Immunomodulatory Effect of Microglia-Released Cytokines in Gliomas

Comparison of tumor microenvironment in primary and paired metastatic ER+/HER2- breast cancers: results of a pilot study

(2021) Annalisa Zeppellini et al.   BMC CANCER

CXCL10 is a Tumor Microenvironment and Immune Infiltration Related Prognostic Biomarker in Pancreatic Adenocarcinoma

(2021) Huimin Huang et al.   Frontiers in Molecular Biosciences

Tumor-associated antigen-based personalized dendritic cell vaccine in solid tumor patients

(2020) Qian-Ting Wang et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

The CXCR2/CXCL2 signalling pathway – An alternative therapeutic approach in high-grade glioma

(2020) Güliz Acker et al.   EUROPEAN JOURNAL OF CANCER

Cyto-Immuno-Therapy for Cancer: A Pathway Elicited by Tumor-Targeted, Cytotoxic Drug-Packaged Bacterially Derived Nanocells

(2020) Sharon M. Sagnella et al.   CANCER CELL

Glioma stem-like cells evade interferon suppression through MBD3/NuRD complex–mediated STAT1 downregulation

(2020) Xiaoyan Zhan et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Effect of Nivolumab vs Bevacizumab in Patients With Recurrent Glioblastoma

(2020) David A. Reardon et al.   JAMA Oncology

Survival outcomes in patients with recurrent glioblastoma treated with Laser Interstitial Thermal Therapy (LITT): A systematic review

(2020) Nicola Montemurro et al.   CLINICAL NEUROLOGY AND NEUROSURGERY

Microglia/macrophages express alternative proangiogenic factors depending on granulocyte content in human glioblastoma

(2020) Anne Blank et al.   JOURNAL OF PATHOLOGY

Glioma-derived IL-33 orchestrates an inflammatory brain tumor microenvironment that accelerates glioma progression

(2020) Astrid De Boeck et al.   Nature Communications

Treatment with Luteolin Improves Lipopolysaccharide-Induced Periodontal Diseases in Rats

(2020) Giovanna Casili et al.   Biomedicines

cIMPACT‐NOW: a practical summary of diagnostic points from Round 1 updates

(2019) David N. Louis et al.   BRAIN PATHOLOGY

Inflammation and Cancer: Triggers, Mechanisms, and Consequences

(2019) Florian R. Greten et al.   IMMUNITY

Tumor-associated reactive astrocytes aid the evolution of immunosuppressive environment in glioblastoma

(2019) Dieter Henrik Heiland et al.   Nature Communications

ERK1/2 signaling regulates the immune microenvironment and macrophage recruitment in glioblastoma

(2019) Claire Lailler et al.   BIOSCIENCE REPORTS

Modulating lncRNA SNHG15/CDK6/miR-627 circuit by palbociclib, overcomes temozolomide resistance and reduces M2-polarization of glioma associated microglia in glioblastoma multiforme

(2019) Zhenzhe Li et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Hypoxic glioma-derived exosomes deliver microRNA-1246 to induce M2 macrophage polarization by targeting TERF2IP via the STAT3 and NF-κB pathways

(2019) Mingyu Qian et al.   ONCOGENE

Microglial regional heterogeneity and its role in the brain

(2019) Yun-Long Tan et al.   MOLECULAR PSYCHIATRY

Reactive Astrocytes in Glioblastoma Multiforme

(2018) Xiudong Guan et al.   MOLECULAR NEUROBIOLOGY

Multidimensional communication in the microenvirons of glioblastoma

(2018) Marike L. Broekman et al.   Nature Reviews Neurology

Microglia and Beyond: Innate Immune Cells As Regulators of Brain Development and Behavioral Function

(2018) Kathryn M. Lenz et al.   Frontiers in Immunology

The Multifarious Role of Microglia in Brain Metastasis

(2018) Manuel Sarmiento Soto et al.   Frontiers in Cellular Neuroscience

CXCL16/CXCR6 Axis Drives Microglia/Macrophages Phenotype in Physiological Conditions and Plays a Crucial Role in Glioma

(2018) Francesca Lepore et al.   Frontiers in Immunology

The roles of microglia macrophages in tumor progression of brain cancer and metastatic disease

(2017) Shih-Ying Wu   Frontiers in Bioscience-Landmark

Effect of Tumor-Treating Fields Plus Maintenance Temozolomide vs Maintenance Temozolomide Alone on Survival in Patients With Glioblastoma

(2017) Roger Stupp et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

CNS cancer: Glioblastoma subtypes revisited

(2017) Peter Sidaway   Nature Reviews Clinical Oncology

Glioma Subclassifications and Their Clinical Significance

(2017) Ricky Chen et al.   Neurotherapeutics

The Lifespan and Turnover of Microglia in the Human Brain

(2017) Pedro Réu et al.   Cell Reports

Coupled Proliferation and Apoptosis Maintain the Rapid Turnover of Microglia in the Adult Brain

(2017) Katharine Askew et al.   Cell Reports

The 2016 World Health Organization Classification of Tumors of the Central Nervous System: a summary

(2016) David N. Louis et al.   ACTA NEUROPATHOLOGICA

Microglia across the lifespan: from origin to function in brain development, plasticity and cognition

(2016) Tuan Leng Tay et al.   JOURNAL OF PHYSIOLOGY-LONDON

Microglial M1/M2 polarization and metabolic states

(2015) Ruben Orihuela et al.   BRITISH JOURNAL OF PHARMACOLOGY

STAT3 Establishes an Immunosuppressive Microenvironment during the Early Stages of Breast Carcinogenesis to Promote Tumor Growth and Metastasis

(2015) Laura M. Jones et al.   CANCER RESEARCH

The Impact of Macrophage- and Microglia-Secreted TNF  on Oncolytic HSV-1 Therapy in the Glioblastoma Tumor Microenvironment

(2015) W. H. Meisen et al.   CLINICAL CANCER RESEARCH

Temporal-Spatial Resolution Fate Mapping Reveals Distinct Origins for Embryonic and Adult Microglia in Zebrafish

(2015) Jin Xu et al.   DEVELOPMENTAL CELL

Complex alterations in microglial M1/M2 markers during the development of epilepsy in two mouse models

(2015) Melissa J. Benson et al.   EPILEPSIA

Biomarkers for glioma immunotherapy: the next generation

(2015) Jennifer S. Sims et al.   JOURNAL OF NEURO-ONCOLOGY

Current challenges in designing GBM trials for immunotherapy

(2015) Shiao-Pei Weathers et al.   JOURNAL OF NEURO-ONCOLOGY

Differential Roles of M1 and M2 Microglia in Neurodegenerative Diseases

(2015) Yu Tang et al.   MOLECULAR NEUROBIOLOGY

M1 and M2 immune activation in Parkinson’s Disease: Foe and ally?

(2015) M.S. Moehle et al.   NEUROSCIENCE

Glioblastoma multiforme: Pathogenesis and treatment

(2015) Constantinos Alifieris et al.   PHARMACOLOGY & THERAPEUTICS

Microglia Function in Central Nervous System Development and Plasticity

(2015) Dorothy P. Schafer et al.   Cold Spring Harbor Perspectives in Biology

Microglia Development and Function

(2014) Debasis Nayak et al.   Annual Review of Immunology

Neuroinflammation and M2 microglia: the good, the bad, and the inflamed

(2014) Jonathan D Cherry et al.   Journal of Neuroinflammation

A Randomized Trial of Bevacizumab for Newly Diagnosed Glioblastoma

(2014) Mark R. Gilbert et al.   NEW ENGLAND JOURNAL OF MEDICINE

Molecular Mechanisms That Influence the Macrophage M1–M2 Polarization Balance

(2014) Nan Wang et al.   Frontiers in Immunology

The Controversial Role of Microglia in Malignant Gliomas

(2013) Jun Wei et al.   Clinical & Developmental Immunology

The integrated landscape of driver genomic alterations in glioblastoma

(2013) Veronique Frattini et al.   NATURE GENETICS

Innate and adaptive immune cells in the tumor microenvironment

(2013) Thomas F Gajewski et al.   NATURE IMMUNOLOGY

Differential distribution and activation of microglia in the brain of male C57BL/6J mice

(2012) Ting-Ting Yang et al.   Brain Structure & Function

Tumor-Associated Microglia/Macrophages Enhance the Invasion of Glioma Stem-like Cells via TGF- 1 Signaling Pathway

(2012) X.-z. Ye et al.   JOURNAL OF IMMUNOLOGY

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(2012) Salvatore Coniglio et al.   MOLECULAR MEDICINE

The molecular profile of microglia under the influence of glioma

(2012) W. Li et al.   NEURO-ONCOLOGY

Microglia/Macrophage Polarization Dynamics Reveal Novel Mechanism of Injury Expansion After Focal Cerebral Ischemia

(2012) Xiaoming Hu et al.   STROKE

Hallmarks of Cancer: The Next Generation

(2011) Douglas Hanahan et al.   CELL

Enhanced anti-glioblastoma activity of microglia by AAV2-mediated IL-12 through TRAIL and phagocytosis in vitro

(2011) Chiu   ONCOLOGY REPORTS

Physiology of Microglia

(2011) Helmut Kettenmann et al.   PHYSIOLOGICAL REVIEWS

Macrophage Diversity Enhances Tumor Progression and Metastasis

(2010) Bin-Zhi Qian et al.   CELL

Microglia promote colonization of brain tissue by breast cancer cells in a Wnt-dependent way

(2010) Tobias Pukrop et al.   GLIA

Glioma cancer stem cells induce immunosuppressive macrophages/microglia

(2010) Adam Wu et al.   NEURO-ONCOLOGY

Astrocytes: biology and pathology

(2009) Michael V. Sofroniew et al.   ACTA NEUROPATHOLOGICA

Tumor-associated macrophage/microglia infiltration in human gliomas is correlated with MCP-3, but not MCP-1

(2009) Saio   INTERNATIONAL JOURNAL OF ONCOLOGY

Heterogeneity of Microglial Activation in the Innate Immune Response in the Brain

(2009) Carol A. Colton   Journal of Neuroimmune Pharmacology

Molecular dissection of reactive astrogliosis and glial scar formation

(2009) Michael V. Sofroniew   TRENDS IN NEUROSCIENCES

The interface between glial progenitors and gliomas

(2008) Peter Canoll et al.   ACTA NEUROPATHOLOGICA

Comprehensive genomic characterization defines human glioblastoma genes and core pathways

(2008) Roger McLendon et al.   NATURE

IDENTIFICATION OF A2B5+CD133− TUMOR-INITIATING CELLS IN ADULT HUMAN GLIOMAS

(2008) Alfred T. Ogden et al.   NEUROSURGERY

Glial Progenitor-Like Phenotype in Low-Grade Glioma and Enhanced CD133-Expression and Neuronal Lineage Differentiation Potential in High-Grade Glioma

(2008) Johan Rebetz et al.   PLoS One

An Integrated Genomic Analysis of Human Glioblastoma Multiforme

(2008) D. W. Parsons et al.   SCIENCE