Androgens and skeletal muscle: cellular and molecular action mechanisms underlying the anabolic actions

Generation and analysis of an androgen-responsive myoblast cell line indicates that androgens regulate myotube protein accretion

(2014) Y. Chen et al.   JOURNAL OF ENDOCRINOLOGICAL INVESTIGATION

Notch and Wnt Signaling, Physiological Stimuli and Postnatal Myogenesis

(2012) Susan Tsivitse   International Journal of Biological Sciences

Ornithine decarboxylase is upregulated by the androgen receptor in skeletal muscle and regulates myoblast proliferation

(2011) Nicole K. L. Lee et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Trenbolone enhances myogenic differentiation by enhancing β-catenin signaling in muscle-derived stem cells of cattle

(2011) J.-X. Zhao et al.   DOMESTIC ANIMAL ENDOCRINOLOGY

Body composition changes and inhibition of fat development in vivo implicates androgen in regulation of stem cell lineage allocation

(2011) Anthony A. Semirale et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Novel evidence that testosterone promotes cell proliferation and differentiation via G protein-coupled receptors in the rat L6 skeletal muscle myoblast cell line

(2011) Rui Fu et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Skeletal Muscle Satellite Cells Are Committed to Myogenesis and Do Not Spontaneously Adopt Nonmyogenic Fates

(2011) Jessica D. Starkey et al.   JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY

Breakthrough in cachexia treatment through a novel selective androgen receptor modulator?!

(2011) Thomas Thum et al.   Journal of Cachexia Sarcopenia and Muscle

The selective androgen receptor modulator GTx-024 (enobosarm) improves lean body mass and physical function in healthy elderly men and postmenopausal women: results of a double-blind, placebo-controlled phase II trial

(2011) James T. Dalton et al.   Journal of Cachexia Sarcopenia and Muscle

Voluntary running, skeletal muscle gene expression, and signaling inversely regulated by orchidectomy and testosterone replacement

(2010) Chikwendu Ibebunjo et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

The depletion of skeletal muscle satellite cells with age is concomitant with reduced capacity of single progenitors to produce reserve progeny

(2010) Kenneth Day et al.   DEVELOPMENTAL BIOLOGY

Effect of trenbolone acetate on protein synthesis and degradation rates in fused bovine satellite cell cultures

(2010) E. Kamanga-Sollo et al.   DOMESTIC ANIMAL ENDOCRINOLOGY

Myocyte Androgen Receptors Increase Metabolic Rate and Improve Body Composition by Reducing Fat Mass

(2010) Shannon M. Fernando et al.   ENDOCRINOLOGY

Effects of a Novel Selective Androgen Receptor Modulator on Dexamethasone-Induced and Hypogonadism-Induced Muscle Atrophy

(2010) Amanda Jones et al.   ENDOCRINOLOGY

The Role of GH and IGF-I in Mediating Anabolic Effects of Testosterone on Androgen-Responsive Muscle

(2010) Carlo Serra et al.   ENDOCRINOLOGY

Regulation of skeletal myogenesis by Notch

(2010) Matthew F. Buas et al.   EXPERIMENTAL CELL RESEARCH

Effects of Testosterone on Muscle Strength, Physical Function, Body Composition, and Quality of Life in Intermediate-Frail and Frail Elderly Men: A Randomized, Double-Blind, Placebo-Controlled Study

(2010) Upendram Srinivas-Shankar et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Skeletal sexual dimorphism: relative contribution of sex steroids, GH–IGF1, and mechanical loading

(2010) Filip Callewaert et al.   JOURNAL OF ENDOCRINOLOGY

Research Resource: The Androgen Receptor Modulates Expression of Genes with Critical Roles in Muscle Development and Function

(2010) Anastasia Wyce et al.   MOLECULAR ENDOCRINOLOGY

Mesenchymal progenitors distinct from satellite cells contribute to ectopic fat cell formation in skeletal muscle

(2010) Akiyoshi Uezumi et al.   NATURE CELL BIOLOGY

MicroRNAs Are Mediators of Androgen Action in Prostate and Muscle

(2010) Ramesh Narayanan et al.   PLoS One

Myocytic androgen receptor controls the strength but not the mass of limb muscles

(2010) C. Chambon et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Follistatin induces muscle hypertrophy through satellite cell proliferation and inhibition of both myostatin and activin

(2009) Hélène Gilson et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

MicroRNA control of muscle development and disease

(2009) Andrew H Williams et al.   CURRENT OPINION IN CELL BIOLOGY

Transforming Growth Factor type β and Smad family signaling in stem cell function

(2009) Eve Seuntjens et al.   CYTOKINE & GROWTH FACTOR REVIEWS

Unraveling Androgen Action in Muscle: Genetic Tools Probing Cellular Mechanisms

(2009) Helen E. MacLean et al.   ENDOCRINOLOGY

Androgen Signaling in Myocytes Contributes to the Maintenance of Muscle Mass and Fiber Type Regulation But Not to Muscle Strength or Fatigue

(2009) Jill Ophoff et al.   ENDOCRINOLOGY

Testosterone Supplementation Reverses Sarcopenia in Aging through Regulation of Myostatin, c-Jun NH2-Terminal Kinase, Notch, and Akt Signaling Pathways

(2009) Ekaterina L. Kovacheva et al.   ENDOCRINOLOGY

Edward F. Adolph Distinguished Lecture: Muscle as an endocrine organ: IL-6 and other myokines

(2009) Bente K. Pedersen   JOURNAL OF APPLIED PHYSIOLOGY

Sex Hormones and Frailty in Older Men: The Osteoporotic Fractures in Men (MrOS) Study

