Tandem Catalytic Indolization/Enantioconvergent Substitution of Alcohols by Borrowing Hydrogen to Access Tricyclic Indoles

Challenges and Opportunities in Multicatalysis

(2021) Sebastián Martínez et al.   ACS Catalysis

Borrowing Hydrogen for Organic Synthesis

(2021) Benjamin G. Reed-Berendt et al.   ACS Central Science

Ternary Catalysis: A Stepping Stone toward Multicatalysis

(2020) Shashank P. Sancheti et al.   ACS Catalysis

Asymmetric Guerbet Reaction to Access Chiral Alcohols

(2020) Kun Wang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Room‐Temperature Guerbet Reaction with Unprecedented Catalytic Efficiency and Enantioselectivity

(2020) Teng Wei Ng et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Control of Absolute Stereochemistry in Transition‐Metal‐Catalyzed Hydrogen Borrowing Reactions

(2020) Timothy Kwok et al.   CHEMISTRY-A EUROPEAN JOURNAL

B(C6F5)3-Catalyzed Direct C3 Alkylation of Indoles and Oxindoles

(2020) Shyam Basak et al.   ACS Catalysis

Dynamic Kinetic Asymmetric Amination of Alcohols Assisted by Microwave: Stereoconvergent Access to Tetralin- and Indane-Derived Chiral Amines

(2020) Zi-Qiang Rong et al.   ACS Catalysis

Anti‐Markovnikov Hydroamination of Racemic Allylic Alcohols to Access Chiral γ‐Amino Alcohols

(2020) Ruirui Xu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Asymmetric Synthesis of γ-Secondary Amino Alcohols via a Borrowing-Hydrogen Cascade

(2020) Yupeng Pan et al.   ORGANIC LETTERS

Stereoconvergent, Redox-Neutral Access to Tetrahydroquinoxalines through Relay Epoxide Opening/Amination of Alcohols

(2019) Guangda Xu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Catalytic Asymmetric Synthesis of Cyclohexanes by Hydrogen Borrowing Annulations

(2019) Roly Armstrong et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Enantioselective Dearomatization of Indoles by an Azoalkene-Enabled (3+2) Reaction: Access to Pyrroloindolines

(2019) Guang-Jian Mei et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Different Strategies for Designing Dual-Catalytic Enantioselective Processes: From Fully Cooperative to Non-cooperative Systems

(2019) Filippo Romiti et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Intermolecular Metal-Catalyzed Reductive Coupling of Dienes, Allenes, and Enynes with Carbonyl Compounds and Imines

(2018) Michael Holmes et al.   CHEMICAL REVIEWS

Advances in One-Pot Synthesis through Borrowing Hydrogen Catalysis

(2018) Avelino Corma et al.   CHEMICAL REVIEWS

Iron-Catalyzed Methylation Using the Borrowing Hydrogen Approach

(2018) Kurt Polidano et al.   ACS Catalysis

3d-Metal Catalyzed N- and C-Alkylation Reactions via Borrowing Hydrogen or Hydrogen Autotransfer

(2018) Torsten Irrgang et al.   CHEMICAL REVIEWS

Iron-Catalyzed Direct C3-Benzylation of Indoles with Benzyl Alcohols through Borrowing Hydrogen

(2017) Giovanni Di Gregorio et al.   JOURNAL OF ORGANIC CHEMISTRY

Divergent Dehydrogenative Coupling of Indolines with Alcohols

(2017) Xue Jiang et al.   ACS Catalysis

Recent progress in organocatalytic asymmetric total syntheses of complex indole alkaloids

(2017) Jin Song et al.   National Science Review

(Enantio)selective Hydrogen Autotransfer: Ruthenium-Catalyzed Synthesis of Oxazolidin-2-ones from Urea and Diols

(2016) Miguel Peña-López et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Catalytic enantioselective OFF ↔ ON activation processes initiated by hydrogen transfer: concepts and challenges

(2016) Adrien Quintard et al.   CHEMICAL COMMUNICATIONS

Metal-catalyzed reductive coupling of olefin-derived nucleophiles: Reinventing carbonyl addition

(2016) Khoa D. Nguyen et al.   SCIENCE

Triple Iron/Copper/Iminium Activation for the Efficient Redox Neutral Catalytic Enantioselective Functionalization of Allylic Alcohols

(2016) Mylène Roudier et al.   ACS Catalysis

Acid-Assisted Ru-Catalyzed Enantioselective Amination of 1,2-Diols through Borrowing Hydrogen

(2016) Li-Cheng Yang et al.   ACS Catalysis

C-Alkylation of Ketones and Related Compounds by Alcohols: Transition-Metal-Catalyzed Dehydrogenation

(2015) Fei Huang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Iridium-Catalyzed Direct Synthesis of Tryptamine Derivatives from Indoles: Exploiting N-Protected β-Amino Alcohols as Alkylating Agents

(2015) Silvia Bartolucci et al.   JOURNAL OF ORGANIC CHEMISTRY

Dynamic Kinetic Asymmetric Amination of Alcohols: From A Mixture of Four Isomers to Diastereo- and Enantiopure α-Branched Amines

(2015) Zi-Qiang Rong et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Simple indole alkaloids and those with a nonrearranged monoterpenoid unit

(2015) Minoru Ishikura et al.   NATURAL PRODUCT REPORTS

A Survey of the Borrowing Hydrogen Approach to the Synthesis of some Pharmaceutically Relevant Intermediates

(2015) John Leonard et al.   ORGANIC PROCESS RESEARCH & DEVELOPMENT

Conversion of alcohols to enantiopure amines through dual-enzyme hydrogen-borrowing cascades

(2015) F. G. Mutti et al.   SCIENCE

Catalytic Enantioselective CH Functionalization of Alcohols by Redox-Triggered Carbonyl Addition: Borrowing Hydrogen, Returning Carbon

(2014) John M. Ketcham et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Complete Field Guide to Asymmetric BINOL-Phosphate Derived Brønsted Acid and Metal Catalysis: History and Classification by Mode of Activation; Brønsted Acidity, Hydrogen Bonding, Ion Pairing, and Metal Phosphates

(2014) Dixit Parmar et al.   CHEMICAL REVIEWS

Catalytic Asymmetric Reactions by Metal and Chiral Phosphoric Acid Sequential Catalysis

(2014) Ze-Peng Yang et al.   JOURNAL OF ORGANIC CHEMISTRY

From Racemic Alcohols to Enantiopure Amines: Ru-Catalyzed Diastereoselective Amination

(2014) Nathan J. Oldenhuis et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Bioinspired Direct Access to Benzofuroindolines by Oxidative [3 + 2] Annulation of Phenols and Indoles

(2014) Natacha Denizot et al.   ORGANIC LETTERS

Enantioselective Cascade Formal Reductive Insertion of Allylic Alcohols into the C(O)–C Bond of 1,3-Diketones: Ready Access to Synthetically Valuable 3-Alkylpentanol Units

(2014) Mylène Roudier et al.   ORGANIC LETTERS

Asymmetric Relay Catalysis Reaction Consisting of Metal Complex and Chiral Phosphoric Acids

(2013) Xiang Wu et al.   ACTA CHIMICA SINICA

Redox Chain Reaction-Indole and Pyrrole Alkylation with Unactivated Secondary Alcohols

(2013) Xinping Han et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

An Iron/Amine-Catalyzed Cascade Process for the Enantioselective Functionalization of Allylic Alcohols

(2013) Adrien Quintard et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Catalytic Enantioselective Amination of Alcohols by the Use of Borrowing Hydrogen Methodology: Cooperative Catalysis by Iridium and a Chiral Phosphoric Acid

(2013) Yao Zhang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Ruthenium-Catalyzed Enantioselective Synthesis of β-Amino Alcohols from 1,2-Diols by “Borrowing Hydrogen”

(2013) Anggi Eka Putra et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

A robustness screen for the rapid assessment of chemical reactions

(2013) Karl D. Collins et al.   Nature Chemistry

Applications of Acceptorless Dehydrogenation and Related Transformations in Chemical Synthesis

(2013) C. Gunanathan et al.   SCIENCE

Recent Advances in Iridium-Catalyzed Alkylation of C–H and N–H Bonds

(2013) Shiguang Pan et al.   ACS Catalysis

Organocatalyzed Enantioselective Formal [4 + 2] Cycloaddition of 2,3-Disubstituted Indole and Methyl Vinyl Ketone

(2012) Quan Cai et al.   ORGANIC LETTERS

Catalyzed Tandem C–N/C–C Bond Formation for the Synthesis of Tricyclic Indoles using Ir(III) Pyrazolyl-1,2,3-Triazolyl Complexes

(2012) Chin Min Wong et al.   ORGANOMETALLICS

The Catalytic Amination of Alcohols

(2011) Sebastian Bähn et al.   ChemCatChem

Use of an Iridium-Catalyzed Redox-Neutral Alcohol-Amine Coupling on Kilogram Scale for the Synthesis of a GlyT1 Inhibitor

(2011) Martin A. Berliner et al.   ORGANIC PROCESS RESEARCH & DEVELOPMENT

Selective Ruthenium-Catalyzed Alkylation of Indoles by Using Amines

(2010) Sebastian Imm et al.   CHEMISTRY-A EUROPEAN JOURNAL

Borrowing Hydrogen in Water and Ionic Liquids: Iridium-Catalyzed Alkylation of Amines with Alcohols

(2010) Ourida Saidi et al.   ORGANIC PROCESS RESEARCH & DEVELOPMENT

The Give and Take of Alcohol Activation

(2010) A. J. A. Watson et al.   SCIENCE

Homo- and Heterodinuclear Complexes with Triazolyl-diylidene. An Easy Approach to Tandem Catalysts

(2008) Alessandro Zanardi et al.   ORGANOMETALLICS