Monitoring the Activation of Caspases-1/3/4 for Describing the Pyroptosis Pathways of Cancer Cells

Promoted “Click” SERS Detection for Precise Intracellular Imaging of Caspase-3

(2021) Wei Zhu et al.   ANALYTICAL CHEMISTRY

Structural Mechanism for GSDMD Targeting by Autoprocessed Caspases in Pyroptosis

(2020) Kun Wang et al.   CELL

A PLK1 kinase inhibitor enhances the chemosensitivity of cisplatin by inducing pyroptosis in oesophageal squamous cell carcinoma

(2019) Mengjiao Wu et al.   EBioMedicine

Real-Time in Situ Visualizing of the Sequential Activation of Caspase Cascade Using a Multicolor Gold–Selenium Bonding Fluorescent Nanoprobe

(2019) Xiaojun Liu et al.   ANALYTICAL CHEMISTRY

Caspases in Cell Death, Inflammation, and Disease

(2019) Nina Van Opdenbosch et al.   IMMUNITY

The role of pyroptosis in cancer: pro-cancer or pro-“host”?

(2019) Xiaojing Xia et al.   Cell Death & Disease

Non-invasive in vivo imaging of caspase-1 activation enables rapid and spatiotemporal detection of acute and chronic inflammatory disorders

(2019) Young Ji Ko et al.   BIOMATERIALS

Au–Se-Bond-Based Nanoprobe for Imaging MMP-2 in Tumor Cells under a High-Thiol Environment

(2018) Xiaonan Gao et al.   ANALYTICAL CHEMISTRY

Avoiding Thiol Compound Interference: A Nanoplatform Based on High-Fidelity Au-Se Bonds for Biological Applications

(2018) Bo Hu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

DPP8/DPP9 inhibitor-induced pyroptosis for treatment of acute myeloid leukemia

(2018) Darren C. Johnson et al.   NATURE MEDICINE

Therapeutically active RIG-I agonist induces immunogenic tumor cell killing in breast cancers

(2018) David L Elion et al.   CANCER RESEARCH

Molecular mechanisms and functions of pyroptosis, inflammatory caspases and inflammasomes in infectious diseases

(2017) Si Ming Man et al.   IMMUNOLOGICAL REVIEWS

Chemotherapy drugs induce pyroptosis through caspase-3 cleavage of a gasdermin

(2017) Yupeng Wang et al.   NATURE

Pyroptosis is driven by non-selective gasdermin-D pore and its morphology is different from MLKL channel-mediated necroptosis

(2016) Xin Chen et al.   CELL RESEARCH

Inflammasome-activated gasdermin D causes pyroptosis by forming membrane pores

(2016) Xing Liu et al.   NATURE

Pyroptosis is involved in the pathogenesis of human hepatocellular carcinoma

(2016) Qun Chu et al.   Oncotarget

Mechanisms of unconventional secretion of IL-1 family cytokines

(2015) Mercedes Monteleone et al.   CYTOKINE

Caspase-11 cleaves gasdermin D for non-canonical inflammasome signalling

(2015) Nobuhiko Kayagaki et al.   NATURE

Cleavage of GSDMD by inflammatory caspases determines pyroptotic cell death

(2015) Jianjin Shi et al.   NATURE

Necroptosis and its role in inflammation

(2015) Manolis Pasparakis et al.   NATURE

Mechanisms of inflammasome activation: recent advances and novel insights

(2015) Sivapriya K. Vanaja et al.   TRENDS IN CELL BIOLOGY

In situ activation and monitoring of the evolution of the intracellular caspase family

(2015) Lei Zhang et al.   Chemical Science

Inflammatory caspases are innate immune receptors for intracellular LPS

(2014) Jianjin Shi et al.   NATURE

Cytoplasmic LPS Activates Caspase-11: Implications in TLR4-Independent Endotoxic Shock

(2013) J. A. Hagar et al.   SCIENCE

Cascade imaging of proteolytic pathways in cancer cells using fluorescent protein-conjugated gold nanoquenchers

(2012) Kyoungsook Park et al.   CHEMICAL COMMUNICATIONS

Caspase-1 Promiscuity Is Counterbalanced by Rapid Inactivation of Processed Enzyme

(2011) John G. Walsh et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Porphyrin FRET Acceptors for Apoptosis Induction and Monitoring

(2011) Jonathan F. Lovell et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Non-canonical inflammasome activation targets caspase-11

(2011) Nobuhiko Kayagaki et al.   NATURE

Inflammatory Stimuli Regulate Caspase Substrate Profiles

(2010) Nicholas J. Agard et al.   MOLECULAR & CELLULAR PROTEOMICS

Recent progress in tumor pH targeting nanotechnology

(2008) Eun Seong Lee et al.   JOURNAL OF CONTROLLED RELEASE