Mesenchymal Stem Cell-Derived Exosomes and Their Therapeutic Potential for Osteoarthritis
Published 2021 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Mesenchymal Stem Cell-Derived Exosomes and Their Therapeutic Potential for Osteoarthritis
Authors
Keywords
-
Journal
Biology-Basel
Volume 10, Issue 4, Pages 285
Publisher
MDPI AG
Online
2021-04-01
DOI
10.3390/biology10040285
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- MSC Based Therapies—New Perspectives for the Injured Lung
- (2020) Judith Behnke et al. Journal of Clinical Medicine
- Bone Marrow Aspirate Concentrate: Its Uses in Osteoarthritis
- (2020) Gi Beom Kim et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Intra-Articular Injection of Autologous Adipose Tissue-Derived Mesenchymal Stem Cells for the Treatment of Knee Osteoarthritis: A Phase IIb, Randomized, Placebo-Controlled Clinical Trial
- (2019) Woo-Suk Lee et al. Stem Cells Translational Medicine
- Exosomes derived from mesenchymal stem cells inhibit mitochondrial dysfunction-induced apoptosis of chondrocytes via p38, ERK, and Akt pathways
- (2019) Hui Qi et al. IN VITRO CELLULAR & DEVELOPMENTAL BIOLOGY-ANIMAL
- Bioactive factors for cartilage repair and regeneration: Improving delivery, retention, and activity
- (2019) Jay M. Patel et al. Acta Biomaterialia
- MSC exosomes alleviate temporomandibular joint osteoarthritis by attenuating inflammation and restoring matrix homeostasis
- (2019) Shipin Zhang et al. BIOMATERIALS
- Mesenchymal Stem Cell-Based Therapy of Inflammatory Lung Diseases: Current Understanding and Future Perspectives
- (2019) C. Randall Harrell et al. Stem Cells International
- Review of the Isolation, Characterization, Biological Function, and Multifarious Therapeutic Approaches of Exosomes
- (2019) Sangiliyandi Gurunathan et al. Cells
- Defining mesenchymal stromal cell (MSC)-derived small extracellular vesicles for therapeutic applications
- (2019) Kenneth W. Witwer et al. Journal of Extracellular Vesicles
- Mesenchymal stem cell-derived exosomes: a new therapeutic approach to osteoarthritis?
- (2019) Elaheh Mianehsaz et al. Stem Cell Research & Therapy
- MSC exosomes mediate cartilage repair by enhancing proliferation, attenuating apoptosis and modulating immune reactivity
- (2018) Shipin Zhang et al. BIOMATERIALS
- Exosomes and Stem Cells in Degenerative Disease Diagnosis and Therapy
- (2018) Yu-Hsun Chang et al. CELL TRANSPLANTATION
- Microvesicles from Human Adipose Tissue-Derived Mesenchymal Stem Cells as a New Protective Strategy in Osteoarthritic Chondrocytes
- (2018) Miguel Tofiño-Vian et al. CELLULAR PHYSIOLOGY AND BIOCHEMISTRY
- Identification of distinct nanoparticles and subsets of extracellular vesicles by asymmetric flow field-flow fractionation
- (2018) Haiying Zhang et al. NATURE CELL BIOLOGY
- Mesenchymal Stromal/stem Cell-derived Extracellular Vesicles Promote Human Cartilage Regeneration In Vitro
- (2018) Lucienne A. Vonk et al. Theranostics
- Expression of exosomal microRNAs during chondrogenic differentiation of human bone mesenchymal stem cells
- (2018) Hao Sun et al. JOURNAL OF CELLULAR BIOCHEMISTRY
- Exosomes derived from miR-92a-3p-overexpressing human mesenchymal stem cells enhance chondrogenesis and suppress cartilage degradation via targeting WNT5A
- (2018) Guping Mao et al. Stem Cell Research & Therapy
- Mesenchymal stem cell-based therapy of osteoarthritis: Current knowledge and future perspectives
- (2018) C. Randall Harrell et al. BIOMEDICINE & PHARMACOTHERAPY
- Exosomes Derived From Low-Intensity Pulsed Ultrasound-Treated Dendritic Cells Suppress Tumor Necrosis Factor-Induced Endothelial Inflammation
- (2018) Xuefeng Li et al. JOURNAL OF ULTRASOUND IN MEDICINE
- Exosomes: From Garbage Bins to Promising Therapeutic Targets
