Photoredox catalysis in nickel-catalyzed C–H functionalization

Photocatalytic (Het)arylation of C(sp3)–H Bonds with Carbon Nitride

(2021) Saikat Das et al.   ACS Catalysis

Synthetic and Mechanistic Implications of Chlorine Photoelimination in Nickel/Photoredox C(sp3)–H Cross-Coupling

(2021) Stavros K. Kariofillis et al.   ACCOUNTS OF CHEMICAL RESEARCH

Photochemical C–H Activation Enables Nickel-Catalyzed Olefin Dicarbofunctionalization

(2021) Mark W. Campbell et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Unactivated Alkyl Halides in Transition-Metal-Catalyzed C–H Bond Alkylation

(2021) Shidheshwar B. Ankade et al.   ACS Catalysis

Photoinduced Activation of Unactivated C( sp 3 )‐H Bonds and Acylation Reactions

(2021) Chen‐Chao Ren et al.   ChemistrySelect

Site-Selective Defluorinative sp3 C–H Alkylation of Secondary Amides

(2021) Wen-Jun Yue et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

C(sp3)–H methylation enabled by peroxide photosensitization and Ni-mediated radical coupling

(2021) Aristidis Vasilopoulos et al.   SCIENCE

Dehydrogenative Coupling of Benzylic and Aldehydic C–H Bonds

(2020) Tairin Kawasaki et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

C( sp 3 )−C( sp 3 ) Cross‐Coupling of Alkyl Bromides and Ethers Mediated by Metal and Visible Light Photoredox Catalysis

(2020) Marilia S. Santos et al.   ADVANCED SYNTHESIS & CATALYSIS

Evolution of High‐Valent Nickelaelectro‐Catalyzed C–H Activation: From Cross(‐Electrophile)‐Couplings to Electrooxidative C–H Transformations

(2020) Shou-Kun Zhang et al.   CHEMISTRY-A EUROPEAN JOURNAL

Nickel/Photoredox-Catalyzed Methylation of (Hetero)aryl Chlorides Using Trimethyl Orthoformate as a Methyl Radical Source

(2020) Stavros K. Kariofillis et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Cobalt-catalysed C–H methylation for late-stage drug diversification

(2020) Stig D. Friis et al.   Nature Chemistry

Dual Catalytic Platform for Enabling sp3 α C–H Arylation and Alkylation of Benzamides

(2020) Alexander W. Rand et al.   ACS Catalysis

Transition‐Metal‐Catalyzed Carbohalogenative 1,2‐Difunctionalization of C‐C Multiple Bonds

(2020) Debojyoti bag et al.   ADVANCED SYNTHESIS & CATALYSIS

Synergistic Activation of Amides and Hydrocarbons for Direct C(sp 3 )–H Acylation Enabled by Metallaphotoredox Catalysis

(2020) Geun Seok Lee et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

When metal-catalyzed C–H functionalization meets visible-light photocatalysis

(2020) Lucas Guillemard et al.   Beilstein Journal of Organic Chemistry

Impact of Cross-Coupling Reactions in Drug Discovery and Development

(2020) Melissa J. Buskes et al.   MOLECULES

Nickel-Catalyzed Dicarbofunctionalization of Alkenes

(2020) Xiaoxu Qi et al.   ACS Catalysis

Heterogeneous Photocatalytic Organic Transformation Reactions Using Conjugated Polymers-Based Materials

(2020) Jie Xiao et al.   ACS Catalysis

Three‐Component Alkene Difunctionalization via Direct and Selective Activation of Aliphatic C‐H Bonds

(2020) Sheng Xu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Photoactive Nickel Complexes in Cross‐Coupling Catalysis

(2020) Oliver S. Wenger   CHEMISTRY-A EUROPEAN JOURNAL

Palladium-Catalyzed C(sp3)–H Bond Functionalization of Aliphatic Amines

(2019) Chuan He et al.   Chem

The Dual Role of Benzophenone in Visible-Light/Nickel Photoredox-Catalyzed C−H Arylations: Hydrogen-Atom Transfer and Energy Transfer

(2019) Abhishek Dewanji et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Transition-Metal (Pd, Ni, Mn)-Catalyzed C–C Bond Constructions Involving Unactivated Alkyl Halides and Fundamental Synthetic Building Blocks

(2019) Megan R. Kwiatkowski et al.   ACCOUNTS OF CHEMICAL RESEARCH

Nickamine and Analogous Nickel Pincer Catalysts for Cross-Coupling of Alkyl Halides and Hydrosilylation of Alkenes

(2019) Renyi Shi et al.   ACCOUNTS OF CHEMICAL RESEARCH

Enantioselective C-H Activation with Earth-Abundant 3d Transition Metals

(2019) Joachim Loup et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

α-Keto Acids: Acylating Agents in Organic Synthesis

(2019) Filipe Penteado et al.   CHEMICAL REVIEWS

Remote Allylation of Unactivated C(sp3)–H Bonds Triggered by Photogenerated Amidyl Radicals

(2019) Bin Xu et al.   ACS Catalysis

Electrochemical-/ Photoredox Aspects of Transition Metal-Catalyzed Directed C-H Bond Activations

(2019) Vikas Dwivedi et al.   ChemCatChem

Transition Metal-Catalyzed Directed C(sp3)–H Functionalization of Saturated Heterocycles

(2019) Daniele Antermite et al.   SYNTHESIS-STUTTGART

Regioselective Alkylative Cross-Coupling of Remote Unactivated C(sp3)–H Bonds

(2019) Scott M. Thullen et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Benzaldehyde- and Nickel-Catalyzed Photoredox C(sp3)–H Alkylation/Arylation with Amides and Thioethers

(2019) Xiaojia Si et al.   ORGANIC LETTERS

Carboxylation of Benzylic and Aliphatic C–H Bonds with CO2 Induced by Light/Ketone/Nickel

(2019) Naoki Ishida et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Enantioselective benzylic C–H arylation via photoredox and nickel dual catalysis

(2019) Xiaokai Cheng et al.   Nature Communications

Selective Hydrogen Atom Abstraction through Induced Bond Polarization: Direct α-Arylation of Alcohols through Photoredox, HAT, and Nickel Catalysis

(2018) Jack Twilton et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Direct Cross-Coupling of Allylic C(sp3 )−H Bonds with Aryl- and Vinylbromides by Combined Nickel and Visible-Light Catalysis

(2018) Long Huang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Organic synthesis provides opportunities to transform drug discovery

(2018) David C. Blakemore et al.   Nature Chemistry

Photochemical Nickel-Catalyzed Reductive Migratory Cross-Coupling of Alkyl Bromides with Aryl Bromides

(2018) Long Peng et al.   ORGANIC LETTERS

Highly Regioselective and E/Z-Selective Hydroalkylation of Ynone, Ynoate, and Ynamide via Photoredox Mediated Ni/Ir Dual Catalysis

(2018) Su Yong Go et al.   ORGANIC LETTERS

Enantioselective C(sp3)‒H bond activation by chiral transition metal catalysts

(2018) Tyler G. Saint-Denis et al.   SCIENCE

Beyond Friedel and Crafts: Innate Alkylation of C-H Bonds in Arenes

(2018) Gwilherm Evano et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Nickel, Cobalt and Palladium Catalysed C−H Functionalization of Un-activated C(sp3 )−H Bond

(2018) Ashish A. Mishra et al.   CHEMICAL RECORD

Energy transfer catalysis mediated by visible light: principles, applications, directions

(2018) Felix Strieth-Kalthoff et al.   CHEMICAL SOCIETY REVIEWS

sp3 C–H Arylation and Alkylation Enabled by the Synergy of Triplet Excited Ketones and Nickel Catalysts

(2018) Yangyang Shen et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Direct arylation of strong aliphatic C–H bonds

(2018) Ian B. Perry et al.   NATURE

Expanding the medicinal chemistry synthetic toolbox

(2018) Jonas Boström et al.   NATURE REVIEWS DRUG DISCOVERY

The Combination of Benzaldehyde and Nickel-Catalyzed Photoredox C(sp3 )−H Alkylation/Arylation

(2018) Lumin Zhang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Recent Advances in Alkyl Carbon-Carbon Bond Formation by Nickel/Photoredox Cross-Coupling

(2018) Gary Molander et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Amidyl Radical Directed Remote Allylation of Unactivated sp3 C−H Bonds by Organic Photoredox Catalysis

(2018) Kui Wu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

3d Transition Metals for C–H Activation

(2018) Parthasarathy Gandeepan et al.   CHEMICAL REVIEWS

Direct C–C Bond Formation from Alkanes Using Ni-Photoredox Catalysis

(2018) Laura K. G. Ackerman et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A Pharmaceutical Industry Perspective on Sustainable Metal Catalysis

(2018) John D. Hayler et al.   ORGANOMETALLICS

Transition-Metal-Catalyzed Ketone α-Alkylation and Alkenylation with Simple Alkenes and Alkynes through a Dual Activation Strategy

(2018) Guangbin Dong et al.   SYNLETT

Transition metal-catalyzed α-alkylation of amines by C(sp3)‒H bond activation

(2018) Laurine Gonnard et al.   TETRAHEDRON

Direct Aldehyde C–H Arylation and Alkylation via the Combination of Nickel, Hydrogen Atom Transfer, and Photoredox Catalysis

(2017) Xiaheng Zhang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Photoinduced Nickel-Catalyzed Chemo- and Regioselective Hydroalkylation of Internal Alkynes with Ether and Amide α-Hetero C(sp3)–H Bonds

(2017) Hong-Ping Deng et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Selective sp3 C–H alkylation via polarity-match-based cross-coupling

(2017) Chip Le et al.   NATURE

Photocatalytic α-Acylation of Ethers

(2017) Zhongdong Sun et al.   ORGANIC LETTERS

Transition metal–catalyzed alkyl-alkyl bond formation: Another dimension in cross-coupling chemistry

(2017) Junwon Choi et al.   SCIENCE

Arylation of Amide and Urea C(sp3)–H Bonds with Aryl Tosylates Generated In Situ from Phenols

(2017) Wen-Jun Zhou et al.   SYNLETT

Recent Advances in Catalytic C(sp2)–H Allylation Reactions

(2017) Neeraj Kumar Mishra et al.   ACS Catalysis

Arylation of Aniline C(sp3 )−H Bonds with Phenols via an In Situ Activation Strategy

(2017) Yong-Yuan Gui et al.   Asian Journal of Organic Chemistry

Recent advances in positional-selective alkenylations: removable guidance for twofold C–H activation

(2017) Wenbo Ma et al.   Organic Chemistry Frontiers

The merger of transition metal and photocatalysis

(2017) Jack Twilton et al.   Nature Reviews Chemistry

Direct Acylation of C(sp3 )−H Bonds Enabled by Nickel and Photoredox Catalysis

(2016) Candice L. Joe et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Applications of Palladium-Catalyzed C–N Cross-Coupling Reactions

(2016) Paula Ruiz-Castillo et al.   CHEMICAL REVIEWS

Organic Photoredox Catalysis

(2016) Nathan A. Romero et al.   CHEMICAL REVIEWS

Acylation of indoles via photoredox catalysis: a route to 3-acylindoles

(2016) Lijun Gu et al.   GREEN CHEMISTRY

Photoredox Catalysis in Organic Chemistry

(2016) Megan H. Shaw et al.   JOURNAL OF ORGANIC CHEMISTRY

A New Molecular Design Based on Thermally Activated Delayed Fluorescence for Highly Efficient Organic Light Emitting Diodes

(2016) Pachaiyappan Rajamalli et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Photochemical Nickel-Catalyzed C–H Arylation: Synthetic Scope and Mechanistic Investigations

(2016) Drew R. Heitz et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Direct C(sp3)–H Cross Coupling Enabled by Catalytic Generation of Chlorine Radicals

(2016) Benjamin J. Shields et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Native functionality in triple catalytic cross-coupling: sp3 C-H bonds as latent nucleophiles

(2016) M. H. Shaw et al.   SCIENCE

Substrate-Assisted Carbon Dioxide Activation as a Versatile Approach for Heterocyclic Synthesis

(2016) Arjan Kleij et al.   SYNTHESIS-STUTTGART

C–H functionalization of amines with aryl halides by nickel-photoredox catalysis

(2016) Derek T. Ahneman et al.   Chemical Science

Ni-Catalyzed C–C Couplings Using Alkyl Electrophiles

(2016) Takanori Iwasaki et al.   Topics in Current Chemistry

Photoredox Catalysis in Nickel-Catalyzed Cross-Coupling

(2016) Livia N. Cavalcanti et al.   Topics in Current Chemistry

Nickel-Catalyzed Aromatic C–H Functionalization

(2016) Junichiro Yamaguchi et al.   Topics in Current Chemistry

Recent Advances in Transition Metal-Catalyzed Methylation Reactions

(2015) Guobing Yan et al.   ADVANCED SYNTHESIS & CATALYSIS

Nickel Catalysts/N,N′-Bidentate Directing Groups: An Excellent Partnership in Directed C–H Activation Reactions

(2015) Luis C. Misal Castro et al.   CHEMISTRY LETTERS

Acylation of (Hetero)Arenes through CH Activation with Aroyl Surrogates

(2015) Xiao-Feng Wu   CHEMISTRY-A EUROPEAN JOURNAL

Analysis of Past and Present Synthetic Methodologies on Medicinal Chemistry: Where Have All the New Reactions Gone?

(2015) Dean G. Brown et al.   JOURNAL OF MEDICINAL CHEMISTRY

Recent advances in homogeneous nickel catalysis

(2014) Sarah Z. Tasker et al.   NATURE

Solar Synthesis: Prospects in Visible Light Photocatalysis

(2014) D. M. Schultz et al.   SCIENCE

Merging photoredox with nickel catalysis: Coupling of  -carboxyl sp3-carbons with aryl halides

(2014) Z. Zuo et al.   SCIENCE

Making C–C Bonds from Carbon Dioxide via Transition-Metal Catalysis

(2014) Charles S. Yeung et al.   TOPICS IN CATALYSIS

Profound Methyl Effects in Drug Discovery and a Call for New CH Methylation Reactions

(2013) Heike Schönherr et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Visible Light Photoredox Catalysis with Transition Metal Complexes: Applications in Organic Synthesis

(2013) Christopher K. Prier et al.   CHEMICAL REVIEWS

Triplet photosensitizers: from molecular design to applications

(2013) Jianzhang Zhao et al.   CHEMICAL SOCIETY REVIEWS

Synthetic applications of photoredox catalysis with visible light

(2013) Yumeng Xi et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Visible-Light Photoredox Catalysis

(2012) Jun Xuan et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Palladium-Catalyzed Cross-Coupling: A Historical Contextual Perspective to the 2010 Nobel Prize

(2012) Carin C. C. Johansson Seechurn et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Ruthenium-catalyzed direct oxidative alkenylation of arenes through twofold C–H bond functionalization

(2012) Sergei I. Kozhushkov et al.   Chemical Science

Magical Power of Transition Metals: Past, Present, and Future (Nobel Lecture)

(2011) Ei-ichi Negishi   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Cross-Coupling Reactions Of Organoboranes: An Easy Way To Construct CC Bonds (Nobel Lecture)

(2011) Akira Suzuki   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Intermolecular Dehydrogenative Heck Reactions

(2011) Jean Le Bras et al.   CHEMICAL REVIEWS

Transition metal-catalyzed arylation of unactivated C(sp3)–H bonds

(2011) Olivier Baudoin   CHEMICAL SOCIETY REVIEWS

Metal-catalyzed direct alkylations of (hetero)arenes via C–H bond cleavages with unactivated alkyl halides

(2010) Lutz Ackermann   CHEMICAL COMMUNICATIONS

Visible light photoredox catalysis: applications in organic synthesis

(2010) Jagan M. R. Narayanam et al.   CHEMICAL SOCIETY REVIEWS

Synthesis and Biological Evaluation of Bupropion Analogues as Potential Pharmacotherapies for Cocaine Addiction

(2009) F. Ivy Carroll et al.   JOURNAL OF MEDICINAL CHEMISTRY

Evolution of a Fourth Generation Catalyst for the Amination and Thioetherification of Aryl Halides

(2008) John F. Hartwig   ACCOUNTS OF CHEMICAL RESEARCH