(2009) Peggy M. Cawthon et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Mouse model of testosterone-induced muscle fiber hypertrophy: involvement of p38 mitogen-activated protein kinase-mediated Notch signaling

(2009) Danielle Brown et al.   JOURNAL OF ENDOCRINOLOGY

Nonsteroidal Selective Androgen Receptor Modulators (SARMs): Dissociating the Anabolic and Androgenic Activities of the Androgen Receptor for Therapeutic Benefit

(2009) Michael L. Mohler et al.   JOURNAL OF MEDICINAL CHEMISTRY

Androgen-mediated improvement of body composition and muscle function involves a novel early transcriptional program including IGF1, mechano growth factor, and induction of β-catenin

(2009) Michael A Gentile et al.   JOURNAL OF MOLECULAR ENDOCRINOLOGY

Conditional Inactivation of Androgen Receptor Gene in the Nervous System: Effects on Male Behavioral and Neuroendocrine Responses

(2009) K. Raskin et al.   JOURNAL OF NEUROSCIENCE

No change in skeletal muscle satellite cells in young and aging rat soleus muscle

(2009) Naomi E. Brooks et al.   Journal of Physiological Sciences

Dihydrotestosterone activates the MAPK pathway and modulates maximum isometric force through the EGF receptor in isolated intact mouse skeletal muscle fibres

(2009) M. M. Hamdi et al.   JOURNAL OF PHYSIOLOGY-LONDON

Interactions of sex hormone-binding globulin with target cells

(2009) William Rosner et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Insulin-like growth factor-I-induced androgen receptor activation is mediated by the PI3K/Akt pathway in C2C12 skeletal muscle cells

(2009) Won Jun Lee   MOLECULES AND CELLS

Insulin-like growth factor-I induces androgen receptor activation in differentiating C2C12 skeletal muscle cells

(2009) Hye Jin Kim et al.   MOLECULES AND CELLS

A three-dimensional view of the molecular machinery of RNA interference

(2009) Martin Jinek et al.   NATURE

Nitric oxide and repair of skeletal muscle injury

(2009) Lidiane Isabel Filippin et al.   NITRIC OXIDE-BIOLOGY AND CHEMISTRY

Effect of Testosterone on Insulin Stimulated IRS1 Ser Phosphorylation in Primary Rat Myotubes—A Potential Model for PCOS-Related Insulin Resistance

(2009) Michael C. Allemand et al.   PLoS One

Further Characterisation of the Molecular Signature of Quiescent and Activated Mouse Muscle Satellite Cells

(2009) Viola F. Gnocchi et al.   PLoS One

Muscle hypertrophy driven by myostatin blockade does not require stem/precursor-cell activity

(2009) H. Amthor et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Body Composition and Metabolic Profile in Women with Complete Androgen Insensitivity Syndrome

(2009) E. Dati et al.   Sexual Development

Physical activity in the androgen receptor knockout mouse: Evidence for reversal of androgen deficiency on cancellous bone

(2008) Jill Ophoff et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Ageing of human muscles and tendons

(2008) Marco V. Narici et al.   DISABILITY AND REHABILITATION

Regulation of Myogenic Differentiation by Androgens: Cross Talk between Androgen Receptor/ β-Catenin and Follistatin/Transforming Growth Factor-β Signaling Pathways

(2008) Rajan Singh et al.   ENDOCRINOLOGY

Impaired skeletal muscle development and function in male, but not female, genomic androgen receptor knockout mice

(2008) Helen E. MacLean et al.   FASEB JOURNAL

Differential regulation of bone and body composition in male mice with combined inactivation of androgen and estrogen receptor-α

(2008) Filip Callewaert et al.   FASEB JOURNAL

Delivery of recombinant follistatin lessens disease severity in a mouse model of spinal muscular atrophy

(2008) Ferrill F. Rose et al.   HUMAN MOLECULAR GENETICS

Notch1 is an effector of Akt and hypoxia in melanoma development

(2008) Barbara Bedogni et al.   JOURNAL OF CLINICAL INVESTIGATION

C2C12 myoblastoma cell differentiation and proliferation is stimulated by androgens and associated with a modulation of myostatin and Pax7 expression

(2008) P Diel et al.   JOURNAL OF MOLECULAR ENDOCRINOLOGY

Actin associated proteins function as androgen receptor coregulators: An implication of androgen receptor's roles in skeletal muscle

(2008) Huei-Ju Ting et al.   JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY

Changes in Muscle Mass, Muscle Strength, and Power but Not Physical Function Are Related to Testosterone Dose in Healthy Older Men

(2008) Thomas W. Storer et al.   JOURNAL OF THE AMERICAN GERIATRICS SOCIETY

Androgen receptor expression during C2C12 skeletal muscle cell line differentiation

(2008) Francesca Wannenes et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Steroidal Androgens and Nonsteroidal, Tissue-Selective Androgen Receptor Modulator, S-22, Regulate Androgen Receptor Function through Distinct Genomic and Nongenomic Signaling Pathways

(2008) Ramesh Narayanan et al.   MOLECULAR ENDOCRINOLOGY

Skeletal Muscle–Derived CD34+/45- and CD34-/45- Stem Cells Are Situated Hierarchically Upstream of Pax7+ Cells

(2008) Tetsuro Tamaki et al.   STEM CELLS AND DEVELOPMENT

MicroRNAs flex their muscles

(2008) Eva van Rooij et al.   TRENDS IN GENETICS

Myostatin signals through Pax7 to regulate satellite cell self-renewal

(2007) Craig McFarlane et al.   EXPERIMENTAL CELL RESEARCH