- (2017) Mohammed H. Rashed et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Mesenchymal Stem/Stromal Cell-Derived Extracellular Vesicles and Their Potential as Novel Immunomodulatory Therapeutic Agents
- (2017) Verena Börger et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- CD56 + /CD16 − Natural Killer cells expressing the inflammatory protease granzyme A are enriched in synovial fluid from patients with osteoarthritis
- (2017) P. Jaime et al. OSTEOARTHRITIS AND CARTILAGE
- Extracellular Vesicles from Adipose-Derived Mesenchymal Stem Cells Downregulate Senescence Features in Osteoarthritic Osteoblasts
- (2017) Miguel Tofiño-Vian et al. Oxidative Medicine and Cellular Longevity
- MSC exosome as a cell-free MSC therapy for cartilage regeneration: Implications for osteoarthritis treatment
- (2017) Wei Seong Toh et al. SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY
- Concise Review: MSC-Derived Exosomes for Cell-Free Therapy
- (2017) Donald G. Phinney et al. STEM CELLS
- Cellular Functions and Molecular Mechanisms of the ESCRT Membrane-Scission Machinery
- (2017) Liliane Christ et al. TRENDS IN BIOCHEMICAL SCIENCES
- Human adipose‑derived mesenchymal stem cell‑conditioned media suppresses inflammatory bone loss in a lipopolysaccharide‑induced murine model
- (2017) Yu Li et al. Experimental and Therapeutic Medicine
- Exosomes maintain cellular homeostasis by excreting harmful DNA from cells
- (2017) Akiko Takahashi et al. Nature Communications
- Mesenchymal stem cells derived exosomes and microparticles protect cartilage and bone from degradation in osteoarthritis
- (2017) Stella Cosenza et al. Scientific Reports
- Comparison of exosomes secreted by induced pluripotent stem cell-derived mesenchymal stem cells and synovial membrane-derived mesenchymal stem cells for the treatment of osteoarthritis
- (2017) Yu Zhu et al. Stem Cell Research & Therapy
- Exosomes from embryonic mesenchymal stem cells alleviate osteoarthritis through balancing synthesis and degradation of cartilage extracellular matrix
- (2017) Yafei Wang et al. Stem Cell Research & Therapy
- Progress in Exosome Isolation Techniques
- (2017) Pin Li et al. Theranostics
- Concise Review: Developing Best-Practice Models for the Therapeutic Use of Extracellular Vesicles
- (2017) Agnes T. Reiner et al. Stem Cells Translational Medicine
- Exosomes and the Prion Protein: More than One Truth
- (2017) Alexander Hartmann et al. Frontiers in Neuroscience
- Mesenchymal Stem Cell-Conditioned Medium Reduces Disease Severity and Immune Responses in Inflammatory Arthritis
- (2017) Alasdair G. Kay et al. Scientific Reports
- Mesenchymal stem cell therapy in the treatment of osteoarthritis: reparative pathways, safety and efficacy – a review
- (2016) Julien Freitag et al. BMC MUSCULOSKELETAL DISORDERS
- Extracellular vesicles: interneural shuttles of complex messages
- (2016) Eva-Maria Krämer-Albers et al. CURRENT OPINION IN NEUROBIOLOGY
- Exosomes derived from human embryonic mesenchymal stem cells promote osteochondral regeneration
- (2016) S. Zhang et al. OSTEOARTHRITIS AND CARTILAGE
- Intra-articular treatment of knee osteoarthritis: from anti-inflammatories to products of regenerative medicine
- (2016) Masters M. Richards et al. PHYSICIAN AND SPORTSMEDICINE
- Enhanced Cardioprotection by Human Endometrium Mesenchymal Stem Cells Driven by Exosomal MicroRNA-21
- (2016) Kan Wang et al. Stem Cells Translational Medicine
- Hijacking the Cellular Mail: Exosome Mediated Differentiation of Mesenchymal Stem Cells
- (2016) Raghuvaran Narayanan et al. Stem Cells International
- Mesenchymal Stem Cell-Derived Extracellular Vesicles Promote Angiogenesis: Potencial Clinical Application
- (2016) Consuelo Merino-González et al. Frontiers in Physiology
- Resolution of Inflammation: What Controls Its Onset?
