A playbook for developing disease-resistant crops through immune receptor identification and transfer

A five-transgene cassette confers broad-spectrum resistance to a fungal rust pathogen in wheat

(2021) Ming Luo et al.   NATURE BIOTECHNOLOGY

Plant “helper” immune receptors are Ca2+-permeable nonselective cation channels

(2021) Pierre Jacob et al.   SCIENCE

Evolution of Plant NLRs: From Natural History to Precise Modifications

(2020) Janina Tamborski et al.   Annual Review of Plant Biology

The pan-genome effector-triggered immunity landscape of a host-pathogen interaction

(2020) Bradley Laflamme et al.   SCIENCE

Origin and Diversity of Plant Receptor-Like Kinases

(2020) Anne Dievart et al.   Annual Review of Plant Biology

Convergent Loss of an EDS1/PAD4 Signaling Pathway in Several Plant Lineages Reveals Co-evolved Components of Plant Immunity and Drought Response

(2020) Erin Baggs et al.   PLANT CELL

The Immune Receptor Roq1 Confers Resistance to the Bacterial Pathogens Xanthomonas, Pseudomonas syringae, and Ralstonia in Tomato

(2020) Nicholas C. Thomas et al.   Frontiers in Plant Science

The evolving landscape of cell surface pattern recognition across plant immune networks

(2020) Adam D Steinbrenner   CURRENT OPINION IN PLANT BIOLOGY

Near-isogenic soybean lines carrying Asian soybean rust resistance genes for practical pathogenicity validation

(2020) Takeshi Kashiwa et al.   Scientific Reports

What is the Molecular Basis of Nonhost Resistance?

(2020) Ralph Panstruga et al.   MOLECULAR PLANT-MICROBE INTERACTIONS

A highly differentiated region of wheat chromosome 7AL encodes a Pm1a immune receptor that recognizes its corresponding AvrPm1a effector from Blumeria graminis

(2020) Tim Hewitt et al.   NEW PHYTOLOGIST

A receptor-like protein mediates plant immune responses to herbivore-associated molecular patterns

(2020) Adam D. Steinbrenner et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Progress in Developing Bacterial Spot Resistance in Tomato

(2019) Sadikshya Sharma et al.   Agronomy-Basel

Transgressive segregation reveals mechanisms of Arabidopsis immunity to Brassica-infecting races of white rust (Albugo candida)

(2019) Volkan Cevik et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Resistance gene cloning from a wild crop relative by sequence capture and association genetics

(2019) Sanu Arora et al.   NATURE BIOTECHNOLOGY

Engineering a Decoy Substrate in Soybean to Enable Recognition of the Soybean Mosaic Virus NIa Protease

(2019) Matthew Helm et al.   MOLECULAR PLANT-MICROBE INTERACTIONS

Two Arabidopsis Receptor-like Cytoplasmic Kinases SZE1 and SZE2 Associate with the ZAR1–ZED1 Complex and Are Required for Effector-Triggered Immunity

(2019) Cheng Liu et al.   Molecular Plant

Multiple pairs of allelic MLA immune receptor-powdery mildew AVRA effectors argue for a direct recognition mechanism

(2019) Isabel ML Saur et al.   eLife

Expecting the unexpected: factors influencing the emergence of fungal and oomycete plant pathogens

(2019) Pilar Corredor‐Moreno et al.   NEW PHYTOLOGIST

An EDS1-SAG101 Complex is Essential for TNL-mediated Immunity in Nicotiana benthamiana

(2019) Johannes Gantner et al.   PLANT CELL

A coevolved EDS1-SAG101-NRG1 module mediates cell death signaling by TIR-domain immune receptors

(2019) Dmitry Lapin et al.   PLANT CELL

TurboID-based proximity labeling reveals that UBR7 is a regulator of N NLR immune receptor-mediated immunity

(2019) Yongliang Zhang et al.   Nature Communications

A Species-Wide Inventory of NLR Genes and Alleles in Arabidopsis thaliana

(2019) Anna-Lena Van de Weyer et al.   CELL

Help wanted: helper NLRs and plant immune responses

(2019) Lance M Jubic et al.   CURRENT OPINION IN PLANT BIOLOGY

NLR singletons, pairs, and networks: evolution, assembly, and regulation of the intracellular immunoreceptor circuitry of plants

(2019) Hiroaki Adachi et al.   CURRENT OPINION IN PLANT BIOLOGY

Protein engineering expands the effector recognition profile of a rice NLR immune receptor

(2019) Juan Carlos De la Concepcion et al.   eLife

An N-terminal motif in NLR immune receptors is functionally conserved across distantly related plant species

(2019) Hiroaki Adachi et al.   eLife

Rpa1 mediates an immune response to avrRpm1 Psa and confers resistance against Pseudomonas syringae pv. actinidiae

(2019) Minsoo Yoon et al.   PLANT JOURNAL

Development and validation of IPM strategies for the cultivation of cisgenically modified late blight resistant potato

(2018) Geert J.T. Kessel et al.   EUROPEAN JOURNAL OF AGRONOMY

Pm21 from Haynaldia villosa Encodes a CC-NBS-LRR Protein Conferring Powdery Mildew Resistance in Wheat

(2018) Liping Xing et al.   Molecular Plant

Defended to the Nines: 25 Years of Resistance Gene Cloning Identifies Nine Mechanisms for R Protein Function

(2018) Jiorgos Kourelis et al.   PLANT CELL

Roles of receptor-like cytoplasmic kinase VII members in pattern-triggered immune signaling

(2018) Shaofei Rao et al.   PLANT PHYSIOLOGY

Plant NLRs: From discovery to application

(2018) Paul Kapos et al.   PLANT SCIENCE

Receptor networks underpin plant immunity

(2018) Chih-Hang Wu et al.   SCIENCE

Genome Editing: Targeting Susceptibility Genes for Plant Disease Resistance

(2018) Syed Shan-e-Ali Zaidi et al.   TRENDS IN BIOTECHNOLOGY

Leucine-rich repeat receptor-like gene screen reveals that Nicotiana RXEG1 regulates glycoside hydrolase 12 MAMP detection

(2018) Yan Wang et al.   Nature Communications

An extracellular network of Arabidopsis leucine-rich repeat receptor kinases

(2018) Elwira Smakowska-Luzan et al.   NATURE

Efficient proximity labeling in living cells and organisms with TurboID

(2018) Tess C Branon et al.   NATURE BIOTECHNOLOGY

Using forward genetics in Nicotiana benthamiana to uncover the immune signaling pathway mediating recognition of the Xanthomonas perforans effector XopJ4

(2018) Alex Schultink et al.   NEW PHYTOLOGIST

Expression of the Arabidopsis thaliana immune receptor EFR in Medicago truncatula reduces infection by a root pathogenic bacterium, but not nitrogen-fixing rhizobial symbiosis

(2018) Sebastian Pfeilmeier et al.   PLANT BIOTECHNOLOGY JOURNAL

Differential regulation of TNL-mediated immune signaling by redundant helper CNLs

(2018) Zhongshou Wu et al.   NEW PHYTOLOGIST

Diverse NLR immune receptors activate defence via the RPW8-NLR NRG1

(2018) Baptiste Castel et al.   NEW PHYTOLOGIST

Stacking three late blight resistance genes from wild species directly into African highland potato varieties confers complete field resistance to local blight races

(2018) Marc Ghislain et al.   PLANT BIOTECHNOLOGY JOURNAL

NRG1 functions downstream of EDS1 to regulate TIR-NLR-mediated plant immunity in Nicotiana benthamiana

(2018) Tiancong Qi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Roq1 mediates recognition of the Xanthomonas and Pseudomonas effector proteins XopQ and HopQ1

(2017) Alex Schultink et al.   PLANT JOURNAL

NLR network mediates immunity to diverse plant pathogens

(2017) Chih-Hang Wu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Epigenetic regulation of antagonistic receptors confers rice blast resistance with yield balance

(2017) Yiwen Deng et al.   SCIENCE

Protein-protein interactions in the RPS4/RRS1 immune receptor complex

(2017) Sung Un Huh et al.   PLoS Pathogens

Rapid cloning of disease-resistance genes in plants using mutagenesis and sequence capture

(2016) Burkhard Steuernagel et al.   NATURE BIOTECHNOLOGY

Asian soybean rust in Brazil: past, present, and future

(2016) Cláudia Vieira Godoy et al.   PESQUISA AGROPECUARIA BRASILEIRA

Rapid emergence of pathogens in agro-ecosystems: global threats to agricultural sustainability and food security

(2016) Bruce A. McDonald et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

NbCSPR underlies age-dependent immune responses to bacterial cold shock protein inNicotiana benthamiana

(2016) Isabel M. L. Saur et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Allelic barley MLA immune receptors recognize sequence-unrelated avirulence effectors of the powdery mildew pathogen

(2016) Xunli Lu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Detection of the plant parasite Cuscuta reflexa by a tomato cell surface receptor

(2016) Volker Hegenauer et al.   SCIENCE

Intracellular innate immune surveillance devices in plants and animals

(2016) J. D. G. Jones et al.   SCIENCE

SERKing Coreceptors for Receptors

(2016) Xiyu Ma et al.   TRENDS IN PLANT SCIENCE

The number of known plants species in the world and its annual increase

(2016) MAARTEN J.M. CHRISTENHUSZ et al.   Phytotaxa

The Decoy Substrate of a Pathogen Effector and a Pseudokinase Specify Pathogen-Induced Modified-Self Recognition and Immunity in Plants

(2015) Guoxun Wang et al.   Cell Host & Microbe

Efficient Virus-Mediated Genome Editing in Plants Using the CRISPR/Cas9 System

(2015) Zahir Ali et al.   Molecular Plant

Tomato I2 Immune Receptor Can Be Engineered to Confer Partial Resistance to the OomycetePhytophthora infestansin Addition to the FungusFusarium oxysporum

(2015) Artemis Giannakopoulou et al.   MOLECULAR PLANT-MICROBE INTERACTIONS

A geminivirus-based guide RNA delivery system for CRISPR/Cas9 mediated plant genome editing

(2015) Kangquan Yin et al.   Scientific Reports

Single Amino Acid Mutations in the Potato Immune Receptor R3a Expand Response to Phytophthora Effectors

(2014) María Eugenia Segretin et al.   MOLECULAR PLANT-MICROBE INTERACTIONS

The kinase LYK5 is a major chitin receptor in Arabidopsis and forms a chitin-induced complex with related kinase CERK1

(2014) Yangrong Cao et al.   eLife

A novel conserved mechanism for plant NLR protein pairs: the “integrated decoy” hypothesis

(2014) Stella Cesari et al.   Frontiers in Plant Science

Structural Basis for Signaling by Exclusive EDS1 Heteromeric Complexes with SAG101 or PAD4 in Plant Innate Immunity

(2013) Stephan Wagner et al.   Cell Host & Microbe

The Rice Resistance Protein Pair RGA4/RGA5 Recognizes the Magnaporthe oryzae Effectors AVR-Pia and AVR1-CO39 by Direct Binding

(2013) S. Cesari et al.   PLANT CELL

Resistance gene enrichment sequencing (RenSeq) enables reannotation of the NB-LRR gene family from sequenced plant genomes and rapid mapping of resistance loci in segregating populations

(2013) Florian Jupe et al.   PLANT JOURNAL

Interfamily Transfer of Dual NB-LRR Genes Confers Resistance to Multiple Pathogens

(2013) Mari Narusaka et al.   PLoS One

Receptor-like kinase SOBIR1/EVR interacts with receptor-like proteins in plant immunity against fungal infection

(2013) T. W. H. Liebrand et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Rapidly evolving R genes in diverse grass species confer resistance to rice blast disease

(2013) S. Yang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Arabidopsis ZED1 pseudokinase is required for ZAR1-mediated immunity induced by the Pseudomonas syringae type III effector HopZ1a

(2013) J. D. Lewis et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Interfamily Transfer of Tomato Ve1 Mediates Verticillium Resistance in Arabidopsis

(2011) E. F. Fradin et al.   PLANT PHYSIOLOGY

Functional stacking of three resistance genes against Phytophthora infestans in potato

(2011) Suxian Zhu et al.   TRANSGENIC RESEARCH

Interfamily transfer of a plant pattern-recognition receptor confers broad-spectrum bacterial resistance

(2010) Séverine Lacombe et al.   NATURE BIOTECHNOLOGY

BAK1 is required for the attenuation of ethylene-inducing xylanase (Eix)-induced defense responses by the decoy receptor LeEix1

(2010) Maya Bar et al.   PLANT JOURNAL

Allele-Specific Virulence Attenuation of the Pseudomonas syringae HopZ1a Type III Effector via the Arabidopsis ZAR1 Resistance Protein

(2010) Jennifer D. Lewis et al.   PLoS Genetics