Inflammatory Stimuli Regulate Caspase Substrate Profiles

Anthrax Lethal Toxin Triggers the Formation of a Membrane-Associated Inflammasome Complex in Murine Macrophages

(2009) A. M. Nour et al.   INFECTION AND IMMUNITY

Human Caspases: Activation, Specificity, and Regulation

(2009) Cristina Pop et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

AIM2 activates the inflammasome and cell death in response to cytoplasmic DNA

(2009) Teresa Fernandes-Alnemri et al.   NATURE

AIM2 recognizes cytosolic dsDNA and forms a caspase-1-activating inflammasome with ASC

(2009) Veit Hornung et al.   NATURE

An orthogonal proteomic-genomic screen identifies AIM2 as a cytoplasmic DNA sensor for the inflammasome

(2009) Tilmann Bürckstümmer et al.   NATURE IMMUNOLOGY

Mechanisms of regulated unconventional protein secretion

(2009) Walter Nickel et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Two-state selection of conformation-specific antibodies

(2009) J. Gao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

HIN-200 Proteins Regulate Caspase Activation in Response to Foreign Cytoplasmic DNA

(2009) T. L. Roberts et al.   SCIENCE

The familial Mediterranean fever protein, pyrin, is cleaved by caspase-1 and activates NF- B through its N-terminal fragment

(2008) J. J. Chae et al.   BLOOD

Global Sequencing of Proteolytic Cleavage Sites in Apoptosis by Specific Labeling of Protein N Termini

(2008) Sami Mahrus et al.   CELL

Global Mapping of the Topography and Magnitude of Proteolytic Events in Apoptosis

(2008) Melissa M. Dix et al.   CELL

Metadegradomics

(2008) Alain Doucet et al.   MOLECULAR & CELLULAR PROTEOMICS

Targeted Peptidecentric Proteomics Reveals Caspase-7 as a Substrate of the Caspase-1 Inflammasomes

(2008) Mohamed Lamkanfi et al.   MOLECULAR & CELLULAR PROTEOMICS

The Nalp3 inflammasome is essential for the development of silicosis

(2008) Suzanne L. Cassel et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Anthrax lethal toxin and Salmonella elicit the common cell death pathway of caspase-1-dependent pyroptosis via distinct mechanisms

(2008) S. L. Fink et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Executioner caspase-3 and caspase-7 are functionally distinct proteases

(2008) J. G. Walsh et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA