Identification and characterization of intracellular proteins that bind oligonucleotides with phosphorothioate linkages

Phosphorothioate oligonucleotides can displaceNEAT1RNA and form nuclear paraspeckle-like structures

(2014) Wen Shen et al.   NUCLEIC ACIDS RESEARCH

TCP1 complex proteins interact with phosphorothioate oligonucleotides and can co-localize in oligonucleotide-induced nuclear bodies in mammalian cells

(2014) Xue-hai Liang et al.   NUCLEIC ACIDS RESEARCH

Defining the Factors That Contribute to On-Target Specificity of Antisense Oligonucleotides

(2014) Walt F. Lima et al.   PLoS One

Antisense Oligonucleotides Capable of Promoting Specific Target mRNA Reduction via Competing RNase H1-Dependent and Independent Mechanisms

(2014) Timothy A. Vickers et al.   PLoS One

Transfection of siRNAs can alter miRNA levels and trigger non-specific protein degradation in mammalian cells

(2013) Xue-hai Liang et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

RNA helicase A is not required for RISC activity

(2013) Xue-hai Liang et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

Annexin A2 Heterotetramer: Structure and Function

(2013) Alamelu Bharadwaj et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Human RNase H1 Is Associated with Protein P32 and Is Involved in Mitochondrial Pre-rRNA Processing

(2013) Hongjiang Wu et al.   PLoS One

Receptors, endocytosis, and trafficking: the biological basis of targeted delivery of antisense and siRNA oligonucleotides

(2012) R. L. Juliano et al.   JOURNAL OF DRUG TARGETING

Cellular Uptake and Intracellular Trafficking of Antisense and siRNA Oligonucleotides

(2011) Rudolph L. Juliano et al.   BIOCONJUGATE CHEMISTRY

RNA Chaperone Activity of Human La Protein Is Mediated by Variant RNA Recognition Motif

(2011) Amir R. Naeeni et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Silencing disease genes in the laboratory and the clinic

(2011) Jonathan K Watts et al.   JOURNAL OF PATHOLOGY

Depletion of key protein components of the RISC pathway impairs pre-ribosomal RNA processing

(2011) Xue-hai Liang et al.   NUCLEIC ACIDS RESEARCH

Mechanisms of single-stranded phosphorothioate modified antisense oligonucleotide accumulation in hepatocytes

(2011) Erich Koller et al.   NUCLEIC ACIDS RESEARCH

RNA Targeting Therapeutics: Molecular Mechanisms of Antisense Oligonucleotides as a Therapeutic Platform

(2010) C. Frank Bennett et al.   Annual Review of Pharmacology and Toxicology

Efficient and specific knockdown of small non-coding RNAs in mammalian cells and in mice

(2010) Xue-hai Liang et al.   NUCLEIC ACIDS RESEARCH

Sub1/PC4 a chromatin associated protein with multiple functions in transcription

(2010) Christine Conesa et al.   RNA Biology

Involvement of p54(nrb), a PSF partner protein, in DNA double-strand break repair and radioresistance

(2009) Shuyi Li et al.   NUCLEIC ACIDS RESEARCH

Efficient gene silencing by delivery of locked nucleic acid antisense oligonucleotides, unassisted by transfection reagents

(2009) C. A. Stein et al.   NUCLEIC ACIDS RESEARCH

Annexin A2 Binding to Endosomes and Functions in Endosomal Transport Are Regulated by Tyrosine 23 Phosphorylation

(2008) Etienne Morel et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Nucleophosmin Serves as a Rate-Limiting Nuclear Export Chaperone for the Mammalian Ribosome

(2008) L. B. Maggi et al.   MOLECULAR AND CELLULAR BIOLOGY