Anti-inflammatory mechanism of metformin and its effects in intestinal inflammation and colitis-associated colon cancer

The guggulsterone derivative GG-52 inhibits NF-κB signaling in gastric epithelial cells and ameliorates ethanol-induced gastric mucosal lesions in mice

(2012) Jung Mogg Kim et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Co-morbid diabetes in patients with Crohn’s disease predicts a greater need for surgical intervention

(2011) J. W. Harper et al.   ALIMENTARY PHARMACOLOGY & THERAPEUTICS

Fluoxetine inhibits NF-κB signaling in intestinal epithelial cells and ameliorates experimental colitis and colitis-associated colon cancer in mice

(2011) Seong-Joon Koh et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Pharmacological intervention studies using mouse models of the inflammatory bowel diseases

(2011) Iurii Koboziev et al.   INFLAMMATORY BOWEL DISEASES

Metformin inhibits P-glycoprotein expression via the NF-κB pathway and CRE transcriptional activity through AMPK activation

(2010) Hyung Gyun Kim et al.   BRITISH JOURNAL OF PHARMACOLOGY

Colorectal Cancer in Inflammatory Bowel Disease

(2010) Jonathan Potack et al.   Gut and Liver

Novel guggulsterone derivative GG-52 inhibits NF-κB signaling in intestinal epithelial cells and attenuates acute murine colitis

(2010) Jung Mogg Kim et al.   LABORATORY INVESTIGATION

Metformin suppresses azoxymethane-induced colorectal aberrant crypt foci by activating AMP-activated protein kinase

(2010) Kunihiro Hosono et al.   MOLECULAR CARCINOGENESIS

Metformin inhibits nuclear factor κB activation and decreases serum high-sensitivity C-reactive protein level in experimental atherogenesis of rabbits

(2009) Song-Nan Li et al.   HEART AND VESSELS

Metformin suppresses intestinal polyp growth in ApcMin/+ mice

(2008) Ayako Tomimoto et al.   CANCER SCIENCE

Diabetes and rheumatic diseases

(2008) Todd W Burner et al.   CURRENT OPINION IN RHEUMATOLOGY

Metformin inhibits TNF-α-induced IκB kinase phosphorylation, IκB-α degradation and IL-6 production in endothelial cells through PI3K-dependent AMPK phosphorylation

(2008) Nan-Lan Huang et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY