Targeting FEN1 Suppresses the Proliferation of Chronic Myeloid Leukemia Cells Through Regulating Alternative End-Joining Pathways

Genetic Screens Reveal FEN1 and APEX2 as BRCA2 Synthetic Lethal Targets

(2019) Kristen E. Mengwasser et al.   MOLECULAR CELL

Discovery of Myricetin as a Potent Inhibitor of Human Flap Endonuclease 1, Which Potentially Can Be Used as Sensitizing Agent against HT-29 Human Colon Cancer Cells

(2019) Long Ma et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Non-homologous DNA end joining and alternative pathways to double-strand break repair

(2017) Howard H. Y. Chang et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Identification and characterization of intracellular proteins that bind oligonucleotides with phosphorothioate linkages

(2015) Xue-hai Liang et al.   NUCLEIC ACIDS RESEARCH

Nonhomologous end joining: A good solution for bad ends

(2014) Crystal A. Waters et al.   DNA REPAIR

Flap endonuclease 1 is a promising candidate biomarker in gastric cancer and is involved in cell proliferation and apoptosis

(2014) KEJIA WANG et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

Flap Endonuclease 1

(2013) Lata Balakrishnan et al.   Annual Review of Biochemistry

Homologous recombination and its regulation

(2012) L. Krejci et al.   NUCLEIC ACIDS RESEARCH

Targeting abnormal DNA double-strand break repair in tyrosine kinase inhibitor-resistant chronic myeloid leukemias

(2012) L A Tobin et al.   ONCOGENE

Genomic Instability in Chronic Myeloid Leukemia: Targets for Therapy?

(2012) N. Muvarak et al.   Current Hematologic Malignancy Reports

Mechanisms that Promote and Suppress Chromosomal Translocations in Lymphocytes

(2011) Monica Gostissa et al.   Annual Review of Immunology

Do reactive oxygen species play a role in myeloid leukemias?

(2011) P. S. Hole et al.   BLOOD

Hallmarks of Cancer: The Next Generation

(2011) Douglas Hanahan et al.   CELL

Targeting Abnormal DNA Repair in Therapy-Resistant Breast Cancers

(2011) L. A. Tobin et al.   MOLECULAR CANCER RESEARCH

Ku counteracts mobilization of PARP1 and MRN in chromatin damaged with DNA double-strand breaks

(2011) Qiao Cheng et al.   NUCLEIC ACIDS RESEARCH

Cells expressing FLT3/ITD mutations exhibit elevated repair errors generated through alternative NHEJ pathways: implications for genomic instability and therapy

(2010) J. Fan et al.   BLOOD

BCR-ABL promotes the frequency of mutagenic single-strand annealing DNA repair

(2009) M. S. Fernandes et al.   BLOOD

Up-regulation of WRN and DNA ligase III  in chronic myeloid leukemia: consequences for the repair of DNA double-strand breaks

(2008) A. Sallmyr et al.   BLOOD

Translation of the Philadelphia chromosome into therapy for CML

(2008) B. J. Druker   BLOOD

Genomic instability in myeloid malignancies: Increased reactive oxygen species (ROS), DNA double strand breaks (DSBs) and error-prone repair

(2008) Annahita Sallmyr et al.   CANCER LETTERS