Metformin reduces oxandrolone- induced depression-like behavior in rats via modulating the expression of IL-1β, IL-6, IL-10 and TNF-α

Neuroinflammation and depression: A review

(2020) Romain Troubat et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Cellular and Molecular Mechanisms of Metformin Action

(2020) Traci E LaMoia et al.   ENDOCRINE REVIEWS

The Protective Effect of Metformin against Oxandrolone-Induced Infertility in Male Rats

(2020) Abdulqader Fadhil Abed et al.   CURRENT PHARMACEUTICAL DESIGN

Metformin inhibits IL-6 signaling by decreasing IL-6R expression on multiple myeloma cells

(2019) Ameet K. Mishra et al.   LEUKEMIA

The potential effects of anabolic-androgenic steroids and growth hormone as commonly used sport supplements on the kidney: a systematic review

(2019) Dorna Davani-Davari et al.   BMC Nephrology

Effects of acarbose and metformin on the inflammatory state in newly diagnosed type 2 diabetes patients: a one-year randomized clinical study

(2019) Dan Mo et al.   Drug Design Development and Therapy

Psychomotor retardation in depression: A critical measure of the forced swim test

(2019) Gunes Unal et al.   BEHAVIOURAL BRAIN RESEARCH

Metformin ameliorates stress-induced depression-like behaviors via enhancing the expression of BDNF by activating AMPK/CREB-mediated histone acetylation

(2019) Wenting Fang et al.   JOURNAL OF AFFECTIVE DISORDERS

Neuroprotective effects of metformin on traumatic brain injury in rats associated with NF-κB and MAPK signaling pathway

(2018) Li Tao et al.   BRAIN RESEARCH BULLETIN

Revisiting the validity of the mouse forced swim test: Systematic review and meta-analysis of the effects of prototypic antidepressants

(2018) N.Z. Kara et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

Possible role of GLP-1 in antidepressant effects of metformin and exercise in CUMS mice

(2018) Weina Liu et al.   JOURNAL OF AFFECTIVE DISORDERS

Metformin – a Future Therapy for Neurodegenerative Diseases

(2017) Magdalena Markowicz-Piasecka et al.   PHARMACEUTICAL RESEARCH

Anti-Inflammatory Effects of Metformin Irrespective of Diabetes StatusNovelty and Significance

(2016) Amy R. Cameron et al.   CIRCULATION RESEARCH

Neuroinflammation and Immunity: A New Pharmacological Target in Depression

(2016) Rosalia Crupi et al.   CNS & Neurological Disorders-Drug Targets

Effect of folic acid and metformin on insulin resistance and inflammatory factors of obese children and adolescents

(2016) ElhamHashemi Dehkordi et al.   Journal of Research in Medical Sciences

Cross-tissue Analysis of Gene and Protein Expression in Normal and Cancer Tissues

(2016) Idit Kosti et al.   Scientific Reports

Inflammation: Depression Fans the Flames and Feasts on the Heat

(2015) Janice K. Kiecolt-Glaser et al.   AMERICAN JOURNAL OF PSYCHIATRY

Metformin increases APP expression and processing via oxidative stress, mitochondrial dysfunction and NF-κB activation: Use of insulin to attenuate metformin's effect

(2015) Pasquale Picone et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Pleiotropic Benefits of Metformin: Macrophage Targeting Its Anti-inflammatory Mechanisms: Figure 1

(2015) Yuichi Hattori et al.   DIABETES

Relationship between differentially expressed mRNA and mRNA-protein correlations in a xenograft model system

(2015) Antonis Koussounadis et al.   Scientific Reports

Safety and Efficacy of Oxandrolone in Growth Hormone-Treated Girls with Turner Syndrome: Evidence from Recent Studies and Recommendations for Use

(2014) T.C.J. Sas et al.   Hormone Research in Paediatrics

Anti-inflammatory mechanism of metformin and its effects in intestinal inflammation and colitis-associated colon cancer

(2013) Seong-Joon Koh et al.   JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY

Systemic Immune Activation Leads to Neuroinflammation and Sickness Behavior in Mice

(2013) Steven Biesmans et al.   MEDIATORS OF INFLAMMATION

Depression and sickness behavior are Janus-faced responses to shared inflammatory pathways

(2012) Michael Maes et al.   BMC Medicine

Pro- and anti-inflammatory cytokines expression in rat's brain and spleen exposed to chronic mild stress: Involvement in depression

(2011) Zili You et al.   BEHAVIOURAL BRAIN RESEARCH

Androgens and skeletal muscle: cellular and molecular action mechanisms underlying the anabolic actions

(2011) Vanessa Dubois et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Toll-like receptors are key players in neurodegeneration

(2011) Daniela S. Arroyo et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Cytokines in Autoimmunity: Role in Induction, Regulation, and Treatment

(2011) Kamal D. Moudgil et al.   JOURNAL OF INTERFERON AND CYTOKINE RESEARCH

Antidepressants and Neuroinflammation: Can Antidepressants Calm Glial Rage Down?

(2011) S. Hashioka   MINI-REVIEWS IN MEDICINAL CHEMISTRY

Psychoneuroimmunology Meets Neuropsychopharmacology: Translational Implications of the Impact of Inflammation on Behavior

(2011) Ebrahim Haroon et al.   NEUROPSYCHOPHARMACOLOGY

ETHICS AND METHODS FOR BIOLOGICAL RHYTHM RESEARCH ON ANIMALS AND HUMAN BEINGS

(2010) Francesco Portaluppi et al.   CHRONOBIOLOGY INTERNATIONAL

Repeated anabolic androgenic steroid treatment causes antidepressant-reversible alterations of the hypothalamic–pituitary–adrenal axis, BDNF levels and behavior

(2010) Francesco Matrisciano et al.   NEUROPHARMACOLOGY

Animal models of depression in dopamine, serotonin, and norepinephrine transporter knockout mice: prominent effects of dopamine transporter deletions

(2009) Maria T.G. Perona et al.   BEHAVIOURAL PHARMACOLOGY

Correlation of mRNA and protein in complex biological samples

(2009) Tobias Maier et al.   FEBS LETTERS

Enhancing versus Suppressive Effects of Stress on Immune Function: Implications for Immunoprotection and Immunopathology

(2009) Firdaus S. Dhabhar   NEUROIMMUNOMODULATION

Chronic mild stress generates clear depressive but ambiguous anxiety-like behaviour in rats

(2008) Hajnalka Kompagne et al.   BEHAVIOURAL BRAIN RESEARCH

From inflammation to sickness and depression: when the immune system subjugates the brain

(2007) Robert Dantzer et al.   NATURE REVIEWS NEUROSCIENCE