Injectable, spontaneously assembling, inorganic scaffolds modulate immune cells in vivo and increase vaccine efficacy

Germinal Centers

(2012) Gabriel D. Victora et al.   Annual Review of Immunology

Mesoporous silica nanoparticles in biomedical applications

(2012) Zongxi Li et al.   CHEMICAL SOCIETY REVIEWS

Functionalized mesoporous silica materials for controlled drug delivery

(2012) Piaoping Yang et al.   CHEMICAL SOCIETY REVIEWS

Processing Pathway Dependence of Amorphous Silica Nanoparticle Toxicity: Colloidal vs Pyrolytic

(2012) Haiyuan Zhang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Synthetic mast-cell granules as adjuvants to promote and polarize immunity in lymph nodes

(2012) Ashley L. St. John et al.   NATURE MATERIALS

Combination delivery of TGF-β inhibitor and IL-2 by nanoscale liposomal polymeric gels enhances tumour immunotherapy

(2012) Jason Park et al.   NATURE MATERIALS

Enhancing humoral responses to a malaria antigen with nanoparticle vaccines that expand Tfh cells and promote germinal center induction

(2012) J. J. Moon et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Follicular Helper CD4 T Cells (TFH)

(2011) Shane Crotty   Annual Review of Immunology

The induction of innate and adaptive immunity by biodegradable poly(γ-glutamic acid) nanoparticles via a TLR4 and MyD88 signaling pathway

(2011) Tomofumi Uto et al.   BIOMATERIALS

Antigen depot is not required for alum adjuvanticity

(2011) Sharon Hutchison et al.   FASEB JOURNAL

Synthesis, toxicology and potential of ordered mesoporous materials in nanomedicine

(2011) Alfonso E Garcia-Bennett   Nanomedicine

Interbilayer-crosslinked multilamellar vesicles as synthetic vaccines for potent humoral and cellular immune responses

(2011) James J. Moon et al.   NATURE MATERIALS

Chimeric Antigen Receptor–Modified T Cells in Chronic Lymphoid Leukemia

(2011) David L. Porter et al.   NEW ENGLAND JOURNAL OF MEDICINE

Dendritic Cell-Based Immunotherapy for Prostate Cancer

(2010) Hanka Jähnisch et al.   Clinical & Developmental Immunology

GM-CSF-induced, bone-marrow-derived dendritic cells can expand natural Tregs and induce adaptive Tregs by different mechanisms

(2010) Palash Bhattacharya et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Autonomous in Vitro Anticancer Drug Release from Mesoporous Silica Nanoparticles by pH-Sensitive Nanovalves

(2010) Huan Meng et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

The three-stage in vitro degradation behavior of mesoporous silica in simulated body fluid

(2010) Qianjun He et al.   MICROPOROUS AND MESOPOROUS MATERIALS

Therapeutic cell engineering with surface-conjugated synthetic nanoparticles

(2010) Matthias T Stephan et al.   NATURE MEDICINE

Mimicking nature by codelivery of stimulant and inhibitor to create temporally stable and spatially restricted angiogenic zones

(2010) W. W. Yuen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Polyethyleneimine Coating Enhances the Cellular Uptake of Mesoporous Silica Nanoparticles and Allows Safe Delivery of siRNA and DNA Constructs

(2009) Tian Xia et al.   ACS Nano

Synthetic polymer scaffolds for tissue engineering

(2009) Elsie S. Place et al.   CHEMICAL SOCIETY REVIEWS

Bio-degradation study of colloidal mesoporous silica nanoparticles: Effect of surface functionalization with organo-silanes and poly(ethylene glycol)

(2009) Valentina Cauda et al.   MICROPOROUS AND MESOPOROUS MATERIALS

Infection-mimicking materials to program dendritic cells in situ

(2009) Omar A. Ali et al.   NATURE MATERIALS

Uptake of particulate vaccine adjuvants by dendritic cells activates the NALP3 inflammasome

(2009) Fiona A. Sharp et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

In Situ Regulation of DC Subsets and T Cells Mediates Tumor Regression in Mice

(2009) O. A. Ali et al.   Science Translational Medicine

Multifunctional Uniform Nanoparticles Composed of a Magnetite Nanocrystal Core and a Mesoporous Silica Shell for Magnetic Resonance and Fluorescence Imaging and for Drug Delivery

(2008) Jaeyun Kim et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

The biocompatibility of mesoporous silicates

(2008) Sarah P. Hudson et al.   BIOMATERIALS

Silica crystals and aluminum salts activate the NALP3 inflammasome through phagosomal destabilization

(2008) Veit Hornung et al.   NATURE IMMUNOLOGY

Accordion-like honeycombs for tissue engineering of cardiac anisotropy

(2008) George C. Engelmayr et al.   NATURE MATERIALS

Innate Immune Activation Through Nalp3 Inflammasome Sensing of Asbestos and Silica

(2008) C. Dostert et al.   SCIENCE

Migration of Dendritic Cell Subsets and their Precursors

(2007) Gwendalyn J. Randolph et al.   Annual Review of Immunology