The impact of nanoparticle-driven lysosomal alkalinization on cellular functionality

Multiparametric analysis of anti-proliferative and apoptotic effects of gold nanoprisms on mouse and human primary and transformed cells, biodistribution and toxicity in vivo

(2017) Marta Pérez-Hernández et al.   Particle and Fibre Toxicology

Basic Physicochemical Properties of Polyethylene Glycol Coated Gold Nanoparticles that Determine Their Interaction with Cells

(2016) Pablo del Pino et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Nano-TiO2 induces autophagy to protect against cell death through antioxidative mechanism in podocytes

(2016) Xiaochen Zhang et al.   CELL BIOLOGY AND TOXICOLOGY

A potential role of X-linked inhibitor of apoptosis protein in mitochondrial membrane permeabilization and its implication in cancer therapy

(2016) Ajay K. Chaudhary et al.   DRUG DISCOVERY TODAY

Safety assessment of nanoparticles for drug delivery by means of classicin vitroassays and beyond

(2016) Stefan Lorscheidt et al.   Expert Opinion on Drug Delivery

Airborne nanoparticles (PM0.1) induce autophagic cell death of human neuronal cells

(2016) Yu-Mi Jeon et al.   JOURNAL OF APPLIED TOXICOLOGY

Proteomic approach to nanotoxicity

(2016) Magdalena Matysiak et al.   Journal of Proteomics

Silibinin negatively contributes to primary cilia length via autophagy regulated by histone deacetylase 6 in confluent mouse embryo fibroblast 3T3-L1 cells

(2016) Qian Xu et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Iron Oxide Nanoparticles Induce Autophagosome Accumulation through Multiple Mechanisms: Lysosome Impairment, Mitochondrial Damage, and ER Stress

(2016) Xudong Zhang et al.   MOLECULAR PHARMACEUTICS

An early developmental vertebrate model for nanomaterial safety: bridging cell-based and mammalian toxicity assessment

(2016) Carl A Webster et al.   Nanomedicine

Low-dose, subchronic exposure to silver nanoparticles causes mitochondrial alterations in Sprague–Dawley rats

(2016) João Soeiro Teodoro et al.   Nanomedicine

Mechanisms of silver nanoparticle-induced toxicity and important role of autophagy

(2016) Bin-Hsu Mao et al.   Nanotoxicology

Integrative functional transcriptomic analyses implicate specific molecular pathways in pulmonary toxicity from exposure to aluminum oxide nanoparticles

(2016) Xiaobo Li et al.   Nanotoxicology

Meta-analysis of cellular toxicity for cadmium-containing quantum dots

(2016) Eunkeu Oh et al.   Nature Nanotechnology

Silica nanoparticle-generated ROS as a predictor of cellular toxicity: mechanistic insights and safety by design

(2016) Sean E. Lehman et al.   Environmental Science-Nano

Hypoxia-mediated autophagic flux inhibits silver nanoparticle-triggered apoptosis in human lung cancer cells

(2016) Jae-Kyo Jeong et al.   Scientific Reports

Reduction of Acute Inflammatory Effects of Fumed Silica Nanoparticles in the Lung by Adjusting Silanol Display through Calcination and Metal Doping

(2015) Bingbing Sun et al.   ACS Nano

High-Content Imaging and Gene Expression Approaches To Unravel the Effect of Surface Functionality on Cellular Interactions of Silver Nanoparticles

(2015) Bella B. Manshian et al.   ACS Nano

(Intra)Cellular Stability of Inorganic Nanoparticles: Effects on Cytotoxicity, Particle Functionality, and Biomedical Applications

(2015) Stefaan J. Soenen et al.   CHEMICAL REVIEWS

Nanoparticle uptake: The phagocyte problem

(2015) Heather Herd Gustafson et al.   Nano Today

High content analysis at single cell level identifies different cellular responses dependent on nanomaterial concentrations

(2015) Bella B. Manshian et al.   Scientific Reports

Interplay of Oxidative Stress and Autophagy in PAMAM Dendrimers-Induced Neuronal Cell Death

(2015) Yubin Li et al.   Theranostics

The oxidative potential of differently charged silver and gold nanoparticles on three human lung epithelial cell types

(2015) Paul Schlinkert et al.   JOURNAL OF NANOBIOTECHNOLOGY

Toxicity of 12 metal-based nanoparticles to algae, bacteria and protozoa

(2015) Villem Aruoja et al.   Environmental Science-Nano

Nanoparticles modulate autophagic effect in a dispersity-dependent manner

(2015) Dengtong Huang et al.   Scientific Reports

Mesenchymal stem cells from osteoporotic patients reveal reduced migration and invasion upon stimulation with BMP-2 or BMP-7

(2014) Florian Haasters et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

High-content imaging and gene expression analysis to study cell–nanomaterial interactions: The effect of surface hydrophobicity

(2014) Bella B. Manshian et al.   BIOMATERIALS

The influence of lysosomal stability of silver nanomaterials on their toxicity to human cells

(2014) Magdiel Inggrid Setyawati et al.   BIOMATERIALS

Exploiting Intrinsic Nanoparticle Toxicity: The Pros and Cons of Nanoparticle-Induced Autophagy in Biomedical Research

(2014) Karen Peynshaert et al.   CHEMICAL REVIEWS

PdO Doping Tunes Band-Gap Energy Levels as Well as Oxidative Stress Responses to a Co3O4 p-Type Semiconductor in Cells and the Lung

(2014) Haiyuan Zhang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Dose-Response of Superparamagnetic Iron Oxide Labeling on Mesenchymal Stem Cells Chondrogenic Differentiation: A Multi-Scale In Vitro Study

(2014) Emilie Roeder et al.   PLoS One

Fluorescent non-porous silica nanoparticles for long-term cell monitoring: Cytotoxicity and particle functionality

(2013) Stefaan J. Soenen et al.   Acta Biomaterialia

Tubulin, actin and heterotrimeric G proteins: Coordination of signaling and structure

(2013) Jeffrey M. Schappi et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Cadmium-Based Quantum Dot Induced Autophagy Formation for Cell Survival via Oxidative Stress

(2013) Yueh-Hsia Luo et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Glucose-starved Cells Do Not Engage in Prosurvival Autophagy

(2013) Silvia Ramírez-Peinado et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Gold nanoparticle aerosols for rodent inhalation and translocation studies

(2013) Winfried Möller et al.   JOURNAL OF NANOPARTICLE RESEARCH

Nanoparticles Strengthen Intracellular Tension and Retard Cellular Migration

(2013) Chor Yong Tay et al.   NANO LETTERS

Custom-Designed Nanomaterial Libraries for Testing Metal Oxide Toxicity

(2012) Suman Pokhrel et al.   ACCOUNTS OF CHEMICAL RESEARCH

Cytotoxic Effects of Gold Nanoparticles: A Multiparametric Study

(2012) Stefaan J. Soenen et al.   ACS Nano

Dissolution of mesoporous silica supports in aqueous solutions: Implications for mesoporous silica-based water treatment processes

(2012) Anh Le-Tuan Pham et al.   APPLIED CATALYSIS B-ENVIRONMENTAL

IL-6 augmented motility of airway epithelial cell BEAS-2B via Akt/GSK-3β signaling pathway

(2012) Wei-Chun Wang et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Efficient internalization and intracellular translocation of inhaled gold nanoparticles in rat alveolar macrophages

(2012) Shinji Takenaka et al.   Nanomedicine

Decreased Dissolution of ZnO by Iron Doping Yields Nanoparticles with Reduced Toxicity in the Rodent Lung and Zebrafish Embryos

(2011) Tian Xia et al.   ACS Nano

Gold Nanoparticles Induce Autophagosome Accumulation through Size-Dependent Nanoparticle Uptake and Lysosome Impairment

(2011) Xiaowei Ma et al.   ACS Nano

Induction of oxidative stress, lysosome activation and autophagy by nanoparticles in human brain-derived endothelial cells

(2011) Blanka Halamoda Kenzaoui et al.   BIOCHEMICAL JOURNAL

Role of Fe Doping in Tuning the Band Gap of TiO2for the Photo-Oxidation-Induced Cytotoxicity Paradigm

(2011) Saji George et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Mechanisms of cellular adaptation to quantum dots – the role of glutathione and transcription factor EB

(2011) Kevin D. Neibert et al.   Nanotoxicology

Canonical and non-canonical autophagy: variations on a common theme of self-eating?

(2011) Patrice Codogno et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Autophagy and the degradation of mitochondria

(2010) Scott J. Goldman et al.   MITOCHONDRION

Superparamagnetic Iron Oxide Nanoparticles Labeling of Bone Marrow Stromal (Mesenchymal) Cells Does Not Affect Their “Stemness”

(2010) Arun Balakumaran et al.   PLoS One

High Intracellular Iron Oxide Nanoparticle Concentrations Affect Cellular Cytoskeleton and Focal Adhesion Kinase-Mediated Signaling

(2010) Stefaan J. H. Soenen et al.   Small

The inhibitory effect of superparamagnetic iron oxide nanoparticle (Ferucarbotran) on osteogenic differentiation and its signaling mechanism in human mesenchymal stem cells

(2010) Ying-Chun Chen et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Understanding biophysicochemical interactions at the nano–bio interface

(2009) Andre E. Nel et al.   NATURE MATERIALS

Autophagic cell death: the story of a misnomer

(2008) Guido Kroemer et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Assessing Methods for Blood Cell Cytotoxic Responses to Inorganic Nanoparticles and Nanoparticle Aggregates

(2008) Belén Díaz et al.   Small