- (2016) Michelle A. Sugimoto et al. Frontiers in Immunology
- Cells release subpopulations of exosomes with distinct molecular and biological properties
- (2016) Eduard Willms et al. Scientific Reports
- Therapeutic application of mesenchymal stem cells in osteoarthritis
- (2015) Maxime Ruiz et al. EXPERT OPINION ON BIOLOGICAL THERAPY
- Therapeutic Potential of Multipotent Mesenchymal Stromal Cells and Their Extracellular Vesicles
- (2015) Nina Heldring et al. HUMAN GENE THERAPY
- Mesenchymal stromal cells and the innate immune response
- (2015) Katarina Le Blanc et al. IMMUNOLOGY LETTERS
- Mesenchymal stem cell therapy for knee osteoarthritis: 5 years follow-up of three patients
- (2015) Fereydoun Davatchi et al. International Journal of Rheumatic Diseases
- Integrated isolation and quantitative analysis of exosome shuttled proteins and nucleic acids using immunocapture approaches
- (2015) Natasa Zarovni et al. METHODS
- Integrated systems for exosome investigation
- (2015) Maureen F. Peterson et al. METHODS
- Ultrafiltration with size-exclusion liquid chromatography for high yield isolation of extracellular vesicles preserving intact biophysical and functional properties
- (2015) Joel Z. Nordin et al. Nanomedicine-Nanotechnology Biology and Medicine
- Treatment of Knee Osteoarthritis With Allogeneic Bone Marrow Mesenchymal Stem Cells
- (2015) Aurelio Vega et al. TRANSPLANTATION
- Mesenchymal Stem Cells Suppress Fibroblast Proliferation and Reduce Skin Fibrosis Through a TGF-β3-Dependent Activation
- (2015) Yan Wu et al. International Journal of Lower Extremity Wounds
- Extracellular Vesicles Improve Post-Stroke Neuroregeneration and Prevent Postischemic Immunosuppression
- (2015) Thorsten R. Doeppner et al. Stem Cells Translational Medicine
- Double-stranded DNA in exosomes: a novel biomarker in cancer detection
- (2014) Basant Kumar Thakur et al. CELL RESEARCH
- Biogenesis and secretion of exosomes
- (2014) Joanna Kowal et al. CURRENT OPINION IN CELL BIOLOGY
- Mouse bone marrow-derived mesenchymal stem cells induce macrophage M2 polarization through the nuclear factor-κB and signal transducer and activator of transcription 3 pathways
- (2014) Shuo Gao et al. EXPERIMENTAL BIOLOGY AND MEDICINE
- Transfer of T Cell Surface Molecules to Dendritic Cells upon CD4+ T Cell Priming Involves Two Distinct Mechanisms
- (2014) A. Busch et al. JOURNAL OF IMMUNOLOGY
- CD47 Signaling Regulates the Immunosuppressive Activity of VEGF in T Cells
- (2014) Sukhbir Kaur et al. JOURNAL OF IMMUNOLOGY
- Human osteoarthritic synovium impacts chondrogenic differentiation of mesenchymal stem cells via macrophage polarisation state
- (2014) N. Fahy et al. OSTEOARTHRITIS AND CARTILAGE
- Advances in Mesenchymal Stem Cell-based Strategies for Cartilage Repair and Regeneration
- (2014) Wei Seong Toh et al. Stem Cell Reviews and Reports
- Intra-Articular Injection of Mesenchymal Stem Cells for the Treatment of Osteoarthritis of the Knee: A Proof-of-Concept Clinical Trial
- (2014) Chris Hyunchul Jo et al. STEM CELLS
- Treatment of Knee Osteoarthritis With Autologous Mesenchymal Stem Cells
- (2014) Lluis Orozco et al. TRANSPLANTATION
- Exosomes from IL-1β stimulated synovial fibroblasts induce osteoarthritic changes in articular chondrocytes
- (2014) Tomohiro Kato et al. ARTHRITIS RESEARCH & THERAPY
- Mesenchymal stem cells in regenerative medicine applied to rheumatic diseases: Role of secretome and exosomes
- (2013) Marie Maumus et al. BIOCHIMIE
- Exosomes: the future of biomarkers in medicine
- (2013) Francesca Properzi et al. Biomarkers in Medicine
- Mesenchymal Stromal Cells: Sensors and Switchers of Inflammation
- (2013) Maria Ester Bernardo et al. Cell Stem Cell
- Extracellular vesicles derived from human bone marrow mesenchymal stem cells promote angiogenesis in a rat myocardial infarction model
- (2013) Suyan Bian et al. JOURNAL OF MOLECULAR MEDICINE-JMM
- Extracellular vesicles: biology and emerging therapeutic opportunities
- (2013) Samir EL Andaloussi et al. NATURE REVIEWS DRUG DISCOVERY
- Adipose mesenchymal stem cells protect chondrocytes from degeneration associated with osteoarthritis
- (2013) Marie Maumus et al. Stem Cell Research
- TLR Ligands Stimulation Protects MSC from NK Killing
- (2013) Massimo Giuliani et al. STEM CELLS
- Ongoing activation of sphingosine 1-phosphate receptors mediates maturation of exosomal multivesicular endosomes
- (2013) Taketoshi Kajimoto et al. Nature Communications
- Human adipose tissue-derived mesenchymal stem cells secrete functional neprilysin-bound exosomes
- (2013) Takeshi Katsuda et al. Scientific Reports
- Comparison of ultracentrifugation, density gradient separation, and immunoaffinity capture methods for isolating human colon cancer cell line LIM1863-derived exosomes
- (2012) Bow J. Tauro et al. METHODS
- Synovial inflammation, immune cells and their cytokines in osteoarthritis: a review
- (2012) B.J.E. de Lange-Brokaar et al. OSTEOARTHRITIS AND CARTILAGE
- Bone Marrow-Derived Mesenchymal Stem Cells Repaired but Did Not Prevent Gentamicin-Induced Acute Kidney Injury through Paracrine Effects in Rats
- (2012) Luciana A. Reis et al. PLoS One
- Safety of Cell Therapy with Mesenchymal Stromal Cells (SafeCell): A Systematic Review and Meta-Analysis of Clinical Trials
- (2012) Manoj M. Lalu et al. PLoS One
- Microvesicles Derived from Human Bone Marrow Mesenchymal Stem Cells Inhibit Tumor Growth
- (2012) Stefania Bruno et al. STEM CELLS AND DEVELOPMENT
- Secretory Mechanisms and Intercellular Transfer of MicroRNAs in Living Cells
- (2010) Nobuyoshi Kosaka et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Proteomic Analysis of Tumor Necrosis Factor-α-Induced Secretome of Human Adipose Tissue-Derived Mesenchymal Stem Cells
- (2010) Mi Jeong Lee et al. JOURNAL OF PROTEOME RESEARCH
- Role of extracellular membrane vesicles in the pathogenesis of various diseases, including cancer, renal diseases, atherosclerosis and arthritis
- (2010) H Clarke Anderson et al. LABORATORY INVESTIGATION
- A New Mesenchymal Stem Cell (MSC) Paradigm: Polarization into a Pro-Inflammatory MSC1 or an Immunosuppressive MSC2 Phenotype
- (2010) Ruth S. Waterman et al. PLoS One
- Mesenchymal stem cells suppress B-cell terminal differentiation
- (2009) Sadaki Asari et al. EXPERIMENTAL HEMATOLOGY
- Donor age and cell passage affects differentiation potential of murine bone marrow-derived stem cells
- (2008) James D Kretlow et al. BMC CELL BIOLOGY
- Fate Of Culture-Expanded Mesenchymal Stem Cells in The Microvasculature
- (2008) Catalin Toma et al. CIRCULATION RESEARCH
- Adipose-derived stem cells: Isolation, expansion and differentiation☆
- (2008) B BUNNELL et al. METHODS
- Proteomic profiling of exosomes: Current perspectives
- (2008) Richard J. Simpson et al. PROTEOMICS
- Local adherent technique for transplanting mesenchymal stem cells as a potential treatment of cartilage defect
- (2008) Hideyuki Koga et al. ARTHRITIS RESEARCH & THERAPY
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started