Madecassic acid, the contributor to the anti-colitis effect of madecassoside, enhances the shift of Th17 toward Treg cells via the PPARγ/AMPK/ACC1 pathway
Published 2017 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Madecassic acid, the contributor to the anti-colitis effect of madecassoside, enhances the shift of Th17 toward Treg cells via the PPARγ/AMPK/ACC1 pathway
Authors
Keywords
-
Journal
Cell Death & Disease
Volume 8, Issue 3, Pages e2723-e2723
Publisher
Springer Nature
Online
2017-03-30
DOI
10.1038/cddis.2017.150
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Chemical structures, production and enzymatic transformations of sapogenins and saponins from Centella asiatica (L.) Urban
- (2016) Robert Azerad FITOTERAPIA
- Emerging concepts of T cell metabolism as a target of immunotherapy
- (2016) Chih-Hao Chang et al. NATURE IMMUNOLOGY
- Metformin attenuates graft-versus-host disease via restricting mammalian target of rapamycin/signal transducer and activator of transcription 3 and promoting adenosine monophosphate–activated protein kinase-autophagy for the balance between T helper 17 and Tregs
- (2016) Min-Jung Park et al. Translational Research
- Intestinal interleukin-10 mobilization as a contributor to the anti-arthritis effect of orally administered madecassoside: A unique action mode of saponin compounds with poor bioavailability
- (2015) Ting Wang et al. BIOCHEMICAL PHARMACOLOGY
- Arctigenin exerts anti-colitis efficacy through inhibiting the differentiation of Th1 and Th17 cells via an mTORC1-dependent pathway
- (2015) Xin Wu et al. BIOCHEMICAL PHARMACOLOGY
- A Metabolic Switch for Th17 Pathogenicity
- (2015) Fred P. Davis et al. CELL
- The role of nuclear receptors in regulation of Th17/Treg biology and its implications for diseases
- (2015) Benjamin V. Park et al. Cellular & Molecular Immunology
- Identification and characterisation of a prototype for a new class of competitive PPARγ antagonists
- (2015) Tilo Knape et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- Th17 cells transdifferentiate into regulatory T cells during resolution of inflammation
- (2015) Nicola Gagliani et al. NATURE
- Epidemiology and risk factors for IBD
- (2015) Ashwin N. Ananthakrishnan Nature Reviews Gastroenterology & Hepatology
- Immunopathogenesis of IBD: current state of the art
- (2015) Heitor S. P. de Souza et al. Nature Reviews Gastroenterology & Hepatology
- Exploring the emerging complexity in transcriptional regulation of energy homeostasis
- (2015) Adelheid Lempradl et al. NATURE REVIEWS GENETICS
- Targeting T cell metabolism for therapy
- (2015) David O'Sullivan et al. TRENDS IN IMMUNOLOGY
- Obesity Drives Th17 Cell Differentiation by Inducing the Lipid Metabolic Kinase, ACC1
- (2015) Yusuke Endo et al. Cell Reports
- The Treg/Th17 Axis: A Dynamic Balance Regulated by the Gut Microbiome
- (2015) Sara Omenetti et al. Frontiers in Immunology
- Diagnosis and classification of ulcerative colitis
- (2014) Karsten Conrad et al. AUTOIMMUNITY REVIEWS
- Th17 and regulatory T cell balance in autoimmune and inflammatory diseases
- (2014) Mélissa Noack et al. AUTOIMMUNITY REVIEWS
- Agonistic induction of PPARγ reverses cigarette smoke–induced emphysema
- (2014) Ming Shan et al. JOURNAL OF CLINICAL INVESTIGATION
- De novo fatty acid synthesis controls the fate between regulatory T and T helper 17 cells
- (2014) Luciana Berod et al. NATURE MEDICINE
- Differential effects of AMPK agonists on cell growth and metabolism
- (2014) E E Vincent et al. ONCOGENE
- Innate and adaptive immunity in inflammatory bowel disease
- (2013) Alessandra Geremia et al. AUTOIMMUNITY REVIEWS
- Biochemical Basis of the Antidiabetic Activity of Oleanolic Acid and Related Pentacyclic Triterpenes
- (2013) J. M. Castellano et al. DIABETES
- Metabolic control of the Treg/Th17 axis
- (2013) Joseph Barbi et al. IMMUNOLOGICAL REVIEWS
- Increased Prevalence of Circulating Novel IL-17 Secreting Foxp3 Expressing CD4+ T Cells and Defective Suppressive Function of Circulating Foxp3+ Regulatory Cells Support Plasticity Between Th17 and Regulatory T Cells in Inflammatory Bowel Disease Patients
- (2013) Aito Ueno et al. INFLAMMATORY BOWEL DISEASES
- Asiatic Acid Isolated From Centella Asiatica Inhibits TGF-β1-induced Collagen Expression in Human Keloid Fibroblasts via PPAR-γ Activation
- (2013) Difei Bian et al. International Journal of Biological Sciences
- Metabolism of inflammation limited by AMPK and pseudo-starvation
- (2013) Luke A. J. O'Neill et al. NATURE
- Antigen-specific transforming growth factor β-induced Treg cells, but not natural Treg cells, ameliorate autoimmune arthritis in mice by shifting the Th17/Treg cell balance from Th17 predominance to Treg cell predominance
- (2012) Ning Kong et al. ARTHRITIS AND RHEUMATISM
- Integrated Virtual Screening for the Identification of Novel and Selective Peroxisome Proliferator-Activated Receptor (PPAR) Scaffolds
- (2012) Daniel K. Nevin et al. JOURNAL OF MEDICINAL CHEMISTRY
- Dietary abscisic acid ameliorates influenza-virus-associated disease and pulmonary immunopathology through a PPARγ-dependent mechanism
- (2012) Raquel Hontecillas et al. JOURNAL OF NUTRITIONAL BIOCHEMISTRY
- Metabolic checkpoints in activated T cells
- (2012) Ruoning Wang et al. NATURE IMMUNOLOGY
- AMPK: a nutrient and energy sensor that maintains energy homeostasis
- (2012) D. Grahame Hardie et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Amorfrutins are potent antidiabetic dietary natural products
- (2012) C. Weidner et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Nuclear receptor PPAR -regulated monoacylglycerol O-acyltransferase 1 (MGAT1) expression is responsible for the lipid accumulation in diet-induced hepatic steatosis
- (2012) Y. J. Lee et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Experimental Inflammatory Bowel Disease: Insights into the Host-Microbiota Dialog
- (2011) Maya Saleh et al. IMMUNITY
- Association of peroxisome proliferator-activated receptor gamma polymorphisms with inflammatory bowel disease in a Hungarian cohort
- (2011) Szilard Poliska et al. INFLAMMATORY BOWEL DISEASES
- Antigen-Specific TGF- -Induced Regulatory T Cells Secrete Chemokines, Regulate T Cell Trafficking, and Suppress Ongoing Autoimmunity
- (2011) T.-L. M. Nguyen et al. JOURNAL OF IMMUNOLOGY
- Intestinal homeostasis and its breakdown in inflammatory bowel disease
- (2011) Kevin J. Maloy et al. NATURE
- The nuclear orphan receptor Nr4a2 induces Foxp3 and regulates differentiation of CD4+ T cells
- (2011) Takashi Sekiya et al. Nature Communications
- Topical Rosiglitazone Treatment Improves Ulcerative Colitis by Restoring Peroxisome Proliferator-Activated Receptor-γ Activity
- (2010) Gitte Pedersen et al. AMERICAN JOURNAL OF GASTROENTEROLOGY
- PPARs: diverse regulators in energy metabolism and metabolic diseases
- (2010) Yong-Xu Wang CELL RESEARCH
- Immunoregulatory mechanisms of macrophage PPAR-γ in mice with experimental inflammatory bowel disease
- (2010) R Hontecillas et al. Mucosal Immunology
- The dual nature of TH17 cells: shifting the focus to function
- (2010) William O'Connor et al. NATURE IMMUNOLOGY
- Peroxisome proliferator-activated receptor gamma activation is required for maintenance of innate antimicrobial immunity in the colon
- (2010) L. Peyrin-Biroulet et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Development, regulation and functional capacities of Th17 cells
- (2010) Keiji Hirota et al. Seminars in Immunopathology
- Developmental plasticity of Th17 and Treg cells
- (2009) Yun Kyung Lee et al. CURRENT OPINION IN IMMUNOLOGY
- Foxp3+ Regulatory T Cells, Th17 Effector Cells, and Cytokine Environment in Inflammatory Bowel Disease
- (2009) Nicola Eastaff-Leung et al. JOURNAL OF CLINICAL IMMUNOLOGY
- Pentacyclic Triterpenoids from the Medicinal Herb, Centella asiatica (L.) Urban
- (2009) Jacinda James et al. MOLECULES
- IL-23 and Autoimmunity: New Insights into the Pathogenesis of Inflammatory Bowel Disease
- (2008) Clara Abraham et al. Annual Review of Medicine
Add your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload NowAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started