Engineering the Deformability of Albumin‐Stabilized Emulsions for Lymph‐Node Vaccine Delivery

Metabolic labeling and targeted modulation of dendritic cells

(2020) Hua Wang et al.   NATURE MATERIALS

Programmable multistage drug delivery to lymph nodes

(2020) Alex Schudel et al.   Nature Nanotechnology

Engineering Strategies for Lymph Node Targeted Immune Activation

(2020) Yong Chen et al.   ACCOUNTS OF CHEMICAL RESEARCH

Synthetic Particles for Cancer Vaccines: Connecting the Inherent Supply Chain

(2020) Yufei Xia et al.   ACCOUNTS OF CHEMICAL RESEARCH

Particulate Alum via Pickering Emulsion for an Enhanced COVID‐19 Vaccine Adjuvant

(2020) Sha Peng et al.   ADVANCED MATERIALS

A DNA nanodevice-based vaccine for cancer immunotherapy

(2020) Shaoli Liu et al.   NATURE MATERIALS

Engineering nanoparticulate vaccines for enhancing antigen cross-presentation

(2020) Guangsheng Du et al.   CURRENT OPINION IN BIOTECHNOLOGY

Viscoelastic characterization of the crosslinking of β-lactoglobulin on emulsion drops via microcapsule compression and interfacial dilational and shear rheology

(2020) Matthew D. Biviano et al.   JOURNAL OF COLLOID AND INTERFACE SCIENCE

Induction of Potent Neutralizing Antibody Responses by a Designed Protein Nanoparticle Vaccine for Respiratory Syncytial Virus

(2019) Jessica Marcandalli et al.   CELL

Tailoring Nanomaterials for Targeting Tumor‐Associated Macrophages

(2019) Muhammad Ovais et al.   ADVANCED MATERIALS

Material design for lymph node drug delivery

(2019) Alex Schudel et al.   Nature Reviews Materials

Materials for Immunotherapy

(2019) C. Wyatt Shields et al.   ADVANCED MATERIALS

A multipeptide vaccine plus toll-like receptor agonists LPS or polyICLC in combination with incomplete Freund’s adjuvant in melanoma patients

(2019) Marit M. Melssen et al.   Journal for ImmunoTherapy of Cancer

Immunization with mannosylated nanovaccines and inhibition of the immune-suppressing microenvironment sensitizes melanoma to immune checkpoint modulators

(2019) João Conniot et al.   Nature Nanotechnology

Exploiting the Lymph-Node-Amplifying Effect for Potent Systemic and Gastrointestinal Immune Responses via Polymer/Lipid Nanoparticles

(2019) Yiqun Du et al.   ACS Nano

Lymphatic System Flows

(2018) James E. Moore et al.   Annual Review of Fluid Mechanics

Vaccine adjuvants: Softness makes it better

(2018) Herman F. Staats et al.   NATURE MATERIALS

Exploiting the pliability and lateral mobility of Pickering emulsion for enhanced vaccination

(2018) Yufei Xia et al.   NATURE MATERIALS

Sustained micellar delivery via inducible transitions in nanostructure morphology

(2018) Nicholas B. Karabin et al.   Nature Communications

Nanoparticle elasticity directs tumor uptake

(2018) Peng Guo et al.   Nature Communications

Immunomodulating Nanomedicine for Cancer Therapy

(2018) Zhigang Liu et al.   NANO LETTERS

Biomaterial-assisted targeted modulation of immune cells in cancer treatment

(2018) Hua Wang et al.   NATURE MATERIALS

Functional Nanomaterials Optimized to Circumvent Tumor Immunological Tolerance

(2018) Ningqiang Gong et al.   ADVANCED FUNCTIONAL MATERIALS

Nanoparticle-Conjugate TLR7/8 Agonist Localized Immunotherapy Provokes Safe Antitumoral Responses

(2018) Lutz Nuhn et al.   ADVANCED MATERIALS

Innate immune recognition of glycans targets HIV nanoparticle immunogens to germinal centers

(2018) Talar Tokatlian et al.   SCIENCE

Lymph node targeting strategies to improve vaccination efficacy

(2017) Hao Jiang et al.   JOURNAL OF CONTROLLED RELEASE

Mechanistic understanding of nanoparticles’ interactions with extracellular matrix: the cell and immune system

(2017) Ayse Basak Engin et al.   Particle and Fibre Toxicology

Numerical Simulation of Real-Time Deformability Cytometry To Extract Cell Mechanical Properties

(2017) M. Mokbel et al.   ACS Biomaterials-Science & Engineering

Turning the Old Adjuvant from Gel to Nanoparticles to Amplify CD8+ T Cell Responses

(2017) Hao Jiang et al.   Advanced Science

Numerical Simulation of Real-Time Deformability Cytometry To Extract Cell Mechanical Properties

(2017) M. Mokbel et al.   ACS Biomaterials Science & Engineering

A Powerful CD8+T-Cell Stimulating D-Tetra-Peptide Hydrogel as a Very Promising Vaccine Adjuvant

(2016) Zichao Luo et al.   ADVANCED MATERIALS

Rapid and Continued T-Cell Differentiation into Long-term Effector and Memory Stem Cells in Vaccinated Melanoma Patients

(2016) Philippe O. Gannon et al.   CLINICAL CANCER RESEARCH

Lipid Nanoparticle Assisted mRNA Delivery for Potent Cancer Immunotherapy

(2016) Matthias A. Oberli et al.   NANO LETTERS

Designer vaccine nanodiscs for personalized cancer immunotherapy

(2016) Rui Kuai et al.   NATURE MATERIALS

Flexible Macromolecule versus Rigid Particle Retention in the Injected Skin and Accumulation in Draining Lymph Nodes Are Differentially Influenced by Hydrodynamic Size

(2016) Nathan Andrew Rohner et al.   ACS Biomaterials-Science & Engineering

Flexible Macromolecule versus Rigid Particle Retention in the Injected Skin and Accumulation in Draining Lymph Nodes Are Differentially Influenced by Hydrodynamic Size

(2016) Nathan Andrew Rohner et al.   ACS Biomaterials Science & Engineering

Synthetic Nanoparticles for Vaccines and Immunotherapy

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The Development of Self-Emulsifying Oil-in-Water Emulsion Adjuvant and an Evaluation of the Impact of Droplet Size on Performance

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From sewer to saviour — targeting the lymphatic system to promote drug exposure and activity

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Injectable, Pore-Forming Hydrogels for In Vivo Enrichment of Immature Dendritic Cells

(2015) Catia S. Verbeke et al.   Advanced Healthcare Materials

Injectable, spontaneously assembling, inorganic scaffolds modulate immune cells in vivo and increase vaccine efficacy

(2014) Jaeyun Kim et al.   NATURE BIOTECHNOLOGY

The atypical chemokine receptor CCRL1 shapes functional CCL21 gradients in lymph nodes

(2014) Maria H Ulvmar et al.   NATURE IMMUNOLOGY

Determination of local and global elastic moduli of valve interstitial cells cultured on soft substrates

(2013) Haijiao Liu et al.   JOURNAL OF BIOMECHANICS

Engineering synthetic vaccines using cues from natural immunity

(2013) Darrell J. Irvine et al.   NATURE MATERIALS

Hydrogels preserve native phenotypes of valvular fibroblasts through an elasticity-regulated PI3K/AKT pathway

(2013) H. Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The mechanism of action of MF59 – An innately attractive adjuvant formulation

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A multifunctional core–shell nanoparticle for dendritic cell-based cancer immunotherapy

(2011) Nam-Hyuk Cho et al.   Nature Nanotechnology

Mechanisms and Consequences of Dendritic Cell Migration

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