Circular Aqueous Fmoc/t‐Bu Solid‐Phase Peptide Synthesis

Cost-Effective Flow Peptide Synthesis: Metamorphosis of HPLC

(2021) Viktor Farkas et al.   ORGANIC PROCESS RESEARCH & DEVELOPMENT

Chemistry 2030: A Roadmap for a New Decade

(2021) Javier Garcia‐Martinez   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Trends in peptide drug discovery

(2021) Markus Muttenthaler et al.   NATURE REVIEWS DRUG DISCOVERY

2020 FDA TIDES (Peptides and Oligonucleotides) Harvest

(2021) Othman Al Musaimi et al.   Pharmaceuticals

Strategies to Tackle the Waste Water from α-Tocopherol-Derived Surfactant Chemistry

(2021) Christoph Krell et al.   ORGANIC PROCESS RESEARCH & DEVELOPMENT

Prebiotic Peptides: Molecular Hubs in the Origin of Life

(2020) Moran Frenkel-Pinter et al.   CHEMICAL REVIEWS

Rethinking chemistry for a circular economy

(2020) Klaus Kümmerer et al.   SCIENCE

Designing for a green chemistry future

(2020) Julie B. Zimmerman et al.   SCIENCE

Challenges and Perspectives in Chemical Synthesis of Highly Hydrophobic Peptides

(2020) Lena K. Mueller et al.   Frontiers in Bioengineering and Biotechnology

Sustainable Peptide Synthesis Enabled by a Transient Protecting Group

(2020) Sascha Knauer et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Assessing the correlation of microscopy‐based and volumetry‐based measurements for resin swelling in a range of potential greener solvents for SPPS

(2020) Jordan Kevin Magtaan et al.   JOURNAL OF PEPTIDE SCIENCE

Synthesis of proteins by automated flow chemistry

(2020) N. Hartrampf et al.   SCIENCE

Investigation of Parameters that Affect Resin Swelling in Green Solvents

(2020) Chidi Amadi‐Kamalu et al.   ChemistryOpen

Chemical Synthesis of Proteins Containing 300 Amino Acids

(2020) Baochang Zhang et al.   CHEMICAL RESEARCH IN CHINESE UNIVERSITIES

Fast Amide Couplings in Water: Extraction, Column Chromatography, and Crystallization Not Required

(2020) Sudripet Sharma et al.   ORGANIC LETTERS

Simple Synthesis of Amides via Their Acid Chlorides in Aqueous TPGS-750-M

(2020) Min Shi et al.   ORGANIC PROCESS RESEARCH & DEVELOPMENT

Taming Troublesome Suzuki–Miyaura Reactions in Water Solution of Surfactants by the Use of Lecithin: A Step beyond the Micellar Model

(2020) Chiara Ceriani et al.   ORGANIC PROCESS RESEARCH & DEVELOPMENT

Mechanochemical Synthesis of Amides with Uronium-Based Coupling Reagents: A Method for Hexa-amidation of Biotin[6]uril

(2020) Tatsiana Dalidovich et al.   ACS Sustainable Chemistry & Engineering

Flow‐based SPPS for protein synthesis: A perspective

(2020) Zachary P. Gates et al.   Peptide Science

Sustainability Challenges in Peptide Synthesis and Purification: From R&D to Production

(2019) Albert Isidro-Llobet et al.   JOURNAL OF ORGANIC CHEMISTRY

Resin Swelling in Mixed Solvents Analysed using Hansen Solubility Parameter Space

(2019) Yanrui Ran et al.   CHEMISTRY-A EUROPEAN JOURNAL

Troubleshooting When Using γ-Valerolactone (GVL) in Green Solid-Phase Peptide Synthesis

(2019) Ashish Kumar et al.   ORGANIC PROCESS RESEARCH & DEVELOPMENT

Green Solvent Mixtures for Solid-Phase Peptide Synthesis: A Dimethylformamide-Free Highly Efficient Synthesis of Pharmaceutical-Grade Peptides

(2019) Lucia Ferrazzano et al.   ACS Sustainable Chemistry & Engineering

OctaGel Resin - A New PEG-PS-based Solid Support for Solid-Phase Peptide Synthesis

(2019) Shaveer Ramkisson et al.   LETTERS IN ORGANIC CHEMISTRY

Synthetic peptide API manufacturing: A mini review of current perspectives for peptide manufacturing

(2018) Jon H. Rasmussen   BIOORGANIC & MEDICINAL CHEMISTRY

Multicomponent self-assembly as a tool to harness new properties from peptides and proteins in material design

(2018) Babatunde O. Okesola et al.   CHEMICAL SOCIETY REVIEWS

Waste-minimised copper-catalysed azide–alkyne cycloaddition in Polarclean as a reusable and safe reaction medium

(2018) Lorenzo Luciani et al.   GREEN CHEMISTRY

TCFH–NMI: Direct Access to N-Acyl Imidazoliums for Challenging Amide Bond Formations

(2018) Gregory L. Beutner et al.   ORGANIC LETTERS

N-Butylpyrrolidinone as Alternative Solvent for Solid-Phase Peptide Synthesis

(2018) John Lopez et al.   ORGANIC PROCESS RESEARCH & DEVELOPMENT

Amidation and esterification of carboxylic acids with amines and phenols by N,N′-diisopropylcarbodiimide: A new approach for amide and ester bond formation in water

(2018) Nadia Fattahi et al.   TETRAHEDRON

Greener solvents for solid-phase synthesis

(2017) Stefan Lawrenson et al.   GREEN CHEMISTRY

The greening of peptide synthesis

(2017) Stefan B. Lawrenson et al.   GREEN CHEMISTRY

Tandem deprotection/coupling for peptide synthesis in water at room temperature

(2017) Margery Cortes-Clerget et al.   GREEN CHEMISTRY

The Current State of Peptide Drug Discovery: Back to the Future?

(2017) Antoine Henninot et al.   JOURNAL OF MEDICINAL CHEMISTRY

A comparative study of amide-bond forming reagents in aqueous media – Substrate scope and reagent compatibility

(2017) Matthew Badland et al.   TETRAHEDRON LETTERS

N-Butylpyrrolidinone as a dipolar aprotic solvent for organic synthesis

(2016) James Sherwood et al.   GREEN CHEMISTRY

A fundamental study of the physicochemical properties of Rhodiasolv®Polarclean: A promising alternative to common and hazardous solvents

(2016) Alena Randová et al.   JOURNAL OF MOLECULAR LIQUIDS

Advances in Fmoc solid-phase peptide synthesis

(2016) Raymond Behrendt et al.   JOURNAL OF PEPTIDE SCIENCE

On-Demand Complex Peptide Synthesis: An Aspirational (and Elusive?) Goal for Peptide Synthesis

(2016) Kenneth E. Schwieter et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Deprotection Reagents in Fmoc Solid Phase Peptide Synthesis: Moving Away from Piperidine?

(2016) Omar Luna et al.   MOLECULES

Effects of Co-solvents on Reactions Run under Micellar Catalysis Conditions

(2016) Christopher M. Gabriel et al.   ORGANIC LETTERS

A General and Practical Alternative to Polar Aprotic Solvents Exemplified on an Amide Bond Formation

(2016) Fabrice Gallou et al.   ORGANIC PROCESS RESEARCH & DEVELOPMENT

Peptide therapeutics: current status and future directions

(2015) Keld Fosgerau et al.   DRUG DISCOVERY TODAY

Amide and Peptide Bond Formation in Water at Room Temperature

(2015) Christopher M. Gabriel et al.   ORGANIC LETTERS

Aqueous microwave-assisted solid-phase peptide synthesis using Fmoc strategy. III: Racemization studies and water-based synthesis of histidine-containing peptides

(2014) Keiko Hojo et al.   AMINO ACIDS

Continuous-Flow Solid-Phase Peptide Synthesis: A Revolutionary Reduction of the Amino Acid Excess

(2014) István M. Mándity et al.   ChemSusChem

High-Efficiency Solid Phase Peptide Synthesis (HE-SPPS)

(2014) Jonathan M. Collins et al.   ORGANIC LETTERS

Solid-phase peptide synthesis: an overview focused on the preparation of biologically relevant peptides

(2014) Jose M. Palomo   RSC Advances

Microwave-assisted solution phase peptide synthesis in neat water

(2013) Amit Mahindra et al.   RSC Advances

Controlled Solid Phase Peptide Bond Formation Using N-Carboxyanhydrides and PEG Resins in Water.

(2013) Rossella De Marco et al.   ACS Sustainable Chemistry & Engineering

Aqueous Microwave-Assisted Solid-Phase Synthesis Using Boc-Amino Acid Nanoparticles

(2013) Keiko Hojo et al.   Applied Sciences-Basel

Aqueous Microwave-Assisted Solid-Phase Peptide Synthesis Using Fmoc Strategy: In-Water Synthesis of "Difficult Sequences"

(2012) Keiko Hojo et al.   PROTEIN AND PEPTIDE LETTERS

Amino Acid-Protecting Groups

(2009) Albert Isidro-Llobet et al.   CHEMICAL REVIEWS

COMU: A Safer and More Effective Replacement for Benzotriazole-Based Uronium Coupling Reagents

(2009) Ayman El-Faham et al.   CHEMISTRY-A EUROPEAN JOURNAL

Solid-phase peptide synthesis using acetonitrile as a solvent in combination with PEG-based resins

(2009) Gerardo A. Acosta et al.   JOURNAL OF PEPTIDE SCIENCE

Solid-Phase Peptide Synthesis in Water Using Microwave-Assisted Heating

(2009) Athanassios S. Galanis et al.   ORGANIC LETTERS

N,N,N′,N′-Tetramethylchloroformamidinium Hexafluorophosphate (TCFH), a Powerful Coupling Reagent for Bioconjugation

(2008) Judit Tulla-Puche et al.   BIOCONJUGATE CHEMISTRY

Bruce Merrifield and solid-phase peptide synthesis: A historical assessment

(2008) Alexander R. Mitchell   BIOPOLYMERS

Morpholine-Based Immonium and Halogenoamidinium Salts as Coupling Reagents in Peptide Synthesis1

(2008) Ayman El-Faham et al.   JOURNAL OF ORGANIC CHEMISTRY