Current status of nanoscale drug delivery and the future of nano-vaccine development for leishmaniasis – A review

Understanding the immune responses involved in mediating protection or immunopathology during leishmaniasis

(2021) Thalia Pacheco-Fernandez et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Antileishmanial effect of silver nanoparticles: Green synthesis, characterization, in vivo and in vitro assessment

(2021) Manal Ahmed Awad et al.   BIOMEDICINE & PHARMACOTHERAPY

Combinatorial delivery of antigen and TLR agonists via PLGA nanoparticles modulates Leishmania major-infected-macrophages activation

(2021) Asal Katebi et al.   BIOMEDICINE & PHARMACOTHERAPY

7,8-dihydroxyflavone-functionalized gold nanoparticles target the arginase enzyme of Leishmania donovani

(2021) Pragya Prasanna et al.   Nanomedicine

Use of liposomal nanoformulations in antileishmania therapy: challenges and perspectives

(2020) Jair Téllez et al.   JOURNAL OF LIPOSOME RESEARCH

Toxicity of metal and metal oxide nanoparticles: a review

(2020) Ayse Busra Sengul et al.   Environmental Chemistry Letters

Modified solid lipid nanoparticles encapsulated with Amphotericin B and Paromomycin: an effective oral combination against experimental murine visceral leishmaniasis

(2020) Shabi Parvez et al.   Scientific Reports

Evaluation of Safety and Antileishmanial Efficacy of Amine Functionalized Carbon-Based Composite Nanoparticle Appended With Amphotericin B: An in vitro and Preclinical Study

(2020) Mallikarjuna Rao Gedda et al.   Frontiers in Chemistry

A candidate vaccine for human visceral leishmaniasis based on a specific T cell epitope-containing chimeric protein protects mice against Leishmania infantum infection

(2020) Daniela P. Lage et al.   npj Vaccines

Liposomal Formulation of ChimeraT, a Multiple T-Cell Epitope-Containing Recombinant Protein, Is a Candidate Vaccine for Human Visceral Leishmaniasis

(2020) Daniela P. Lage et al.   Vaccines

Gold–Silver Bimetallic Nanoparticles Reduced with Herbal Leaf Extracts Induce ROS-Mediated Death in Both Promastigote and Amastigote Stages of Leishmania donovani

(2020) Dayakar Alti et al.   ACS Omega

Formulation, characterization and in vitro anti-leishmanial evaluation of amphotericin B loaded solid lipid nanoparticles coated with vitamin B12-stearic acid conjugate

(2020) Aakriti Singh et al.   Materials Science & Engineering C-Materials for Biological Applications

Nanoparticle Surface Functionalization: How to Improve Biocompatibility and Cellular Internalization

(2020) Gennaro Sanità et al.   Frontiers in Molecular Biosciences

Protection induced by Leishmania Major antigens and the imiquimod adjuvant encapsulated on liposomes in experimental cutaneous leishmaniasis

(2019) Ahmad Mehravaran et al.   INFECTION GENETICS AND EVOLUTION

Alginate nanoparticles as non-toxic delivery system for miltefosine in the treatment of candidiasis and cryptococcosis

(2019) Cristina de Castro Spadari et al.   International Journal of Nanomedicine

Encapsulation of proteins from Leishmania panamensis into PLGA particles by a single emulsion-solvent evaporation method

(2019) Juan David Ospina-Villa et al.   JOURNAL OF MICROBIOLOGICAL METHODS

Envisioning the innovations in nanomedicine to combat visceral leishmaniasis: for future theranostic application

(2019) Om Prakash Singh et al.   Nanomedicine

Niosomal formulation of amphotericin B alone and in combination with glucantime: In vitro and in vivo leishmanicidal effects

(2019) Mahshid Mostafavi et al.   BIOMEDICINE & PHARMACOTHERAPY

Synthesis, characterization, and mechanistic studies of a gold nanoparticle–amphotericin B covalent conjugate with enhanced antileishmanial efficacy and reduced cytotoxicity

(2019) Prakash Kumar et al.   International Journal of Nanomedicine

Anti-Leishmanial Vaccines: Assumptions, Approaches, and Annulments

(2019) Shubhranshu Zutshi et al.   Vaccines

Unexpected intracellular biodegradation and recrystallization of gold nanoparticles

(2019) Alice Balfourier et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Applications of Nanomaterials in Leishmaniasis: A Focus on Recent Advances and Challenges

(2019) Kiran Saleem et al.   Nanomaterials

Bovine serum albumin nanoparticles containing amphotericin B were effective in treating murine cutaneous leishmaniasis and reduced the drug toxicity

(2018) D.M. Casa et al.   EXPERIMENTAL PARASITOLOGY

Cationic liposomes formulated with a novel whole Leishmania lysate (WLL) as a vaccine for leishmaniasis in murine model

(2018) Iman Jafari et al.   IMMUNOBIOLOGY

Enhancement of Th1 immune response against Leishmania cysteine peptidase A, B by PLGA nanoparticle

(2018) H. Noormehr et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Promising nanotherapy in treating leishmaniasis

(2018) Aline de Souza et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Andrographolide engineered gold nanoparticle to overcome drug resistant visceral leishmaniasis

(2018) Suvadra Das et al.   Artificial Cells Nanomedicine and Biotechnology

A Leishmania hypothetical protein-containing liposome-based formulation is highly immunogenic and induces protection against visceral leishmaniasis

(2018) Patrícia A.F. Ribeiro et al.   CYTOKINE

Comparative antileishmanial efficacy of the biosynthesised ZnO NPs from genus Verbena

(2018) Sumaira et al.   IET Nanobiotechnology

Leishmaniasis

(2018) Sakib Burza et al.   LANCET

Increased in vitro leishmanicidal activity of octyl gallate loaded poly(methyl methacrylate) nanoparticles

(2018) Paulo Emilio Feuser et al.   PHARMACEUTICAL DEVELOPMENT AND TECHNOLOGY

The impact of nanoparticle-driven lysosomal alkalinization on cellular functionality

(2018) Bella B. Manshian et al.   JOURNAL OF NANOBIOTECHNOLOGY

Surface Charge-Dependent Cellular Uptake of Polystyrene Nanoparticles

(2018) Soyeon Jeon et al.   Nanomaterials

Strategies to Obtain Encapsulation and Controlled Release of Pentamidine in Mesoporous Silica Nanoparticles

(2018) Enrico Peretti et al.   Pharmaceutics

The role of LPD-nanoparticles containing recombinant major surface glycoprotein of Leishmania (rgp63) in protection against leishmaniasis in murine model

(2017) Hengameh Firouzmand et al.   IMMUNOPHARMACOLOGY AND IMMUNOTOXICOLOGY

Nanostructured delivery systems with improved leishmanicidal activity: a critical review

(2017) Natascia Bruni et al.   International Journal of Nanomedicine

Nanoliposomal artemisinin for the treatment of murine visceral leishmaniasis

(2017) Muzamil Y. Want et al.   International Journal of Nanomedicine

Liposomal formulations in the pharmacological treatment of leishmaniasis: a review

(2017) Vanessa Ortega et al.   JOURNAL OF LIPOSOME RESEARCH

Synthesis of phytochemicals-stabilized gold nanoparticles and their biological activities against bacteria and Leishmania

(2017) Aftab Ahmad et al.   MICROBIAL PATHOGENESIS

Development of mannose-anchored thiolated amphotericin B nanocarriers for treatment of visceral leishmaniasis

(2017) Gul Shahnaz et al.   Nanomedicine

Cost-effectiveness of liposomal amphotericin B in hospitalised patients with mucocutaneous leishmaniasis

(2017) Sóstenes Mistro et al.   TROPICAL MEDICINE & INTERNATIONAL HEALTH

A Poly(Lactic-co-Glycolic) Acid Nanovaccine Based on Chimeric Peptides from Different Leishmania infantum Proteins Induces Dendritic Cells Maturation and Promotes Peptide-Specific IFNγ-Producing CD8+ T Cells Essential for the Protection against Experimental Visceral Leishmaniasis

(2017) Evita Athanasiou et al.   Frontiers in Immunology

Virus-like Particle Display of the α-Gal Carbohydrate for Vaccination against Leishmania Infection

(2017) Anna Paula V. Moura et al.   ACS Central Science

Field trial of efficacy of the Leish-tec® vaccine against canine leishmaniasis caused by Leishmania infantum in an endemic area with high transmission rates

(2017) Gabriel Grimaldi et al.   PLoS One

Coadminstration of L. major amastigote class I nuclease (rLmaCIN) with LPD nanoparticles delays the progression of skin lesion and the L. major dissemination to the spleen in BALB/c mice-based experimental setting

(2016) Fatemeh Fakhraee et al.   ACTA TROPICA

Nanotized Curcumin and Miltefosine, a Potential Combination for Treatment of Experimental Visceral Leishmaniasis

(2016) Brajendra Tiwari et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Solid lipid nanoparticle loaded with paromomycin: in vivo efficacy against Leishmania tropica infection in BALB/c mice model

(2016) Maryam Heidari-Kharaji et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Liposomal Amphotericin B (AmBisome®): A Review of the Pharmacokinetics, Pharmacodynamics, Clinical Experience and Future Directions

(2016) Neil R. H. Stone et al.   DRUGS

The biological activity of cationic liposomes in drug delivery and toxicity test in animal models

(2016) Panpan Qi et al.   ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY

Biocompatible silver nanoparticles reduced from Anethum graveolens leaf extract augments the antileishmanial efficacy of miltefosine

(2016) Suresh K. Kalangi et al.   EXPERIMENTAL PARASITOLOGY

Oleanolic acid loaded poly lactic co- glycolic acid- vitamin E TPGS nanoparticles for the treatment of Leishmania donovani infected visceral leishmaniasis

(2016) Santanu Ghosh et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Annihilation of Leishmania by daylight responsive ZnO nanoparticles: a temporal relationship of reactive oxygen species-induced lipid and protein oxidation

(2016) Akhtar Nadhman et al.   International Journal of Nanomedicine

Isatis tinctoria mediated synthesis of amphotericin B-bound silver nanoparticles with enhanced photoinduced antileishmanial activity: A novel green approach

(2016) Aftab Ahmad et al.   JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY

Reverse Size Dependences of the Cellular Uptake of Triangular and Spherical Gold Nanoparticles

(2016) Katsuyuki Nambara et al.   LANGMUIR

Development of PLGA–PEG encapsulated miltefosine based drug delivery system against visceral leishmaniasis

(2016) Rishikesh Kumar et al.   Materials Science & Engineering C-Materials for Biological Applications

Status of vaccine research and development of vaccines for leishmaniasis

(2016) Portia M. Gillespie et al.   VACCINE

An effective in vitro and in vivo antileishmanial activity and mechanism of action of 8-hydroxyquinoline against Leishmania species causing visceral and tegumentary leishmaniasis

(2016) Mariana Costa Duarte et al.   VETERINARY PARASITOLOGY

Investigational nanomedicines in 2016: a review of nanotherapeutics currently undergoing clinical trials

(2016) Joseph M. Caster et al.   Wiley Interdisciplinary Reviews-Nanomedicine and Nanobiotechnology

Cationic Solid Lipid Nanoparticles Loaded by Cystein Proteinase Genes as a Novel anti-Leishmaniasis DNA Vaccine Delivery System: Characterization and in vitro Evaluations

(2016) Delaram Doroud et al.   JOURNAL OF PHARMACY AND PHARMACEUTICAL SCIENCES

The Interplay of Size and Surface Functionality on the Cellular Uptake of Sub-10 nm Gold Nanoparticles

(2015) Ying Jiang et al.   ACS Nano

Green Synthesis of Silver and Titanium Dioxide Nanoparticles Using Euphorbia prostrata Extract Shows Shift from Apoptosis to G0/G1Arrest followed by Necrotic Cell Death in Leishmania donovani

(2015) Abdul Abduz Zahir et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Therapeutic and immunomodulatory activities of short-course treatment of murine visceral leishmaniasis with KALSOME™10, a new liposomal amphotericin B

(2015) Mohammad Asad et al.   BMC INFECTIOUS DISEASES

Treatment of Disseminated Leishmaniasis With Liposomal Amphotericin B

(2015) Paulo R. L. Machado et al.   CLINICAL INFECTIOUS DISEASES

Therapeutic efficacy of artemisinin-loaded nanoparticles in experimental visceral leishmaniasis

(2015) Muzamil Yaqub Want et al.   COLLOIDS AND SURFACES B-BIOINTERFACES

Th-1 biased immunomodulation and synergistic antileishmanial activity of stable cationic lipid–polymer hybrid nanoparticle: Biodistribution and toxicity assessment of encapsulated amphotericin B

(2015) Shalini Asthana et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

Studies on the protective efficacy of freeze thawed promastigote antigen of Leishmania donovani along with various adjuvants against visceral leishmaniasis infection in mice

(2015) Ankita Thakur et al.   IMMUNOBIOLOGY

Chondroitin nanocapsules enhanced doxorubicin induced apoptosis against leishmaniasis via Th1 immune response

(2015) Mohini Chaurasia et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Phytosynthesis and Antileishmanial Activity of Gold Nanoparticles byMaytenus Royleanus

(2015) Aftab Ahmad et al.   JOURNAL OF FOOD BIOCHEMISTRY

Surface functionalization of polymeric nanospheres modulates macrophage activation: relevance in Leishmaniasis therapy

(2015) Daniela Barros et al.   Nanomedicine

Targeted chemotherapy of visceral leishmaniasis by lactoferrin-appended amphotericin B-loaded nanoreservoir: in vitro and in vivo studies.

(2015) Shalini Asthana et al.   Nanomedicine

Principles of nanoparticle design for overcoming biological barriers to drug delivery

(2015) Elvin Blanco et al.   NATURE BIOTECHNOLOGY

Proteomics analysis of the mode of antibacterial action of nanoparticles and their interactions with proteins

(2015) Hani Nasser Abdelhamid et al.   TRAC-TRENDS IN ANALYTICAL CHEMISTRY

Chitosan-based mucosal adjuvants: Sunrise on the ocean

(2015) Yufei Xia et al.   VACCINE

Cationic Liposomal Sodium Stibogluconate (SSG), a Potent Therapeutic Tool for Treatment of Infection by SSG-Sensitive and -Resistant Leishmania donovani

(2014) Roma Sinha et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Chitosan-Assisted Immunotherapy for Intervention of Experimental Leishmaniasis via Amphotericin B-Loaded Solid Lipid Nanoparticles

(2014) Vineet Jain et al.   APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY

Exploitation of Lectinized Lipo-Polymerosome Encapsulated Amphotericin B to Target Macrophages for Effective Chemotherapy of Visceral Leishmaniasis

(2014) Pramod K. Gupta et al.   BIOCONJUGATE CHEMISTRY

Dextran derivative-based pH-sensitive liposomes for cancer immunotherapy

(2014) Eiji Yuba et al.   BIOMATERIALS

The curative effect of fucoidan on visceral leishmaniasis is mediated by activation of MAP kinases through specific protein kinase C isoforms

(2014) Gunjan Sharma et al.   Cellular & Molecular Immunology

Study the effects of PLGA-PEG encapsulated Amphotericin B nanoparticle drug delivery system against Leishmania donovani

(2014) Rishikesh Kumar et al.   DRUG DELIVERY

Particle-specific toxic effects of differently shaped zinc oxide nanoparticles to zebrafish embryos (Danio rerio )

(2014) Jing Hua et al.   ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY

Anti-leishmanial effect of itraconazole niosome on in vitro susceptibility of Leishmania tropica

(2014) Payam Khazaeli et al.   ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY

Immunoliposomes containing Soluble Leishmania Antigens (SLA) as a novel antigen delivery system in murine model of leishmaniasis

(2014) Faeze Eskandari et al.   EXPERIMENTAL PARASITOLOGY

Use of topical liposomes containing meglumine antimoniate (Glucantime) for the treatment of L. major lesion in BALB/c mice

(2014) S.A. Moosavian Kalat et al.   EXPERIMENTAL PARASITOLOGY

Development of targeted 1,2-diacyl-sn-glycero-3-phospho-l-serine-coated gelatin nanoparticles loaded with amphotericin B for improvedin vitroandin vivoeffect in leishmaniasis

(2014) Renuka Khatik et al.   Expert Opinion on Drug Delivery

Mixed formulation of conventional and pegylated liposomes as a novel drug delivery strategy for improved treatment of visceral leishmaniasis

(2014) Erly G Azevedo et al.   Expert Opinion on Drug Delivery

Targeting human dendritic cells in situ to improve vaccines

(2014) Kartik Sehgal et al.   IMMUNOLOGY LETTERS

Leishmania donovani activates SREBP2 to modulate macrophage membrane cholesterol and mitochondrial oxidants for establishment of infection

(2014) Madhuchhanda Mukherjee et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

A new approach for the delivery of artemisinin: Formulation, characterization, and ex-vivo antileishmanial studies

(2014) Muzamil Yaqub Want et al.   JOURNAL OF COLLOID AND INTERFACE SCIENCE

Advances in lipid-based colloid systems as drug carrier for topic delivery

(2014) Yingjie Zhai et al.   JOURNAL OF CONTROLLED RELEASE

Covalent Functionalized Self-Assembled Lipo-Polymerosome Bearing Amphotericin B for Better Management of Leishmaniasis and Its Toxicity Evaluation

(2014) Pramod K. Gupta et al.   MOLECULAR PHARMACEUTICS

Crucial CD8+ T-lymphocyte cytotoxic role in amphotericin B nanospheres efficacy against experimental visceral leishmaniasis

(2014) Sofia A. Costa Lima et al.   Nanomedicine-Nanotechnology Biology and Medicine

Carbon nanotube based betulin formulation shows better efficacy against Leishmania parasite

(2014) Prakash Saudagar et al.   PARASITOLOGY INTERNATIONAL

Self Assembled Ionically Sodium Alginate Cross-Linked Amphotericin B Encapsulated Glycol Chitosan Stearate Nanoparticles: Applicability in Better Chemotherapy and Non-Toxic Delivery in Visceral Leishmaniasis

(2014) Pramod K. Gupta et al.   PHARMACEUTICAL RESEARCH

Nanoparticles as drug delivery systems

(2014) Agnieszka Z. Wilczewska et al.   Pharmacological Reports

Toxicity of Metal Oxide Nanoparticles: Mechanisms, Characterization, and Avoiding Experimental Artefacts

(2014) Aleksandra B. Djurišić et al.   Small

Nanodelivery of Bioactive Components for Food Applications: Types of Delivery Systems, Properties, and Their Effect on ADME Profiles and Toxicity of Nanoparticles

(2014) T. Borel et al.   Annual Review of Food Science and Technology

Antileishmanial Activity, Uptake, and Biodistribution of an Amphotericin B and Poly(α-Glutamic Acid) Complex

(2013) Abeer H. A. Mohamed-Ahmed et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Mannose-conjugated chitosan nanoparticles loaded with rifampicin for the treatment of visceral leishmaniasis

(2013) Pramila Chaubey et al.   CARBOHYDRATE POLYMERS

One pot synthesis of gold nanoparticles and application in chemotherapy of wild and resistant type visceral leishmaniasis

(2013) Suvadra Das et al.   COLLOIDS AND SURFACES B-BIOINTERFACES

Leishmanicidal activity of amphotericin B encapsulated in PLGA–DMSA nanoparticles to treat cutaneous leishmaniasis in C57BL/6 mice

(2013) Ricardo Fontoura de Carvalho et al.   EXPERIMENTAL PARASITOLOGY

Drug resistance in leishmaniasis: current drug-delivery systems and future perspectives

(2013) Masoom Yasinzai et al.   Future Medicinal Chemistry

Liposomal Cholesterol Delivery Activates the Macrophage Innate Immune Arm To Facilitate Intracellular Leishmania donovani Killing

(2013) June Ghosh et al.   INFECTION AND IMMUNITY

Development of liposomes loaded with anti-leishmanial drugs for the treatment of cutaneous leishmaniasis

(2013) Arash Momeni et al.   JOURNAL OF LIPOSOME RESEARCH

Development of doxorubicin loaded novel core shell structured nanocapsules for the intervention of visceral leishmaniasis

(2013) Shaswat Kansal et al.   JOURNAL OF MICROENCAPSULATION

Electrospray Encapsulation of Toll-Like Receptor Agonist Resiquimod in Polymer Microparticles for the Treatment of Visceral Leishmaniasis

(2013) Anthony D. Duong et al.   MOLECULAR PHARMACEUTICS

Cationic solid-lipid nanoparticles are as efficient as electroporation in DNA vaccination against visceral leishmaniasis in mice

(2013) N. Saljoughian et al.   PARASITE IMMUNOLOGY

In Vitro Susceptibilities of Wild and Drug Resistant Leishmania donovani Amastigote Stages to Andrographolide Nanoparticle: Role of Vitamin E Derivative TPGS for Nanoparticle Efficacy

(2013) Subhasish Mondal et al.   PLoS One

Liposome: classification, preparation, and applications

(2013) Abolfazl Akbarzadeh et al.   Nanoscale Research Letters

Surface Defects on Plate-Shaped Silver Nanoparticles Contribute to Its Hazard Potential in a Fish Gill Cell Line and Zebrafish Embryos

(2012) Saji George et al.   ACS Nano

Enhanced leishmanicidal activity of cryptopeptide chimeras from the active N1 domain of bovine lactoferrin

(2012) Tânia Silva et al.   AMINO ACIDS

A review of glycosylated carriers for drug delivery

(2012) Keerti Jain et al.   BIOMATERIALS

Vitamin E TPGS as a molecular biomaterial for drug delivery

(2012) Zhiping Zhang et al.   BIOMATERIALS

Discovery of a new antileishmanial hit in 8-nitroquinoline series

(2012) Lucie Paloque et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Mitochondrial damage contribute to epigallocatechin-3-gallate induced death in Leishmania amazonensis

(2012) Job D.F. Inacio et al.   EXPERIMENTAL PARASITOLOGY

Modes of action of Leishmanicidal antimicrobial peptides

(2012) Alexandra K Marr et al.   Future Microbiology

115kDa serine protease confers sustained protection to visceral leishmaniasis caused by Leishmania donovani via IFN-γ induced down-regulation of TNF-α mediated MMP-9 activity

(2012) Rajdeep Choudhury et al.   IMMUNOBIOLOGY

The role of surface charge in cellular uptake and cytotoxicity of medical nanoparticles

(2012) Eleonore Fröhlich   International Journal of Nanomedicine

Development of nanocapsules bearing doxorubicin for macrophage targeting through the phosphatidylserine ligand: a system for intervention in visceral leishmaniasis

(2012) S. Kansal et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Efficacy and tolerability of oleylphosphocholine (OlPC) in a laboratory model of visceral leishmaniasis

(2012) A. Fortin et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Evaluating the Potential of Polyester Nanoparticles for Per Oral Delivery of Amphotericin B in Treating Visceral Leishmaniasis

(2012) J. L. Italia et al.   Journal of Biomedical Nanotechnology

The efficacy of aerosol treatment with non-ionic surfactant vesicles containing amphotericin B in rodent models of leishmaniasis and pulmonary aspergillosis infection

(2012) M. Alsaadi et al.   JOURNAL OF CONTROLLED RELEASE

PLGA nanoparticles and nanosuspensions with amphotericin B: Potent in vitro and in vivo alternatives to Fungizone and AmBisome

(2012) H. Van de Ven et al.   JOURNAL OF CONTROLLED RELEASE

Biosynthesis of stabilised gold nanoparticle using an aglycone flavonoid, quercetin

(2012) Dipesh Kr. Das et al.   Journal of Experimental Nanoscience

Characterization and evaluation of BNIPDaoct-loaded PLGA nanoparticles for visceral leishmaniasis:in vitroandin vivostudies

(2012) Sofia A Costa Lima et al.   Nanomedicine

Cationic liposomes containing soluble Leishmania antigens (SLA) plus CpG ODNs induce protection against murine model of leishmaniasis

(2012) Vahid Heravi Shargh et al.   PARASITOLOGY RESEARCH

Leishmaniasis Worldwide and Global Estimates of Its Incidence

(2012) Jorge Alvar et al.   PLoS One

Immunogenicity and immune modulatory effects of in silico predictedL. donovanicandidate peptide vaccines

(2012) Mona E.E. Elfaki et al.   Human Vaccines & Immunotherapeutics

Paromomycin loaded solid lipid nanoparticles: Characterization of production parameters

(2011) Maryam Ghadiri et al.   BIOTECHNOLOGY AND BIOPROCESS ENGINEERING

Leishmaniasis: focus on the design of nanoparticulate vaccine delivery systems

(2011) Delaram Doroud et al.   Expert Review of Vaccines

Antileishmanial effect of silver nanoparticles and their enhanced antiparasitic activity under ultraviolet light

(2011) Adil Allahverdiyev et al.   International Journal of Nanomedicine

Targeted killing of Leishmania donovani in vivo and in vitro with amphotericin B attached to functionalized carbon nanotubes

(2011) V. K. Prajapati et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

An Oral Formulation of Amphotericin B Attached to Functionalized Carbon Nanotubes Is an Effective Treatment for Experimental Visceral Leishmaniasis

(2011) Vijay Kumar Prajapati et al.   JOURNAL OF INFECTIOUS DISEASES

Chitosan-based macrophage-mediated drug targeting for the treatment of experimental visceral leishmaniasis

(2011) Sijumon Kunjachan et al.   JOURNAL OF MICROENCAPSULATION

Preparation and evaluation of niosomes containing autoclavedLeishmania major: a preliminary study

(2011) Abbas Pardakhty et al.   JOURNAL OF MICROENCAPSULATION

Comparison of short-course multidrug treatment with standard therapy for visceral leishmaniasis in India: an open-label, non-inferiority, randomised controlled trial

(2011) Shyam Sundar et al.   LANCET

Vaccination with Liposomal Leishmanial Antigens Adjuvanted with Monophosphoryl Lipid–Trehalose Dicorynomycolate (MPL-TDM) Confers Long-Term Protection against Visceral Leishmaniasis through a Human Administrable Route

(2011) Rajesh Ravindran et al.   MOLECULAR PHARMACEUTICS

Therapy with Sodium Stibogluconate in Stearylamine-Bearing Liposomes Confers Cure against SSG-Resistant Leishmania donovani in BALB/c Mice

(2011) Jayeeta Roychoudhury et al.   PLoS One

Cellular vaccination with bone marrow-derived dendritic cells pulsed with a peptide of Leishmania infantum KMP-11 and CpG oligonucleotides induces protection in a murine model of visceral leishmaniasis

(2011) Maria Agallou et al.   VACCINE

The development and clinical evaluation of second-generation leishmaniasis vaccines

(2011) Malcolm S. Duthie et al.   VACCINE

Adjuvants and delivery systems in veterinary vaccinology: current state and future developments

(2010) Peter M. H. Heegaard et al.   ARCHIVES OF VIROLOGY

Polymeric particles in vaccine delivery

(2010) Allison C Rice-Ficht et al.   CURRENT OPINION IN MICROBIOLOGY

Geometry and surface characteristics of gold nanoparticles influence their biodistribution and uptake by macrophages

(2010) Arnida et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

New delivery strategies for the old pentavalent antimonial drugs

(2010) Frédéric Frézard et al.   Expert Opinion on Drug Delivery

Advances in the design and delivery of peptide subunit vaccines with a focus on Toll-like receptor agonists

(2010) Matthew Black et al.   Expert Review of Vaccines

In vitroevaluation of surface functionalized gelatin nanoparticles for macrophage targeting in the therapy of visceral leishmaniasis

(2010) Manoj Nahar et al.   JOURNAL OF DRUG TARGETING

Leishmania Exosomes Modulate Innate and Adaptive Immune Responses through Effects on Monocytes and Dendritic Cells

(2010) J. M. Silverman et al.   JOURNAL OF IMMUNOLOGY

Inhibitory Effect of Silver Nanoparticles on Trypanothione Reductase Activity and Leishmania infantum Proliferation

(2010) Paola Baiocco et al.   ACS Medicinal Chemistry Letters

Nanoparticle interaction with plasma proteins as it relates to particle biodistribution, biocompatibility and therapeutic efficacy

(2009) Parag Aggarwal et al.   ADVANCED DRUG DELIVERY REVIEWS

The role of liposome charge on immune response generated in BALB/c mice immunized with recombinant major surface glycoprotein of Leishmania (rgp63)

(2009) Ali Badiee et al.   EXPERIMENTAL PARASITOLOGY

Assessment of the In Vivo Toxicity of Gold Nanoparticles

(2009) Yu-Shiun Chen et al.   Nanoscale Research Letters

Preparation, Characterization and Evaluation of Targeting Potential of Amphotericin B-Loaded Engineered PLGA Nanoparticles

(2009) Manoj Nahar et al.   PHARMACEUTICAL RESEARCH

Biodegradable Nanoparticles Improve Oral Bioavailability of Amphotericin B and Show Reduced Nephrotoxicity Compared to Intravenous Fungizone®

(2009) J. L. Italia et al.   PHARMACEUTICAL RESEARCH

Polysaccharides-based nanoparticles as drug delivery systems

(2008) Zonghua Liu et al.   ADVANCED DRUG DELIVERY REVIEWS

Antimony Resistance and Trypanothione in Experimentally Selected and Clinical Strains of Leishmania panamensis

(2008) D. A. Goyeneche-Patino et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

gp63 in Stable Cationic Liposomes Confers Sustained Vaccine Immunity to Susceptible BALB/c Mice Infected with Leishmania donovani

(2008) S. Bhowmick et al.   INFECTION AND IMMUNITY

N-(2-hydroxypropyl)methacrylamide–amphotericin B (HPMA–AmB) copolymer conjugates as antileishmanial agents

(2008) Salvatore Nicoletti et al.   INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS

Immunomodulatory biomaterials

(2008) Surya K. Mallapragada et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS