Norethindrone causes cellular and hepatic injury in zebrafish by compromising the metabolic processes associated with antioxidant defence: Insights from metabolomics

Reproductive potential of mosquitofish is reduced by the masculinizing effect of a synthetic progesterone, gestodene: Evidence from morphology, courtship behaviour, ovary histology, sex hormones and gene expressions

(2021) Shanduo Chen et al.   SCIENCE OF THE TOTAL ENVIRONMENT

Metabolomics Provide Sensitive Insights into the Impacts of Low Level Environmental Contamination on Fish Health—A Pilot Study

(2020) Sara M. Long et al.   Metabolites

Gypenosides regulate farnesoid X receptor-mediated bile acid and lipid metabolism in a mouse model of non-alcoholic steatohepatitis

(2020) Hongshan Li et al.   Nutrition & Metabolism

Norethindrone alters mating behaviors, ovary histology, hormone production and transcriptional expression of steroidogenic genes in zebrafish (Danio rerio)

(2020) Liping Hou et al.   ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY

Mechanism of Hydrophobic Bile Acid-Induced Hepatocyte Injury and Drug Discovery

(2020) Shizhang Wei et al.   Frontiers in Pharmacology

The synthetic progestin norethindrone causes thyroid endocrine disruption in adult zebrafish

(2020) Yan-Qiu Liang et al.   COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY C-TOXICOLOGY & PHARMACOLOGY

Lipid peroxidation regulates long-range wound detection through 5-lipoxygenase in zebrafish

(2020) Anushka Katikaneni et al.   NATURE CELL BIOLOGY

Bile Acids and FXR: Novel Targets for Liver Diseases

(2020) Mary Stofan et al.   Frontiers in Medicine

Microplastic accumulation via trophic transfer: Can a predatory crab counter the adverse effects of microplastics by body defence?

(2020) Ting Wang et al.   SCIENCE OF THE TOTAL ENVIRONMENT

Dual Role of Bile Acids on the Biliary Epithelium: Friend or Foe?

(2019) Leonardo Baiocchi et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Adaptive responses of fishes to climate change: Feedback between physiology and behaviour

(2019) Almendra Rodriguez-Dominguez et al.   SCIENCE OF THE TOTAL ENVIRONMENT

Farnesoid X receptor activation induces the degradation of hepatotoxic 1‐deoxysphingolipids in non‐alcoholic fatty liver disease

(2019) Zhibo Gai et al.   LIVER INTERNATIONAL

Nrf2-Keap1 signaling in oxidative and reductive stress

(2018) Ilaria Bellezza et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Stereoselective effects of ibuprofen in adult zebrafish ( Danio rerio ) using UPLC-TOF/MS-based metabolomics

(2018) Yue Song et al.   ENVIRONMENTAL POLLUTION

Lipids and synaptic functions

(2018) Fanny Mochel   JOURNAL OF INHERITED METABOLIC DISEASE

Antioxidant and Cell-Signaling Functions of Hydrogen Sulfide in the Central Nervous System

(2018) Ulfuara Shefa et al.   Oxidative Medicine and Cellular Longevity

Trace analysis of 61 natural and synthetic progestins in river water and sewage effluents by ultra-high performance liquid chromatography–tandem mass spectrometry

(2018) Xiaoyan Shen et al.   WATER RESEARCH

Higher Dietary Arachidonic Acid Levels Improved the Growth Performance, Gonad Development, Nutritional Value, and Antioxidant Enzyme Activities of Adult Sea Urchin (Strongylocentrotus intermedius)

(2018) Rantao Zuo et al.   Journal of Ocean University of China

Redox signaling and unfolded protein response coordinate cell fate decisions under ER stress

(2018) Zhe Zhang et al.   Redox Biology

Rapid masculinization and effects on the liver of female western mosquitofish (Gambusia affinis) by norethindrone

(2018) Liping Hou et al.   CHEMOSPHERE

Mechanisms of bile acid mediated inflammation in the liver

(2017) Man Li et al.   MOLECULAR ASPECTS OF MEDICINE

'Omics' and endocrine-disrupting chemicals — new paths forward

(2017) Carmen Messerlian et al.   Nature Reviews Endocrinology

Promising toxicological biomarkers for the diagnosis of liver injury types: Bile acid metabolic profiles and oxidative stress marker as screening tools in drug development

(2016) Noriko Masubuchi et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Bioaccumulation and metabolomics responses in oysters Crassostrea hongkongensis impacted by different levels of metal pollution

(2016) Chen Cao et al.   ENVIRONMENTAL POLLUTION

A novel approach for estimating the removal efficiencies of endocrine disrupting chemicals and heavy metals in wastewater treatment processes

(2016) Jill M.Y. Chiu et al.   MARINE POLLUTION BULLETIN

Cytoplasmic vacuolization in cell death and survival

(2016) Andrey V. Shubin et al.   Oncotarget

Mitochondrial dysfunction in aging: Much progress but many unresolved questions

(2015) Brendan A.I. Payne et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Executive Summary to EDC-2: The Endocrine Society's Second Scientific Statement on Endocrine-Disrupting Chemicals

(2015) A. C. Gore et al.   ENDOCRINE REVIEWS

Progestins as endocrine disrupters in aquatic ecosystems: Concentrations, effects and risk assessment

(2015) Karl Fent   ENVIRONMENT INTERNATIONAL

The Challenge Presented by Progestins in Ecotoxicological Research: A Critical Review

(2015) Vimal Kumar et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Oxidative damage of hepatopancreas induced by pollution depresses humoral immunity response in the freshwater crayfish Procambarus clarkii

(2015) Keqiang Wei et al.   FISH & SHELLFISH IMMUNOLOGY

Acetyl-l-carnitine increases mitochondrial protein acetylation in the aged rat heart

(2015) Janos Kerner et al.   MECHANISMS OF AGEING AND DEVELOPMENT

Changes in the mitochondrial antioxidant systems in neurodegenerative diseases and acute brain disorders

(2015) Joanna Ruszkiewicz et al.   NEUROCHEMISTRY INTERNATIONAL

Analysis of 21 progestagens in various matrices by ultra-high-performance liquid chromatography tandem mass spectrometry (UHPLC-MS/MS) with diverse sample pretreatment

(2014) Shuang-Shuang Liu et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

The role of gasotransmitters NO, H2S and CO in myocardial ischaemia/reperfusion injury and cardioprotection by preconditioning, postconditioning and remote conditioning

(2014) Ioanna Andreadou et al.   BRITISH JOURNAL OF PHARMACOLOGY

Diversity and function of membrane glycerophospholipids generated by the remodeling pathway in mammalian cells

(2014) Daisuke Hishikawa et al.   JOURNAL OF LIPID RESEARCH

Mfsd2a is a transporter for the essential omega-3 fatty acid docosahexaenoic acid

(2014) Long N. Nguyen et al.   NATURE

Molecular insights into 4-nitrophenol-induced hepatotoxicity in zebrafish: Transcriptomic, histological and targeted gene expression analyses

(2013) Siew Hong Lam et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Targeting the alternative NF-κB pathway in pancreatic cancer: a new direction for therapy?

(2013) Peter Storz   Expert Review of Anticancer Therapy

Molecular mechanisms involved in the protective effect of selenocystine against methylmercury-induced cell death in human HepG2 cells

(2013) Isabel Cordero-Herrera et al.   FOOD AND CHEMICAL TOXICOLOGY

Generation of membrane diversity by lysophospholipid acyltransferases

(2013) H. Shindou et al.   JOURNAL OF BIOCHEMISTRY

Hydrogen Sulfide Protects Against Cellular Senescence via S-Sulfhydration of Keap1 and Activation of Nrf2

(2012) Guangdong Yang et al.   ANTIOXIDANTS & REDOX SIGNALING

S-Carboxymethyl-L-cysteine

(2012) Steve C. Mitchell et al.   DRUG METABOLISM REVIEWS

Mechanism of tissue-specific farnesoid X receptor in suppressing the expression of genes in bile-acid synthesis in mice

(2012) Bo Kong et al.   HEPATOLOGY

Endocrine Disruptors: From Endocrine to Metabolic Disruption

(2011) Cristina Casals-Casas et al.   Annual Review of Physiology

H2S-Induced Sulfhydration of the Phosphatase PTP1B and Its Role in the Endoplasmic Reticulum Stress Response

(2011) N. Krishnan et al.   Science Signaling

Effects of dietary arachidonic acid on growth performance, survival, immune response and tissue fatty acid composition of juvenile Japanese seabass, Lateolabrax japonicus

(2010) Houguo Xu et al.   AQUACULTURE

Reproductive responses in fathead minnow and Japanese medaka following exposure to a synthetic progestin, Norethindrone

(2010) Peter Paulos et al.   AQUATIC TOXICOLOGY

Bile acids decrease intracellular bilirubin levels in the cholestatic liver: implications for bile acid-mediated oxidative stress

(2010) Lucie Muchova et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Integrated, Nontargeted Ultrahigh Performance Liquid Chromatography/Electrospray Ionization Tandem Mass Spectrometry Platform for the Identification and Relative Quantification of the Small-Molecule Complement of Biological Systems

(2009) Anne M. Evans et al.   ANALYTICAL CHEMISTRY

Progestagens for human use, exposure and hazard assessment for the aquatic environment

(2009) Jean-Philippe Besse et al.   ENVIRONMENTAL POLLUTION

Determination and Source Apportionment of Five Classes of Steroid Hormones in Urban Rivers

(2009) Hong Chang et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

H2S Biogenesis by Human Cystathionine γ-Lyase Leads to the Novel Sulfur Metabolites Lanthionine and Homolanthionine and Is Responsive to the Grade of Hyperhomocysteinemia

(2009) Taurai Chiku et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Phospholipids: Key Players in Apoptosis and Immune Regulation

(2009) Ricardo Chaurio et al.   MOLECULES

On-line solid phase extraction and liquid chromatography/tandem mass spectrometry to quantify pharmaceuticals, pesticides and some metabolites in wastewaters, drinking, and surface waters

(2008) Liza Viglino et al.   JOURNAL OF ENVIRONMENTAL MONITORING