al. NATURE MEDICINE
- Adult intestinal stem cells: critical drivers of epithelial homeostasis and regeneration
- (2013) Nick Barker NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Defining Stem Cell Dynamics in Models of Intestinal Tumor Initiation
- (2013) L. Vermeulen et al. SCIENCE
- A Novel Pit Pattern Identifies the Precursor of Colorectal Cancer Derived From Sessile Serrated Adenoma
- (2012) Tomoaki Kimura et al. AMERICAN JOURNAL OF GASTROENTEROLOGY
- Role of TAZ as Mediator of Wnt Signaling
- (2012) Luca Azzolin et al. CELL
- Intestinal Tumorigenesis Initiated by Dedifferentiation and Acquisition of Stem-Cell-like Properties
- (2012) Sarah Schwitalla et al. CELL
- The Lgr5 intestinal stem cell signature: robust expression of proposed quiescent ‘+4’ cell markers
- (2012) Javier Muñoz et al. EMBO JOURNAL
- Redundant Sources of Wnt Regulate Intestinal Stem Cells and Promote Formation of Paneth Cells
- (2012) Henner F. Farin et al. GASTROENTEROLOGY
- The serrated pathway to colorectal carcinoma: current concepts and challenges
- (2012) Mark Bettington et al. HISTOPATHOLOGY
- Wnt and BMP signals control intestinal adenoma cell fates
- (2012) Alexandra L. Farrall et al. INTERNATIONAL JOURNAL OF CANCER
- A Critical Role for the Wnt Effector Tcf4 in Adult Intestinal Homeostatic Self-Renewal
- (2012) J. H. van Es et al. MOLECULAR AND CELLULAR BIOLOGY
- The complex world of WNT receptor signalling
- (2012) Christof Niehrs NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Wnt/ -Catenin and MAPK Signaling: Allies and Enemies in Different Battlefields
- (2012) D. Guardavaccaro et al. Science Signaling
- Wnt/ -Catenin Signaling and AXIN1 Regulate Apoptosis Triggered by Inhibition of the Mutant Kinase BRAFV600E in Human Melanoma
- (2012) T. L. Biechele et al. Science Signaling
- Ras Stabilization Through Aberrant Activation of Wnt/ -Catenin Signaling Promotes Intestinal Tumorigenesis
- (2012) W.-J. Jeong et al. Science Signaling
- Molecular Genetics of Colorectal Cancer
- (2011) Eric R. Fearon Annual Review of Pathology-Mechanisms of Disease
- A novel MCF-10A line allowing conditional oncogene expression in 3D culture
- (2011) Ricarda Herr et al. Cell Communication and Signaling
- The Intestinal Stem Cell Signature Identifies Colorectal Cancer Stem Cells and Predicts Disease Relapse
- (2011) Anna Merlos-Suárez et al. Cell Stem Cell
- Long-term Expansion of Epithelial Organoids From Human Colon, Adenoma, Adenocarcinoma, and Barrett's Epithelium
- (2011) Toshiro Sato et al. GASTROENTEROLOGY
- Strong negative feedback from Erk to Raf confers robustness to MAPK signalling
- (2011) R. Fritsche-Guenther et al. Molecular Systems Biology
- Epigenetics and colorectal cancer
- (2011) Victoria Valinluck Lao et al. Nature Reviews Gastroenterology & Hepatology
- BRAF Mutations in Advanced Cancers: Clinical Characteristics and Outcomes
- (2011) Hazem El-Osta et al. PLoS One
- Amplification of the Driving Oncogene, KRAS or BRAF, Underpins Acquired Resistance to MEK1/2 Inhibitors in Colorectal Cancer Cells
- (2011) A. S. Little et al. Science Signaling
- Ink4a/Arf and Oncogene-Induced Senescence Prevent Tumor Progression during Alternative Colorectal Tumorigenesis
- (2010) Moritz Bennecke et al. CANCER CELL
- V600EBraf induces gastrointestinal crypt senescence and promotes tumour progression through enhanced CpG methylation ofp16INK4a
- (2010) Linda A. S. Carragher et al. EMBO Molecular Medicine
- Update on the serrated pathway to colorectal carcinoma
- (2010) Dale C. Snover HUMAN PATHOLOGY
- An inducible RNA interference system for the functional dissection of mouse embryogenesis
- (2010) Joana A. Vidigal et al. NUCLEIC ACIDS RESEARCH
- BRAF Gene Amplification Can Promote Acquired Resistance to MEK Inhibitors in Cancer Cells Harboring the BRAF V600E Mutation
- (2010) R. B. Corcoran et al. Science Signaling
- Identification of Y-Box Binding Protein 1 As a Core Regulator of MEK/ERK Pathway-Dependent Gene Signatures in Colorectal Cancer Cells
- (2010) Karsten Jürchott et al. PLoS Genetics
- Beta-catenin Nuclear Labeling is a Common Feature of Sessile Serrated Adenomas and Correlates With Early Neoplastic Progression After BRAF Activation
- (2009) Shinichi Yachida et al. AMERICAN JOURNAL OF SURGICAL PATHOLOGY
- Oncogenic Braf Induces Melanocyte Senescence and Melanoma in Mice
- (2009) Nathalie Dhomen et al. CANCER CELL
- A Two-Step Model for Colon Adenoma Initiation and Progression Caused by APC Loss
- (2009) Reid A. Phelps et al. CELL
- Frequent β-Catenin Nuclear Labeling in Sessile Serrated Polyps of the Colorectum With Neoplastic Potential
- (2008) Julie M. Wu et al. AMERICAN JOURNAL OF CLINICAL PATHOLOGY
- The Identification of 2-(1H-Indazol-4-yl)-6-(4-methanesulfonyl-piperazin-1-ylmethyl)-4-morpholin-4-yl-thieno[3,2-d]pyrimidine (GDC-0941) as a Potent, Selective, Orally Bioavailable Inhibitor of Class I PI3 Kinase for the Treatment of Cancer†
- (2008) Adrian J. Folkes et al. JOURNAL OF MEDICINAL CHEMISTRY
- The ground state of embryonic stem cell self-renewal
- (2008) Qi-Long Ying et al. NATURE
- Discovery of a selective inhibitor of oncogenic B-Raf kinase with potent antimelanoma activity
- (2008) J. Tsai et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExplorePublish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn More