A Poly(Lactic-co-Glycolic) Acid Nanovaccine Based on Chimeric Peptides from Different Leishmania infantum Proteins Induces Dendritic Cells Maturation and Promotes Peptide-Specific IFNγ-Producing CD8+ T Cells Essential for the Protection against Experimental Visceral Leishmaniasis

Distinct Antigen Delivery Systems Induce Dendritic Cells’ Divergent Transcriptional Response: New Insights from a Comparative and Reproducible Computational Analysis

(2017) Valerio Costa et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Identification of BALB/c Immune Markers Correlated with a Partial Protection to Leishmania infantum after Vaccination with a Rationally Designed Multi-epitope Cysteine Protease A Peptide-Based Nanovaccine

(2017) Maria Agallou et al.   PLoS Neglected Tropical Diseases

A Chimera Containing CD4+ and CD8+ T-Cell Epitopes of the Leishmania donovani Nucleoside Hydrolase (NH36) Optimizes Cross-Protection against Leishmania amazonesis Infection

(2017) Marcus Vinícius Alves-Silva et al.   Frontiers in Immunology

PLGA nanoparticles modified with a TNFα mimicking peptide, soluble Leishmania antigens and MPLA induce T cell priming in vitro via dendritic cell functional differentiation

(2016) Maritsa Margaroni et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

Synthetic long peptide-based vaccine formulations for induction of cell mediated immunity: A comparative study of cationic liposomes and PLGA nanoparticles

(2016) Eleni Maria Varypataki et al.   JOURNAL OF CONTROLLED RELEASE

Enhanced stimulation of anti-breast cancer T cells responses by dendritic cells loaded with poly lactic-co-glycolic acid (PLGA) nanoparticle encapsulated tumor antigens

(2016) Soodabeh Iranpour et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Regulation of immunity during visceral Leishmania infection

(2016) Vasco Rodrigues et al.   Parasites & Vectors

Study of Leishmania pathogenesis in mice: experimental considerations

(2016) Corinne Loeuillet et al.   Parasites & Vectors

Designing string-of-beads vaccines with optimal spacers

(2016) Benjamin Schubert et al.   Genome Medicine

PLGA particulate delivery systems for subunit vaccines: Linking particle properties to immunogenicity

(2016) A. L. Silva et al.   Human Vaccines & Immunotherapeutics

Post-Genomics and Vaccine Improvement for Leishmania

(2016) Negar Seyed et al.   Frontiers in Microbiology

The Notch Ligand DLL4 Defines a Capability of Human Dendritic Cells in Regulating Th1 and Th17 Differentiation

(2015) Lijun Meng et al.   JOURNAL OF IMMUNOLOGY

Improving Multi-Epitope Long Peptide Vaccine Potency by Using a Strategy that Enhances CD4+ T Help in BALB/c Mice

(2015) Haniyeh Ghaffari-Nazari et al.   PLoS One

Innate Responses Induced by Whole Inactivated Virus or Subunit Influenza Vaccines in Cultured Dendritic Cells Correlate with Immune Responses In Vivo

(2015) Maaike Stoel et al.   PLoS One

Molecular signatures for vaccine development

(2015) J. Maertzdorf et al.   VACCINE

Design, Immune Responses and Anti-Tumor Potential of an HPV16 E6E7 Multi-Epitope Vaccine

(2015) Liliane Maria Fernandes de Oliveira et al.   PLoS One

A novel multi-epitope peptide vaccine against cancer: An in silico approach

(2014) Navid Nezafat et al.   JOURNAL OF THEORETICAL BIOLOGY

Gene Ontology Consortium: going forward

(2014)   NUCLEIC ACIDS RESEARCH

Molecular Characterization of Antigen-Peptide Pulsed Dendritic Cells: Immature Dendritic Cells Develop a Distinct Molecular Profile when Pulsed with Antigen Peptide

(2014) Amy X. Yang et al.   PLoS One

Using Humans to Make a Human Leishmaniasis Vaccine

(2014) S. Kamhawi et al.   Science Translational Medicine

A human dendritic cell-based in vitro model to assess Mycobacterium tuberculosis SO2 vaccine immunogenicity

(2014) Marilena Etna   ALTEX-Alternatives to Animal Experimentation

Transcriptional specialization of human dendritic cell subsets in response to microbial vaccines

(2014) Romain Banchereau et al.   Nature Communications

Experimental Validation of Multi-Epitope Peptides Including Promising MHC Class I- and II-Restricted Epitopes of Four Known Leishmania infantum Proteins

(2014) Maria Agallou et al.   Frontiers in Immunology

Epidemiology of visceral leishmaniasis

(2014) Paul Ready   Clinical Epidemiology

Pathview: an R/Bioconductor package for pathway-based data integration and visualization

(2013) Weijun Luo et al.   BIOINFORMATICS

Genetic diversity and structure in Leishmania infantum populations from southeastern Europe revealed by microsatellite analysis

(2013) Evi Gouzelou et al.   Parasites & Vectors

T-cell epitope vaccine design by immunoinformatics

(2013) A. Patronov et al.   Open Biology

IL-36 signaling amplifies Th1 responses by enhancing proliferation and Th1 polarization of naive CD4+ T cells

(2012) S. Vigne et al.   BLOOD

The RIG-I-like Receptor LGP2 Controls CD8+ T Cell Survival and Fitness

(2012) Mehul S. Suthar et al.   IMMUNITY

Structural and functional distinctiveness of HLA-A2 allelic variants

(2012) Kenneth Yuanxiang Chen et al.   IMMUNOLOGIC RESEARCH

Towards development of novel immunization strategies against leishmaniasis using PLGA nanoparticles loaded with kinetoplastid membrane protein-11

(2012) Camila I. de Oliveira et al.   International Journal of Nanomedicine

Targeting tumor antigens to dendritic cells using particulate carriers

(2012) Medha D. Joshi et al.   JOURNAL OF CONTROLLED RELEASE

PLGA-based nanoparticles: An overview of biomedical applications

(2012) Fabienne Danhier et al.   JOURNAL OF CONTROLLED RELEASE

Characterization and evaluation of BNIPDaoct-loaded PLGA nanoparticles for visceral leishmaniasis:in vitroandin vivostudies

(2012) Sofia A Costa Lima et al.   Nanomedicine

clusterProfiler: an R Package for Comparing Biological Themes Among Gene Clusters

(2012) Guangchuang Yu et al.   OMICS-A JOURNAL OF INTEGRATIVE BIOLOGY

Leishmaniasis Worldwide and Global Estimates of Its Incidence

(2012) Jorge Alvar et al.   PLoS One

Immunogenicity and immune modulatory effects of in silico predictedL. donovanicandidate peptide vaccines

(2012) Mona E.E. Elfaki et al.   Human Vaccines & Immunotherapeutics

CD8+ T Cells in Leishmania Infections: Friends or Foes?

(2012) Simona Stäger et al.   Frontiers in Immunology

Targeting dendritic cells with nano-particulate PLGA cancer vaccine formulations

(2011) Samar Hamdy et al.   ADVANCED DRUG DELIVERY REVIEWS

CISH is induced during DC development and regulates DC-mediated CTL activation

(2011) Mohammad Alam Miah et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Induction of anti-tumor immunity and T-cell responses using nanodelivery systems engrafting TLR-5 ligand

(2011) Amulya K Panda   Expert Review of Vaccines

In silico identification of novel protective VSG antigens expressed by Trypanosoma brucei and an effort for designing a highly immunogenic DNA vaccine using IL-12 as adjuvant

(2011) Bashir Akhlaq Akhoon et al.   MICROBIAL PATHOGENESIS

Leishmaniasis: complexity at the host–pathogen interface

(2011) Paul Kaye et al.   NATURE REVIEWS MICROBIOLOGY

Cellular vaccination with bone marrow-derived dendritic cells pulsed with a peptide of Leishmania infantum KMP-11 and CpG oligonucleotides induces protection in a murine model of visceral leishmaniasis

(2011) Maria Agallou et al.   VACCINE

In Silico Analysis of Six Known Leishmania major Antigens and In Vitro Evaluation of Specific Epitopes Eliciting HLA-A2 Restricted CD8 T Cell Response

(2011) Negar Seyed et al.   PLoS Neglected Tropical Diseases

Oncostatin M induces dendritic cell maturation and Th1 polarization

(2010) In Duk Jung et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Advances in the design and delivery of peptide subunit vaccines with a focus on Toll-like receptor agonists

(2010) Matthew Black et al.   Expert Review of Vaccines

Essential Role of Endogenous Heat Shock Protein 90 of Dendritic Cells in Antigen Cross-Presentation

(2010) T. Ichiyanagi et al.   JOURNAL OF IMMUNOLOGY

Immunization against leishmaniasis by PLGA nanospheres encapsulated with autoclaved Leishmania major (ALM) and CpG-ODN

(2010) Mohsen Tafaghodi et al.   PARASITOLOGY RESEARCH

Antigen delivery to dendritic cells by poly(propylene sulfide) nanoparticles with disulfide conjugated peptides: Cross-presentation and T cell activation

(2010) Sachiko Hirosue et al.   VACCINE

A Role for Lipid Bodies in the Cross-presentation of Phagocytosed Antigens by MHC Class I in Dendritic Cells

(2009) Laurence Bougnères et al.   IMMUNITY

Heat-shock protein 90 associates with N-terminal extended peptides and is required for direct and indirect antigen presentation

(2008) M. K. Callahan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Immunization strategies against visceral leishmaniosis with the nucleosomal histones of Leishmania infantum encoded in DNA vaccine or pulsed in dendritic cells

(2008) Javier Carrión et al.   VACCINE

Epitope mapping and protective immunity elicited by adenovirus expressing the Leishmania amastigote specific A2 antigen: Correlation with IFN-γ and cytolytic activity by CD8+ T cells

(2008) Daniela M. Resende et al.   VACCINE

Vaccines for leishmaniasis in the fore coming 25 years

(2008) Clarisa B. Palatnik-de-Sousa   VACCINE