Phytochemicals as regulators of Th17/Treg balance in inflammatory bowel diseases
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Title
Phytochemicals as regulators of Th17/Treg balance in inflammatory bowel diseases
Authors
Keywords
Inflammatory bowel disease (IBD), Phytochemicals, Th17/Treg balance, Therapeutic effects, Action mechanism
Journal
BIOMEDICINE & PHARMACOTHERAPY
Volume 141, Issue -, Pages 111931
Publisher
Elsevier BV
Online
2021-07-21
DOI
10.1016/j.biopha.2021.111931
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Note: Only part of the references are listed.- Paeoniflorin ameliorates murine lupus nephritis by increasing CD4+Foxp3+ Treg cells via enhancing mTNFα-TNFR2 pathway
- (2021) Chun-Ling Liang et al. BIOCHEMICAL PHARMACOLOGY
- Curcumin regulates the differentiation of naïve CD4+T cells and activates IL-10 immune modulation against acute lung injury in mice
- (2020) Yu-sen Chai et al. BIOMEDICINE & PHARMACOTHERAPY
- mTOR signaling at the crossroads of environmental signals and T‐cell fate decisions
- (2020) Hongling Huang et al. IMMUNOLOGICAL REVIEWS
- Glycogen synthase kinase‐3 promotes T helper type 17 differentiation by promoting interleukin‐9 production
- (2020) Dongmei Han et al. IMMUNOLOGY
- Histone Deacetylation Inhibitors as Modulators of Regulatory T Cells
- (2020) Andreas von Knethen et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- The Regulatory Effects of mTOR Complexes in the Differentiation and Function of CD4+ T Cell Subsets
- (2020) Peng Wang et al. Journal of Immunology Research
- Paeoniflorin ameliorates ulcerative colitis by modulating the dendritic cell-mediated TH17/Treg balance
- (2020) Kai Zheng et al. INFLAMMOPHARMACOLOGY
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- (2020) Jianhua Gao et al. INTERNATIONAL IMMUNOPHARMACOLOGY
- Baicalin suppresses Th1 and Th17 responses and promotes Treg response to ameliorate sepsis-associated pancreatic injury via the RhoA-ROCK pathway
- (2020) Pingping Liu et al. INTERNATIONAL IMMUNOPHARMACOLOGY
- Inhibition of two-pore channels in antigen-presenting cells promotes the expansion of TNFR2-expressing CD4+Foxp3+ regulatory T cells
- (2020) Tianzhen He et al. Science Advances
- The Function and Role of the Th17/Treg Cell Balance in Inflammatory Bowel Disease
- (2020) Jun-bin Yan et al. Journal of Immunology Research
- Epigoitrin, an Alkaloid From Isatis indigotica, Reduces H1N1 Infection in Stress-Induced Susceptible Model in vivo and in vitro
- (2019) Zhuo Luo et al. Frontiers in Pharmacology
- Resveratrol modulates the gut microbiota to prevent murine colitis development through induction of Tregs and suppression of Th17 cells
- (2019) Haider Rasheed Alrafas et al. JOURNAL OF LEUKOCYTE BIOLOGY
- Effects of resveratrol on Th17 cell-related immune responses under tacrolimus-based immunosuppression
- (2019) Kyoung Chan Doh et al. BMC Complementary and Alternative Medicine
- Plant-Derived Alkaloids: The Promising Disease-Modifying Agents for Inflammatory Bowel Disease
- (2019) Jiao Peng et al. Frontiers in Pharmacology
- Tangeretin promotes regulatory T cell differentiation by inhibiting Notch1/Jagged1 signaling in allergic rhinitis
- (2019) Shan Xu et al. INTERNATIONAL IMMUNOPHARMACOLOGY
- Dihydroartemisinin Regulates the Th/Treg Balance by Inducing Activated CD4+ T cell Apoptosis via Heme Oxygenase-1 Induction in Mouse Models of Inflammatory Bowel Disease
- (2019) Si Chao Yan et al. MOLECULES
- Indole alkaloids indigodoles A–C from aerial parts of Strobilanthes cusia in the traditional Chinese medicine Qing Dai have anti-IL-17 properties
- (2019) Chia-Lin Lee et al. PHYTOCHEMISTRY
- Dietary natural flavonoids treating cancer by targeting aryl hydrocarbon receptor
- (2019) Tian Yang et al. CRITICAL REVIEWS IN TOXICOLOGY
- Indigo Naturalis Suppresses Colonic Oxidative Stress and Th1/Th17 Responses of DSS-Induced Colitis in Mice
- (2019) Hai-tao Xiao et al. Oxidative Medicine and Cellular Longevity
- Berberine improved experimental chronic colitis by regulating interferon-γ- and IL-17A-producing lamina propria CD4+ T cells through AMPK activation
- (2019) Masahiro Takahara et al. Scientific Reports
- Estrogen receptor β activation ameliorates DSS-induced chronic colitis by inhibiting inflammation and promoting Treg differentiation
- (2019) Di Guo et al. INTERNATIONAL IMMUNOPHARMACOLOGY
- Resveratrol Downregulates miR‐31 to Promote T Regulatory Cells during Prevention of TNBS‐Induced Colitis
- (2019) Haider Rasheed Alrafas et al. MOLECULAR NUTRITION & FOOD RESEARCH
- Cambogin suppresses dextran sulphate sodium-induced colitis by enhancing Treg cell stability and function
- (2018) Yue Lu et al. BRITISH JOURNAL OF PHARMACOLOGY
- Th17 plasticity and its relevance to inflammatory bowel disease
- (2018) Aito Ueno et al. JOURNAL OF AUTOIMMUNITY
- Norisoboldine, a natural AhR agonist, promotes Treg differentiation and attenuates colitis via targeting glycolysis and subsequent NAD+/SIRT1/SUV39H1/H3K9me3 signaling pathway
- (2018) Qi Lv et al. Cell Death & Disease
- Berberine Regulates Treg/Th17 Balance to Treat Ulcerative Colitis Through Modulating the Gut Microbiota in the Colon
- (2018) Huantian Cui et al. Frontiers in Pharmacology
- STAT5 and TET2 Cooperate to Regulate FOXP3-TSDR Demethylation in CD4+ T Cells of Patients with Colorectal Cancer
- (2018) Hulin Ma et al. Journal of Immunology Research
- Modulation of Regulatory T Cell Activity by TNF Receptor Type II-Targeting Pharmacological Agents
- (2018) Huimin Zou et al. Frontiers in Immunology
- Alpinetin exerts anti-colitis efficacy by activating AhR, regulating miR-302/DNMT-1/CREB signals, and therefore promoting Treg differentiation
- (2018) Qi Lv et al. Cell Death & Disease
- An RORγt Oral Inhibitor Modulates IL-17 Responses in Peripheral Blood and Intestinal Mucosa of Crohn's Disease Patients
- (2018) Helena Bassolas-Molina et al. Frontiers in Immunology
- Resveratrol Attenuates Allergic Asthma and Associated Inflammation in the Lungs Through Regulation of miRNA-34a That Targets FoxP3 in Mice
- (2018) Esraah Alharris et al. Frontiers in Immunology
- Refractory pouchitis improves after administration of the green tea polyphenol EGCG: a retrospective review
- (2017) Minesh Mehta et al. INTERNATIONAL JOURNAL OF COLORECTAL DISEASE
- Therapeutic Potential of Targeting the Th17/Treg Axis in Autoimmune Disorders
- (2017) Patrizia Fasching et al. MOLECULES
- Resveratrol and inflammatory bowel disease: the evidence so far
- (2017) Sandra Nunes et al. NUTRITION RESEARCH REVIEWS
- Madecassic acid, the contributor to the anti-colitis effect of madecassoside, enhances the shift of Th17 toward Treg cells via the PPARγ/AMPK/ACC1 pathway
- (2017) Xiaotian Xu et al. Cell Death & Disease
- Notch Signaling in T Helper Cell Subsets: Instructor or Unbiased Amplifier?
- (2017) Irma Tindemans et al. Frontiers in Immunology
- Nanoparticle curcumin ameliorates experimental colitis via modulation of gut microbiota and induction of regulatory T cells
- (2017) Masashi Ohno et al. PLoS One
- Potential of Plant-sourced Phenols for Inflammatory Bowel Disease
- (2017) Hai-tao Xiao et al. CURRENT MEDICINAL CHEMISTRY
- Resveratrol Supplementation and Oxidative/Anti-Oxidative Status in Patients with Ulcerative Colitis: A Randomized, Double-Blind, Placebo-controlled Pilot Study
- (2016) Maryam Samsamikor et al. ARCHIVES OF MEDICAL RESEARCH
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- (2016) Xusheng Yuan et al. BIOCHEMICAL PHARMACOLOGY
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- (2016) Sascha Rutz et al. CYTOKINE & GROWTH FACTOR REVIEWS
- Paeoniflorin inhibits imiquimod-induced psoriasis in mice by regulating Th17 cell response and cytokine secretion
- (2016) Jingxia Zhao et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- Mangiferin corrects the imbalance of Th17/Treg cells in mice with TNBS-induced colitis
- (2016) Su-Min Lim et al. INTERNATIONAL IMMUNOPHARMACOLOGY
- Norisoboldine, an isoquinoline alkaloid, acts as an aryl hydrocarbon receptor ligand to induce intestinal Treg cells and thereby attenuate arthritis
- (2016) Bei Tong et al. INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY
- Epigallocatechin-3-gallate ameliorates autoimmune arthritis by reciprocal regulation of T helper-17 regulatory T cells and inhibition of osteoclastogenesis by inhibiting STAT3 signaling
- (2016) Seon-Yeong Lee et al. JOURNAL OF LEUKOCYTE BIOLOGY
- Halofuginone reduces the inflammatory responses of DSS-induced colitis through metabolic reprogramming
- (2016) Jing Liu et al. Molecular BioSystems
- Berberine ameliorates chronic relapsing dextran sulfate sodium-induced colitis in C57BL/6 mice by suppressing Th17 responses
- (2016) Yan-hong Li et al. PHARMACOLOGICAL RESEARCH
- Curcumin improves regulatory T cells in gut-associated lymphoid tissue of colitis mice
- (2016) Hai-Mei Zhao et al. WORLD JOURNAL OF GASTROENTEROLOGY
- Disrupted regulatory T cell homeostasis in inflammatory bowel diseases
- (2016) Christophe Pedros WORLD JOURNAL OF GASTROENTEROLOGY
- Arctigenin functions as a selective agonist of estrogen receptor β to restrict mTORC1 activation and consequent Th17 differentiation
- (2016) Xin Wu et al. Oncotarget
- Anti-Inflammatory Effects of Resveratrol in Patients with Ulcerative Colitis: A Randomized, Double-Blind, Placebo-controlled Pilot Study
- (2015) Maryam Samsami-kor et al. ARCHIVES OF MEDICAL RESEARCH
- Arctigenin exerts anti-colitis efficacy through inhibiting the differentiation of Th1 and Th17 cells via an mTORC1-dependent pathway
- (2015) Xin Wu et al. BIOCHEMICAL PHARMACOLOGY
- The role of nuclear receptors in regulation of Th17/Treg biology and its implications for diseases
- (2015) Benjamin V. Park et al. Cellular & Molecular Immunology
- Anti-inflammatory effects of ginsenoside Rg1 and its metabolites ginsenoside Rh1 and 20(S)-protopanaxatriol in mice with TNBS-induced colitis
- (2015) Sang-Yun Lee et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- Oleanolic acid ameliorates dextran sodium sulfate-induced colitis in mice by restoring the balance of Th17/Treg cells and inhibiting NF-κB signaling pathway
- (2015) Geum-Dan Kang et al. INTERNATIONAL IMMUNOPHARMACOLOGY
- Timosaponin AIII and its metabolite sarsasapogenin ameliorate colitis in mice by inhibiting NF-κB and MAPK activation and restoring Th17/Treg cell balance
- (2015) Su-Min Lim et al. INTERNATIONAL IMMUNOPHARMACOLOGY
- Norisoboldine ameliorates DSS-induced ulcerative colitis in mice through induction of regulatory T cells in colons
- (2015) Qi Lv et al. INTERNATIONAL IMMUNOPHARMACOLOGY
- Ocotillol, a Majonoside R2 Metabolite, Ameliorates 2,4,6-Trinitrobenzenesulfonic Acid-Induced Colitis in Mice by Restoring the Balance of Th17/Treg Cells
- (2015) Sang-Yun Lee et al. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
- Estradiol Inhibits Th17 Cell Differentiation through Inhibition ofRORγTTranscription by Recruiting the ERα/REA Complex to Estrogen Response Elements of theRORγTPromoter
- (2015) Rong-Yi Chen et al. JOURNAL OF IMMUNOLOGY
- Berberine ameliorates TNBS induced colitis by inhibiting inflammatory responses and Th1/Th17 differentiation
- (2015) Chengzhen Li et al. MOLECULAR IMMUNOLOGY
- Regulatory T-cell depletion in the gut caused by integrin β7 deficiency exacerbates DSS colitis by evoking aberrant innate immunity
- (2015) H L Zhang et al. Mucosal Immunology
- The global burden of IBD: from 2015 to 2025
- (2015) Gilaad G. Kaplan Nature Reviews Gastroenterology & Hepatology
- Effect of resveratrol on Treg/Th17 signaling and ulcerative colitis treatment in mice
- (2015) Jun Yao WORLD JOURNAL OF GASTROENTEROLOGY
- Epigallocatechin-3-gallate-induced inhibition of interleukin-6 release and adjustment of the regulatory T/T helper 17 cell balance in the treatment of colitis in mice
- (2015) ZHENGLEI XU et al. Experimental and Therapeutic Medicine
- Promotion of regulatory T cell induction by immunomodulatory herbal medicine licorice and its two constituents
- (2015) Ao Guo et al. Scientific Reports
- Inflammatory Bowel Disease: Genetics, Epigenetics, and Pathogenesis
- (2015) Italia Loddo et al. Frontiers in Immunology
- Baicalin attenuates TNBS-induced colitis in rats by modulating the Th17/Treg paradigm
- (2014) Ying Zou et al. ARCHIVES OF PHARMACAL RESEARCH
- Th17 and regulatory T cell balance in autoimmune and inflammatory diseases
- (2014) Mélissa Noack et al. AUTOIMMUNITY REVIEWS
- Inhibiting RORγt/Th17 axis for autoimmune disorders
- (2014) Fujio Isono et al. DRUG DISCOVERY TODAY
- Treg functional stability and its responsiveness to the microenvironment
- (2014) Joseph Barbi et al. IMMUNOLOGICAL REVIEWS
- Andrographolide Suppresses IL-6/Stat3 Signaling in Peripheral Blood Mononuclear Cells from Patients with Chronic Rhinosinusitis with Nasal Polyps
- (2014) Wei Kou et al. INFLAMMATION
- Elevated levels of Th17 cells and Th17-related cytokines are associated with disease activity in patients with inflammatory bowel disease
- (2014) Wenyu Jiang et al. INFLAMMATION RESEARCH
- Andrographolide sulfonate ameliorates experimental colitis in mice by inhibiting Th1/Th17 response
- (2014) Wen Liu et al. INTERNATIONAL IMMUNOPHARMACOLOGY
- Halofuginone-Induced Amino Acid Starvation Regulates Stat3-Dependent Th17 Effector Function and Reduces Established Autoimmune Inflammation
- (2014) T. J. Carlson et al. JOURNAL OF IMMUNOLOGY
- A Natural Flavonoid Glucoside, Icariin, Regulates Th17 and Alleviates Rheumatoid Arthritis in a Murine Model
- (2014) Liqun Chi et al. MEDIATORS OF INFLAMMATION
- Targeting sirtuin-1 alleviates experimental autoimmune colitis by induction of Foxp3+ T-regulatory cells
- (2014) T Akimova et al. Mucosal Immunology
- Extracellular Adenosine-Mediated Modulation of Regulatory T Cells
- (2014) Akio Ohta et al. Frontiers in Immunology
- Indoles mitigate the development of experimental autoimmune encephalomyelitis by induction of reciprocal differentiation of regulatory T cells and Th17 cells
- (2013) Michael Rouse et al. BRITISH JOURNAL OF PHARMACOLOGY
- Novel immunoregulatory properties of EGCG on reducing inflammation in EAE
- (2013) Hong Nie Frontiers in Bioscience-Landmark
- Inhibition of Th1/Th17 responses via suppression of STAT1 and STAT3 activation contributes to the amelioration of murine experimental colitis by a natural flavonoid glucoside icariin
- (2012) Feifei Tao et al. BIOCHEMICAL PHARMACOLOGY
- Dietary Flavonoid Naringenin Induces Regulatory T Cells via an Aryl Hydrocarbon Receptor Mediated Pathway
- (2012) Hsi-Kai Wang et al. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
- Dihydroartemisinin Ameliorates Inflammatory Disease by Its Reciprocal Effects on Th and Regulatory T Cell Function via Modulating the Mammalian Target of Rapamycin Pathway
- (2012) Yan G. Zhao et al. JOURNAL OF IMMUNOLOGY
- Green tea epigallocatechin-3-gallate modulates differentiation of naïve CD4+ T cells into specific lineage effector cells
- (2012) Junpeng Wang et al. JOURNAL OF MOLECULAR MEDICINE-JMM
- 3,3′-Diindolylmethane alleviates oxazolone-induced colitis through Th2/Th17 suppression and Treg induction
- (2012) Zhen Huang et al. MOLECULAR IMMUNOLOGY
- Ustekinumab Induction and Maintenance Therapy in Refractory Crohn's Disease
- (2012) William J. Sandborn et al. NEW ENGLAND JOURNAL OF MEDICINE
- MicroRNA-155 Is Essential for the T Cell-Mediated Control of Helicobacter pylori Infection and for the Induction of Chronic Gastritis and Colitis
- (2011) M. Oertli et al. JOURNAL OF IMMUNOLOGY
- Histone Deacetylase 6 and Heat Shock Protein 90 Control the Functions of Foxp3+ T-Regulatory Cells
- (2011) E. F. de Zoeten et al. MOLECULAR AND CELLULAR BIOLOGY
- Adalimumab treatment in Crohn's disease does not induce early changes in regulatory T cells
- (2011) Anders Dige et al. SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY
- The increased mucosal mRNA expressions of complement C3 and interleukin-17 in inflammatory bowel disease
- (2010) T. Sugihara et al. CLINICAL AND EXPERIMENTAL IMMUNOLOGY
- Glycogen Synthase Kinase-3 Is an Early Determinant in the Differentiation of Pathogenic Th17 Cells
- (2010) E. Beurel et al. JOURNAL OF IMMUNOLOGY
- Triptolide ameliorates IL-10-deficient mice colitis by mechanisms involving suppression of IL-6/STAT3 signaling pathway and down-regulation of IL-17
- (2010) Yi Li et al. MOLECULAR IMMUNOLOGY
- Amelioration of experimental autoimmune encephalomyelitis by curcumin treatment through inhibition of IL-17 production
- (2009) Lin Xie et al. INTERNATIONAL IMMUNOPHARMACOLOGY
- Berberine Differentially Modulates the Activities of ERK, p38 MAPK, and JNK to Suppress Th17 and Th1 T Cell Differentiation in Type 1 Diabetic Mice
- (2009) Guoliang Cui et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Notch1 and TGF 1 cooperatively regulate Foxp3 expression and the maintenance of peripheral regulatory T cells
- (2008) J. B. Samon et al. BLOOD
- Triptolide Inhibits the Differentiation of Th17 cells and Suppresses Collagen-induced Arthritis
- (2008) Y. Wang et al. SCANDINAVIAN JOURNAL OF IMMUNOLOGY
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